Cell Death & Differentiation. 19 (8): 1308-16. doi:10.1038/cdd.2012.5. PMC 3392634. PMID 22301916. Valente EM, Abou-Sleiman PM ... Cell. 154 (4): 737-47. doi:10.1016/j.cell.2013.07.030. PMC 3950538. PMID 23953109. Osgerby L, Lai YC, Thornton PJ, Amalfitano J ... In December 2017, niclosamide, an anthelmintic drug, was identified as a potent activator of PINK1 in cells and in neurons. ... It is thought to protect cells from stress-induced mitochondrial dysfunction. PINK1 activity causes the parkin protein to bind ...
... levels and intracellular localization in the CV-1 cell cycle". Cell Growth & Differentiation. 9 (8): 651-65. PMID 9716182. ... In the brain Pur-alpha plays a role in diseases involving glial cells, cells that support nerve cells, as well as diseases ... These cell cycle effects are consistent with an interaction between Pur-alpha and CDK, cell cycle-dependent protein kinases. ... Although HIV-1 is not usually found in these glial cells, HIV-1 proteins can pass through cell membranes to enter them. JCV is ...
Wajant, H.; Pfizenmaier, K.; Scheurich, P. (2003). "Tumor necrosis factor signaling". Cell Death & Differentiation. 10 (1): 45- ... The main source of TNF (tumor necrosis factor) are cells in the immune system called macrophages which produce it in response ... TNF helps activate other immune cells and plays a major role in initiation of inflammation. Individuals with TRAPS have a ...
... and Cell Death & Differentiation. His work in the field of corneal collagen cross-linking has led him to receive a number of ... Cell Death & Differentiation. 8 (8): 859-867. doi:10.1038/sj.cdd.4400871. PMID 11526439. Wenzel A, Reme CE, Williams TP, Hafezi ... Cell Death & Differentiation. 6 (10): 934-936. doi:10.1038/sj.cdd.4400574. PMID 10617374. Fleischmann A, Hafezi F, Elliott C, ... work that was published in IOVS and Cell Death & Differentiation, respectively. c-Fos and Fra1 are both components of the ...
These molecules are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene ... Cell Growth & Differentiation. 5 (11): 1173-83. PMID 7848919. Kato JY, Matsuoka M, Strom DK, Sherr CJ (Apr 1994). "Regulation ... Discoidin domain receptor family, member 1, also known as DDR1 or CD167a (cluster of differentiation 167a), is a human gene. ... Johnson JD, Edman JC, Rutter WJ (Jun 1993). "A receptor tyrosine kinase found in breast carcinoma cells has an extracellular ...
Cell Growth & Differentiation. 8 (7): 811-20. PMID 9218875. Novak B, Tyson JJ (December 1993). "Numerical analysis of a ... Curiously, G2 phase is not a necessary part of the cell cycle, as some cell types (particularly young Xenopus embryos and some ... G2 phase is a period of rapid cell growth and protein synthesis during which the cell prepares itself for mitosis. ... Finally, the continuation of the cell cycle requires persisting oscillations in cyclin-B/CDK1 activity as the cell and its ...
... undergo cell differentiation through a variety of mechanisms based on cell-cell communication. Suberites are key ... Suberites consist of many telomerase-positive cells, which means the cells are essentially immortal, barring cell death signal ... Differentiation capacity of epithelial cells in the sponge Suberites domuncula. Cell & Tissue Research 316, 271 (2004). H. C. ... Their apoptotic cells are similar to homologous to mammalian. However, maintenance of long-lived cells involves proteins such ...
Cell Growth & Differentiation. 6 (12): 1651-8. PMID 9019171. Kharbanda S, Saleem A, Shafman T, Emoto Y, Taneja N, Rubin E, ... "Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation". ... "Differential regulation of cell motility and invasion by FAK". The Journal of Cell Biology. 160 (5): 753-67. doi:10.1083/jcb. ... alters cell morphology upon translocation to the cell membrane". Molecular and Cellular Biology. 16 (4): 1770-6. doi:10.1128/ ...
BTG2 induces their differentiation. In fact, in the neuronal PC12 cell line BTG2 is not able to trigger differentiation by ... Götz M, Huttner WB (October 2005). "The cell biology of neurogenesis". Nature Reviews Molecular Cell Biology. 6 (10): 777-88. ... Cell Growth & Differentiation. 7 (10): 1327-36. PMID 8891336. Archived from the original on 2015-05-18. Retrieved 2010-03-16. ... while in vivo BTG2 is fully able to induce differentiation of progenitor cells, i.e., during embryonic development in the ...
... is involved in regulating cell adhesion, migration, and differentiation, as well as other cellular processes. It interacts ... CIB1 has also been shown to promote the growth of prostate cancer cells and the invasion of ovarian cancer cells. Targeting ... Cell Death & Differentiation. 28 (3): 1026-1040. doi:10.1038/s41418-020-00635-5. ISSN 1476-5403. PMC 7937682. Qin, Xuying; Sun ... including genes involved in cell proliferation and differentiation. CIB1 has been shown to interact with RAC3, PSEN2, DNA-PKcs ...
Cell Death & Differentiation. 23 (4): 681-694. doi:10.1038/cdd.2015.137. ISSN 1350-9047. PMC 4986640. PMID 26494467. Yu, JW; ... FLICE-like inhibitory proteins (FLIPs) are cell inhibitors capable of stopping the death receptors' signal, which cause cell ... "Structures, Domains and Function in Cell Death". Elmore, Susan (2007). "Apoptosis: A Review of Programmed Cell Death". ... depending on the necessity of the cell. Scientists find that they are a mechanism that can regulate cell life and is important ...
15 April 2011). "Morphological classification of plant cell deaths". Cell Death & Differentiation. 18 (8): 1241-1246. doi: ... Her research investigates the cellular mechanisms involved in the regulation of the cell-cell recognition system of self- ... Vernonica "Noni" Elsa Franklin-Tong FRS is an English plant cell biologist who is Emeritus Professor at the University of ... Franklin-Tong developed an in vitro bioassay that allowed for the first investigations into the cell biology of self- ...
Cell Death & Differentiation. 20 (5): 784. doi:10.1038/cdd.2013.18. ISSN 1476-5403. PMC 3619240. PMID 23449392. Bose, Julie S ... A Dihydrobenzofuran Lignan Induces Cell Death by Modulating Mitochondrial Pathway and G2/M Cell Cycle Arrest". Journal of ... He is known for his studies on cell signaling and apoptosis. The Department of Biotechnology of the Government of India awarded ... sensitizes chemotherapeutic agents-mediated apoptosis in constitutive NF-kappaB-expressing and chemoresistant cells". ...
Cell Growth & Differentiation. 5 (10): 1127-35. PMID 7848914. Miyake A (Mar 1995). "A truncated isoform of human CCK-B/gastrin ... "Endocytosis of gastrin in cancer cells expressing gastrin/CCK-B receptor". Cell and Tissue Research. 287 (2): 325-33. doi: ... Kulaksiz H, Arnold R, Göke B, Maronde E, Meyer M, Fahrenholz F, Forssmann WG, Eissele R (Feb 2000). "Expression and cell- ... A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. CCK ...
"About the journal". Cell Death & Differentiation. Retrieved 2016-11-20. Beall, Jeffrey (19 April 2016). "Oncotarget's Peer ... Blagosklonny is editor-in-chief of Aging, Cell Cycle, and Oncotarget. In addition, he is associate editor of Cancer Biology & ... Therapy and a member of the editorial board of Cell Death & Differentiation. The peer review process employed by Oncotarget has ... "Editorial Board". Cell Cycle. Taylor & Francis. Retrieved 2016-11-20. "Editorial Board". Oncotarget. Retrieved 2016-11-20. " ...
Cell Death & Differentiation. 8 (7): 767-70. doi:10.1038/sj.cdd.4400880. PMID 11464221. Teichmann, Joachim; Voglau, Marcus J.; ... on antigen-reactive B-cells. These T-helper cells then stimulate B-cells to multiply and mature into plasma cells that make IgA ... B-cells with surface IgM that react to transglutaminase can present it with bound gliadin peptides to T-cells which stimulate B ... For most antigens, T-cells specific to those antigens develop; for autoimmunity, either autoreactive T-cells are not suppressed ...
Cell Death & Differentiation. 17 (3): 381-97. doi:10.1038/cdd.2009.195. PMID 20019744. Tennant, I; Pound, JD; Marr, LA (May ... apoptotic cells, unlike necrotic cells, do not trigger the unwanted immune response. Eat-me signals mark the apoptotic cells ... On a viable cell, phosphatidylserine is only present in the inner layer of the cell membrane - this is maintained by ... These patterns include eat-me signals on the apoptotic cells, loss of don't-eat-me signals on viable cells and come-get-me ...
... cell growth and differentiation, gene transcription, signal transduction and apoptosis. Subsequently, a compromised proteasome ... For instance, in breast cancer cells, a high expression level of the PSMB7 protein suggests a shorter survival than in cells ... UPS proteolysis plays a major role in responses of cancer cells to stimulatory signals that are critical for the development of ... Kleiger G, Mayor T (June 2014). "Perilous journey: a tour of the ubiquitin-proteasome system". Trends in Cell Biology. 24 (6): ...
Cell Growth & Differentiation. 11 (3): 137-47. PMID 10768861. Hartley JL, Temple GF, Brasch MA (November 2000). "DNA cloning ... "Role of the basic helix-loop-helix transcription factor p48 in the differentiation phenotype of exocrine pancreas cancer cells ... This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in ... Cytogenetics and Cell Genetics. 68 (3-4): 235-8. doi:10.1159/000133921. PMID 7842744. Doyle K, Zhang Y, Baer R, Bina M (April ...
Cell Death & Differentiation. 29 (3): 670-686. doi:10.1038/s41418-021-00883-z. ISSN 1476-5403. PMC 8901757. PMID 34663908. ... Hetz, Claudio; Papa, Feroz R. (January 2018). "The Unfolded Protein Response and Cell Fate Control". Molecular Cell. 69 (2): ... EBC-46 Rogers TB, Inesi G, Wade R, Lederer WJ (1995). "Use of thapsigargin to study Ca2+ homeostasis in cardiac cells". Biosci ... Non-resolved ER stress can cumulatively lead to cell death. Prolonged store depletion can protect against ferroptosis via ...
"Mitochondrial maturation drives germline stem cell differentiation in Caenorhabditis elegans". Cell Death and Differentiation. ... Kourtis N, Tavernarakis N (2009). "Autophagy and cell death in model organisms". Cell Death and Differentiation. 16 (1): 21-30 ... Papandreou ME, Tavernarakis N (2019). "Nucleophagy: from homeostasis to disease". Cell Death and Differentiation. 26 (4): 630- ... Samara C, Syntichaki P, Tavernarakis N (2008). "Autophagy is required for necrotic cell death in Caenorhabditis elegans". Cell ...
Many factors and components play a role in the cell cycle of K562 cells in terms of growth, cell differentiation, and apoptosis ... The growth of these leukemic cells are controlled by either initiating cell differentiation or apoptosis to occur. Cell ... "p53-mediated differentiation of the erythroleukemia cell line K562". Cell Growth & Differentiation. 11 (6): 315-324. PMID ... This gene targets the cyclin-dependent kinase inhibitor, p21, and causes cell differentiation, cell cycle arrest in G1, and ...
... cell growth and differentiation, gene transcription, signal transduction and apoptosis. Subsequently, a compromised proteasome ... UPS proteolysis plays a major role in responses of cancer cells to stimulatory signals that are critical for the development of ... Kleiger G, Mayor T (June 2014). "Perilous journey: a tour of the ubiquitin-proteasome system". Trends in Cell Biology. 24 (6): ... Goff SP (August 2003). "Death by deamination: a novel host restriction system for HIV-1". Cell. 114 (3): 281-3. doi:10.1016/ ...
Cell Growth & Differentiation. 9 (8): 629-37. PMID 9716180. Trofimova-Griffin ME, Juchau MR (November 1998). "Expression of ... CYP26A1 is over-expressed in colorectal cancer cells compared to normal colonic epithelium but is of no independent prognostic ... expression on the CYP26-mediated catabolism of all-trans retinoic acid and cell proliferation in head and neck squamous cell ... is highly specific for all-trans-RA and can be induced through RA receptors in human breast and colon carcinoma cells". ...
Cell Growth & Differentiation. 4 (12): 1005-12. PMID 8117614. Coghlan VM, Langeberg LK, Fernandez A, Lamb NJ, Scott JD (Mar ... and cell cycle-dependent subcellular distribution of the A-kinase anchoring protein, AKAP95". Experimental Cell Research. 238 ( ... The Journal of Cell Biology. 147 (6): 1167-80. doi:10.1083/jcb.147.6.1167. PMC 2168084. PMID 10601332. Takahashi M, Shibata H, ... Journal of Cell Science. 112 (16): 2725-36. doi:10.1242/jcs.112.16.2725. PMID 10413680. Dong F, Feldmesser M, Casadevall A, ...
Cell Growth & Differentiation. 5 (8): 811-25. PMID 7986747. Vladimirov SN, Ivanov AV, Karpova GG, Musolyamov AK, Egorov TA, ... Cell. 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573. v t e (Articles with short description, ... Lee WJ, Keefer K, Hollenbeak CS, Stack BC (Oct 2004). "A new assay to screen for head and neck squamous cell carcinoma using ... Scurry WC, Stack BC (Dec 2007). "Role of metalloproteins in the clinical management of head and neck squamous cell carcinoma". ...
... enhancing the differentiation of memory T cells into effector cells, i.e. it induces IFN-γ production and cell proliferation. ... cells, stem memory TSCM cells, and virtual memory T cells. The single unifying theme for all memory T cell subtypes is that ... Since memory T cells have shorter half-lives than naïve T cells do, continuous replication and replacement of old cells are ... Historically, memory T cells were thought to belong to either the effector (TEM cells) or central memory (TCM cells) subtypes, ...
"TCTP protects from apoptotic cell death by antagonizing bax function". Cell Death & Differentiation. 15 (8): 1211-1220. doi: ... Aug 2008). "TCTP protects from apoptotic cell death by antagonizing bax function". Cell Death Differ. 15 (8): 1211-20. doi: ... Aug 2008). "TCTP protects from apoptotic cell death by antagonizing bax function". Cell Death Differ. 15 (8): 1211-20. doi: ... TCTP (Translationally Controlled Tumor Protein was identified in a screen between tumor cells and revertant cells. Inhibition ...
... cell growth and differentiation, gene transcription, signal transduction and apoptosis. Subsequently, a compromised proteasome ... UPS proteolysis plays a major role in responses of cancer cells to stimulatory signals that are critical for the development of ... Kleiger G, Mayor T (June 2014). "Perilous journey: a tour of the ubiquitin-proteasome system". Trends in Cell Biology. 24 (6): ... Goff SP (August 2003). "Death by deamination: a novel host restriction system for HIV-1". Cell. 114 (3): 281-3. doi:10.1016/ ...
Friesen, Paul (February 2001). "Lois K. Miller". Cell Death & Differentiation. 8 (2): 111-112. doi:10.1038/sj.cdd.4400830. PMID ... She focused her research on baculoviruses and programmed cell death. In 1991, her team at the University of Georgia discovered ... "Prevention of apoptosis by a baculovirus gene during infection of insect cells". Science. 254 (5036): 1388-90. Bibcode:1991Sci ...
Cell Growth & Differentiation. 3 (8): 541-8. PMID 1390339. "Entrez Gene: ST5 suppression of tumorigenicity 5". "OrthoMaM ... Cell. 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573. v t e (Articles with short description, ... This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this ... human chromosome 11 gene which is differentially regulated in tumorigenic and nontumorigenic somatic cell hybrids of HeLa cells ...
Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Four alternatively spliced transcript ... Cell Growth & Differentiation. 6 (12): 1651-8. PMID 9019171. Kharbanda S, Saleem A, Shafman T, Emoto Y, Taneja N, Rubin E, ... Liu J, Lin A (2007). "Wiring the cell signaling circuitry by the NF-kappa B and JNK1 crosstalk and its applications in human ... Davis RJ (2000). "Signal transduction by the JNK group of MAP kinases". Cell. 103 (2): 239-52. doi:10.1016/S0092-8674(00)00116- ...
Cell Growth & Differentiation. 4 (10): 821-30. PMID 8274451. Overview of all the structural information available in the PDB ... "Nucleolar release of Hand1 acts as a molecular switch to determine cell fate". Nature Cell Biology. 9 (10): 1131-41. doi: ... "Plk4-induced centriole biogenesis in human cells" (PDF). Developmental Cell. 13 (2): 190-202. doi:10.1016/j.devcel.2007.07.002 ... "Small-molecule inducer of cancer cell polyploidy promotes apoptosis or senescence: Implications for therapy". Cell Cycle. 9 (16 ...
... but cell lineage and differentiation inevitably led to the study of cell fate: One aspect of the cell lineage particularly ... These cells are absent because they undergo programmed cell death - Horvitz: "Worms, Life and Death," 2002. Programmed cell ... protects cells from programmed cell death, so its expression conveys a life-or-death decision on individual cells. In 1992, it ... Vaux DL (April 2002). "Apoptosis timeline". Cell Death & Differentiation. 9 (4): 349-54. doi:10.1038/sj.cdd.4400990. PMID ...