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*  Catechol-O-methyl transferase
... and various drugs and substances having a catechol structure. In humans, catechol-O-methyltransferase protein is encoded by the ... Any compound having a catechol structure, like catecholestrogens and catechol-containing flavonoids, are substrates of COMT. ... Fan JB, Zhang CS, Gu NF, Li XW, Sun WW, Wang HY, Feng GY, St Clair D, He L (January 2005). "Catechol-O-methyltransferase gene ... Catechol-O-methyltransferase (COMT; EC 2.1.1.6) is one of several enzymes that degrade catecholamines (such as dopamine, ...
*  Pyrogallol
Gallic acid Catechol Syringol Gallacetophenone (2,3,4-trihydroxyacetophenone) Fiege, Helmut; Heinz-Werner, Voges; Hamamoto, ...
*  Catechol
... catechol was listed as pyrocatechol. In 1879, the Journal of the Chemical Society recommended that catechol be called "catechol ... Catechol occurs as feathery white crystals that are very rapidly soluble in water. Catechol was first isolated in 1839 by Edgar ... Catechol moieties are also found widely within the natural world. Arthropod cuticle consists of chitin linked by a catechol ... Iron-containing dioxygenase enzymes catalyze the cleavage of catechol. Catechol is produced by a reversible two-electron, two- ...
*  Catechol dioxygenase
... s are metalloprotein enzymes that carry out the oxidative cleavage of catechols. This class of enzymes ... An example of the reaction carried out by catechol 1,2-dioxygenase is the formation of cis,cis-muconic acid from catechol, ... catechol 2,3-dioxygenase (EC 1.13.11.2), and protocatechuate 3,4-dioxygenase (EC 1.13.11.3). The active site of catechol ... The Pseudomonas putida xylE gene, which encodes catechol 2,3-dioxygenase, is often used as a reporter to quantitate gene ...
*  Catechol estrogen
A catechol estrogen is a steroidal estrogen that contains catechol (1,2-dihydroxybenzene) within its structure. The catechol ... Similarly to estradiol and estrone, catechol estrogens possess estrogenic activity. 2-Hydroxylated catechol estrogens are weak ... The catechol estrogens are formed from estradiol and estrone by cytochrome P450 enzymes predominantly in the liver but also in ... Under poor conditions of inactivation by phase II enzymes, catechol estrogens can undergo oxidation to reactive quinones and ...
*  Catechol oxidase
In plants, catechol oxidase plays a key role in enzymatic browning by catalyzing the oxidation of catechol to o-quinone in the ... As catechol enters the active site, a proton is abstracted from one of the alcohols. The catechol coordinates with a Cu(II) ... The coordinated hydroxide ion abstracts another proton from catechol to form water, and the catechol is oxidized to o-quinone. ... In this state, the enzyme active site is in a ternary catechol oxidase-O22−-catechol complex. Two electrons are transferred ...
*  Chloridazon-catechol dioxygenase
... (EC 1.13.11.36) is an enzyme that catalyzes the chemical reaction 5-amino-4-chloro-2-(2,3- ... Chloridazon-catechol dioxygenase from Phenylobacterium immobilis DSM 1986". Eur. J. Biochem. 125 (3): 579-84. doi:10.1111/j. ... Muller R, Haug S, Eberspacher J, Lingens F (1977). "[Catechol 2,3-dioxygenase from pyrazon-degrading bacteria (author's transl ...
*  Catechol oxidase (dimerizing)
In enzymology, a catechol oxidase (dimerizing) (EC 1.1.3.14) is an enzyme that catalyzes the chemical reaction 4 catechol + 3 ... The systematic name of this enzyme class is catechol:oxygen oxidoreductase (dimerizing). Nair PM; Vining LC (1964). "Enzymic ... the two substrates of this enzyme are catechol and O2, whereas its two products are [[dibenzo[1,4]dioxin-2,3-dione]] and H2O. ... oxidation of catechol to diphenylenedioxide-2,3-quinone". Arch. Biochem. Biophys. 106: 422-427. doi:10.1016/0003-9861(64)90210- ...
*  Catechol 2,3-dioxygenase
... (EC 1.13.11.2, 2,3-pyrocatechase, catechol 2,3-oxygenase, catechol oxygenase, metapyrocatechase, ... Catechol 2,3-dioxygenase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular Biology ... Kojima, Y.; Itada, N.; Hayaishi, O. (1961). "Metapyrocatechase: a new catechol-cleaving enzyme". J. Biol. Chem. 236: 2223-2228 ... pyrocatechol 2,3-dioxygenase) is an enzyme with systematic name catechol:oxygen 2,3-oxidoreductase (decyclizing). This enzyme ...
*  Catechol 1,2-dioxygenase
Catechol 1,2- dioxygenase (EC 1.13.11.1, 1,2-CTD, catechol-oxygen 1,2-oxidoreductase, 1,2-pyrocatechase, catechase, catechol 1, ... Pascal, R; Huang, O (1986). "Reactions of 3-ethylcatechol and 3-(methylthio)catechol with catechol dioxygenases". Arch. Biochem ... 2-dioxygenase and catechol 2,3-dioxygenase (2,3-CTD). The two enzymes were identified to be a part of two separate catechol ... a family of catechol dioxygenases that cleaves the bond between the phenolic hydroxyl groups of catechol using an Fe3+ cofactor ...
*  Piperonal
Synthesis from catechol requires an additional step, Williamson ether synthesis using dichloromethane. Piperonal, like all ... Piperonal can be prepared by oxidizing isosafrole or by using a multistep sequence from catechol or 1,2-methylenedioxybenzene. ... doi:10.1016/S0040-4039(00)88578-0. Bonthrone, W. & Cornforth, J. (1969). "The methylenation of catechols". Journal of the ...
*  1,3-Benzodioxole
doi:10.2174/1389200003339270 Bonthrone, W. & Cornforth, J. (1969). "The methylenation of catechols". Journal of the Chemical ... 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes. 1,4-Benzodioxine Methylenedioxy Safrole ...
*  Dakin oxidation
Catechol, for example, is synthesized from o-hydroxy and o-alkoxy phenyl aldehydes and ketones, and is used as the starting ... Dakin, H.D. (1923). "Catechol". Organic Syntheses. 3: 28. doi:10.15227/orgsyn.003.0028. Surrey, Alexander R. (1946). " ...
*  Salicylaldehyde
Dakin, H. D. (1923). "Catechol" (PDF). Organic Syntheses. 3: 28. ; Collective Volume, 1, p. 149 Burgstahler, A. W.; Worden, L. ... Salicylaldehyde is used to make the following: Oxidation with hydrogen peroxide gives catechol (1,2-dihydroxybenzene) (Dakin ...
*  History of catecholamine research
In the case the catecholamines, however, the enzymes of degradation monoamine oxidase and catechol-O-methyl transferase, like ... In this respect, ″amino-ethanol-catechol″ - noradrenaline - mimicked sympathetic nerves more closely than adrenaline did. The ... Julius Axelrod (1962). "O-Methylation of epinephrine and other catechols". Science. 126 (3270): 400-401. doi:10.1126/science. ... noradrenaline and adrenaline were O-methylated by catechol-O-methyl transferase. To fill the gap completely, however, the role ...
*  Methyltransferase
Catechol-O-methyltransferase (COMT) degrades a class of molecules known as catcholamines that includes dopamine, epinephrine, ... "COMT catechol-O-methyltransferase". NCBI Genetic Testing Registry. Retrieved 18 February 2014. Ragsdale, S.W. "Catalysis of ... Examples include: Catechol-O-methyl transferase DNA methyltransferase Histone methyltransferase 5-Methyltetrahydrofolate- ...
*  Polyphenol oxidase
... catechol oxidases). A mixture of monophenol oxidase and catechol oxidase enzymes is present in nearly all plant tissues, and ... catechol oxidase "Polyphenol Oxidase". Worthington Enzyme Manual. Retrieved 13 September 2011. Mayer, AM (November 2006). " ...
*  Siderocalin
... allowing siderocalin to bind to the iron-catechol complex. Catechols can be bound by siderocalin, in the form of free ligands, ... Mammalian siderophores, specifically catechols, can be found in the human gut and in siderophores, such as enterobactin, and ... Catechol resembling molecules can act as iron ligands in the cell and in systematic circulation, ... Rogers HJ (Mar 1973). "Iron-Binding Catechols and Virulence in Escherichia coli". Infection and Immunity. 7 (3): 445-56. PMC ...
*  Siderophore
... the catechol-type siderophores, agrobactin; and the mixed ligand catechol-hydroxamate-hydroxy acid siderophores biosynthesized ...
*  Methoxy group
Catechol-O-methyl transferase (COMT). A large number of natural products in plants, e.g. lignins, are generated via catalysis ...
*  Anthranilate 1,2-dioxygenase (deaminating, decarboxylating)
Kobayashi S, Hayaishi O (1970). "Anthranilic acid conversion to catechol (Pseudomonas)". Methods Enzymol. 17A: 505-510. doi: ... catechol + CO2 + NAD(P)+ + NH3 The 5 substrates of this enzyme are anthranilate, NADH, NADPH, H+, and O2, whereas its 5 ... "Enzymatic formation of catechol from anthranilic acid". J. Biol. Chem. 239: 2204-2211. PMID 14209949. Molecular and Cellular ... products are catechol, CO2, NAD+, NADP+, and NH3. This enzyme belongs to the family of oxidoreductases, specifically those ...
*  Muconate lactonizing enzyme
3. Enzymes of the catechol pathway". J. Biol. Chem. 241: 3795-3799. PMID 5330966. Ornston, L.N. (1970). "Conversion of catechol ... Ornston, L.N. (1966). "The conversion of catechol and protocatechuate to β-ketoadipate by Pseudomonas putida. ... catechol and protocatechuate, to citric acid cycle intermediates as a part of the β-ketoadipate pathway in soil microbes. Some ...
*  3-O-Methyldopa
... is a major metabolite of L-3,4-dihydroxyphenylalanin (L-DOPA) and is formed by catechol O-methyltransferase ( ... This process is catalyzed by catechol O-methyltransferase methylates (COMT). The action of the enzyme makes it possible the ... Tai, C. H.; Wu, R. M. (2002). "Catechol-O-methyltransferase and Parkinson's disease". Acta medica Okayama. 56 (1): 1-6. PMID ... L-DOPA Entacapone Tolcapone Catechol-O-methyl transferase Parkinson's disease Parkinson's Disease and movement disorders. ...
*  Muconolactone Delta-isomerase
3. Enzymes of the catechol pathway". J. Biol. Chem. 241 (16): 3795-9. PMID 5330966. Ornston LN (1970). "Conversion of catechol ... Ornston LN (1966). "The conversion of catechol and protocatechuate to beta-ketoadipate by Pseudomonas putida. ...
*  Cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
I Enzymatic formation of catechol from benzene". Biochemistry. 7 (7): 2653-62. doi:10.1021/bi00847a031. PMID 4298226. Molecular ... catechol + NADH + H+ Thus, the two substrates of this enzyme are cis-1,2-dihydrobenzene-1,2-diol and NAD+, whereas its 3 ... products are catechol, NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH- ...