Her group also characterized redundancies between caspase-1 and caspase-8 and between NLRP3 and caspase-8 in autoinflammatory ... Kanneganti's lab showed compensatory roles for NLRP3/caspase-1 and caspase-8 in the regulation of IL-1β production in ... Her lab identified caspase-8 and FADD as expression and activation regulators of both the canonical and non-canonical NLRP3 ... This finding went against the dogma that existed at that time that caspase-8 and FADD were involved only in apoptosis. ...

... induces a caspase-independent autophagic cell death". Cell Death and Differentiation. 10 (7): 798-807. doi:10.1038/sj.cdd. ... 87 (8): 3244-7. Bibcode:1990PNAS...87.3244F. doi:10.1073/pnas.87.8.3244. PMC 53872. PMID 2326282. Dang S, Sun L, Huang Y, Lu F ... 261 (2): 484-7. doi:10.1006/bbrc.1999.1060. PMID 10425211. Munroe PB, Mitchison HM, O'Rawe AM, Anderson JW, Boustany RM, Lerner ... 38 (4): 452-7. doi:10.1038/ng1764. hdl:11379/29243. PMID 16550171. S2CID 836017. Vázquez-Mellado J, Jiménez-Vaca AL, Cuevas- ...

"Suppression of caspase 8 activity by a coronin 1-PI3Kδ pathway promotes T cell survival independently of TCR and IL-7 signaling ... 13 (7): 510-518. doi:10.1038/nri3465. PMID 23765056. S2CID 38179365. Mueller, Philipp; Massner, Jan; Jayachandran, Rajesh; ... 13 (7): 510-518. doi:10.1038/nri3465. PMID 23765056. S2CID 38179365. Jayachandran, Rajesh; Gumienny, Aleksandra; Bolinger, ...

Büki, A.; Okonkwo, D. O.; Wang, K. K.; Povlishock, J. T. (2000). "Cytochrome c release and caspase activation in traumatic ... and caspase activation". FASEB Journal. 14 (7): 847-858. doi:10.1096/fasebj.14.7.847. PMID 10783138. S2CID 2089247. Nicholls, D ... 1368 (1): 7-18. doi:10.1016/s0005-2736(97)00175-2. PMID 9459579. Stavrovskaya, I. G.; Kristal, B. S. (2005). "The powerhouse ...

... the lambda-holin protein causes caspase-independent non-apoptotic cell death of eukaryotic cells". Cellular Microbiology. 9 (7 ...

"Lens-specific deletion of the Msx2 gene increased apoptosis by enhancing the caspase-3/caspase-8 signaling pathway". The ... 276 (7): 5331-8. doi:10.1074/jbc.M008590200. PMID 11084035. Shirakabe K, Terasawa K, Miyama K, Shibuya H, Nishida E (October ... 46 (7): 2843-2855. doi:10.1177/0300060518774687. PMC 6124292. PMID 29921154. Melville H, Wang Y, Taub PJ, Jabs EW (December ... and a highly polymorphic STRP into the 7-10 Mb YAC contig of 5q34-q35". Human Genetics. 97 (3): 399-403. doi:10.1007/BF02185781 ...

"Activation of a caspase-9-mediated apoptotic pathway by subcellular redistribution of the novel caspase recruitment domain ... Isoform 3 is an inhibitory isoform, so that it only co-localizes with caspase-1, but not with NLRs. Isoform 4 is not able to ... Conway KE, McConnell BB, Bowring CE, Donald CD, Warren ST, Vertino PM (2000). "TMS1, a novel proapoptotic caspase recruitment ... Moriai R, Tsuji N, Kobayashi D, Yagihashi A, Namiki Y, Takahashi H, Watanabe N (2003). "A proapoptotic caspase recruitment ...

... particularly caspase-3. Oligonuclosomal DNA fragmentation is initiated by caspase-activated deoxyribonuclease following caspase ... In contrast, the oncotic pathway has been shown to be caspase-3 independent. The primary determinant of cell death occurring ... Enari, M., Sakahira, H., Yokoyama, H., Okawa, K., Iwamatsu, A., & Nagata, S. (1998). A caspase-activated DNase that degrades ... Earnshaw, W. C., Martins, L. M., & Kaufmann, S. H. (1999). Mammalian caspases: structure, activation, substrates, and functions ...

Tang D, Gururajan R, Kidd VJ (June 1998). "Phosphorylation of PITSLRE p110 isoforms accompanies their processing by caspases ... 7 (3): 370-5. doi:10.1038/ng0794-370. PMID 7920654. S2CID 2065302. Gururajan R, Lahti JM, Grenet J, Easton J, Gruber I, Ambros ... 272 (18): 11694-7. doi:10.1074/jbc.272.18.11694. PMID 9115219. Loyer P, Trembley JH, Lahti JM, Kidd VJ (June 1998). "The RNP ... doi:10.1016/S1097-2765(00)80239-7. PMID 10882096. Zhang SW, Xu SL, Cai MM, Yan J, Zhu XY, Hu Y, Gu JX (May 2001). "Effect of ...

... induces caspase-dependent apoptosis in a TRAIL-mediated manner, and potentiates the pro-apoptotic effects of ... Battle, T. E.; Arbiser, J; Frank, DA (2005). "The natural product honokiol induces caspase-dependent apoptosis in B-cell ... "Honokiol overcomes conventional drug resistance in human multiple myeloma by induction of caspase-dependent and -independent ... 265 (7): 4111-5. doi:10.3389/fneur.2013.00130. PMC 3769637. PMID 2406271. Lee, Young-Jung; Lee, Yoot Mo; Lee, Chong-Kil; Jung, ...

"Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment". Cell. 94 (2 ... "Identification of a caspase-2 isoform that behaves as an endogenous inhibitor of the caspase cascade". Cancer Res. 60 (24): ... "Identification of a caspase-2 isoform that behaves as an endogenous inhibitor of the caspase cascade". Cancer Res. 60 (24): ... Chaudhary PM, Eby MT, Jasmin A, Kumar A, Liu L, Hood L (2000). "Activation of the NF-kappaB pathway by caspase 8 and its ...

Quignon F, De Bels F, Koken M, Feunteun J, Ameisen JC, de Thé H (November 1998). "PML induces a novel caspase-independent death ... Retinoic acid induces a caspase-3 mediated degradation of the same chimera. In HHV, ICP0 disrupts nuclear dots in the early ... October 1998). "Caspases mediate retinoic acid-induced degradation of the acute promyelocytic leukemia PML/RARalpha fusion ... 20 (8): 660-7. doi:10.1002/(SICI)1521-1878(199808)20:8. 3.0.CO;2-M. PMID 9780840. S2CID 46499841. Bloch DB, Chiche JD, Orth D, ...

... encoding caspase recruitment domain-containing protein 10 CBX7 (22q13) encoding chromobox protein homolog 7 CDC42EP1: CDC42 ... Retrieved 7 August 2019. "Chromosome 22: Chromosome summary - Homo sapiens". Ensembl Release 88. 29 March 2017. Retrieved 19 ... ISBN 978-3-318-02253-7. Sethakulvichai, W.; Manitpornsut, S.; Wiboonrat, M.; Lilakiatsakun, W.; Assawamakin, A.; Tongsima, S. ( ... encoding protein Ribosomal RNA-processing protein 7 homolog A RTCB: encoding protein RNA 2',3'-cyclic phosphate and 5'-OH ...

P35 has been shown to be a caspase inhibitor with a very wide spectrum of activity both in regard to inhibited caspase types ... However, unlike other caspase substrate proteins, the fragments of P35 do not dissociate from the caspase after cleavage. ... The mechanism of caspase inhibition was discovered by Guozhou Xu in the team of Hao Wu at the Department of Biochemistry at ... P35 first serves as a caspase substrate and is cleaved between the amino acids D87 and G88, i.e. after the sequence DQMD in P35 ...

Cohen GM (1997). "Caspases: the executioners of apoptosis". Biochem. J. 326 (Pt 1): 1-16. doi:10.1042/bj3260001. PMC 1218630. ... Chua BT, Guo K, Li P (2000). "Direct cleavage by the calcium-activated protease calpain can lead to inactivation of caspases". ... 275 (7): 5131-5. doi:10.1074/jbc.275.7.5131. PMID 10671558. Lee MS, Kwon YT, Li M, Peng J, Friedlander RM, Tsai LH (2000). " ...

July 2000). "Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of ... Retrieved 7 October 2022. Strauss JS, Krowchuk DP, Leyden JJ, Lucky AW, Shalita AR, Siegfried EC, et al. (April 2007). " ... Retrieved 7 August 2012. Kircik LH (November 2010). "Doxycycline and minocycline for the management of acne: a review of ... 7 (24 ed.). Eschborn, Germany: Govi Pharmazeutischer Verlag. ISBN 978-3-7741-9846-3. "Minocycline". go.drugbank.com. British ...

... similarly induce apoptosis in T lymphocytes via a caspase-dependent mitochondrial pathway". J. Immunol. 172 (7): 4008-17. doi: ... 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. Chu F, Barkinge J, Hawkins S, et al. (2005). "Expression ...

Selvakumar P, Sharma RK (2007). "Role of calpain and caspase system in the regulation of N-myristoyltransferase in human colon ... NMT2 has been shown to interact with: caspase 3 MARCKS N-myristoyltransferase 1 GRCh38: Ensembl release 89: ENSG00000152465 - ... 19 (5): 823-7. doi:10.3892/ijmm.19.5.823. PMID 17390089. Selvakumar P, Lakshmikuttyamma A, Sharma RK (2009). "Biochemical ...

Gonzalez D, Bejarano I, Barriga C, Rodriguez AB, Pariente JA (2010). "Oxidative Stress-Induced Caspases are Regulated in Human ... The reaction with borax leads to sodium perborate, a bleach used in laundry detergents: Na 2 B 4 O 7 + 4 H 2 O 2 + 2 NaOH ⟶ 2 ... Retrieved 7 July 2007. Gibbs KB (14 November 2016). "How to remove blood stains from clothes and furniture". Today.com. ... 2021 Aug 7;50(15):8355-8360. doi: 10.1039/d1cs00044f. Epub 2021 Jun 15. PMID: 34128512; PMCID: PMC8328964 Giorgio M, Trinei M, ...

Lee SH, Stehlik C, Reed JC (2001). "Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation ... Inohara N, del Peso L, Koseki T, Chen S, Nunez G (Jun 1998). "RICK, a novel protein kinase containing a caspase recruitment ... The encoded protein contains a C-terminal caspase recruitment domain (CARD), and is a component of signaling complexes in both ... 1999). "Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB". J. Biol. Chem. 274 (21): 14560-7. doi:10.1074/ ...

... induces apoptosis of human esophageal carcinoma cells through a p53/Bax/cytochrome c/caspase-9-dependent pathway" (PDF). ... 24 (7): 690-8. doi:10.1097/CAD.0b013e328362469f. PMID 23652278. S2CID 6028415. Archived from the original (PDF) on 2019-03-08. ... 230 (7): 1661-1676. doi:10.1002/jcp.24919. PMC 4402027. PMID 25546329. Collier, MA; Gallovic, MD; Peine, KJ; Duong, AD; ... Since the median lethal dose (LD50), in vitro, against macrophages is ~7 μM and near its effective concentration (EC50) ...

DRB1*04:06: caspase-8 autoantibodies silicosis-systemic sclerosis (SSc)-systemic lupus erythematosus (SLE). DRB1*04:09: T. ... Ueki A, Isozaki Y, Kusaka M (2005). "Anti-caspase-8 autoantibody response in silicosis patients is associated with HLA-DRB1, ... 47 (1): 61-7. doi:10.1539/joh.47.61. PMID 15703453. García Borrás S, Diez C, Cotorruelo C, et al. (2006). "HLA class II DRB1 ... 16 (4): 363-7. PMID 16935791. Laroni A, Calabrese M, Perini P, Albergoni M, Ranzato F, Tiberio M, Battistin L, Gallo P (2006 ...

"Relationship between Caspase Activity and Apoptotic Markers in Human Sperm in Response to Hydrogen Peroxide and Progesterone". ... 3 (1): 1-7. Lozano GM, Bejarano I, Espino J, González D, Ortiz A, García JF, Rodríguez AB, Pariente JA (2009). " ...

... the role of cannabinoid receptors and the caspase cascade in the NG 108-15 cell line". Toxicology Letters. 207 (1): 12-7. doi: ...

During apoptosis, this protein is cleaved in a caspase-dependent way. Cleavage occurs at the SALD site, resulting in a loss of ... by caspase-3 occurs at a noncanonical cleavage site". J. Biol. Chem. 275 (7): 5031-6. doi:10.1074/jbc.275.7.5031. PMID 10671544 ... 3 (7): 661-9. doi:10.1038/76615. hdl:1842/742. PMID 10862698. S2CID 14392630. Taniura H, Yoshikawa K (2002). "Necdin interacts ... 7): 2655-64. doi:10.1002/j.1460-2075.1992.tb05331.x. PMC 556741. PMID 1628625. Barel M, Balbo M, Gauffre A, Frade R (1995). " ...

The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. ... Tang D, Gururajan R, Kidd VJ (1998). "Phosphorylation of PITSLRE p110 isoforms accompanies their processing by caspases during ... 272 (18): 11694-7. doi:10.1074/jbc.272.18.11694. PMID 9115219. Loyer P, Trembley JH, Lahti JM, Kidd VJ (1998). "The RNP protein ... 273 (26): 16601-7. doi:10.1074/jbc.273.26.16601. PMID 9632733. Gururajan R, Lahti JM, Grenet J, et al. (1998). "Duplication of ...

Wang M, Qanungo S, Crow MT, Watanabe M, Nieminen AL (2005). "Apoptosis repressor with caspase recruitment domain (ARC) is ... NOL3 has been shown to interact with SFRS9 and Caspase 8. GRCh38: Ensembl release 89: ENSG00000140939 - Ensembl, May 2017 ... Ekhterae D, Platoshyn O, Zhang S, Remillard CV, Yuan JX (2003). "Apoptosis repressor with caspase domain inhibits cardiomyocyte ... "Apoptosis repressor with caspase recruitment domain (ARC) is expressed in cancer cells and localizes to nuclei". FEBS Lett. 579 ...

Caspase recruitment domain-containing protein 11 also known as CARD-containing MAGUK protein 1 (Carma 1) is a protein in the ... "Entrez Gene: CARD11 caspase recruitment domain family, member 11". Holliday MJ, Witt A, Rodriguez Gama A, Walters B, Arthur C, ... This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated ... "Card10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and ...

Furthermore, the study showed midiv-1 was capable to preventing the activation of caspase 3 by reversing the release of ... Breckenridge DG, Stojanovic M, Marcellus RC, Shore GC (March 2003). "Caspase cleavage product of BAP31 induces mitochondrial ... 9 (7): 505-18. doi:10.1038/nrn2417. PMC 2711514. PMID 18568013. Xu S, Wang P, Zhang H, Gong G, Gutierrez Cortes N, Zhu W, Yoon ... 325 (5942): 874-7. doi:10.1126/science.1176921. PMC 6546417. PMID 19679814. Otera H, Wang C, Cleland MM, Setoguchi K, Yokota S ...

In terms of mechanism, pyroptosis is activated by inflammatory caspases, including caspase-1/4/5 in humans and caspase-11 in ... caspase-1/4/5 in humans and caspase-11 in mice. These caspases contribute to the maturation and activation of the pro- ... of gram-negative bacteria directly onto caspase-4/5 in humans and caspase-11 in murines. Binding of LPS onto these caspases ... Caspase-3, an executioner caspase in apoptosis, can cleave gasdermin E (GSDME) to produce a N-terminal fragment and a C- ...