Lauber, K; Bohn, E; Kröber, SM; Xiao, Y (2003). "Apoptotic Cells Induce Migration of Phagocytes via Caspase-3-Mediated Release ... 36 (6): 1090-100. doi:10.1161/ATVBAHA.115.306964. PMC 4882253. PMID 27127201. Li X, Shao Y, Fang P, et al. (March 2018). "IL-35 ... 113 (6): 717-730. doi:10.1016/S0092-8674(03)00422-7. PMID 12809603. S2CID 17619382. Munder, PG; Modolell M; Andreesen R; ...

The NLRP1 protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to ... responsible for the recruitment and activation of pro-caspase-1 in the active form of caspase-1. Human NLRP1 activation can be ... NLRP1 has been shown to interact with caspase 9 and APAF1. Via its FIIND domain, NLRP1 interacts directly with DPP9 and DPP8 ... Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The ...

2007). "Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-κB pathway". EMBO J. 26 ( ... Tinel A, Tschopp J (2004). "The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic ... Vakifahmetoglu H, Olsson M, Orrenius S, Zhivotovsky B (2006). "Functional connection between p53 and caspase-2 is essential for ... and caspase 2. GRCh38: Ensembl release 89: ENSG00000177595 - Ensembl, May 2017 GRCm38: Ensembl release 89: ENSMUSG00000025507 ...

"Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment". Cell. 94 (2 ... "Identification of a caspase-2 isoform that behaves as an endogenous inhibitor of the caspase cascade". Cancer Res. 60 (24): ... "Identification of a caspase-2 isoform that behaves as an endogenous inhibitor of the caspase cascade". Cancer Res. 60 (24): ... Chaudhary PM, Eby MT, Jasmin A, Kumar A, Liu L, Hood L (2000). "Activation of the NF-kappaB pathway by caspase 8 and its ...

"Down-regulation of human RNA/DNA helicase SUV3 induces apoptosis by a caspase- and AIF-dependent pathway". Biology of the Cell ... 12 (6): 224. doi:10.1186/gb-2011-12-6-224. PMC 3218837. PMID 21722353. Glatt H (December 2000). "Sulfotransferases in the ... 99 (6): 323-32. doi:10.1042/BC20060108. PMID 17352692. S2CID 174431. Overview of all the structural information available in ...

"Involvement of anion exchanger-2 in apoptosis of endothelial cells induced by high glucose through an mPTP-ROS-Caspase-3 ... 15 (6): 693-704. doi:10.1007/s10495-010-0477-9. PMID 20180022. S2CID 25917589. Zhang Q, Jian L, Yao D, Rao B, Xia Y, Hu K, et ... 5 (6): 1205-1214. doi:10.1002/j.1460-2075.1986.tb04348.x. PMC 1166929. PMID 3015590. Palumbo AP, Isobe M, Huebner K, Shane S, ... 6 (9): 791-806. doi:10.1101/gr.6.9.791. PMID 8889548. Medina JF, Acín A, Prieto J (January 1997). "Molecular cloning and ...

Caspase recruitment domain-containing protein 9 is an adaptor protein of the CARD-CC protein family, which in humans is encoded ... "Entrez Gene: CARD9 caspase recruitment domain family, member 9". Bertin J, Guo Y, Wang L, Srinivasula SM, Jacobson MD, Poyet JL ... CARD9 is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated ... Merriam S, Du MQ, Dyer MJ, Robison KE, DiStefano PS, Alnemri ES (December 2000). "CARD9 is a novel caspase recruitment domain- ...

Wang KK (Jan 2000). "Calpain and caspase: can you tell the difference?". Trends in Neurosciences. 23 (1): 20-26. doi:10.1016/ ... Villa PG, Henzel WJ, Sensenbrenner M, Henderson CE, Pettmann B (Mar 1998). "Calpain inhibitors, but not caspase inhibitors, ... 111 (Pt 6): 713-722. doi:10.1242/jcs.111.6.713. PMID 9472000. Huot J, Houle F, Rousseau S, Deschesnes RG, Shah GM, Landry J ( ... 10 (6): 549-556. doi:10.1016/j.pbi.2007.08.012. PMID 17936064. Kovar DR, Staiger CJ, Weaver EA, McCurdy DW (Dec 2000). "AtFim1 ...

In contrast with IL-1, processing by caspases, like caspase-1, results in IL-33 inactivation. IL-33 is a dual function cytokine ... the IL-1β precursor has to be cleaved by a cysteine protease called caspase-1. Caspase-1 needs to be activated by a formation ... IL-18 is also synthesized as a precursor which is cleaved by caspase-1. There are indications that IL-1, not least IL-1beta, is ... April 2002). "Interleukin-1F7B (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but ...

Lamas and co-workers showed that mice with dysbiotic microbiota due to their lack of the caspase recruitment domain 9 (CARD9) ... 6-Formylindolo[3,2-b]carbazole (FICZ) is a chemical compound with the molecular formula C19H12N2O. It is a nitrogen heterocycle ... 284 (5): 2690-6. doi:10.1074/jbc.M808321200. PMID 19054769. S2CID 39681889. Fritsche, E; Schäfer, C; Calles, C; Bernsmann, T; ... 23 (6): 716-724. doi:10.1016/j.chom.2018.05.003. ISSN 1934-6069. PMID 29902437. Janosik, Tomasz; Rannug, Agneta; Rannug, Ulf; ...

"The capsid proteins of Aleutian mink disease virus activate caspases and are specifically cleaved during infection". Journal of ... 84 (6): 2687-96. doi:10.1128/JVI.01917-09. PMC 2826067. PMID 20042496. Li L, Pesavento PA, Woods L, Clifford DL, Luff J, Wang C ... 6: 1119. doi:10.3389/fmicb.2015.01119. PMC 4600916. PMID 26528267. Canuti M, Doyle HE, P Britton A, Lang AS (May 2017). "Full ... 6 (5): e30. doi:10.1038/emi.2017.13. PMC 5520478. PMID 28487558. Aleutian+Mink+Disease at the U.S. National Library of Medicine ...

Codogno P (June 2006). "Autophagy and caspase-independent cell death: p19ARF enters the game". Dev. Cell. 10 (6): 688-9. doi: ... May 2006). "A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death". Mol. Cell. 22 (4): 463- ... The half-life of ARF is about 6 hours, while the half-life of smARF is less than 1 hour. Both isoforms are degraded in the ... Cell 1998, 92(6):725-34. Bertwistle D, Sherr CJ (January 2007). "Regulation of the Arf tumor suppressor in Emicro-Myc ...

Initiator caspases: responsible for the activation of effector caspases. These caspases are activated through oligomerization ... FLIPL's pseudo-caspase has two tandem DEDs that are very similar to the N-terminus of capase-8, but in which there is an ... Studying caspases is important since they don't only control apoptosis but also inhibit it, depending on the necessity of the ... This type of apoptosis depends on the pDED of the HIP-1, and it consists in the activation of caspase-3, an enzyme that is ...

These include: Caspase inhibitors: These are primarily used and studied for their anti apoptotic effects. Trophic factors: The ... property of human alpha-synuclein in neuronal cell lines is associated with the inhibition of caspase-3 but not caspase-9 ... 26 (4-6): 901-913. doi:10.1007/s10571-006-9064-6. PMID 16897369. S2CID 6059884. Heneka MT, Carson MJ, El Khoury J, Landreth GE ... 6: 340. doi:10.3389/fnagi.2014.00340. PMC 4288130. PMID 25620929. Xu K, Xu YH, Chen JF, Schwarzschild MA (May 2010). " ...

Tang D, Lahti JM, Kidd VJ (2000). "Caspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3- ... Paroni G, Henderson C, Schneider C, Brancolini C (2001). "Caspase-2-induced apoptosis is dependent on caspase-9, but its ... mediated activation of caspase-9 via cytochrome-c release has been shown to result in the activation of caspase-8 and Bid ... "Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6- ...

... is an alias for caspase-8). They elucidated the molecular mechanisms of caspase-8's involvement in cell death processes and in ... In 2000 he with 9 co-workers published their discovery "that, similar to apoptosis, caspase-independent cell death (necroptosis ... caspase-8-independent cell death pathway using the kinase RIP as effector molecule". Nature Immunology. 1 (6): 489-495. doi: ... "viral and mammalian forms of the caspase-8-related protein FLIP" (FLICE-Like Inhibitory Protein, where "FLICE" ...

Acid Exhibits Anti-Tumor Activity on T-Cell Lymphomas In Vitro and In Vivo by Down-Regulating p-AKT and Activating Caspase-3". ... 89 (6): 1845-1853. doi:10.1182/blood.V89.6.1845. PMID 9058703. Klein R. A.; Halliday D. & Pittet P. G. (1980). "The use of 13- ... 8 (6): e65308. Bibcode:2013PLoSO...865308C. doi:10.1371/journal.pone.0065308. PMC 3676434. PMID 23762338. Kim AH; Khursigara G ...

... antagonizes both the precursor and mature forms of Smac and caspase-9". J. Biol. Chem. 280 (1): 174-82. doi:10.1074/jbc. ... "Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function". Nat. Cell Biol. 6 (9): 849-60. doi: ... 14 (6): 801-11. doi:10.1016/j.molcel.2004.05.018. PMID 15200957. Hao Y, Sekine K, Kawabata A, Nakamura H, Ishioka T, Ohata H, ... 6 (9): 791-806. doi:10.1101/gr.6.9.791. PMID 8889548. Nagase T, Ishikawa K, Kikuno R, Hirosawa M, Nomura N, Ohara O (2000). " ...

2000). "Caspase-2 Is Localized at the Golgi Complex and Cleaves Golgin-160 during Apoptosis". J. Cell Biol. 149 (3): 603-12. ... Maag RS, Mancini M, Rosen A, Machamer CE (Jun 2005). "Caspase-resistant Golgin-160 Disrupts Apoptosis Induced by Secretory ... Sbodio JI, Hicks SW, Simon D, Machamer CE (2006). "GCP60 preferentially interacts with a caspase-generated golgin-160 fragment ... 6 (9): 791-806. doi:10.1101/gr.6.9.791. PMID 8889548. Misumi Y, Sohda M, Yano A, et al. (1997). "Molecular characterization of ...

"Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis". Proceedings of ... 25 (6): 2273-2287. doi:10.1128/MCB.25.6.2273-2287.2005. PMC 1061617. PMID 15743823. Prima V, Gore L, Caires A, Boomer T, ... 99 (6): 3974-3979. Bibcode:2002PNAS...99.3974O. doi:10.1073/pnas.022036399. PMC 122633. PMID 11904443. Park SY, Shin HM, Han TH ...

July 2000). "Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of ... 18 (6): 712-719. doi:10.1097/01.wco.0000187248.21103.c5. PMID 16280684. S2CID 3255995. Amin AR, Attur MG, Thakker GD, Patel PD ... 27 (6): 293-298. doi:10.1097/01.wnf.0000150867.98887.3e. PMID 15613934. S2CID 30431947. Maier K, Merkler D, Gerber J, Taheri N ... 64 (6): 602-609. doi:10.1016/j.phrs.2011.04.001. PMID 21501686. Greenwald RA (December 2011). "The road forward: the scientific ...

Gurcel, Laure; Abrami, Laurence; Girardin, Stephen; Tschopp, Jurg; Van Der Goot, F. Gisou (2006). "Caspase-1 Activation of ... 6 (2): 137-149. doi:10.1016/j.chom.2009.07.005. PMID 19683680. Gisou van der Goot is married to Swiss biologist Jean Gruenberg ... 126 (6): 1135-1145. doi:10.1016/j.cell.2006.07.033. PMID 16990137. S2CID 616037. Pizarro-Cerdá, Javier; MéResse, StéPhane; ...

Costanzo A, Guiet C, Vito P (1999). "c-E10 is a caspase-recruiting domain-containing protein that interacts with components of ... 7 (6): 821-30. doi:10.1016/S1074-7613(00)80400-8. PMID 9430227. Schneider P, Thome M, Burns K, et al. (1998). "TRAIL receptors ... 7 (6): 831-6. doi:10.1016/S1074-7613(00)80401-X. PMID 9430228. Diab BY, Lambert NC, L'Faqihi FE, et al. (1999). "Human collagen ... 2 (6): 493-500. doi:10.1038/88684. PMID 11376335. S2CID 6923467. Trauzold A, Wermann H, Arlt A, et al. (2001). "CD95 and TRAIL ...

Possible link with the reduction in chondrocyte apoptosis and caspase 3 level". Arthritis & Rheumatism. 43 (6): 1290-1299. doi: ... 132 (6): 1735S-1739S. doi:10.1093/jn/132.6.1735s. PMID 12042511. Laflamme, D. P. (2005). "Nutrition for aging cats and dogs and ... 94 (6): e251-e258. doi:10.1111/j.1439-0396.2009.00964.x. PMID 20455969. Salas, A.; Manuelian, C.-L.; et al. (2014). "Fat ... 214 (6): 1039-1051. doi:10.1242/jeb.049429. ISSN 0022-0949. PMID 21346132. Hewson-Hughes, A. K.; Colyer, A.; et al. (2016-06-01 ...

Wang M, Qanungo S, Crow MT, Watanabe M, Nieminen AL (2005). "Apoptosis repressor with caspase recruitment domain (ARC) is ... NOL3 has been shown to interact with SFRS9 and Caspase 8. GRCh38: Ensembl release 89: ENSG00000140939 - Ensembl, May 2017 ... Ekhterae D, Platoshyn O, Zhang S, Remillard CV, Yuan JX (2003). "Apoptosis repressor with caspase domain inhibits cardiomyocyte ... "Apoptosis repressor with caspase recruitment domain (ARC) is expressed in cancer cells and localizes to nuclei". FEBS Lett. 579 ...

"Relationship between Caspase Activity and Apoptotic Markers in Human Sperm in Response to Hydrogen Peroxide and Progesterone". ... 52 (6): 252-8. doi:10.1016/S0753-3322(98)80010-3. PMID 9755824. Li X, Darzynkiewicz Z (1995). "Labeling DNA strand breaks with ... 55 (6): 615-621. doi:10.1262/jrd.20250. PMID 19734695. Gorczyca W, Bruno S, Darzynkiewicz RJ, Gong J, Darzynkiewicz Z (1992). " ... 1 (6): 639-648. doi:10.3892/ijo.1.6.639. PMID 21584593. Gavrieli Y, Sherman Y, Ben-Sasson SA (1992). "Identification of ...

Kitagawa K, Niikura Y (Apr 2008). "Caspase-independent mitotic death (CIMD)". Cell Cycle. 7 (8): 1001-5. doi:10.4161/cc.7.8. ... 153 (6): 1239-50. doi:10.1083/jcb.153.6.1239. PMC 2192030. PMID 11402067. Johnson VL, Scott MI, Holt SV, Hussein D, Taylor SS ( ... 6 (13): 1579-85. doi:10.4161/cc.6.13.4442. PMID 17617734. Boyarchuk Y, Salic A, Dasso M, Arnaoutov A (Mar 2007). "Bub1 is ... 282 (6): 3672-9. doi:10.1074/jbc.M609376200. PMID 17158872. Sharp-Baker H, Chen RH (Jun 2001). "Spindle checkpoint protein Bub1 ...

Apr 2002). "A caspase-related protease regulates apoptosis in yeast". Molecular Cell. 9 (4): 911-7. doi:10.1016/S1097-2765(02) ... In an analogous manner to caspases, metacaspases induce programmed cell death in both plants and fungi (yeast). Uren AG, ... Khan MA, Chock PB, Stadtman ER (Nov 2005). "Knockout of caspase-like gene, YCA1, abrogates apoptosis and elevates oxidized ... Metacaspases are members of the C14 class of cysteine proteases and thus related to caspases, orthocaspases and paracaspases. ...

... s are more similar to caspases than metacaspases are, indicating that this group of proteases diverged from caspases ... The "type 2" paracaspases in animals represent the ancestral form which only consists of a caspase-like domain. This form of ... The Proteolysis Map MALT1 Caspase Metacaspase MALT lymphoma Minina EA, Staal J, Alvarez VE, Berges JA, Berman-Frank I, Beyaert ... Most non-metazoan paracaspases found in amoebas or bacteria are "type 2" paracaspases with only a caspase-like domain. The ...

... caspase-11 (caspase-4 in humans), which is responsible for many of the effects previously attributed to caspase-1, including ... The 2011 paper showed that mice lacking the gene that encodes caspase-1 also carry a mutation in a neighboring caspase gene, ... They showed that these mechanisms did not depend on TLR4, but were rather mediated by caspase-11. This was significant, because ... By 2002, Dixit was among the first scientists to demonstrate that pro-inflammatory caspases are part of a molecular complex ...