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*  Casein kinase 2
Xu X, Toselli PA, Russell LD, Seldin DC (1999). "Globozoospermia in mice lacking the casein kinase II alpha' catalytic subunit ... CSNK2A1 CSNK2A2 Casein kinase 1 - a distinct protein kinase family Ahmad KA, Wang G, Unger G, Slaton J, Ahmed K (2008). " ... Casein kinase 2 (EC 2.7.11.1)(CK2/CSNK2) is a serine/threonine-selective protein kinase that has been implicated in cell cycle ... Casein kinase 2 activity has been reported to be activated following Wnt signaling pathway activation. A Pertussis toxin- ...
*  Casein kinase 2, alpha 1
Casein kinase II subunit alpha is an enzyme that in humans is encoded by the CSNK2A1 gene. Casein kinase II is a serine/ ... "Mapping of the human casein kinase II catalytic subunit genes: two loci carrying the homologous sequences for the alpha subunit ... Yamaguchi Y, Wada T, Suzuki F, Takagi T, Hasegawa J, Handa H (August 1998). "Casein kinase II interacts with the bZIP domains ... Three transcript variants encoding two different proteins have been found for this gene. Casein kinase 2, alpha 1 has been ...
*  EEF1B2
Phosphorylation by casein kinase II". Biochimica et Biophysica Acta. 1264 (3): 303-11. doi:10.1016/0167-4781(95)00166-2. PMID ... Sheu GT, Traugh JA (Jan 1999). "A structural model for elongation factor 1 (EF-1) and phosphorylation by protein kinase CKII". ... Subunit interactions, elongation activity, and phosphorylation by protein kinase CKII". The Journal of Biological Chemistry. ... "Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes". ...
*  Progesterone receptor
In vitro phosphorylation by casein kinase II". The Journal of Biological Chemistry. 269 (49): 31034-40. PMID 7983041. Mansour I ... "Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone ... "Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone ... In humans, PR is encoded by a single PGR gene residing on chromosome 11q22, it has two main forms, PR-A and PR-B, that differ ...
*  BRCA1
O'Brien KA, Lemke SJ, Cocke KS, Rao RN, Beckmann RP (July 1999). "Casein kinase 2 binds to and phosphorylates BRCA1". Biochem. ... two quartets of cysteine or histidine residues that coordinate two zinc atoms. This motif contains a short anti-parallel beta- ... "BRCA1 interacts with and is required for paclitaxel-induced activation of mitogen-activated protein kinase kinase kinase 3". ... kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment ...
*  Myc
Lüscher B, Kuenzel EA, Krebs EG, Eisenman RN (April 1989). "Myc oncoproteins are phosphorylated by casein kinase II". The EMBO ... "Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase". Proceedings of the National ... Gupta S, Davis RJ (October 1994). "MAP kinase binds to the NH2-terminal activation domain of c-Myc". FEBS Letters. 353 (3): 281 ... Iijima S, Teraoka H, Date T, Tsukada K (June 1992). "DNA-activated protein kinase in Raji Burkitt's lymphoma cells. ...
*  Thymosin α1
1992). "Prothymosin alpha is phosphorylated by casein kinase-2". FEBS Lett. 312 (2-3): 152-6. doi:10.1016/0014-5793(92)80924-6 ... 1992). "Prothymosin alpha enhances human and murine MHC class II surface antigen expression and messenger RNA accumulation". J ... 292 (2): 70-4. doi:10.1056/NEJM197501092920204. PMID 1078552. Garaci E, Favalli C, Pica F, et al. (September 2007). "Thymosin ... 85 (2-5): 117-22. doi:10.1016/S0960-0760(03)00207-3. PMID 12943695. Barcia MG, Castro JM, Jullien CD, et al. ( ...
*  Nucleolin
Li D, Dobrowolska G, Krebs EG (Jun 1996). "The physical association of casein kinase 2 with nucleolin". The Journal of ... Parada CA, Roeder RG (Jul 1999). "A novel RNA polymerase II-containing complex potentiates Tat-enhanced HIV-1 transcription". ... Li D, Dobrowolska G, Krebs EG (Jun 1996). "The physical association of casein kinase 2 with nucleolin". The Journal of ... Jordan P, Heid H, Kinzel V, Kübler D (Dec 1994). "Major cell surface-located protein substrates of an ecto-protein kinase are ...
*  Gap-43 protein
Apel ED, Litchfield DW, Clark RH, Krebs EG, Storm DR (Jun 1991). "Phosphorylation of neuromodulin (GAP-43) by casein kinase II ... It is a major protein kinase C (PKC) substrate and is considered to play a key role in neurite formation, regeneration, and ... Chao S, Benowitz LI, Krainc D, Irwin N (Sep 1996). "Use of a two-hybrid system to investigate molecular interactions of GAP-43 ... However, F1 was not cAMP kinase dependent. B-50 was regulated by the pituitary peptide ACTH and was associated with grooming ...
*  ARR3
Kim YM, Barak LS, Caron MG, Benovic JL (2002). "Regulation of arrestin-3 phosphorylation by casein kinase II". J. Biol. Chem. ... 224 (1-2): 87-95. doi:10.1016/S0378-1119(98)00510-1. PMID 9931451. John SK, Smith JE, Aguirre GD, Milam AH (2000). "Loss of ... 204 (1-2): 127-40. doi:10.1016/S0303-7207(03)00088-1. PMID 12850288. Zhu X, Brown B, Li A, et al. (2003). "GRK1-dependent ... 382 (1-2): 105-10. doi:10.1016/0014-5793(96)00163-9. PMID 8612728. ter Haar E, Musacchio A, Harrison SC, Kirchhausen T (1998 ...
*  AP3B1
Kim YM, Barak LS, Caron MG, Benovic JL (May 2002). "Regulation of arrestin-3 phosphorylation by casein kinase II". The Journal ... Dubois T, Howell S, Zemlickova E, Aitken A (Apr 2002). "Identification of casein kinase Ialpha interacting protein partners". ... 15 (2): 575-87. doi:10.1091/mbc.E03-06-0401. PMC 329249 . PMID 14657250. Guinn BA, Bland EA, Lodi U, Liggins AP, Tobal K, ... 8 (2): 323-30. doi:10.1093/hmg/8.2.323. PMID 9931340. Dell'Angelica EC, Shotelersuk V, Aguilar RC, Gahl WA, Bonifacino JS (Jan ...
*  DNA damage-inducible transcript 3
Ubeda M, Habener JF (October 2003). "CHOP transcription factor phosphorylation by casein kinase 2 inhibits transcriptional ... by p38 MAP Kinase". Science. 272 (5266): 1347-9. doi:10.1126/science.272.5266.1347. PMID 8650547. Fawcett TW, Eastman HB, ... lack of mediation by protein kinase C". Mol Cell Biol. 11 (2): 1009-16. PMC 359769 . PMID 1990262. "Entrez Gene: DDIT3 DNA- ... 4 (2): 175-80. doi:10.1038/ng0693-175. PMID 7503811. Crozat A, Aman P, Mandahl N, Ron D (1993). "Fusion of CHOP to a novel RNA- ...
*  Silmitasertib
... (INN), codenamed CX-4945, is a small-molecule inhibitor of protein kinase CK2 (casein kinase II), a ... "Casein Kinase II (CK2) as a Therapeutic Target for Hematological Malignancies". Current Pharmaceutical Design. 23 (1): 95-107. ... CS1 maint: Uses authors parameter (link) Chon HJ, Bae KJ, Lee Y, Kim J (2015). "The casein kinase 2 inhibitor, CX-4945, as an ... the first clinical stage inhibitor of protein kinase CK2 for the treatment of cancer". Journal of Medicinal Chemistry. 54 (2): ...
*  Epithelial-mesenchymal transition
"Casein Kinase II (CK2) as a Therapeutic Target for Hematological Malignancies". Current Pharmaceutical Design. 23 (1): 95-107. ... Two mathematical models have been proposed, attempting to explain the emergence of this hybrid E/M phenotype, and its highly ... Silmitasertib (CX-4945) is a small molecule inhibitor of protein kinase CK2, which has been supported to be linked with TGF-β ... The phosphatidylinositol 3' kinase (PI3K)/AKT axis, Hedgehog signaling pathway, nuclear factor-kappaB and Activating ...
*  Globozoospermia
Xu, X.; Toselli, P. A.; Russell, L. D.; Seldin, D. C. (1999-09-01). "Globozoospermia in mice lacking the casein kinase II alpha ... There are two types of globozoospermia: Type 1 globozoospermia exhibits a complete lack of acrosome and acrosomal enzymes and ... however it is unclear whether these two forms are variations on the same syndrome, or actually different syndromes. Studies ... doi:10.1007/s10815-015-0433-2. ISSN 1058-0468. PMC 4380889 . PMID 25711835. Dam, A. H. D. M.; Feenstra, I.; Westphal, J. R.; ...
*  Nucleolar phosphoprotein p130
Li D, Meier UT, Dobrowolska G, Krebs EG (1997). "Specific interaction between casein kinase 2 and the nucleolar protein Nopp140 ... Pai CY, Yeh NH (1996). "Cell proliferation-dependent expression of two isoforms of the nucleolar phosphoprotein p130". Biochem ... Chiu CM, Tsay YG, Chang CJ, Lee SC (2002). "Nopp140 is a mediator of the protein kinase A signaling pathway that activates the ... 142 (2): 319-29. doi:10.1083/jcb.142.2.319. ISSN 0021-9525. PMC 2133063 . PMID 9679133. Miau, L H; Chang C J; Shen B J; Tsai W ...
*  JADE1
... is a target of phosphorylation by Casein kinase 2 (CK2). In addition, multiple phosphorylation sites are found by high ... Two resultant protein products of the JADE1 gene were designated JADE1S for the short (which is same as(3)) and JADE1L for the ... "Casein kinase 1 α phosphorylates the Wnt regulator Jade-1 and modulates its activity". The Journal of Biological Chemistry. 289 ... There are two known protein products of the PHF17 gene, the full length JADE1 (JADE1L) and its splice variant missing the C- ...
*  Casein kinase 1, alpha 1
Zhang Y, Qiu WJ, Chan SC, Han J, He X, Lin SC (May 2002). "Casein kinase I and casein kinase II differentially regulate axin ... Casein kinase I isoform alpha is an enzyme that in humans is encoded by the CSNK1A1 gene. Casein kinase 1, alpha 1 has been ... Casein kinase 1 GRCh38: Ensembl release 89: ENSG00000113712 - Ensembl, May 2017 GRCm38: Ensembl release 89: ENSMUSG00000024576 ... Dubois T, Howell S, Zemlickova E, Aitken A (Apr 2002). "Identification of casein kinase Ialpha interacting protein partners". ...
*  Calsequestrin
Cala SE, Jones LR (January 1991). "Phosphorylation of cardiac and skeletal muscle calsequestrin isoforms by casein kinase II. ... Both forms of calsequestrin are phosphorylated by casein kinase 2, but the cardiac form is phosphorylated more rapidly and to a ... Two forms of calsequestrin have been identified. The cardiac form Calsequestrin-2 (CASQ2) is present in cardiac and slow ... In addition, the hydrophobic core of domain II appears to be necessary for CASQ2's function, because a single amino acid ...
*  STARD10
Casein kinase II phosphorylates the protein on its serine at position 184. The function of StarD10 in the cell is not yet ... "Phosphorylation of StarD10 on serine 284 by casein kinase II modulates its lipid transfer activity". The Journal of Biological ... "Phosphorylation of StarD10 on serine 284 by casein kinase II modulates its lipid transfer activity". The Journal of Biological ... 3.0.CO;2-P. PMID 9610721. "Entrez Gene: STARD10 START domain containing 10". Olayioye MA, Vehring S, Müller P, Herrmann A, ...
*  C-Fos
Yamaguchi Y, Wada T, Suzuki F, Takagi T, Hasegawa J, Handa H (August 1998). "Casein kinase II interacts with the bZIP domains ... Yang X, Chen Y, Gabuzda D (September 1999). "ERK MAP kinase links cytokine signals to activation of latent HIV-1 infection by ... Hurd TW, Culbert AA, Webster KJ, Tavaré JM (December 2002). "Dual role for mitogen-activated protein kinase (Erk) in insulin- ... Psychostimulants] increase cAMP levels in striatum, which activates protein kinase A (PKA) and leads to phosphorylation of its ...
*  LIG1
... and Ser91 by cyclin-dependent kinase (CDK) and Ser66 by casein kinase II (CKII). Phosphorylation of these residues (Ser66 in ... "Activation of mammalian DNA ligase I through phosphorylation by casein kinase II". EMBO J. 11 (8): 2925-33. PMC 556774 . PMID ... There are two families of DNA ligases, ATP-dependent DNA ligases and NAD+ dependent DNA ligases. Dependence upon ATP or NAD+ is ... "Cell cycle-dependent phosphorylation of human DNA ligase I at the cyclin-dependent kinase sites". J. Biol. Chem. 278 (39): ...
*  HNRNPA2B1
HNRPA2B1 has been shown to interact with casein kinase 2, alpha 1. The mutation p.D290V/302V in hnRNPA2B1 is implicated in ... The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to ... Bauw G, Rasmussen HH, van den Bulcke M, van Damme J, Puype M, Gesser B, Celis JE, Vandekerckhove J (1990). "Two-dimensional gel ... "Two homologous genes, originated by duplication, encode the human hnRNP proteins A2 and A1". Nucleic Acids Res. 22 (11): 1996- ...
*  Glial cell line-derived neurotrophic factor
Yamaguchi Y, Wada T, Suzuki F, Takagi T, Hasegawa J, Handa H (Aug 1998). "Casein kinase II interacts with the bZIP domains of ... In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as ... "GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF". Cell. 85 (7 ... Jing S, Yu Y, Fang M, Hu Z, Holst PL, Boone T, Delaney J, Schultz H, Zhou R, Fox GM (Dec 1997). "GFRalpha-2 and GFRalpha-3 are ...
*  CREB-binding protein
Yamaguchi Y, Wada T, Suzuki F, Takagi T, Hasegawa J, Handa H (August 1998). "Casein kinase II interacts with the bZIP domains ... Shimomura A, Ogawa Y, Kitani T, Fujisawa H, Hagiwara M (July 1996). "Calmodulin-dependent protein kinase II potentiates ... Cho H, Orphanides G, Sun X, Yang XJ, Ogryzko V, Lees E, Nakatani Y, Reinberg D (September 1998). "A human RNA polymerase II ... Lee SK, Jung SY, Kim YS, Na SY, Lee YC, Lee JW (February 2001). "Two distinct nuclear receptor-interaction domains and CREB- ...
*  Herpes simplex virus protein vmw65
... position 375 of VP16 is critical for complex assembly with Oct-1 and HCF and is a target of phosphorylation by casein kinase II ...