"Heritability of articular cartilage regeneration and its association with ear wound healing in mice". Arthritis and Rheumatism ...
Along with type-II collagen, aggrecan forms a major structural component of cartilage, particularly articular cartilage. The ... Articular cartilage contains up to 10% proteoglycan by weight, most of which is aggrecan, and its loss is an early sign of the ... Osteoarthritis is characterized by the slow progressive deterioration of articular cartilage and fibrosis of the synovium and ... "Age-related changes in the content of the C-terminal region of aggrecan in human articular cartilage". Biochem. J. 313. 313 (3 ...
"The structure of the keratan sulphate chains attached to fibromodulin from human articular cartilage". Glycoconj. J. 14 (5): ... The amount of KS found in the cornea is 10 fold higher than it is in cartilage and 2-4 times higher than it is in other tissues ... Cartilage KSII is almost entirely sulphated, consisting of disulphated monomers interrupted occasionally by a single ... Meyer K; Hoffman P.; Linker A. (1958). "Mucopolysaccharides of Costal Cartilage". Science. 128 (3329): 896. Bibcode:1958Sci... ...
Articular cartilage covers the concave area of acetabulum, providing more stability and shock absorption. Surrounding the ... Although this joint has three degrees of freedom, it is still stable due to the interaction of ligaments and cartilage. The ...
Natural synthesis of glucosamine occurs in the extracellular matrix of articular cartilage in joints. However, as a result of ... Glucosamine is an amino-monosaccharide that naturally occurs in all tissues, particularly in articular cartilage of joints and ... oxidative damage and inflammatory mediators combine to induce the gradual degeneration of the articular cartilage in the joint ... have been shown to be highly effective in the prevention of cartilage catabolism in in vitro models, suggesting that its ...
The articular bone, which formed the jaw joint, was probably heavily encased in cartilage. The jaw probably moved in a ...
The joint surface of all bones in the ankle are covered with articular cartilage. The distances between the bones in the ankle ... The articular surface of the tibia may be referred to as the plafond (French for "ceiling"). The medial malleolus is a bony ...
Articular cartilage damage Articular cartilage injuries Articular cartilage repair List of distinct cell types in the adult ... Articular cartilage is hyaline cartilage on the articular surfaces of bones, and lies inside the joint cavity of synovial ... Maintenance of articular cartilage is guided by a balance of anabolic (cartilage generating) and catabolic (cartilage degrading ... Though it is often found in close contact with menisci and articular disks, articular cartilage is not considered a part of ...
It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is ... and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage". The Journal of ...
"Chondroitin sulfate sulfation motifs as putative biomarkers for isolation of articular cartilage progenitor cells". The Journal ...
Contribution of joint tissues to their articular production". Osteoarthritis and Cartilage. 14 (7): 690-695. doi:10.1016/j.joca ... Gualillo O (August 2007). "Further evidence for leptin involvement in cartilage homeostases". Osteoarthritis and Cartilage. 15 ... effect on cartilage metabolism". Osteoarthritis and Cartilage. 15 (8): 872-883. doi:10.1016/j.joca.2007.01.018. PMID 17350295. ... October 2004). "In vivo leptin expression in cartilage and bone cells of growing rats and adult humans". Journal of Anatomy. ...
It is surrounded by the articular lunate surface.: 1368 The floor of the fossa is formed mostly by the ischium; it is rough: ... The fossa does not contain any cartilage.: 1368 It is occupied by the ligament of head of femur,[better source needed] and by ... The acetabular fossa is the non-articular depressed region at the centre of the floor of the acetabulum. ...
... why these ligaments are both intracapsular and extra-articular with their tibial attachment located exactly on the cartilage ... The articular capsule of the knee joint is the wide and lax joint capsule of the knee. It is thin in front and at the side, and ... Anteriorly, the reflection of the synovial membrane lies on the femur; located at some distance from the cartilage because of ... On the tibia, the anterior reflection and attachment of the synovial membrane is located near the cartilage. Anteriorly, the ...
Proteins involved in autophagy are reduced with age in both human and mouse articular cartilage. Mechanical injury to cartilage ... Autophagy is constantly activated in normal cartilage but it is compromised with age and precedes cartilage cell death and ... Caramés B, Taniguchi N, Otsuki S, Blanco FJ, Lotz M (March 2010). "Autophagy is a protective mechanism in normal cartilage, and ... Caramés B, Olmer M, Kiosses WB, Lotz MK (June 2015). "The relationship of autophagy defects to cartilage damage during joint ...
Early on there is flattening of articular surfaces, thinning of cartilage with osteophyte (spur) formation. In juxta-articular ... The diagnosis is made by x-ray/MRI appearance and has five juxta-articular classifications and forehead, neck, and shaft ... The distribution of lesions differs with the type of exposure - the juxta-articular lesions being more common in caisson ... Divers who have suffered from DON are at increased risk of future fracture of a juxta-articular lesion during a dive, and may ...
It requires general anesthesia, but allows thorough visualization of the synovial membrane and articular cartilage. Treatment ... May be articular (osteoarthritis) or non-articular. The articular forms can affect the pastern or coffin joints, and can cause ... May be "articular windgalls," which are the result of excessive synovial fluid in the fetlock joint capsule and located on the ... Intra-articular analgesia of the DIP joint alleviates lameness associated with the navicular bursa in horses. Vet Surg 1997; 26 ...
"Oxidative changes and signaling pathways are pivotal in initiating age-related changes in articular cartilage". Annals of the ... Collagen tissues provide support for the formation of bones, tendons, and cartilage, which depends on their level of ...
Bashir, A; Gray, ML; Boutin, RD; Burstein, D (Nov 1997). "Glycosaminoglycan in articular cartilage: in vivo assessment with ... imaging of cartilage or dGEMRIC measures the fixed-charge density and relative proteoglycan content of articular cartilage ... of Glycosaminoglycans in Cartilage by MRI dGEMRIC Method Delayed Gadolinium-enhanced MR Imaging of Articular Cartilage: Three- ... Preliminary Results Glycosaminoglycan Distribution in Cartilage as Determined by Delayed Gadolinium-Enhanced MRI of Cartilage ( ...
Bashir A, Gray ML, Boutin RD, Burstein D (November 1997). "Glycosaminoglycan in articular cartilage: in vivo assessment with ... are related to the concentration of proteoglycan aggregates and charged glycosaminoglycan side chains in articular cartilage. ... Bashir A, Gray ML, Hartke J, Burstein D (May 1999). "Nondestructive imaging of human cartilage glycosaminoglycan concentration ... chelates allow delayed Gadolinium-enhanced Magnetic Resonance of Cartilage (dGEMRIC). The unique charge characteristic of this ...
Osteoarthritis and Cartilage. 11 (2): 92-101. doi:10.1053/joca.2002.0858. PMID 12554125. Otsuki T, Ota T, Nishikawa T, Hayashi ... "Molecular characterization and partial cDNA cloning of facilitative glucose transporters expressed in human articular ...
... 's effect toward the articular cartilage integrity as it is part of the proteoglycan molecules. The cartilage ...
"Mannosamine inhibits aggrecanase-mediated changes in the physical properties and biochemical composition of articular cartilage ...
In June 2009, Jordan Morgan had surgery on his left knee to repair articular cartilage. The expected recovery time was four to ...
Rosenberg L (1971). "Chemical Basis for the Histological Use of Safranin O in the Study of Articular Cartilage". J Bone Joint ... It can also be used for the detection of cartilage, mucin and mast cell granules. Safranin typically has the chemical structure ...
This cell based articular cartilage repair procedure takes place in three stages. In a first stage, between 200 and 300 ... The goal of ACI is to allow people suffering from articular cartilage damage to return to their old lifestyle; regaining ... until there are enough cells to reimplant on the damaged area of the articular cartilage. The patient then undergoes a second ... is a biomedical treatment that repairs damages in articular cartilage. ACI provides pain relief while at the same time slowing ...
The articular cartilage angle (AC angle, also called acetabular index or Hilgenreiner angle) is an angle formed parallel to the ... Both joint surfaces are covered with a strong but lubricated layer called articular hyaline cartilage. The cuplike acetabulum ... The Y-shaped growth plate that separates them, the triradiate cartilage, is fused definitively at ages 14-16. It is a special ... or a line connecting the corner of the triangular cartilage and the lateral acetabular rim. In normal hips in children aged ...
Bashir, A; Gray, M L; Boutin, R D; Burstein, D (1997-11-01). "Glycosaminoglycan in articular cartilage: in vivo assessment with ... Frequently, X-rays would be used to evaluate the condition of cartilage, but cartilage doesn't show up on an X-ray image. ... Instead, doctors judge by the distance between bones, which do appear from the X-ray, to evaluate the state of the cartilage ... Early experiments involved applying mechanical forces to cartilage tissue ex-vivo and observing the effects to cells. From ...
It makes up 50% of all protein in cartilage and 85-90% of collagen of articular cartilage. Type II collagen is organised into ... Type II collagen is the basis for hyaline cartilage, including the articular cartilages at joint surfaces. It is formed by ... This fibrillar network of collagen allows the cartilage to entrap the proteoglycan aggregate, as well as providing tensile ...
"Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS-4 and ADAMTS-5". Arthritis and Rheumatism ... Genetically modified mice in which the catalytic domain of ADAMTS5 was deleted are resistant to cartilage destruction in an ... ADAMTS5 is the major aggrecanase in mouse cartilage in a mouse model of inflammatory arthritis. GRCh38: Ensembl release 89: ... "ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro". Nature. 434 (7033): 648-52. Bibcode:2005Natur.434.. ...
The anterior medial aspect of the ligament is lined by a thin layer of articular cartilage. The neck of the odontoid process is ... "Regression of an atlantoaxial degenerative articular cyst associated with subluxation during conservative treatment. Case ...