At physiological pH, the carboxylic acid is deprotonated (−CO2−) and both the amino and guanidino groups are protonated, ... Patients with cardiovascular or gallbladder disease should be cautioned and warned of the theoretical risks." A meta-analysis ... This is an energetically costly process, because for each molecule of argininosuccinate that is synthesized, one molecule of ... Arginine's side chain is amphipathic, because at physiological pH it contains a positively charged guanidinium group, which is ...
This process of RNA editing generates 14 unique receptor isoforms of the 5-HT2C receptor that differ in three amino acids in ... This distribution pattern may explain the effect they have in integral function in the control of many physiological and ... After several reports of adverse cardiovascular effects, the FDA banned dexfenfluramine in 1997. It appears that the 5-HT2B ... The 5-HT2C receptors are the only G-protein coupled receptors known to undergo a post-transcriptional process of RNA editing. ...
... which has streamlined the process compared to using PubMed. Besides its usefulness for RGD internal curation processes, the ... As of May 2021, RGD has fifteen disease portals: Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 ... as well as Physiological Pathway diagrams which display networks of organs, tissues, cells and molecular pathways at the whole ... Pathway Suites and Suite Networks, i.e. groupings of related pathways which all contribute to a larger process such as glucose ...
... to acute stressors are associated with attenuated physiological responses to stress, including reduced cardiovascular ... As shift strategies depend more on internal processes (self-control and regulation), than external resources, it is ... Bower, Julienne E.; Kemeny, Margaret E.; Taylor, Shelley E.; Fahey, John L. (1998). "Cognitive processing, discovery of meaning ... Gutkowska, Jolanta; Jankowski, Marek (2008). "Oxytocin revisited: It is also a cardiovascular hormone". Journal of the American ...
Three physiological processes cause an increase in allostatic load: Frequent stress: the magnitude and frequency of response to ... This association explains the increased risk for cardiovascular disease and chronic conditions like obesity, diabetes, ... Homeostasis is the regulation of physiological processes, whereby systems in the body respond to the state of the body and to ... Allostatic load is not unique to humans and may be used to evaluate the physiological effects of chronic or frequent stress in ...
Cannon B, Nedergaard J (January 2004). "Brown adipose tissue: function and physiological significance". Physiological Reviews. ... Cold is a primary regulator of BAT processes and induces WAT browning. Browning in response to chronic cold exposure has been ... Dhaliwal SS, Welborn TA (May 2009). "Central obesity and multivariable cardiovascular risk as assessed by the Framingham ... Fat cells have an important physiological role in maintaining triglyceride and free fatty acid levels, as well as determining ...
... they have subtle biochemical and physiological roles in cellular processes, like vascular functions or nerve conduction. ... Kendler BS (2006). "Supplemental conditionally essential nutrients in cardiovascular disease therapy". The Journal of ... An essential nutrient is a nutrient required for normal physiological function that cannot be synthesized in the body - either ... Some nutrients can be metabolically converted to smaller molecules in the process of releasing energy, such as for ...
... which are essentially the same physiological process. (However, 'toning' implies moderate muscle definition, whereas 'building ... a decreased likelihood of contracting many cardiovascular diseases, etc. Implementing or emphasizing an increased consistent ... Diet itself helps to increase calorie burning by boosting metabolism, a process further enhanced while gaining more lean muscle ... Diet itself helps to increase calorie burning by boosting metabolism, a process further enhanced while gaining more lean muscle ...
Nascent cardiolipin has to go through a remodeling process, which involves deacylation to monolysocardiolipin (MLCL), then re- ... cardiovascular and neurodegenerative diseases, such as obesity, nonalcoholic fatty liver disease, coronary heart disease, and ... and consequently faster depletion of physiological cardiolipin due to oxidation. Moreover, the activity of ALCAT1 is up- ...
ets1 is involved in extracellular matrix (ECM) degradation which is an important process required for tumor cell invasion and ... Cardiovascular Research. 84 (3): 434-41. doi:10.1093/cvr/cvp232. PMID 19581315. Takaya T, Ono K, Kawamura T, Takanabe R, Kaichi ... Physiological Genomics. 43 (10): 621-30. doi:10.1152/physiolgenomics.00136.2010. PMC 3110887. PMID 20841498. Chen JF, Tao Y, Li ... microRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give products at ~22 ...
They offer potential for incorporating on-chip biomolecular and cell-secreted factor detection in the context of physiological ... He is also the Director, NSERC CREATE program in Microfluidic Applications and Training in Cardiovascular Health (MATCH) (2009- ... Some notable works include: "Calcific Aortic Valve Disease: Not Simply a Degenerative Process" "Dual growth factor delivery and ... From 2009 to 2014, Simmons lead the NSERC CREATE program in Microfluidics Applications and Training in Cardiovascular Health ( ...
This imposed several physiological strains on them. Macondo-252 oil may also drop within the water column and pose a new ... Fish need oxygen to survive and carry out normal activities and processes. Lower levels of oxygen is common in near-shore ... leading to underdeveloped cardiovascular systems, decreased nerve functions, decreased endocrine and hormone secretions, and ... Oil in the sedimentary layer can be transferred through endocytosis-like processes that bring the developing F. grandis embryos ...
It reduces the physiological responses to strong emotions, such as fear and laughter, diminishes the body's physical reaction ... Arousal is essential to consciousness, in regulating attention and information processing, memory and emotion. ETS patients are ... The baroreflex response for maintaining cardiovascular stability is suppressed in the patients who received the ETS. Exertional ... aberrant physiological reaction to stress and exertion, Raynaud's disease (albeit a possible indication for surgery), reflex ...
The exam process is open to a perfusion student that has graduated or about to graduate from an accredited perfusion education ... A cardiovascular perfusionist, clinical perfusionist or perfusiologist, and occasionally a cardiopulmonary bypass doctor or ... during cardiac surgery and other surgeries that require cardiopulmonary bypass to manage the patient's physiological status. As ... Upon graduating from a perfusion program, the graduate must begin the certification process. In the interim, the perfusion ...
... describes the processes which help stabilise the concentration of free calcium ions within cells, in a ... Cardiovascular Research. 104 (2): 347-54. doi:10.1093/cvr/cvu201. PMC 4240166. PMID 25183792. Eisner, David; Neher, Erwin; ... Taschenberger, Holger; Smith, Godfrey (2023-06-16). "Physiology of intracellular calcium buffering". Physiological Reviews. doi ...
P11 interacts with the serotonin receptor proteins, 5-HT receptors such as 5-HT1B, a receptor involved in the physiological ... They regulate a number of cellular processes such as cell cycle progression and differentiation. The S100 protein is implicated ... Serotonin affects diverse systems including the cardiovascular, renal, immune, and gastrointestinal systems. Current research ... Current experiments on animals have shown that various factors and physiological stimuli have been successful in regulating the ...
Lysosomal protein genes are transcribed in the nucleus in a process that is controlled by transcription factor EB (TFEB). mRNA ... Christian de Duve, at the Laboratory of Physiological Chemistry at the Catholic University of Louvain in Belgium, had been ... These genetic defects are related to several neurodegenerative disorders, cancers, cardiovascular diseases, and aging-related ... Besides degradation of polymers, the lysosome is involved in various cell processes, including secretion, plasma membrane ...
... processes. The definition reads: Biofeedback is a process that enables an individual to learn how to change physiological ... Schwartz (1971, 1972) examined whether specific patterns of cardiovascular activity are easier to learn than others due to ... A more simple definition could be: Biofeedback is the process of gaining greater awareness of many physiological functions ... This processing allows for a unified signal that is then able to be compared to other signals using the same processing ...
This same process of mitochondrial destruction through the opening of the MPT pore is implicated in making traumatic brain ... The increase in blood pressure can cause cardiovascular events; it is thus recommended that the lowest effective dose for ... However, brief mitochondrial permeability transition pore openings play an essential physiological role in maintaining healthy ... Physiological Reviews. 94 (3): 909-50. doi:10.1152/physrev.00026.2013. PMC 4101632. PMID 24987008. Borel JF (June 2002). " ...
σ1R is targeted by the nsp6 protein of SARS-CoV-2 to inhibit autophagosome formation as a process competing with the ... A variety of specific physiological functions have been attributed to the σ1 receptor. Chief among these are modulation of Ca2+ ... It has been implicated in several phenomena, including cardiovascular function, schizophrenia, clinical depression, the effects ... Autophagy is a broad homeostatic, metabolic, cytoplasmic quality control, and metabolic process affecting many functions in the ...
This process is not fully understood, but may occur out of a need to balance mechanical forces such as pressure and perfusion. ... Cardiovascular disease remains one of the most common causes of death globally and is often associated with the blockage or ... However, dilation also leads to increased blood flow through the vessel, which can result in hyperaemia, affect physiological ... The process typically begins at day 22, and continues to the tenth week of human embryogenesis. This first passage of fluid ...
... has been found having associations with many physiological systems such as cardiovascular, thermoregulation, and ... Serotonin is involved in numerous physiological processes, including sleep, thermoregulation, learning and memory, pain, ( ... Page IH (1 July 1954). "Serotonin (5-Hydroxytryptamine)". Physiological Reviews. American Physiological Society. 34 (3): 563- ... and numerous physiological processes such as vomiting and vasoconstriction. This multifacetedness has led to its study being ...
... so it is important to establish the cardiovascular and respiratory status and the physiological values of the patient to avoid ... Periodontitis is an irreversible process unless the animal is treated with advanced periodontal surgery techniques. Periodontal ...
Methemoglobinemia is a process where iron in hemoglobin is altered, reducing its oxygen-carrying capability, which produces ... April 2008). "Use of lipid emulsion in the resuscitation of a patient with prolonged cardiovascular collapse after overdose of ... risks of toxicity may be higher in pregnancy due to an increase in unbound fraction of local anesthetic and physiological ... Even levobupivacaine and ropivacaine (single-enantiomer derivatives), developed to ameliorate cardiovascular side effects, ...
Because of these physiological effects, the psychological concept of perseverative cognition helps to explain how psychological ... Cognitive perseverance not only impacts mental and physical processing, but it also has the possibility of impacting sleep, as ... Larsen, B.A; Christenfeld, N.J.S. (2009). "Cardiovascular Disease and Psychiatric Comorbidity: The Potential Role of ... Ottaviani, C.; Lonigro, A.; Medea, B.; Couyoumdjian, A.; Thayer, J.F.; Verkuil, B.; Brosschot, J.F. (2015). "Physiological ...
Studies have elucidated different roles for LRP1 in cellular processes relevant for cardiovascular disease. Atherosclerosis is ... and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological ... The LRP1 gene encodes a 600 kDa precursor protein that is processed by furin in the trans-Golgi complex, resulting in a 515 kDa ... LRP1 is also a key signalling protein and, thus, involved in various biological processes, such as lipoprotein metabolism and ...
Functionally from physiological point of view blood vessels can be divided in several categories Buffer vessels - aorta, middle ... Cardiovascular Physiology By William R. Milnor (Articles needing additional references from June 2021, All articles needing ... The regulation of arterial diameter and wall structure is a continuous process of adaptation to changing needs, ranging from ...
In physiological literature, it is given the name 20:5(n-3). It also has the trivial name timnodonic acid. In chemical ... The process is repeated to form EPA. The US National Institute of Health's MedlinePlus lists medical conditions for which EPA ( ... "Vascepa® (icosapent ethyl) 26% Reduction in Key Secondary Composite Endpoint of Cardiovascular Death, Heart Attacks and Stroke ... and cardiovascular death by 25% relative to a placebo in those with statin-resistant hypertriglyceridemia. EPA is obtained in ...
The notion that veins do not behave as rigid tubes but as eminently collapsible tubes suffering from the process of collapse in ... J.L. Duomarco; C.E. Giambruno; R. Rimini; Cardiovascular Functions Ed. A. A. Luisada McGraw Hill, New York, 1962, p. 2-307. ... According to the Science Citation Index, many of these papers are still being referenced in modern physiological research ... J.L. Duomarco; R. Rimini; "Cardiology" An Encyclopedia of the Cardiovascular System. Ed. A.A. Luisada, McGraw Hill, New York, ...
... is the culmination of a series of physiological and anatomic processes of puberty: Attainment of a sufficient body ... Some studies have shown that there may be an association between early or late-age menarche and cardiovascular disease, ... though a variety of physiological processes, including pheromones, have been suggested based on animal research. Most of these ... "Association between age at menarche and cardiovascular disease: A systematic review on risk and potential mechanisms". ...