*  MYH7
Alpert NR, Brosseau C, Federico A, Krenz M, Robbins J, Warshaw DM (Oct 2002). "Molecular mechanics of mouse cardiac myosin ... MHC-β is the major protein comprising the thick filament in cardiac muscle and plays a major role in cardiac muscle contraction ... Approximately 300 myosin molecules constitute one thick filament. There are two isoforms of cardiac MHC, α and β, which display ... A beta cardiac myosin heavy chain gene missense mutation". Cell. 62 (5): 999-1006. doi:10.1016/0092-8674(90)90274-i. PMID ...
*  ACTC1
Cardiac alpha actin is a 42.0 kDa protein composed of 377 amino acids. Cardiac alpha actin is a filamentous protein extending ... Myosin binding increases the flexibility of actin, and cross-linking studies have shown that myosin subfragment-1 binds to ... Alpha cardiac actin is the major protein of the thin filament in cardiac sarcomeres, which are responsible for muscle ... ACTC1 encodes cardiac muscle alpha actin. This isoform differs from the alpha actin that is expressed in skeletal muscle, ACTA1 ...
*  Hypertrophic cardiomyopathy
The cardiac myosin binding protein C mutation identified in Maine Coon cats has not been found in any other breed of cat with ... The first genetic mutation (in cardiac myosin binding protein C) responsible for feline HCM was discovered in 2005 in Maine ... It fails to acknowledge the age at which relatives suffered sudden cardiac death, as well as the frequency of the cardiac ... While there is use of echocardiography, cardiac catheterization, or cardiac MRI in the diagnosis of the disease, other ...
*  Myosin binding protein C, cardiac
"Dissecting the N-terminal myosin binding site of human cardiac myosin-binding protein C. Structure and myosin binding of domain ... "Protein Information - Myosin-binding protein C, cardiac-type". Cardiac Organellar Protein Atlas Knowledgebase (COPaKB). NHLBI ... "Double heterozygosity for mutations in the beta-myosin heavy chain and in the cardiac myosin binding protein C genes in a ... "A molecular screening strategy based on beta-myosin heavy chain, cardiac myosin binding protein C and troponin T genes in ...
*  TEAD1
Gupta MP, Gupta M, Dizon E, Zak R (1996). "Sympathetic control of cardiac myosin heavy chain gene expression". Molecular and ... This recruitment leads to the repression of the MLC2v (Myosin Light Chain 2 v) and βMHC ( β-myosin heavy chain ) promoter. ... Regulation of myosin heavy chain genes, cardiac muscular genes troponin T and I Regulation of proliferation, Regulation of ... for positive regulation of cardiac alpha-myosin heavy-chain gene expression". Molecular and Cellular Biology. 17 (7): 3924-36. ...
*  Para-Nitroblebbistatin
"Modulating Beta-Cardiac Myosin Function at the Molecular and Tissue Levels". Frontiers in Physiology. 7: 659. doi:10.3389/fphys ... para-Nitroblebbistatin is a non-phototoxic, photostable myosin inhibitor with low fluorescence. Its myosin inhibitory ... "Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells". Nature Communications. ... para-Nitroblebbistatin has been successfully used in fluorescent imaging experiments involving myosin IIA-GFP expressing live ...
*  Brian Morris (biologist)
He also cloned the first cardiac myosin heavy chain gene. He and his team were the first to elucidated the biosynthetic pathway ...
*  Katarína Horáková
"Peroxidase labelled monoclonal antibody against light chains of human cardiac myosin". General physiology and biophysics. 10 (1 ...
*  Neuregulin 1
Downstream effectors of NRG-1/ErbB, include cardiac-specific myosin light chain kinase (cMLCK), Protein Phosphatase type 1 (PP1 ... "A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart". J. Clin. Invest. 117 (10): 2812-24. ... "Identification of cardiac-specific myosin light chain kinase". Circ. Res. 102 (5): 571-80. doi:10.1161/CIRCRESAHA.107.161687. ... Bassani JW, Yuan W, Bers DM (May 1995). "Fractional SR Ca release is regulated by trigger Ca and SR Ca content in cardiac ...
*  MYLK3
Phosphorylation of cardiac myosin heavy chains (see MYH7B) and light chains (see MYL2) by a kinase, such as MYLK3, potentiates ... 2007). "A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart". J. Clin. Invest. 117 (10): ... "A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart". J. Clin. Invest. 117 (10): 2812-24. ... "Identification of cardiac-specific myosin light chain kinase". Circ. Res. 102 (5): 571-80. doi:10.1161/CIRCRESAHA.107.161687. ...
*  MYLK
2007). "A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart". J. Clin. Invest. 117 (10): ... This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce ... Myosin light chain kinase, smooth muscle also known as kinase-related protein (KRP) or telokin is an enzyme that in humans is ... "Entrez Gene: MYLK myosin, light chain kinase". Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial ...
*  UC Davis School of Veterinary Medicine
1987 Aug 14;237(4816):764-8. A cardiac myosin binding protein C mutation in the Maine Coon cat with familial hypertrophic ...
*  MYH6
"Complete sequence of human cardiac alpha-myosin heavy chain gene and amino acid comparison to other myosins based on structural ... Matsuoka R, Yoshida MC, Kanda N, Kimura M, Ozasa H, Takao A (Feb 1989). "Human cardiac myosin heavy chain gene mapped within ... Saez LJ, Gianola KM, McNally EM, Feghali R, Eddy R, Shows TB, Leinwand LA (Jul 1987). "Human cardiac myosin heavy chain genes ... Epp TA, Dixon IM, Wang HY, Sole MJ, Liew CC (Dec 1993). "Structural organization of the human cardiac alpha-myosin heavy chain ...
*  Lalji Singh
2009). "A common MYBPC3 (cardiac myosin binding protein C) variant associated with cardiomyopathies in South Asia". Nature ...
*  List of autoimmune diseases
"Mimicry in recognition of cardiac myosin peptides by heart-intralesional T cell clones from rheumatic heart disease". Journal ... Blauwet, Lori A.; Cooper, Leslie T. (31 October 2012). "Idiopathic giant cell myocarditis and cardiac sarcoidosis". Heart ...
*  Rheumatic fever
May 2006). "Mimicry in recognition of cardiac myosin peptides by heart-intralesional T cell clones from rheumatic heart disease ... Association with Cardiac Failure". The New England Journal of Medicine. 271 (13): 637-45. doi:10.1056/NEJM196409242711301. PMID ... The antibodies which the immune system generates against the M protein may cross-react with heart muscle cell protein myosin, ... The use of antibiotics will not alter cardiac involvement in the development of rheumatic fever. Some suggest the use of ...
*  MYL4
Auckland LM, Lambert SJ, Cummins P (November 1986). "Cardiac myosin light and heavy chain isotypes in tetralogy of Fallot". ... Schaub MC, Hefti MA, Zuellig RA, Morano I (February 1998). "Modulation of contractility in human cardiac hypertrophy by myosin ... Morano I, Haase H (May 1997). "Different actin affinities of human cardiac essential myosin light chain isoforms". FEBS Letters ... Shift in atrial myosin heavy chains and in ventricular myosin light chains". European Heart Journal. 5 Suppl F: 85-93. doi: ...
*  MYBPC1
"Localization of the binding site of the C-terminal domain of cardiac myosin-binding protein-C on the myosin rod". Biochem J. ... 2006). "Four and a half LIM protein 1 binds myosin-binding protein C and regulates myosin filament formation and sarcomere ... with skeletal and cardiac myosin is a property of the C-terminal immunoglobulin domain". J. Biol. Chem. 272 (33): 20866-72. doi ... Myosin-binding protein C, slow-type is a protein that in humans is encoded by the MYBPC1 gene. GRCh38: Ensembl release 89: ...
*  MYL2
"Cardiac myosin light chain kinase is necessary for myosin regulatory light chain phosphorylation and cardiac performance in ... Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) also known as the regulatory light chain of myosin ... Loss of cardiac MLCK in mice results in loss of cardiac MLC-2v phosphorylation and cardiac abnormalities. Mutations in MYL2 ... Ventricular myosin light chain-2 (MLC-2v) refers to the ventricular cardiac muscle form of myosin light chain 2 (Myl2). MLC-2v ...
*  MYBPC2
This gene encodes a member of the myosin-binding protein C family. This family includes the fast-, slow- and cardiac-type ... with skeletal and cardiac myosin is a property of the C-terminal immunoglobulin domain". The Journal of Biological Chemistry. ... "Support for a trimeric collar of myosin binding protein C in cardiac and fast skeletal muscle, but not in slow skeletal muscle ... "A frameshift deletion mutation in the cardiac myosin-binding protein C gene associated with dilated phase of hypertrophic ...
*  Omecamtiv mecarbil
Thus due to the unique cardiac myosin activation mechanism, omecamtiv mecarbil could safely improve cardiac function within ... Teerlink, JR (2009). "A novel approach to improve cardiac performance: cardiac myosin activators". Heart Fail Rev. 14 (4): 289- ... "Improvement of cardiac function by a cardiac myosin activator in conscious dogs with systolic heart failure". Circ Heart Fail. ... "The effects of the cardiac myosin activator, omecamtiv mecarbil, on cardiac function in systolic heart failure: a double-blind ...
*  John M Squire
Atomic model of the human cardiac muscle myosin filament. Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):318-323. http://www. ... General model of myosin filament structure. III. Molecular packing arrangements in myosin filaments. J Mol Biol. 1973 Jun 25;77 ... polarity in the myosin filaments of vertebrate smooth muscle, and the proposal of a general packing scheme of myosin molecules ... Probing muscle myosin motor action: X-ray (m3 and m6) interference measurements report motor domain not lever arm movement. J ...
*  MYL7
"Cardiac myosin light chain kinase is necessary for myosin regulatory light chain phosphorylation and cardiac performance in ... "Entrez Gene: MYL7 myosin, light chain 7, regulatory". "Protein sequence of human MYL7 (Uniprot ID: Q01449)". Cardiac Organellar ... Rottbauer W, Wessels G, Dahme T, Just S, Trano N, Hassel D, Burns CG, Katus HA, Fishman MC (August 2006). "Cardiac myosin light ... Expression of ALC-2 has been shown to correlate with expression of alpha-myosin heavy chain in cardiac atria of non-human ...
*  Samuel Victor Perry
... his team were unable to establish the precise function of regulatory light chains in vertebrate skeletal and cardiac myosins, ... Perry furthered his research by isolating the 'head' fragment of myosin by fractionating the myosin and its proteolytic ... Further observation of the myofibrils, and the crude preparations of the extracted contractile protein actins and myosins taken ... Perry continued his research at Birmingham, and spent considerable research on myosin light chain phosphorylation. Although he ...
*  List of MeSH codes (D12.776)
... myosin type i MeSH D12.776.210.500.600.470 - myosin type ii MeSH D12.776.210.500.600.470.249 - cardiac myosins MeSH D12.776. ... myosin type i MeSH D12.776.220.525.475.475 - myosin type ii MeSH D12.776.220.525.475.475.124 - cardiac myosins MeSH D12.776. ... myosin type iii MeSH D12.776.220.525.475.681 - myosin type iv MeSH D12.776.220.525.475.750 - myosin type v MeSH D12.776.220.525 ... myosin heavy chains MeSH D12.776.210.500.600.200 - myosin light chains MeSH D12.776.210.500.600.300 - myosin subfragments MeSH ...
*  Equine anatomy
Muscle fibers have myofibrils, which are able to contract due to actin and myosin. A muscle together with its tendon and bony ... A muscular ring, called the cardiac sphincter, connects the stomach to the esophagus. This sphincter is very well developed in ...
*  List of MeSH codes (D08)
... myosin type i MeSH D08.811.277.040.025.525.750 --- myosin type ii MeSH D08.811.277.040.025.525.750.124 --- cardiac myosins MeSH ... myosin type iii MeSH D08.811.277.040.025.525.843 --- myosin type iv MeSH D08.811.277.040.025.525.875 --- myosin type v MeSH ... nonmuscle myosin type iia MeSH D08.811.277.040.025.525.750.500 --- nonmuscle myosin type iib MeSH D08.811.277.040.025.525. ... 750.750 --- skeletal muscle myosins MeSH D08.811.277.040.025.525.750.875 --- smooth muscle myosins MeSH D08.811.277.040.025.525 ...