Goldberg SJ, Comerci GD, Feldman L (January 1988). "Cardiac output and regional myocardial contraction in anorexia nervosa". ... Some individuals may also have a decrease in cardiac contractility. Cardiac complications can be life-threatening, but the ... Anorexia nervosa increases the risk of sudden cardiac death, though the precise cause is unknown. Cardiac complications include ... Cardiac complications can include arrhythmias, abnormally slow heart beat, low blood pressure, decreased size of the heart ...
Ouabain Digoxin Myocardial infarction Toxicity Detoxification Muscle contraction Cardiac glycosides Sigma-Aldrich. " ... He also found out that the use of cardiac stimulant might alleviate myocardial depression in the presence of shock (first ... Cymarin (or k-strophanthidin) is a cardiac glycoside which works as an inhibitor of Na+ /K+-ATPase . This inhibition has an ... That influx drives the sarcoplasmatic reticulum of the cardiac muscles to take up and release Ca2+. This leads to the mentioned ...
There is a slight decrease in heart rate while myocardial oxygen consumption is unaffected. The increased cardiac output is ... Current inotropic therapies work by increasing the force of cardiac contraction, such as through calcium conduction or ... The combination of increased and prolonged cross-bridge formation prolongs myocardial contraction. Thus, the overall clinical ... Bers, DM (Jan 2002). "Cardiac excitation-contraction coupling". Nature. 415 (6868): 198-205. Bibcode:2002Natur.415..198B. doi: ...
... is a determinant of stroke volume (in addition to preload, and strength of myocardial contraction). Following ... As afterload increases, cardiac output decreases. Cardiac imaging is a somewhat limited modality in defining afterload because ... Afterload is a determinant of cardiac output. Cardiac output is the product of stroke volume and heart rate. ... This may start a vicious circle, in which cardiac output is reduced as oxygen requirements are increased. Afterload can also be ...
... myocardial infarction and cardiac death. In men with coronary heart disease and in women with or without coronary heart disease ... The myocardial scarring that occurs in myocardial infarction and also in the surgical repair of congenital heart disease can ... ed.). "Premature Ventricular Contractions (PVCs, PVC): What happens during a premature ventricular contraction?". MedicineNet. ... ed.). "Premature Ventricular Contractions (PVCs, PVC): What causes premature ventricular contractions?". MedicineNet. Retrieved ...
Cardiac traumas such as myocardial infarction (commonly called a heart attack), myocarditis, peripartum cardiomyopathy, ... This decreases the preload and results in a left-shift and loss of the normal isovolumic contraction line. Under conditions of ... Acute cardiac unloading is able to functionally uncouple the heart from cardiac output, allowing the heart to rest and recover ... Acute cardiac unloading decreases cardiac MVO2 and has been demonstrated to limit the amount of scar tissue that forms, thus ...
... as well as myocardial mass. Tagging sequences excite a grid pattern that deforms with cardiac contraction allowing strain to be ... Captur, Gabriella; Manisty, Charlotte; Moon, James C (15 September 2016). "Cardiac MRI evaluation of myocardial disease". Heart ... Cardiac magnetic resonance imaging (cardiac MRI, CMR), also known as cardiovascular MRI, is a magnetic resonance imaging (MRI) ... Initial attempts to image the heart were confounded by respiratory and cardiac motion, solved by using cardiac ECG gating, ...
Cardiac fibroblasts are vital supporting cells within cardiac muscle. They are unable to provide forceful contractions like ... "2014 ESC/EACTS Guidelines on myocardial revascularization: the Task Force on Myocardial Revascularization of the European ... During contraction of a cardiac muscle cell, the long protein myofilaments oriented along the length of the cell slide over ... The cardiac action potential subsequently triggers muscle contraction by increasing the concentration of calcium within the ...
While it does increase the magnitude of myocardial contractility, the duration of the contraction is only slightly increased. ... Cardiac glycosides, particularly digoxin, have been conventionally used for treatment of common cardiac problems, mainly heart ... Digoxin, as a cardiac glycoside, has a chemical structure basically similar to that of estradiol. Digoxin has the ability to ... Cardiac arrhythmias may also occur when patients are prescribed digoxin alongside thiazides and loop diuretics. Digitalis (i.e ...
Micrograph showing karyolysis and contraction band necrosis in an individual that had a myocardial infarction (heart attack). ... cardiac myocytes (right of image) in an individual that had a myocardial infarction. Apoptosis Necrosis Pyknosis Karyorrhexis ... Micrograph showing karyolysis and contraction band necrosis (left of image) and ischemic (nucleated) ...
After a myocardial infarction (MI), cardiac myocyte death can be triggered by necrosis, apoptosis, or autophagy, leading to ... Eventually, diastolic function, or the heart's ability to relax between contractions may become impaired, further causing ... Besides, the cardiac interstitium which consisted of largely Type I and Type III collagen fibres are also involved in cardiac ... Besides, reduced expression of V1 myosin and L-type calcium channels on cardiac myocytes are also thought to cause cardiac ...
... H&E stain. Contraction band necrosis. PTAH. Myocardial infarction Timeline of myocardial infarction ... Contraction band necrosis is a type of uncontrolled cell death (necrosis) unique to cardiac myocytes and thought to arise in ... They can be thought of extra thick striae, typical of cardiac muscle and striated muscle. Contraction band necrosis is thought ... It is a characteristic histologic finding of a recent myocardial infarction (heart attack) that was partially reperfused. The ...
In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of ... May 2008). "Cardiac Contractility Modulation Electrical Signals Improve Myocardial Gene Expression in Patients With Heart ... Rather, the aim is to enhance the heart's natural contraction (the native cardiac contractility) sustainably over long periods ... Mar 2012). "The effect of device-based cardiac contractility modulation therapy on myocardial efficiency and oxidative ...
... and reduced cardiac hypertrophy 1 week post-myocardial infarction. In support of the adenoviral experiments, S100A1 transgenic ... Kettlewell S, Most P, Currie S, Koch WJ, Smith GL (December 2005). "S100A1 increases the gain of excitation-contraction ... "Cardiac S100A1 protein levels determine contractile performance and propensity toward heart failure after myocardial infarction ... "S100A1 gene therapy preserves in vivo cardiac function after myocardial infarction". Molecular Therapy. 12 (6): 1120-9. doi: ...
... the former is produced by the active contraction of the cardiac musculature contraction while the second by its relaxation. The ... Thus, it is the contraction of the ascending segment of the myocardial band that paradoxically increases the ventricular volume ... The insights provided by the ventricular myocardial band model allows glimpses of possible advances in cardiac surgical ... His work can be found in reference books on anatomy and cardiac surgery. Torrent-Guasp started his cardiac research during ...
Overall, adenosine decreases the heart's rate and force of contraction, which increases blood supply to the cardiac muscle. ... It is also used in the treatment of heart block due to acute inferior myocardial infarction. It can also cause cardiac arrest. ... While it has been suggested for use in cardiac arrest evidence does not support a benefit. Aminophylline can lead to ... pp169 Hayward E; Showler L; Soar J (2007), "Aminophylline in bradyasystolic cardiac arrest", Emerg. Med. J., 24 (8): 582-3, doi ...
... ventricular mass observed after short-duration exposure to microgravity may be the result of a contraction of the myocardial ... The investigators observed no change in the number of premature ventricular contractions of premature atrial contractions per ... cardiac remodeling, and dehydration medications that interfere with the cardiac potassium ion channels. Which of these factors ... Cardiac rhythm disturbances could jeopardize mission objectives and, at the most extreme, the life of crewmembers. The worst- ...
... which increases the force of contraction needed to pump blood) and cardiac amyloidosis (in which misfolded proteins are ... As such, it can be caused by a wide number of conditions, including myocardial infarction (in which the heart muscle is starved ... The general effect is one of reduced cardiac output and increased strain on the heart. This increases the risk of cardiac ... resulting in inadequate cardiac output. In general, this is caused by dysfunction or destruction of cardiac myocytes or their ...
... the myocardial muscle will be stretched more than usual and as a result there will be an increase in myocardial contraction, ... There may initially be a tachycardia as a compensatory mechanism to try to maintain cardiac output. Other explanation is due to ... That was supposed to betoken the end.... Euler, DE (June 1999). "Cardiac alternans: mechanisms and pathophysiological ... or other cardiac risk factors. One explanation is that in left ventricular dysfunction, the ejection fraction will decrease ...
This period of the cardiac cycle is called isovolumic contraction. Because the contraction starts near the base of the left ... such as an aneurysm following myocardial infarction A pulse deficit between the PMI and periphery may occur in some arrhythmias ... such as premature ventricular contraction or atrial fibrillation. Sustained apex beat, namely prolonged upward cardiac force ... from the sternum at which the cardiac impulse can be felt. The cardiac impulse is the vibration resulting from the heart ...
... that are integral to muscle contraction in skeletal muscle and cardiac muscle, but not smooth muscle. Measurements of cardiac- ... a type of myocardial infarction involving severe constriction of the cardiac blood vessels. After a myocardial infarction ... Cardiac troponins are a marker of all heart muscle damage, not just myocardial infarction, which is the most severe form of ... A person who recently had a myocardial infarction would have an area of damaged heart muscle and elevated cardiac troponin ...
November 1996). "Osteopontin is produced by rat cardiac fibroblasts and mediates A(II)-induced DNA synthesis and collagen gel ... OPN-deficient NK cells fail to successfully navigate the contraction phase of the immune response, resulting in impaired ... Specifically, it plays a central role in the remodeling response to myocardial infarction, and is dramatically upregulated in ... November 1997). "Myocardial osteopontin expression is associated with left ventricular hypertrophy". Circulation. 96 (9): 3063- ...
... with each contraction (or heartbeat). It can refer to the cardiac atrium, ventricle, gall bladder, or leg veins, although if ... doi:10.1016/0002-9149(64)90274-7. Bartle SH, Sanmarco ME, Dammann J (1965). "5. Ejected fraction: An index of myocardial ... Nylin G (1933). "The relation between heart volume and cardiac output per beat as a measure of cardiac activity". Svenska ... The first common measurement method is echocardiography, although cardiac magnetic resonance imaging (MRI), cardiac computed ...
... s support synchronized contraction of cardiac tissue in a wave-like pattern so that the heart can work like a ... Forceful myocardial contraction, in turn mainly caused by ventricular fibrillation or electrical injury. Additional signs ... Square-shaped nuclei, indicating forceful myocardial contraction. This article incorporates text available under the CC BY 4.0 ... Intercalated discs or lines of Eberth are microscopic identifying features of cardiac muscle. Cardiac muscle consists of ...
... which in turn results in increased force of myocardial muscle contractions.[citation needed] In other words, at precisely the ... are the two chemically similar cardiac glycosides: digitoxin and digoxin. Like other cardiac glycosides, these toxins exert ... leading to cardiac arrest and finally death. Extracted from the leaves, this same cardiac glycoside digitoxin is used as a ... However, digitoxin, digoxin and several other cardiac glycosides, such as ouabain, are known to have steep dose-response curves ...
Absolute contraindications to cardiac stress test include: Acute myocardial infarction within 48 hours Unstable angina not yet ... Premature ventricular contractions, both multifocal or triplet; heart block; supraventricular tachycardia or bradyarrhythmias ... A cardiac stress test (also referred to as a cardiac diagnostic test, cardiopulmonary exercise test, or abbreviated CPX test) ... Side effects from cardiac stress testing may include[citation needed] Palpitations, chest pain, myocardial infarction, ...
In cardiomyocytes, or cardiac muscle cells, muscular contraction takes place due to movement at a structure referred to as the ... L-type calcium channels are more commonly found in myocardial tissue throughout the heart whereas T-type calcium channels are ... This process is known as excitation-contraction coupling. This contraction pushes blood inside the heart and from the heart to ... rhythmic contraction of the heart muscle. One of the most incredible attributes of cardiac muscle is the ability to ...
The cardiac centers monitor baroreceptor firing to maintain cardiac homeostasis, a mechanism called the baroreceptor reflex. ... Severe myocardial infarction (commonly called a heart attack) can lead to a decreasing heart rate, since metabolic reactions ... Heart rate (or pulse rate) is the frequency of the heartbeat measured by the number of contractions of the heart per minute ( ... Since HRmax varies by individual, the most accurate way of measuring any single person's HRmax is via a cardiac stress test. In ...
In order to maximize efficiency of contractions and cardiac output, the conduction system of the heart has: Substantial atrial ... Like a neuron, a given myocardial cell has a negative membrane potential when at rest. Stimulation above a threshold value ... Contraction that squeezes blood towards the exit is more efficient than a simple squeeze from all directions. Although the ... Sustained contraction of the heart without relaxation would be fatal, and this is prevented by a temporary inactivation of ...
... vasoconstriction can cause cardiac output reduction or even fatal heart complication particularly in those with weak myocardial ... are viable since there were many successful cases reported while given the physiological role of calcium on muscle contraction ... If vasodilatory shock being left untreated, even brief hypotensive periods can result in myocardial and renal injury. It can ... Reversing the underlying causes of vasodilatory shock, stabilizing hemodynamic, preventing renal, myocardial, and other organs ...