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*  Adenocarcinoma
This cancer usually is seen peripherally in the lungs, as opposed to small cell lung cancer and squamous cell lung cancer, ... and carcinoma, which describes a cancer that has developed in the epithelial cells. Clear-cell adenocarcinoma From adeno-, " ... Invasive ductal carcinoma: 55% of breast cancers Ductal carcinoma in situ: 13% Invasive lobular carcinoma: 5% The vast majority ... There will also be a noticeable increase in the incidence of mitosis, or cell divisions. Nearly 40% of lung cancers are ...
*  Squamous cell carcinoma
When associated with the lung, it is typically a centrally located large cell cancer (non-small cell lung cancer or NSCLC). It ... Adenoid squamous cell carcinoma Basaloid squamous cell carcinoma Clear-cell squamous cell carcinoma Spindle-cell squamous cell ... Large cell nonkeratinizing squamous cell carcinoma (Code 8072/3) Small cell keratinizing squamous cell carcinoma (Code 8073/3) ... Signet-ring-cell squamous cell carcinoma (occasionally rendered as "signet-ring-cell squamous cell carcinoma") is a ...
*  Timeline of liver cancer
"Liver Transplantation for the Treatment of Small Hepatocellular Carcinomas in Patients with Cirrhosis". New England Journal of ... Timeline of lung cancer Timeline of brain cancer Timeline of colorectal cancer Timeline of pancreatic cancer Timeline of ... "Hepatitis G infection: role in cryptogenic chronic liver disease and primary liver cell cancer in the UK. Trent Hepatitis C ... "Hepatocellular Carcinoma (Liver Cancer)". Retrieved 30 September 2016. "Risk Factors for the Rising Rates of Primary Liver ...
*  Non-small-cell lung carcinoma
... (NSCLC) is any type of epithelial lung cancer other than small cell lung carcinoma (SCLC). NSCLC ... using a uniform scheme for non-small cell lung carcinoma, small-cell lung carcinoma and broncho-pulmonary carcinoid tumors. ... Historically, adenocarcinoma was more often seen peripherally in the lungs than small cell lung cancer and squamous cell lung ... "National Cancer Institute Non-Small Cell Lung Cancer Treatment (PDQ®)". Retrieved 12 May 2015. "Non-Small Cell Lung Cancer ...
*  Combined small-cell lung carcinoma
... lung carcinomas are divided into 8 major taxa: Squamous cell carcinoma Small cell carcinoma Adenocarcinoma Large cell carcinoma ... Combined small cell lung carcinoma (or c-SCLC, and rarely rendered as "small-cell lung carcinoma") is a form of multiphasic ... December 2007). "Sequential occurrence of non-small cell and small cell lung cancer with the same EGFR mutation". Lung Cancer. ... December 1982). "The clinical behavior of "mixed" small cell/large cell bronchogenic carcinoma compared to "pure" small cell ...
*  Topotecan
Ovarian cancer (FDA May 1996). Cervical cancer (FDA June 2006). Small cell lung carcinoma (SCLC) (FDA Oct 2007). As of 2016 ... Topotecan is often given in combination with Paclitaxel as first line treatment for extensive-stage small-cell lung cancer. ... "FDA Rubber-Stamps APP Pharma's Generic Topotecan for Small Cell Lung and Cervical Cancers". 30 Nov 2010. DNA Topoisomerases and ... In addition, topotecan is experimentally treating Non-small cell lung cancer, Colorectal Cancer, Breast cancer, Non-Hodgkin ...
*  Laboratory Syrian hamster
Syrian hamsters are a model for researching Non-small-cell lung carcinoma, which is one of the types of human lung cancer. In ... "Current role of surgery in small cell lung carcinoma". Journal of Cardiothoracic Surgery. 4 (1): 30. doi:10.1186/1749-8090-4-30 ... Oral squamous-cell carcinoma is a common cancer in humans and difficult to treat. Scientists studying this disease broadly ... The scientist can take cell samples from the mouth of the hamster to measure the development of the cancer. This process has ...
*  Hypertrophic osteoarthropathy
It is especially associated with non-small cell lung carcinoma. These patients often get clubbing and increased bone deposition ... Treatment of lung cancer or other causes of hypertrophic osteoarthropathy results in regression of symptoms for some patients. ... Hypertrophic osteoarthropathy is one of many distant effect disorders due to cancer, with lung cancer being the most common ... The condition may occur alone (primary), or it may be secondary to diseases like lung cancer. ...
*  Necitumumab
It was counterproductive in non-squamous non-small-cell lung carcinoma. International Nonproprietary Names for Pharmaceutical ... name Portrazza for use with gemcitabine and cisplatin in previously untreated metastatic squamous non-small-cell lung carcinoma ...
*  Large cell neuroendocrine carcinoma of the lung
It is currently considered to be a subtype of large cell lung carcinoma. LCNEC is often generically grouped among the non-small ... Large cell neuroendocrine carcinoma of the lung (LCNEC) is a highly malignant neoplasm arising from transformed epithelial ... cell lung carcinomas. The World Health Organization classification of lung tumors recognizes a variant of LCNEC, namely " ... Lung Cancer Home Page. The National Cancer Institute site containing further reading and resources about lung cancer. [1]. ...
*  Quinazoline
... -containing drugs Gefitinib for treatment of non-small-cell lung carcinoma. Lapatinib for treatment of advanced- ... "Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non-Small-Cell Lung Cancer to ... Lapatinib eliminates the growth of breast cancer stem cells that cause tumor growth. The binding of lapatinib to the ATP- ... the cancer stem cell. Nelson MH, Dolder CR (February 2006). "Lapatinib: a novel dual tyrosine kinase inhibitor with activity in ...
*  Tivantinib
Possible applications include non-small-cell lung carcinoma, hepatocellular carcinoma, and oesophageal cancer. In 2017, it was ... Tivantinib (ARQ197; by Arqule, Inc.) is an experimental small molecule anti-cancer drug. It is a bisindolylmaleimide that binds ... "ArQule Announces Commencement of Phase 3 Clinical Trial with Tivantinib in Hepatocellular Carcinoma by Partner Kyowa Hakko ... announced that a phase III clinical trial for advanced hepatocellular carcinoma had failed to meet the primary endpoint. " ...
*  IsoRay
Intraoperative 125I brachytherapy for high-risk stage I non-small cell lung carcinoma. Int J Radiat Oncol Biol Phys 1999;44: ... Lung Because of the essential function of the lungs themselves, and the proximity of other crucial organs, it is necessary to ... high doses of radiation can be applied to a very small target region while sparing surrounding tissues from damage. The unique ... Brachytherapy seeds can be implanted directly within a tumor site delivering intense radiation to a small target area as a ' ...
*  Opsoclonus myoclonus syndrome
In adults, most cases are associated with breast carcinoma or small-cell lung carcinoma. It is one of the few paraneoplastic ( ... and T-cell markers in opsoclonus-myoclonus syndrome: immunophenotyping of CSF lymphocytes". Neurology. 62 (9): 1526-32. doi: ... possibly by expanding the memory B cell population. Studies have generally asserted that 70-80% of children with OMS will have ...
*  HTATIP2
Shtivelman E (Jun 1997). "A link between metastasis and resistance to apoptosis of variant small cell lung carcinoma". Oncogene ... Cell. Biol. 20 (2): 583-93. doi:10.1128/MCB.20.2.583-593.2000. PMC 85138 . PMID 10611237. Xiao H, Palhan V, Yang Y, Roeder RG ( ... Cell. Biol. 24 (16): 7091-101. doi:10.1128/MCB.24.16.7091-7101.2004. PMC 479715 . PMID 15282309. Suzuki Y, Yamashita R, Shirota ... NicAmhlaoibh R, Shtivelman E (2001). "Metastasis suppressor CC3 inhibits angiogenic properties of tumor cells in vitro". ...
*  Targeted therapy of lung cancer
In contrast, non-small cell lung carcinomas (NSCLC's) are more likely to remain localized to the thorax during development, and ... Most small cell lung carcinomas (SCLC's) metastasize to distant organs early on in their course, rendering surgery ineffective ... While there have been no randomized clinical trials of targeted agents in combined small-cell lung carcinoma (c-SCLC),[citation ... Dempke WC, Suto T, Reck M (March 2010). "Targeted therapies for non-small cell lung cancer". Lung Cancer (Amsterdam, ...
*  ALK inhibitor
About 4-7% of non-small cell lung carcinomas (NSCLC) have EML4-ALK translocations. crizotinib (Xalkori) (also a ROS1 inhibitor ... Nelsen (2010). "ALK Inhibitors: Possible New Treatment for Lung Cancer". Farmer (2010). "Non-Small-Cell Lung Cancer Standards ... Discontinued ASP-3026 (Astellas) NPM-ALK is a different variation/fusion of ALK that drives anaplastic large-cell lymphomas ( ... "". "FDA Approves Ceritinib for ALK-Positive Lung Cancer". Medscape. April 29, 2014. "Dalantercept". AdisInsight. Retrieved 15 ...
*  Dichloroacetic acid
Lemmo, W; Tan, G (2016). "Prolonged Survival After Dichloroacetate Treatment of Non-Small-Cell Lung Carcinoma-Related ... cell death) of the malignant cells. However, in vitro work with DCA on neuroblastomas (which have fewer recognised ... It can kill normal cells as well. A randomized controlled trial in children with congenital lactic acidosis found that while ... Observations in vitro and of tumours extracted from those five patients suggest that DCA might act against cancer cells by ...
*  PARAMOUNT trial
... not have non-superficial squamous-cell carcinoma or a mixture of both small-cell carcinoma and non-small-cell lung carcinoma or ... The PARAMOUNT trial is a clinical trial studying non-small-cell lung carcinoma (NSCLC). The trial was sponsored by Eli Lilly ... For patients with advanced non-small cell lung carcinoma (NSCLC), maintenance therapy is sometimes used when the initial ... participants must in the trial must have stage IIIB or IV nonsquamous non-small-cell lung carcinoma and have at least one ...
*  ELAV-like protein 3
1994). "A hippocampal protein associated with paraneoplastic neurologic syndrome and small cell lung carcinoma". Biochem. ... Cell. Biol. 20 (13): 4765-72. doi:10.1128/MCB.20.13.4765-4772.2000. PMC 85909 . PMID 10848602. Sakai K, Kitagawa Y, Hirose G ( ...
*  Hemoptysis
Lung cancer, including both non-small cell lung carcinoma and small cell lung carcinoma. Sarcoidosis Aspergilloma Tuberculosis ... removal of a lung lobe or removal of the entire lung. Non-small-cell lung cancer can also be treated with erlotinib or ... Hemoptysis is the coughing up of blood or blood-stained mucus from the bronchi, larynx, trachea, or lungs. This can occur with ... Selective bronchial intubation can be used to collapse the lung that is bleeding. Also, endobronchial tamponade can be used. ...
*  Fred Trueman
Trueman was diagnosed with small cell carcinoma of the lung in May 2006. He died of the disease on 1 July 2006 at Airedale ... This award was discontinued in 2004, two years before Trueman was diagnosed with lung cancer, because its organisers feared it ...
*  CHRNB4
1992). "Neuronal-type nicotinic receptors in human neuroblastoma and small-cell lung carcinoma cell lines". FEBS Lett. 312 (1 ... Cell. Mol. Biol. (Noisy-le-grand). 43 (3): 433-42. PMID 9193799. Gerzanich V, Kuryatov A, Anand R, Lindstrom J (1997). ""Orphan ... subunits beta3 and beta4 and expression of seven nAChR subunits in the human neuroblastoma cell line SH-SY5Y and/or IMR-32". ... Nicotine Activity on Chromaffin Cells edit]] The interactive pathway map can be edited at WikiPathways: " ...
*  Metastasis suppressor
... melanoma and non-small cell lung carcinoma. Clinically BRMS1 expression correlates with survival in breast cancer and non-small ... High expression of CTGF is correlated with improved survival in colorectal cancer, non-small cell lung carcinoma and ... hepatocellular and non-small cell carcinoma. It affects the MAPK and cytoskeleton-organizing cellular pathways, which ... cell lung carcinoma. KISS1 is found in melanoma and breast cancers. It acts by synthesizing a protein receptor. RHoGD12 is ...
*  Mucinous cystadenocarcinoma of the lung
For treatment purposes, MCACL has been traditionally considered a non-small cell lung carcinoma (NSCLC). Complete radical ... mucoepidermoid carcinoma, mucinous bronchioloalveolar carcinoma, signet ring cell adenocarcinoma, mucinous cystadenocarcinoma, ... Tsuta K; Ishii G; Nitadori J (May 2006). "Comparison of the immunophenotypes of signet-ring cell carcinoma, solid ... and mucinous bronchioloalveolar carcinoma of the lung characterized by the presence of cytoplasmic mucin". J. Pathol. 209 (1): ...
*  Prostaglandin-endoperoxide synthase 2
Cell Dev. Biol. 17 (5): 544-54. doi:10.1016/j.semcdb.2006.09.001. PMID 17071117. Minghetti L, Pocchiari M (2007). " ... Saba N, Jain S, Khuri F (2004). "Chemoprevention in lung cancer". Curr Probl Cancer. 28 (5): 287-306. doi:10.1016/j. ... small amounts of oxidation products are formed due to the oxygen trapping of an allylic radical intermediate at positions 13 ... "A new cyclo-oxygenase-2 gene variant in the Han Chinese population is associated with an increased risk of gastric carcinoma". ...
*  ALDH7A1
"ALDH7A1 expression is associated with recurrence in patients with surgically resected non-small-cell lung carcinoma". Future ... Cell. 122 (6): 957-68. doi:10.1016/j.cell.2005.08.029. PMID 16169070. Been JV, Bok LA, Andriessen P, Renier WO (Dec 2005). " ... "The ALDH7A1 genetic polymorphisms contribute to development of esophageal squamous cell carcinoma". Tumour Biology: the Journal ... Antiquitin may also play a protective role for DNA in cell growth, as the protein is found to be up-regulated during the G1-S ...