The rationale for the use of bland embolization for hepatocellular carcinoma(HCC) and/or other hyper-vascular tumors is based ... Chamberlain RS, Canes D, Brown KT, Saltz L, Jarnagin W, Fong Y, Blumgart LH (April 2000). "Hepatic neuroendocrine metastases: ... The m o common indication of this therapy is for treatment of unresectable primary hepatocellular carcinoma, based on anatomic ... Llovet JM, Brú C, Bruix J (1999). "Prognosis of hepatocellular carcinoma: the BCLC staging classification". Seminars in Liver ...
It is a rare form of a neuroendocrine tumour. Most insulinomas are benign in that they grow exclusively at their origin within ... Streptozotocin is used in islet cell carcinomas which produce excessive insulin. Combination chemotherapy is used, either ... About 2% of patients develop diabetes mellitus after their surgery.[citation needed] Insulinomas are rare neuroendocrine ... Insulinomas are one of the functional pancreatic neuroendocrine tumour (PNET) group ("functional" because it increases ...
... prepubertal type Testicular neuroendocrine tumor, prepubertal type Mixed teratoma and yolk sac tumor, prepubertal type Sex cord ... germ cell neoplasia Gonadoblastoma The germinoma family of tumors Seminoma Nonseminomatous germ cell tumors Embryonal carcinoma ...
In immunohistochemistry it can be used to identify a range of neuroendocrine tumours and is highly specific for both benign and ... "Elevated serum chromogranin A is detectable in patients with carcinomas at advanced disease stages". Annals of Clinical and ... Chromogranin A or parathyroid secretory protein 1 (gene name CHGA) is a member of the granin family of neuroendocrine secretory ... chromogranin-A (CgA)+ Pulmonary neuroendocrine cells account for 0.41% of all epithelial cells in the conducting airway, but ...
In 1977, MIA PaCa-2 cells were derived from the carcinoma of a 65-year-old male.[citation needed] The cells exhibit CK5.6, AE1/ ... 17 February 2016). "MIA PaCa-2 and PANC-1 - pancreas ductal adenocarcinoma cell lines with neuroendocrine differentiation and ... 3 May 1977). "Purification and characterization of a plasminogen activator secreted by cultured human pancreatic carcinoma ...
... renal cell carcinoma), liver cancer (hepatocellular carcinoma) in adults previously treated with the medicine sorafenib, as ... In 1995, the group launched Somatuline, used to treat hypersecretion of growth hormones (acromegaly) and in neuro-endocrine ... Used for the treatment of neuroendocrine tumors (NETs), carcinoid syndrome or acromegaly. Onivyde (irinotecan liposome ... which received marketing authorization the same year for the second-line treatment of advanced renal cell carcinoma. In January ...
In neuroendocrine tumor patients with advanced well-differentiated disease and progression on somatostatin analogs, 177Lu- ... neuroblastoma or medullary thyroid carcinoma. Various approaches to approve effectiveness and limit side effects are being ... A comparative cohort study of 1051 neuroendocrine tumor patients undergoing 90Y-DOTATOC (n=910) or 177Lu-DOTATOC (n=141) ... Kjaer, A; Knigge, U (June 2015). "Use of radioactive substances in diagnosis and treatment of neuroendocrine tumors". ...
Notably, the expression of mPRγ was significantly higher in endometrioid and clear cell carcinomas, which are closely related ... The mPRs mediate important physiological functions in male and female reproductive tracts, liver, neuroendocrine tissues, and ... and carcinomas: while mPRα is expressed at significantly higher levels than the others, an increased expression of mPRβ has ... neurosteroid signaling and neuroendocrine functions in neuronal cells". Neuroendocrinology. 96 (2): 162-71. doi:10.1159/ ...
Other exocrine cancers include adenosquamous carcinomas, signet ring cell carcinomas, hepatoid carcinomas, colloid carcinomas, ... Neuroendocrine tumors (NETs) are a diverse group of benign or malignant tumors that arise from the body's neuroendocrine cells ... undifferentiated carcinomas, and undifferentiated carcinomas with osteoclast-like giant cells. Solid pseudopapillary tumor is a ... As with other neuroendocrine tumors, the history of the terminology and classification of PanNETs is complex. PanNETs are ...
The second broad category of pancreatic tumor types are neuroendocrine tumors (also known as "endocrine" or "islet cell tumors ... acinar cell carcinomas account for 5% of exocrine pancreatic cancers and can be "functioning", and overproduce certain ... Perri, Giampaolo; Prakash, Laura R.; Katz, Matthew H. G. (September 2019). "Pancreatic neuroendocrine tumors". Current Opinion ... Burns, William R.; Edil, Barish H. (2012-03-01). "Neuroendocrine Pancreatic Tumors: Guidelines for Management and Update". ...
... basal cell carcinoma, and basal cell carcinoma with follicular differentiation". Int. J. Dermatol. 48 (7): 713-7. doi:10.1111/j ... immunohistochemical localization of neuroendocrine markers and CD10". Am. J. Surg. Pathol. 24 (10): 1361-71. doi:10.1097/ ... basal cell carcinoma with follicular differentiation (CD10 stromal and epithelial staining) and squamous cell carcinoma (strong ... Some benign T cells can be CD10+ Clear cell renal cell carcinoma (Clear cell RCC) CD10+ distinguishes renal cell carcinoma, ...
ATAs are also found in patients with Hashimoto's encephalopathy, a neuroendocrine disorder related to-but not caused by- ... and a greater percentage of patients with thyroid carcinoma. The presence of these antibodies can result in falsely low (or ... A subsequent elevation of the thyroglobulin level is an indication of recurrence of papillary or follicular thyroid carcinoma. ... Thyroglobulin is not produced by medullary or anaplastic thyroid carcinoma. Thyroglobulin levels are tested via a simple blood ...
Gires O, Eskofier S, Lang S, Zeidler R, Münz M (2003). "Cloning and characterisation of a 1.1 kb fragment of the carcinoma- ... and neuroendocrine prostate cancers. This antigen is the target of sacituzumab govitecan, an antibody-drug conjugate. GRCh38: ... This intronless gene encodes a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member ... March 1993). "Retroposition in a family of carcinoma-associated antigen genes". Molecular and Cellular Biology. 13 (3): 1507- ...
The absence of MYO5A in the brain can be associated with loco motor dysfunction and neuroendocrine abnormalities. As mention ... by miR-145 acts as a predictive marker of occult neck lymph node metastasis in human laryngeal squamous cell carcinoma". ... can be highly expressed on metastatic colorectal cancer tissues and neck lymph node metastasis of oral squamous cell carcinoma ...
Invasive ductal carcinoma: 55% of breast cancers Ductal carcinoma in situ: 13% Invasive lobular carcinoma: 5% The vast majority ... are typically not referred to as adenocarcinomas but rather are often called neuroendocrine tumors. Epithelial tissue sometimes ... Thus invasive ductal carcinoma, the most common form of breast cancer, is adenocarcinoma but does not use the term in its name- ... The adenoma, lacking the "carcinoma" attached to the end of it, suggests that it is a benign version of the malignant ...
188Re (Rhenium) as Rhenium-SCT for treatment of Non-Melanoma Skin Cancer (basal cell carcinoma or squamous cell carcinoma) ... imaging for neuroendocrine tumors, heat-damaged red blood cell imaging for identifying ectopic splenic tissue, and gastric ...
This protein shows potential use as a prognostic biomarker in various tumors, like gastric carcinoma. or melanoma has been ... "The transforming growth factor alpha gene family is involved in the neuroendocrine control of mammalian puberty". Molecular ... dysplasia and gastric carcinoma--an immunohistochemical study". Histopathology. 20 (4): 339-43. doi:10.1111/j.1365-2559.1992. ...
Recurrent or Metastatic PNET or GI-NET Neuroendocrine Tumors/Carcinoid With Elevated Biomarkers" at ClinicalTrials.gov " ... Combination With Paclitaxel and Carboplatin in Comparison With Paclitaxel and Carboplatin Against Anaplastic Thyroid Carcinoma ...
Due to their location deep in the retroperitoneum, most adrenocortical carcinomas are not diagnosed until they have grown quite ... and is composed of neuroendocrine (chromaffin) cells which produce and release epinephrine (adrenaline) into the bloodstream in ... Necrosis and hemorrhage are rare findings.[citation needed] Adrenocortical carcinoma (ACC) is a rare, highly aggressive cancer ... Adrenal cancer is the presence of malignant adrenal tumors, and includes neuroblastoma, adrenocortical carcinoma and some ...
Carcinoma cells in a primary tumor lose cell-cell adhesion mediated by E-cadherin repression and break through the basement ... "Androgen-targeted therapy-induced epithelial mesenchymal plasticity and neuroendocrine transdifferentiation in prostate cancer ... In urothelial carcinoma cell lines overexpression of HDAC5 inhibits long-term proliferation but can promote epithelial-to- ... Thus, EMT may present increased danger to cancer patients, as EMT not only enables the carcinoma cells to enter the bloodstream ...
Neoplastic CD57 positive cells are seen in conditions as varied as large granular lymphocytic leukaemia, small-cell carcinoma, ... In anatomical pathology, CD57 (immunostaining) is similar to CD56 for use in differentiating neuroendocrine tumors from others ... thyroid carcinoma, and neural and carcinoid tumours. Although the antigen is particularly common in carcinoid tumours, it is ... "CD8+ Immunosenescence Predicts Post-Transplant Cutaneous Squamous Cell Carcinoma in High-Risk Patients". Journal of the ...
2000). "Superficial undifferentiated small cell carcinoma of the esophagus showing an interesting growing pattern in histology ... see neuroendocrine tumor).The term dates back to at least 1975. Because the label "apudoma" is very general, it is preferred to ...
The WHO now divides these growths into neuroendocrine tumors and neuroendocrine cancers. Neuroendocrine tumors are growths that ... The term 'crypt cell carcinoma' has been used for them, and though perhaps more accurate than considering them carcinoids, has ... Neuroendocrine cancers are abnormal growths of neuroendocrine cells which can spread to other parts of the body. Specific to ... is a slow-growing type of neuroendocrine tumor originating in the cells of the neuroendocrine system. In some cases, metastasis ...
Eil C, Douglass EC, Rosenburg SM, Kano-Sueoka T (January 1981). "Receptor characteristics of the rat mammary carcinoma cell ... Kohtz AS, Frye CA (2012). "Dissociating behavioral, autonomic, and neuroendocrine effects of androgen steroids in animal models ...
... ductal carcinoma - ductal carcinoma in situ - ductal lavage - Dukes' classification - dumping syndrome - duodenitis - DX-52-1 ... neuroendocrine - neuroendocrine tumor - neuroepithelial - neurofibroma - neurofibromatosis type I - neurofibromatosis type 2 - ... carcinoma - carcinoma in situ - carcinomatosis - carcinosarcoma - carcinosis - carcinostatic - cardin (oncology) - carmustine ... basal cell carcinoma - basal cell nevus syndrome - basophil - batimastat - BAY 12-9566 - BAY 43-9006 - BAY 56-3722 - BAY 59- ...
Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is ... "The immunolocalization of PGP 9.5 in normal human kidney and renal cell carcinoma". Il Giornale di Chirurgia. 18 (10): 521-4. ... A novel cytoplasmic marker for neurones and neuroendocrine cells". FEBS Letters. 210 (2): 157-60. doi:10.1016/0014-5793(87) ... indicating that this protein plays a protective role in neuroendocrine cells and illustrating a link between diabetes and ...
Shah SA, Smith JK, Li Y, Ng SC, Carroll JE, Tseng JF (Mar 2011). "Underutilization of therapy for hepatocellular carcinoma in ... Hill JS, McPhee JT, McDade TP, Zhou Z, Sullivan ME, Whalen GF, Tseng JF (2009). "Pancreatic Neuroendocrine tumors: the impact ... Shah SA, Smith JK, Li Y, Ng SC, Carroll JE, Tseng JF (Oct 2010). "Underutilization of therapy for hepatocellular carcinoma in ... "Tumor registry versus physician medical record review: A head-tohead comparison of pancreatic neuroendocrine tumor cases. In ...
Neuroendocrine and Immune Responses in Humans During and After Long Term Stay at ISS (Immuno) Motion Perception: Vestibular ... Mechanisms of Colon Carcinoma Metastasis in Microgravity (CBOSS-01-Colon (ISS Experiment)) - NASA Archived 2010-03-24 at the ... Mechanisms of Colon Carcinoma Metastasis in Microgravity (CBOSS-01-Colon) Cellular Biotechnology Operations Support Systems: ... NASA Archived 2010-03-16 at the Wayback Machine Neuroendocrine and Immune Responses in Humans During and After Long Term Stay ...
Jeng L, Thorat A, Yang H, Yeh CC, Chen TH, Hsu SC (2015). "Impact of Everolimus On the Hepatocellular Carcinoma Recurrence ... neuroendocrine tumors (NET) of gastrointestinal (GI) or lung origin with unresectable, locally advanced or metastatic disease ( ... A group of patients with advanced metastasic bladder carcinoma treated with everolimus revealed a single patient who had a ... As of October 2010[update], Phase III trials are under way in gastric cancer, hepatocellular carcinoma, and lymphoma. The ...
Sipple JH (1961). "The association of pheochromocytoma with carcinoma of the thyroid gland". Am. J. Med. 31: 163-6. doi:10.1016 ... 1] Archived 2017-03-14 at the Wayback Machine 123I labeled metaiodobenzylguanidine for diagnosis of neuroendocrine tumors. ... described medullary (solid) thyroid carcinoma.[citation needed] In 1961 Sipple described a combination of a pheochromocytoma, ... described the combination of mucosal neuromas, pheochromocytoma and medullary thyroid carcinoma.[citation needed] In 1968 ...