It belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. ... Other names in common use include phosphoribulose isomerase, ribulose phosphate 4-epimerase, L-ribulose-phosphate 4-epimerase, ... In enzymology, a L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4) is an enzyme that catalyzes the interconversion of ribulose 5- ... Ribulose 5-phosphate 4-epimerase is found on the well studied L-arabinose operon. This operon consists of eight genes araA-araH ...
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and ... Other names in common use include UDP acetylglucosamine epimerase, uridine diphosphoacetylglucosamine epimerase, uridine ... In enzymology, an UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) is an enzyme that catalyzes the chemical reaction UDP-N- ... The systematic name of this enzyme class is UDP-N-acetyl-D-glucosamine 4-epimerase. ...
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and ... epimerase, uridine diphospho-N-acetylglucosamine 2'-epimerase, and uridine diphosphate-N-acetylglucosamine-2'-epimerase. This ... The UDP-N-acetylglucosamine 2-epimerase from rat liver displays both epimerase and kinase activity. As of late 2007, 4 ... UDP-N-acetylglucosamine 2-epimerase (hydrolysing) Not to be confused with N-acetylglucosamine 2-epimerase Swartley JS, Liu LJ, ...
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and ... Other names in common use include uridine diphosphoglucuronate 5'-epimerase, UDP-glucuronic acid 5'-epimerase, and C-5-uronosyl ... In enzymology, an UDP-glucuronate 5'-epimerase (EC 5.1.3.12) is an enzyme that catalyzes the chemical reaction UDP-glucuronate ... I. Uridine diphosphate-D-glucuronic acid-5-epimerase". The Journal of Biological Chemistry. 237 (3): 638-42. doi:10.1016/S0021- ...
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and ... In enzymology, an ADP-L-glycero-D-manno-heptose 6-epimerase (EC 5.1.3.20) is an enzyme that catalyzes the chemical reaction ADP ... The systematic name of this enzyme class is ADP-L-glycero-D-manno-heptose 6-epimerase. This enzyme participates in ... "The Mechanism of the Reaction Catalyzed by ADP-β-L-glycero-D-manno-heptose 6-Epimerase". J. Am. Chem. Soc. 126 (29): 8878-9. ...
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and ... The systematic name of this enzyme class is UDP-glucosamine 4-epimerase. MALEY F, MALEY GF (1959). "The enzymic conversion of ... In enzymology, an UDP-glucosamine 4-epimerase (EC 5.1.3.16) is an enzyme that catalyzes the chemical reaction UDP-glucosamine ...
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and ... UDP-galacturonate 4-epimerase, uridine diphosphoglucuronate epimerase, and UDP-D-galacturonic acid 4-epimerase. This enzyme ... The systematic name of this enzyme class is UDP-glucuronate 4-epimerase. Other names in common use include uridine diphospho-D- ... galacturonic acid, UDP glucuronic epimerase, uridine diphosphoglucuronic epimerase, ...
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and ... In enzymology, an aldose 1-epimerase (EC 5.1.3.3) is an enzyme that catalyzes the chemical reaction alpha-D-glucose ⇌ {\ ... The systematic name of this enzyme class is aldose 1-epimerase. Other names in common use include mutarotase, and aldose ...
This enzyme belongs to the isomerase family, specifically those racemases and epimerases which act on carbohydrates and their ... phosphoketopentose 3-epimerase, xylulose phosphate 3-epimerase, phosphoketopentose epimerase, ribulose 5-phosphate 3-epimerase ... Phosphopentose epimerase (also known as ribulose-phosphate 3-epimerase and ribulose 5-phosphate 3-epimerase, EC 5.1.3.1) ... D-ribulose 5-phosphate epimerase, D-ribulose-5-P 3-epimerase, D-xylulose-5-phosphate 3-epimerase, and pentose-5-phosphate 3- ...
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and ... The systematic name of this enzyme class is maltose 1-epimerase. Shirokane Y, Suzuki M (1995). "A novel enzyme, maltose 1- ... In enzymology, a maltose epimerase (EC 5.1.3.21) is an enzyme that catalyzes the chemical reaction alpha-maltose ⇌ {\ ... epimerase from Lactobacillus brevis IFO 3345". FEBS Lett. 367 (2): 177-9. doi:10.1016/0014-5793(95)00524-D. PMID 7796915. ...
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and ... In enzymology, a glucose-6-phosphate 1-epimerase (EC 5.1.3.15) is an enzyme that catalyzes the chemical reaction alpha-D- ... Wurster B, Hess B (1972). "Glucose-6-phosphate-1-epimerase from baker's yeast. A new enzyme". FEBS Lett. 23 (3): 341-344. doi: ... The systematic name of this enzyme class is D-glucose-6-phosphate 1-epimerase. This enzyme participates in glycolysis / ...
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and ... 5-epimerase, TDP-4-ketorhamnose 3,5-epimerase, dTDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase, and TDP-4-keto-L-rhamnose-3,5- ... The systematic name of this enzyme class is dTDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase. Other names in common use include ... In enzymology, a dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) is an enzyme that catalyzes the chemical reaction dTDP-4- ...
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and ... Other names in common use include polyglucuronate 5-epimerase, dermatan-sulfate 5-epimerase, urunosyl C-5 epimerase, and ... Assay and properties of the uronosyl C-5 epimerase". Biochem. J. 201 (3): 489-93. doi:10.1042/bj2010489. PMC 1163673. PMID ... In enzymology, a chondroitin-glucuronate 5-epimerase (EC 5.1.3.19) is an enzyme that catalyzes the chemical reaction ...
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and ... The systematic name of this enzyme class is L-ribulose-5-phosphate 3-epimerase. Other names in common use include L-xylulose 5- ... In enzymology, a L-ribulose-5-phosphate 3-epimerase (EC 5.1.3.22) is an enzyme that catalyzes the chemical reaction L-ribulose ... phosphate 3-epimerase, UlaE, and SgaU. This enzyme participates in ascorbate and aldarate metabolism. Yew WS, Gerlt JA (2002 ...
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and ... Other names in common use include acylglucosamine 2-epimerase, and N-acetylglucosamine 2-epimerase. This enzyme participates in ... They show that the N-acylglucosamine 2-epimerase monomer folds as a barrel composed of α-helices, in a manner known as (α/α)6- ... In enzymology, a N-acylglucosamine 2-epimerase (EC 5.1.3.8) is an enzyme that catalyzes the chemical reaction N-acyl-D- ...
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and ... Other names in common use include acylglucosamine-6-phosphate 2-epimerase, and acylglucosamine phosphate 2-epimerase. This ... In enzymology, a N-acylglucosamine-6-phosphate 2-epimerase (EC 5.1.3.9) is an enzyme that catalyzes the chemical reaction N- ... N-Acyl--D-Glucosamine 6-Phosphate 2-Epimerase". The Journal of Biological Chemistry. 240: 1525-30. doi:10.1016/S0021-9258(18) ...
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and ... cytidine diphosphodideoxyglucose epimerase, cytidine diphosphoparatose epimerase, and cytidine diphosphate paratose-2-epimerase ... It is also incorrectly known as CDP-abequose epimerase, and CDP-D-abequose 2-epimerase. This enzyme participates in starch and ... Other names in common use include CDP-paratose epimerase, cytidine diphosphoabequose epimerase, ...
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and ... UDP arabinose epimerase, uridine 5'-diphosphate-D-xylose 4-epimerase, and UDP-D-xylose 4-epimerase. This enzyme participates in ... In enzymology, an UDP-arabinose 4-epimerase (EC 5.1.3.5) is an enzyme that catalyzes the chemical reaction UDP-L-arabinose ⇌ {\ ... The systematic name of this enzyme class is UDP-L-arabinose 4-epimerase. Other names in common use include uridine ...
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and their ... The systematic name of this enzyme class is cellobiose 2-epimerase. Enzymes like these can produce a more rapid syndrome that ... In enzymology a cellobiose epimerase (EC 5.1.3.11) is an enzyme that catalyzes the chemical reaction cellobiose ⇌ {\ ...
... the 1970 Nobel Prize in Chemistry for his discovery of sugar nucleotides and their role in the biosynthesis of carbohydrates. ... The enzyme UDP-glucose 4-epimerase (EC 5.1.3.2), also known as UDP-galactose 4-epimerase or GALE, is a homodimeric epimerase ... GeneReviews/NCBI/NIH/UW entry on Epimerase Deficiency Galactosemia OMIM entries on Epimerase Deficiency Galactosemia ... Liu Y, Vanhooke JL, Frey PA (June 1996). "UDP-galactose 4-epimerase: NAD+ content and a charge-transfer band associated with ...
... is caused a lack of the enzyme uridine diphosphate galactose-4-epimerase which breaks down a byproduct of galactose. This type ... Carbohydrates account for a major portion of the human diet. These carbohydrates are composed of three principal ... Inborn errors of carbohydrate metabolism are inborn error of metabolism that affect the catabolism and anabolism of ... The metabolic pathway glycolysis is used by cells to break down carbohydrates like glucose (and various other simple sugars) in ...
... specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class ... This also means that the GDP-mannose 3,5-epimerase has three reaction products, namely the main product GDP-L-galactose (C3,5- ... In enzymology, a GDP-mannose 3,5-epimerase (EC 5.1.3.18) is an enzyme that catalyzes the chemical reaction GDP-mannose ⇌ {\ ... Other names in common use include GDP-D-mannose:GDP-L-galactose epimerase, guanosine 5'-diphosphate D-mannose:guanosine 5'- ...
... carbohydrate epimerases MeSH D08.811.399.894.500.700 - UDP-glucose 4-epimerase MeSH D08.811.464.257.050 - acetyl-coa ... carbohydrate dehydrogenases MeSH D08.811.682.047.150.225 - fructuronate reductase MeSH D08.811.682.047.150.250 - galactose ...
... permethylated carbohydrate moiety as "nogalose", more recent data suggest that the nogalose moiety on nogalamycin is methylated ... 5-epimerase) snogH (2,3-dehydratase) snogN (unknown) snogI (aminotransferase) snogG (ketoreductase) snogC (ketoreductase) snogA ...
The enzyme plays an essential role in the carbohydrate metabolism. Mutations in this gene cause ribose 5-phosphate isomerase ... Dickens F, Williamson DH (November 1956). "Pentose phosphate isomerase and epimerase from animal tissues". The Biochemical ... the conversion of carbon dioxide and water into carbohydrates. RPIA is essential in the cycle, as Ru5P generated from R5P is ... RPIA converts Ru5P to R5P which then is converted by ribulose-phosphate 3-epimerase to xylulose-5-phosphate (figure 3). The end ...
When the GNE epimerase kinase does not function correctly in the human body thereby reducing the available ManNAc, it is ... terminal monosaccharides of carbohydrate chains that are attached to glycoproteins and glycolipids (glycans). ManNAc is the ... In the rate-limiting step of the pathway, UDP-GlcNAc is converted into ManNAc by UDP-GlcNAc 2-epimerase, encoded by the ... The UDP-GlcNAc 2-epimerase kinase is the rate limiting step in sialic acid biosynthesis. If the enzyme does not work ...
"The Development of Carbohydrate Chemistry and Biology". Carbohydrate Chemistry, Biology and Medical Applications: 1-28. doi: ... is a congenital disease resulted from altered function of UDP-GlcNAc epimerase . Macular corneal dystrophy: is a congenital ... Carbohydrate chemistry EamA Glycorandomization Glycosyltransferase Nucleotide sugars metabolism Derek Horton (2008). " ...
The sub-categories of isomerases containing racemases, epimerases and cis-trans isomers are examples of enzymes catalyzing the ... Isomerases catalyze reactions across many biological processes, such as in glycolysis and carbohydrate metabolism. Examples of ... Racemases act upon molecules with one chiral carbon for inversion of stereochemistry, whereas epimerases target molecules with ... and epimerases). These isomerases invert stereochemistry at the target chiral carbon. ...
Many ruminant animals form a large amount of 3-carbon propionate during the fermentation of carbohydrates in the rumen. Long- ... However, the D conformation is enzymatically converted into the L conformation by methylmalonyl-CoA epimerase, then it ... but instead use carbohydrates (red blood cells and neurons) or ketone bodies (neurons only). Because many fatty acids are not ...
... and epimerase deficiency with glucose.[citation needed] Accumulated galactose can also undergo an alternative reaction: ... the accumulation of galactose becomes the substrate for enzymes that catalyze the polyol pathway of carbohydrate metabolism. ... Dysmetria Diminished bone density Premature ovarian failure Cataract Galactosemic cataract Other Inborn errors of carbohydrate ...