It has a calcium ion (Ca2+) binding, between the 489th and 500th amino acid, which interacts selectively and non-covalently ... The main functions are the following: To take part in endocytic transport. The EHD-family proteins have been seen to have a ... "EHD Home Page: An ATPase involved in membrane remodelling". www.endocytosis.org. Retrieved 2016-10-15. "Help - Homo_sapiens - ... Its main function is related to endocytic transport. The primary structure of a protein is related to which amino acids a ...

001696 Homo sapiens ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E isoform 1 ATP6V1F NM_004231 Homo sapiens ATPase, H+ ... 018358 CALM1 Calmodulin grasps calcium ions MFSD11 NM_024311 similar to MSFD10 aka TETRAN or tetracycline transporter-like ... 004047 Homo sapiens ATPase, H+ transporting, lysosomal 21kDa, V0 subunit c (ATP6V0B), ATP6V0C NM_001694 Homo sapiens ATPase, H+ ... transporting, lysosomal 14kDa, V1 subunit F (ATP6V1F), ATP6V1G1 NM_004888 Homo sapiens ATPase, H+ transporting, lysosomal 13kDa ...

"Effects of calcium antagonists on serotonin-dependent aggregation and serotonin transport in platelets of patients with ... cinnarizine and flunarizine are potent uncouplers of the vacuolar H+-ATPase in catecholamine storage vesicles". ... It is true that cinnarizine does abolish calcium currents in vestibular hair cells as well; it is just that this only occurs at ... Arab SF, Düwel P, Jüngling E, Westhofen M, Lückhoff A (June 2004). "Inhibition of voltage-gated calcium currents in type II ...

The energy source can be ATP, as is the case for the Na+-K+ ATPase. Alternatively, the energy source can be another chemical ... Exocytosis, fertilization of an egg by sperm activation, and transport of waste products to the lysozome are a few of the many ... One of the critical roles of calcium in the body is regulating membrane fusion. Third, a destabilization must form at one point ... Flippases are members of a larger family of lipid transport molecules that also includes floppases, which transfer lipids in ...

As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+-ATPase pumps in the lens epithelial cells pump ... These are speculated to be involved in lens transport systems linking the surface of the lens to deeper regions. Very similar ... and calcium using transporters/regulators (TRPV channels) results in a flow of nutrients throughout the lens. Glucose is the ... The activity of the Na+/K+-ATPases keeps water and current flowing through the lens from the poles and exiting through the ...

Then the Na/K-ATPase will pump 3 Na out into the peritubular fluid and 2 K into the cell on the non-lumen side of the cell. ... and calcium (Ca2+). Cortical thick ascending limb The cortical thick ascending limb drains urine into the distal convoluted ... ions are reabsorbed from the urine by secondary active transport by a Na-K-Cl cotransporter (NKCC2). The electrical and ... These ions are mostly Na+, Cl−, K+, Ca2+ and HCO3−. The powering force is the Na/K-ATPase on the basolateral membrane which ...

Barnes N, Tsivkovskii R, Tsivkovskaia N, Lutsenko S (2005). "The copper-transporting ATPases, Menkes and Wilson disease ... It is characterized by calcium deposits in a bone at the base of the skull (occipital bone), coarse hair, and loose skin and ... The ATP7A gene encodes a transmembrane protein that transport copper across the cell membranes. It is found throughout the body ... GeneReviews/NCBI/NIH/UW entry on ATP7A-Related Copper Transport Disorders (Articles with short description, Short description ...

... an almost universal finding due to water retention and a shift in intracellular sodium transport from inhibition of Na/K ATPase ... calcium, magnesium, phosphate Glucose Amylase and lipase Arterial blood gas, lactate Blood type and screen Paracetamol ( ... There is also abnormal oxygen transport and utilization. Although delivery of oxygen to the tissues is adequate, there is a ...

Afterward, the Na+ is pumped out of the cell and into the bloodstream by the Na+-K+ ATPase located at the basal membrane and ... This posttranslational modification is necessary for proper folding and transport of the protein to the plasma membrane. ... increased urinary calcium excretion and hyperchloremic metabolic acidosis. However, PHA2 is not caused by mutations within the ... the sodium-chloride symporter transports Na+ and Cl− from the tubular fluid into these cells. ...

... is an ATPase, which means that it is an enzyme that hydrolyzes ATP. This group of enzymes is characterised by their slow ... This calcium is coordinated with six water molecules that are retained by the amino acids Asp11, Asp154, and Gln137. They form ... That is actin could be used to define a circuit along which a load can be transported in a more or less controlled and directed ... It is known that this ATPase is "active", that is, its speed increases by some 40,000 times when the actin forms part of a ...

The main ones are the L-type calcium channel α1-subunit and potassium inward rectifier 2.6; it is therefore classified as a ... Potassium is not in fact lost from the body, but increased Na+/K+-ATPase activity (the enzyme that moves potassium into cells ... The condition has been linked with genetic mutations in genes that code for certain ion channels that transport electrolytes ( ... It is not clear how the described genetic defects increase the Na+/K+-ATPase activity, but it is suspected that the enzyme ...

To transport the Mg2+ ion into the vacuole requires a Mg2+/H+ antiport transporter (such as AtMHX). The H+-ATPases are ... Mg2+ ions close certain types of calcium channels, which conduct positively charged calcium ions into neurons. With an excess ... H+-ATPases pump H+ ions against their concentration gradient to maintain the pH differential that can be used for the transport ... H+-ATPases maintain a constant ΔpH across the plasma membrane and the vacuole membrane. Mg2+ is transported into the vacuole ...

Calcium ions then bind to troponin, which is associated with tropomyosin. Binding causes changes in the shape of troponin and ... There is no evidence for active transport of tropomyosin isoforms to specific locations. Rather, it appears that sorting is the ... Caldesmon is an inhibitor of actinomyosin ATPase and motility, and both actin binding and caldesmon inhibition are greatly ... defects in vesicular transport were observed, and mating of the yeast was poor. When a second yeast gene, TPM2, was deleted, no ...

... has been used in calcium channel blocker toxicity as a rescue therapy for distributive shock unresponsive to ... a drug that inhibits the Na/K-ATPase of cell membranes. Methylene blue has been used as a placebo; physicians would tell their ... Since its reduction potential is similar to that of oxygen and can be reduced by components of the electron transport chain, ... Saha BK, Bonnier A, Chong W (December 2020). "Rapid reversal of vasoplegia with methylene blue in calcium channel blocker ...

... which in turn increases intracellular calcium by passively increasing the action of the sodium-calcium exchanger in the ... Magnesium is needed for the adequate function of the Na+/K+-ATPase pumps in cardiac myocytes, the muscles cells of the heart. A ... Due to magnesium's mobile nature, the plant will first break down chlorophyll in older leaves and transport the Mg to younger ... The increased intracellular calcium gives a positive inotropic effect. Adrenergics, displace magnesium into the cell Cisplatin ...

... allowing the rapid influx of calcium down its electrochemical gradient. Calcium goes on to stimulate exocytosis via binding ... Then, the hexameric ATPase (of the AAA type) called NSF catalyzes the ATP-dependent unfolding of the SNARE proteins and ... These have often been found to be essential to vesicle transport, including Zheng et al 1999's finding regarding Golgi-vacuole ... The influx of calcium is sensed by synaptotagmin 1, which in turn dislodges complexin protein and allows the vesicle to fuse ...

... cation transport proteins MeSH D12.776.157.530.450.250.500 - ca(2+)-transporting atpase MeSH D12.776.157.530.450.250.750 - na ... calcium channels MeSH D12.776.157.530.400.150.400 - calcium channels, l-type MeSH D12.776.157.530.400.150.585 - calcium ... k(+)-exchanging atpase MeSH D12.776.157.530.450.250.812 - organic cation transport proteins MeSH D12.776.157.530.450.250. ... amino acid transport systems, acidic MeSH D12.776.157.530.200.249.500 - amino acid transport system x-ag MeSH D12.776.157.530. ...

Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels ... Deken SL, Beckman ML, Boos L, Quick MW (October 2000). "Transport rates of GABA transporters: regulation by the N-terminal ... Li G, Alexander EA, Schwartz JH (May 2003). "Syntaxin isoform specificity in the regulation of renal H+-ATPase exocytosis". The ... The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the ...

... protein kinase C and calcium/calmodulin-dependent protein kinase II (CaMKII), a kinase integral in controlling calcium ion ... The mitochondrial electron transport chain pathway containing NADH hydrogenase is one potential instigator of these redox ... TopoII catalytic inhibitors bind the N-terminal ATPase subunit of TopoII, preventing the release of the separated DNA strands ... They also inhibit DNA gyrase's ability to bind to DNA instead of inhibiting ATPase activity, and produces several antibiotic ...

Excess glutamate allows high levels of calcium ions (Ca2+) to enter the cell. Ca2+ influx into cells activates a number of ... The Na+-glutamate transporters on neurons and astrocytes can reverse their glutamate transport and start secreting glutamate at ... Li S, Stys PK (2001). "Na(+)-K(+)-ATPase inhibition and depolarization induce glutamate release via reverse Na(+)-dependent ... Another damaging result of excess calcium in the cytosol is the opening of the mitochondrial permeability transition pore, a ...

Atlastin-1 also participates in the generation of tubular ER, whereas spastin is an ATPase linked to several cellular ... lipid synthesis and calcium storage (used in many cell signaling responses). Both mammalian DP1 (for "deleted in polyposis") ... such as signaling and transport processes. The shape of the tubules is given by the reticulons and DP1/Yop1p, whereas their ...

The low concentration of calcium in the cytosol allows calcium ions to function as a second messenger in calcium signaling. ... Molecules taken into the cell by endocytosis or on their way to be secreted can also be transported through the cytosol inside ... Instead, sodium ions are expelled and potassium ions taken up by the Na⁺/K⁺-ATPase, potassium ions then flow down their ... Here, a signal such as a hormone or an action potential opens calcium channel so that calcium floods into the cytosol. This ...

K-ATPase and SR Ca-ATPase inhibitors". Biochimica et Biophysica Acta (BBA) - Biomembranes. 1567 (1-2): 213-220. doi:10.1016/ ... Hogg N, Singh RJ, Kalyanaraman B (March 18, 1996). "The role of glutathione in the transport and catabolism of nitric oxide". ... The vasodilating effects of sulfur dioxide are mediated via ATP-dependent calcium channels and L-type ("dihydropyridine") ... and that those macrocyclic compounds are potent inhibitors of Na+/K+-ATP-ase and Ca-dependent ATP-ase, and have digoxin-like ...

... "for the first discovery of an ion-transporting enzyme, Na+, K+ -ATPase." Adenosine-tetraphosphatase Adenosine methylene ... which is involved in triggering calcium signals by the release of calcium from intracellular stores. This form of signal ... Transporting chemicals out of a cell against a gradient is often associated with ATP hydrolysis. Transport is mediated by ATP ... For every ATP transported out, it costs 1 H+. Producing one ATP costs about 3 H+. Therefore, making and exporting one ATP ...

Instead ions such as sodium can be used as a substitute energy transducer to avoid this pH increase (ATPases are often Na+ ... If the pH is low enough to overcome the natural buffering capacity of the surrounding rocks ('calcium carbonate equivalent' or ... Acidophiles are also able to extrude protons against the pH gradient with unique transport proteins, a process more difficult ... but most require that any H+ taken in must be extruded after use in the electron transport chain (ETC). On the subject of the ...

These energetically free (resistors or conductors, passive transport) or expensive (current sources, active transport) ... Shu, X; Cheng, K; Patel, N; Chen, F; Joseph, E; Tsai, H. J; Chen, J. N (2003). "Na,K-ATPase is essential for embryonic heart ... The vibrating ion-selective microelectrode was first used in 1990 to measure calcium fluxes in various cells and tissues. The ... However, normal ion transport continues in unwounded epithelial cells beyond the wound edge (typically 3.0.CO;2-H. PMID ...

V. A. Tkachuk and his colleagues have also for the first time showed urokinase's ability to transport itself into the core and ... sarcoplasmic ATP-ase" under direction of academician S. E. Severin and A. A. Boldyrev. In 1982 organized a molecular ... Tkachuk and his colleagues discovered that calcium ions get mobilized in platelets under the influence of lipoproteins, which ...

The uptake and transport of sulfate is energy dependent (driven by a proton gradient generated by ATPases) through a proton/ ... Taurine is involved in a variety of physiological processes, including osmoregulation, modulation of calcium signaling, and ... sulfate co-transport. In the shoot the sulfate is unloaded and transported to the chloroplasts where it is reduced. The ... The uptake of sulfate by the roots and its transport to the shoot is strictly controlled and it appears to be one of the ...

... oxides are used in ceramic glazes and calcium/magnesium tungstates are used widely in fluorescent lighting. Crystal ... WtpA is tungsten-binding protein of ABC family of transporters WptB is a permease WtpC is ATPase Because tungsten is a rare ... in Pyrococcus furiosus A wtp system is known to selectively transport tungsten in archaea: ... while scheelite is calcium tungstate (CaWO4). Other tungsten minerals range in their level of abundance from moderate to very ...

... transporting atpase MeSH D12.776.543.585.450.250.750 - na(+)-k(+)-exchanging atpase MeSH D12.776.543.585.450.250.812 - organic ... calcium channels MeSH D12.776.543.550.425.150.400 - calcium channels, l-type MeSH D12.776.543.550.425.150.585 - calcium ... calcium channels MeSH D12.776.543.585.400.150.400 - calcium channels, l-type MeSH D12.776.543.585.400.150.585 - calcium ... vacuolar proton-translocating atpases MeSH D12.776.543.585.450.625.124 - dopamine plasma membrane transport proteins MeSH ...