With her team, she published studies showing the primary role of calcium signalling deregulation in HBV and Hepatitis C virus ( ... Chami M, Benali-Furet NL, Bréchot C, Paterlini-Bréchot P. Impact of calcium signaling in liver carcinogenesis, Med Sci (Paris ... Hepatitis C Virus core protein-induced apoptosis is triggered by ER stress and deregulation of calcium signaling, Oncogene, 31 ... Diagnosis of genetic diseases by calcium signaling and circulating foetal cells" (PDF) (in French). Archived from the original ...

Although not yet entirely understood, the biomineralization process is tightly regulated by calcium signaling. Calcite ... Calcium carbonate and carbon dioxide are produced from calcium and bicarbonate by the following chemical reaction: Ca2+ + 2HCO3 ... During calcification two carbon atoms are taken up and one of them becomes trapped as calcium carbonate. This calcium carbonate ... The primary constituent of coccoliths is calcium carbonate, or chalk. Calcium carbonate is transparent, so the organisms' ...

"Characterization of Calcium-Mediated Intracellular and Intercellular Signaling in the rMC-1 Glial Cell Line". Cellular and ... with a particular focus on modeling the calcium signaling dynamics of astrocyte neural glial cells.[excessive citations] He has ... "Mapping the Spatiotemporal Dynamics of Calcium Signaling in Cellular Neural Networks Using Optical Flow". Annals of Biomedical ... "Catching calcium waves could provide Alzheimer's insights". ScienceDaily. "Self-assembling scaffold for spinal-cord repair: ' ...

Ichas, F.; Mazat, J. P. (1998). "From calcium signaling to cell death: Two conformations for the mitochondrial permeability ... Nicholls, D. G.; Brand, M. D. (1980). "The nature of the calcium ion efflux induced in rat liver mitochondria by the oxidation ... The presence of free radicals, another result of excessive intracellular calcium concentrations, can also cause the MPT pore to ... Gunter, T. E.; Gunter, K. K.; Sheu, S. S.; Gavin, C. E. (1994). "Mitochondrial calcium transport: Physiological and ...

T cells can be activated if membrane potential and calcium signaling are altered, because they are coupled to signal ... The membrane potential and calcium signaling in T lymphocytes are controlled by ion channels. ... If these signal transduction pathways are disrupted, it can prevent the T cells from responding to antigens. This is called ... He, H.; Venema, V.J.; Gu, X.; Venema, R.C.; Marrero, M.B.; Caldwell, R.B. (1999). "Vascular Endothelial Growth Factor Signals ...

The spatial-temporal distribution pattern of calcium is closely related to ubiquitous signaling pathway. Mitochondria actively ... participate in the metabolism of calcium ions to control the function and also modulate the calcium related signaling pathways ... The signal is produced by electrochemical and physical changes in the conducting polymer layer due to changes occurring at the ... In this way, mitochondria can be used to detect the calcium concentration in medium and the detection is very sensitive due to ...

Monoclonal antibodies were used to interrupt calcium signalling between PfRH1 (an RH protein), EBL protein EBA175 and the host ... Gao X, Gunalan K, Yap SS, Preiser PR (2013). "Triggers of key calcium signals during erythrocyte invasion by Plasmodium ... An experimental approach involves preventing the parasite from binding with red blood cells by blocking calcium signalling ...

2010). "Practical aspects of measuring intracellular calcium signals with fluorescent indicators". Methods in Cell Biology. 99 ... Ionomycin is an ionophore and an antibiotic that binds calcium ions (Ca2+) in a ratio 1:1. It is produced by the bacterium ... Its β-diketone and carboxylic acid group form a chelate with calcium. It was extracted in 1978 and the complete structure was ... It is used in research to raise the intracellular calcium level (Ca2+) and as a research tool to understand Ca2+ transport ...

It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an ... Memory CD8+ T lymphocytes (mCTLs) are activated first after infection and then are signaled by CXCR3, IL-12, and CXCL9 by other ... In order to make a powerful secondary infection response, cytokine and chemokine signaling between XCR1+ DCs and NK cells must ... Maghazachi AA (June 1999). "Intracellular signalling pathways induced by chemokines in natural killer cells". Cellular ...

T1 has the original signaling cascade that is involved in the regulation of cell morphology and calcium influx. TrkB is part of ... "Truncated TrkB-T1 mediates neurotrophin-evoked calcium signalling in glia cells". Nature. 426 (6962): 74-78. Bibcode:2003Natur. ... The effect of TrkB/BDNF signalling on AD pathology has been shown to be in part mediated by an increase in δ-secretase levels, ... The full-length isoform (TK+) is a typical tyrosine kinase receptor, and transduces the BDNF signal via Ras-ERK, PI3K, and PLCγ ...

Wang Y, Shibasaki F, Mizuno K (2005). "Calcium signal-induced cofilin dephosphorylation is mediated by Slingshot via ...

Given the importance of calcium signaling in astrocytes, tight regulatory mechanisms for the progression of the spatio-temporal ... In this chronic signaling pathway, p38 is activated as a result of IL-1β signaling, and there is a presence of chemokines that ... Mechanisms of calcium wave propagation include diffusion of calcium ions and IP3 through gap junctions and extracellular ATP ... Verkhratsky A, Orkand RK, Kettenmann H (January 1998). "Glial calcium: homeostasis and signaling function". Physiological ...

In the absence of PDF signaling, all pacemakers still exhibit a daily calcium transient, but two groups are anomalously phase- ... demonstrated that glial-neural signaling may physiologically modulate pdf in a calcium dependent manner. The glial cells, ... It is believed that the reset signal is PDF, because it is M-cell specific and plays a large role in maintaining normal ... Type 1 cells showed that PDF signaled via elevation of intracellular cAMP levels. In contrast, in type 2 cells PDF transiently ...

Suzuki F, Morishima S, Tanaka T, Muramatsu I (Oct 2007). "Snapin, a new regulator of receptor signaling, augments alpha1A- ... adrenoceptor-operated calcium influx through TRPC6". The Journal of Biological Chemistry. 282 (40): 29563-73. doi:10.1074/jbc. ... "Snapin interacts with the N-terminus of regulator of G protein signaling 7". Biochemical and Biophysical Research ... "Functional proteomics mapping of a human signaling pathway". Genome Research. 14 (7): 1324-32. doi:10.1101/gr.2334104. PMC ...

"Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction". Nature ...

"Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction". Nat. Med ... Their activation in these cells causes an increase in intracellular calcium ion, which in turn triggers the opening of ... different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293-301. doi:10.1016/S0092-8674(03)00071-0. PMID ...

... ethylene and calcium signaling". Planta. 227 (2): 453-64. doi:10.1007/s00425-007-0631-y. PMC 2756395. PMID 17924138. (3S,6E)- ...

November 2010). "Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse ... Calcium opens Ca-activated TRP ion channels and leads to depolarization of the cell as well as to release of neurotransmitters ... Their activation in these cells causes an increase in intracellular calcium ion, which in turn triggers the opening of ... TAS2Rs activation produces modulation of a broad range of signal transduction pathways. The Gαgusducin (Gαgus), which belongs ...

The underlying mechanism is that BBP blocks the calcium signaling that is coupled with P2X receptors. Calcium signaling, ...

MT, which acts through the inositol/calcium signaling pathway induces diuretic effects in most amphibians. It was discovered ... Male H. japonica will call to signal their presence to females and to compete with other males. Notes of H. japonica calls are ...

November 2010). "Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse ... Signal transduction of bitter stimuli is accomplished via the α-subunit of gustducin. This G protein subunit activates a taste ... These cells are shown to synapse upon the chorda tympani nerves to send their signals to the brain, although some activation of ... These cells are shown to synapse upon the chorda tympani and glossopharyngeal nerves to send their signals to the brain. The ...

"Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction". Nature ... "Caffeine induces gastric acid secretion via bitter taste signaling in gastric parietal cells". Proceedings of the National ... different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293-301. doi:10.1016/S0092-8674(03)00071-0. PMID ...

PLCγ1 roles are also involved in neuronal actin growth, calcium signaling, and brain development. It is highly regulated by ... It is part of the PIP3 pathway and leads to and increase in calcium in the cells. In neuronal cells, PLCγ1 is highly involved ... This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated ... Meakin SO, MacDonald JI, Gryz EA, Kubu CJ, Verdi JM (April 1999). "The signaling adapter FRS-2 competes with Shc for binding to ...

Beraldo, Flávio H.; Garcia, Célia R.S. (23 August 2007). "Divergent calcium signaling in RBCs from Tropidurus torquatus ( ... The male performs signalling behaviors such as head-bobbing and tail-whipping and exhibits aggressive behaviors such as chasing ...

Calcium signaling in mammalian egg activation and embryo development: the influence of subcellular localization. Molecular ... the sudden rise in calcium concentration occurs because of the influx of calcium ions within the egg. These calcium ions are ... The rise in calcium causes activation of the egg. The egg will then be altered on both a biochemical and morphological level. ... Sperm triggers egg activation by the induction of free calcium ion concentration in the cytoplasm of the egg. This induction ...

Calcium signalling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is ... Calcium/calmodulin-dependent protein kinase type II beta chain is an enzyme that in humans is encoded by the CAMK2B gene. The ... "Entrez Gene: CAMK2B calcium/calmodulin-dependent protein kinase (CaM kinase) II beta". Walikonis RS, Oguni A, Khorosheva EM, ... Yue C, Sanborn BM (2001). "KN-93 inhibition of G protein signaling is independent of the ability of Ca2+/calmodulin-dependent ...

Bram RJ, Crabtree GR (1994). "Calcium signalling in T cells stimulated by a cyclophilin B-binding protein". Nature. 371 (6495 ... Yurchenko V, O'Connor M, Dai WW, Guo H, Toole B, Sherry B, Bukrinsky M (2001). "CD147 is a signaling receptor for cyclophilin B ... Rycyzyn MA, Reilly SC, O'Malley K, Clevenger CV (2001). "Role of cyclophilin B in prolactin signal transduction and nuclear ... a second cyclophilin gene encodes a peptidyl-prolyl isomerase with a signal sequence". Proc Natl Acad Sci U S A. 88 (5): 1903-7 ...

"Sorting of calcium signals at the junctions of endoplasmic reticulum and mitochondria". Cell Calcium. 29 (4): 249-262. doi: ... "calcium-induced-calcium-release" pathways. This can initiate calcium spikes or calcium waves with large changes in the membrane ... So in addition to lower ATP synthesis due to fatty acid oxidation, ATP synthesis is impaired by poor calcium signaling as well ... Hajnóczky G, Csordás G, Das S, Garcia-Perez C, Saotome M, Sinha Roy S, Yi M (2006). "Mitochondrial calcium signalling and cell ...

"Metabotropic glutamate receptors and calcium signalling in dendrites of hippocampal CA1 neurones". Neuropharmacology. 32 (11): ...

... (CAMLG or CAML), also known as calcium-modulating cyclophilin ligand, is a signalling protein ... The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads ... Bram RJ, Crabtree GR (1994). "Calcium signalling in T cells stimulated by a cyclophilin B-binding protein". Nature. 371 (6495 ... This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating ...

Gargus JJ (2009). "Genetic calcium signaling abnormalities in the central nervous system: seizures, migraine, and autism". Ann ... A calciumopathy is a disease caused by disruption to the use of calcium within a cell. To a large extent, a calciumopathy is a ...

... and use calmodulin as a calcium sensor and signal transducer. Calmodulin can also make use of the calcium stores in the ... multifaceted relays to decode calcium signals". Plant Signaling & Behavior. 1 (3): 96-104. doi:10.4161/psb.1.3.2998. PMC ... thus affecting the overall levels of calcium in the cell. Calcium pumps take calcium out of the cytoplasm or store it in the ... Calcium participates in an intracellular signaling system by acting as a diffusible second messenger to the initial stimuli. It ...

"Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy". The ... This increases the flow of calcium ions through the LCCs during depolarization of the cardiomyocyte, increasing calcium levels ... βARKct will bind Gβγ proteins to prevent their interaction with and inhibition of the L-type calcium channels (LCC) present on ... "Preservation of myocardial β-adrenergic receptor signaling delays the development of heart failure after myocardial infarction ...

The non-canonical Wnt signaling can be divided in planar cell polarity (PCP) pathway and Wnt/calcium pathway. It is ... system The Insulin Signaling Pathway The Sonic hedgehog Signaling Pathway The Wnt signaling pathway The JAK-STAT signaling ... The increase of cytosolic calcium also leads to shape change and TxA2 synthesis, leading to signal amplification. The main goal ... Miao, YL; Williams, CJ (November 2012). "Calcium signaling in mammalian egg activation and embryo development: the influence of ...

... importance for calcium signaling and PI3K activity". Immunity. 19 (5): 669-78. doi:10.1016/S1074-7613(03)00297-8. PMID 14614854 ... Phosphatidylinositol-4,5-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways ...

Scholten A, Koch K (2011). "Differential calcium signaling by cone specific guanylate cyclase-activing proteins from the ... This works to alter the calcium sensitivity of the neuron by allowing mutant RETGC-1 to be activated by GCAP at higher calcium ... G protein signaling cascade that is activated by low intracellular calcium levels and inhibited by high intracellular calcium ... this mutation causes extremely high intracellular calcium levels. Calcium, which plays many roles in the cell and is tightly ...

... s are proteins that participate in calcium cell signaling pathways by binding to Ca2+, the calcium ion ... The cellular regulation of calcium is known as calcium homeostasis. Many different calcium-binding proteins exist, with ... Calretinin is another type of Calcium binding protein weighing 29kD. It is involved in cell signaling and shown to exist in ... With their role in signal transduction, calcium-binding proteins contribute to all aspects of the cell's functioning, from ...

Burgoyne RD (2007). "Neuronal calcium sensor proteins: generating diversity in neuronal Ca2+ signalling". Nat. Rev. Neurosci. 8 ... NCS-1 is a calcium sensor, not a calcium buffer (chelator); thus it is a high-affinity, low-capacity, calcium-binding protein. ... Hui K, Fei GH, Saab BJ, Su J, Roder JC, Feng ZP (2007). "Neuronal calcium sensor-1 modulation of optimal calcium level for ... NCS-1 is a member of the neuronal calcium sensor family, a class of EF hand containing calcium-myristoyl-switch proteins. NCS-1 ...

Albright and Wilson Calcium carbide Calcium phosphide Foghorn Lifebuoy "Definition of HOLMES SIGNAL". www.merriam-webster.com. ... They also produced a distress signal, the Deck Flare. They were all charged with calcium carbide, it produced acetylene gas ... For the mast-head distress signal light and the Deck Flare the two plugs were removed by hand and the units placed in a bucket ... In 1875 Holmes obtained a British Patent for a marine audible alarm signal (B.P. 2564 of 1875); and in 1877 he bought, for £80 ...

... an inhibitor of calcium-mediated signal transduction". Clinical Cancer Research. 1 (8): 797-803. PMID 9816048. Bonnefond, M. L ... Carboxyamidotriazole is a calcium channel blocker that blocks voltage-gated and ligand-gated calcium channels and has been ... Calcium channel blockers, Chlorobenzenes, Aromatic ketones, Triazoles, Carboxamides, All stub articles, Antineoplastic and ...

The role of calcium ions in this signal transduction network is therefore important. Calcium Ions also play a large role in ... Once detected, a signal transduction network is activated. The presence of an elicitor causes an influx of Ca2+ ions to be ... Detection of these signals in infected cells leads to an activation of effector-triggered immunity (ETI), a type of innate ... These HAMPs trigger signalling pathways throughout the plant, initiating its defence mechanism and allowing the plant to ...

2016). "Subcellular Imaging of Voltage and Calcium Signals Reveals Neural Processing In Vivo". Cell. 166 (1): 245-257. doi: ... Recently, to compensate for the low signal-to-noise ratio (SNR) due to the poor brightness of GEVI, several denoising methods ... It is a promising optogenetic recording tool that enables exporting electrophysiological signals from cultured cells, live ... calcium imaging, or voltage sensitive dyes. It has subcellular spatial resolution and temporal resolution as low as 0.2 ...

Figure 3: Calcium-induced signal transduction networks mediating neuronal activity-dependent gene expression. Doidge, Norman ( ... This plasticity occurs as a result of changes in gene expression which are triggered by signaling cascades that are activated ... by various signaling molecules (e.g., calcium, dopamine, and glutamate, among many others) during increased neuronal activity. ... It is the variety of proteins and effect of the signal that fundamentally lead to the plasticity feature. Activity-dependent ...