... as well as the more commonly used calcium ionophore A23187. Birefringence microscopy, flow cytometry or fluorescence microscopy ... Once the two meet, a calcium influx occurs, causing a signaling cascade. The cortical granules inside the oocyte then fuse to ...

... down-regulation of gene expression by PMA and calcium ionophore in Jurkat T lymphoma cells". Biochemical and Biophysical ... Flentke GR, Garic A, Amberger E, Hernandez M, Smith SM (July 2011). "Calcium-mediated repression of β-catenin and its ... Soluble inositol-(1,4,5)-trisphosphate triggers calcium to be released from the endoplasmic reticulum. This sudden increase in ... "Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation". Biochimica et ...

The vibrating ion-selective microelectrode was first used in 1990 to measure calcium fluxes in various cells and tissues. The ... Only the specific ion permeates the ionophore, therefore the voltage readout is proportional to the ion concentration in the ... Some ions (such as calcium) and molecules (such as hydrogen peroxide) modulate targeted translocators to produce a current or ... ionophore) is tip-filled into a previously silanized (to prevent leakage) microelectrode. Also, the microelectrode vibrates at ...

... such as calcium ionophore treatment, microinjection of calcium ions, or electrical stimulation. Treatment with cycloheximide, a ... The fertilization event causes intracellular calcium oscillations, and targeted degradation of cyclin B, a regulatory subunit ...

... and a lipid-soluble molecule that transports calcium ions (Ca2+) across the bilayer, also known as calcium ionophore. C1P was ... Inside the cell, S1P can induce calcium release independent of the S1PRs-the mechanism of which remains unknown. To date, the ... Tornquist, K. (February 2003). "Ceramide-1-phosphate increases intracellular free calcium concentrations in thyroid FRTL-5 ... and increase intracellular free calcium concentrations in thyroid cells. C1P also has known roles in vesicular trafficking, ...

"ENHANCEMENT OF NATURAL KILLER CELL ACTIVITY IN HIV-1-INFECTED SUBJECTS BY A MIXTURE OF THE CALCIUM IONOPHORE A23187 AND THE ...

... and did not affect the release of glutamate evoked by a calcium ionophore (ionomycin). A polypeptide (Tx3-3) present in the ... This effect was most likely due to interference with the entry of calcium through voltage-gated calcium channels, because PhTx3 ... The PhTx3 neurotoxin is a broad-spectrum calcium channel blocker that inhibits glutamate release, calcium uptake and also ... We compared the alterations produced by the Tx3-3 with the actions of toxins known to block calcium channels coupled to ...

Calcium Ionophore) Abamectine Abietic acid Acetic acid Acetylcholine Actin Actinomycin D Adenine Adenosmeme Adenosine ...

As calcium is less electropositive than sodium, no calcium will be deposited at the cathode. This method is less expensive than ... like crown ethers and other ionophores, also have a high affinity for the sodium ion; derivatives of the alkalide Na− are ... Calcium is only partially miscible with sodium, and the 1-2% of it dissolved in the sodium obtained from said mixtures can be ... Sodium-calcium alloys are by-products of the electrolytic production of sodium from a binary salt mixture of NaCl-CaCl2 and ...

Calcium is only partially miscible with sodium, and the 1-2% of it dissolved in the sodium obtained from said mixtures can be ... like crown ethers and other ionophores, also have a high affinity for the sodium ion; derivatives of the alkalide Na− are ... Sodium-calcium alloys are by-products of the electrolytic production of sodium from a binary salt mixture of NaCl-CaCl2 and ... Sodium forms alloys with many metals, such as potassium, calcium, lead, and the group 11 and 12 elements. Sodium and potassium ...

Nicholls, D. G.; Brand, M. D. (1980). "The nature of the calcium ion efflux induced in rat liver mitochondria by the oxidation ... Cells exposed to toxic amounts of Ca2+ ionophores also undergo MPT and death by necrosis. While the MPT modulation has been ... The presence of free radicals, another result of excessive intracellular calcium concentrations, can also cause the MPT pore to ... Ichas, F.; Mazat, J. P. (1998). "From calcium signaling to cell death: Two conformations for the mitochondrial permeability ...

... calcium ions are abnormally released. It is because of this that the calcium can become free-roaming which then can trigger ... Ingesting ionophores toxins, such as those found in day blooming jasmine, can cause the heart muscle to become inflamed, which ... When contracting muscles release intercellular calcium, however, if the horse has a predisposed condition that allows for ...

Ca2+ release that then secondarily recruits the IP3Rs or RyRs on the ER by Calcium-induced calcium release (the 'amplifier'). ... The H+ gradient can be eliminated either with H+ ionophores (protonophores) such as nigericin or monensin or by inhibiting the ... Aarhus, R.; Aarhus, R (1995). "A Derivative of NADP Mobilizes Calcium Stores Insensitive to Inositol Trisphosphate and Cyclic ... Patel, S; Docampo, R (May 2010). "Acidic calcium stores open for business: expanding the potential for intracellular Ca2+ ...

When calcium binds to the troponin C, it causes conformational changes which lead to dislocation of troponin I. Afterwards, ... In veterinary medicine, increased cTnI has been noted from myocardial damage after ionophore toxicity in cattle. The high ... These changes alter the myofilament response to calcium, and are of interest in targeting heart failure. Multiple reaction ...

... which releases calcium. This leads to an increase in mitochondrial calcium, dropping its membrane potential. The pore ... a polypeptide from the Red Sea Moses sole with ionophore activity". FEBS Letters. 242 (1): 161-6. doi:10.1016/0014-5793(88) ...

... is a member of a family of naturally occurring cyclic ionophores known as the macrotetrolide antibiotics. The other ... Vishwanath, C. K.; Shamala, N.; Easwaran, K. R. K.; Vijayan, M. (1983). "Structure of nonactin-calcium perchlorate, C40H64O12. ... This ion selectivity is seen in other macrocyclic ligands, such as the cyclic ionophore valinomycin, which is also an ... Due to this property, nonactin is also called "ammonium ionophore". During complexation, the nonactin backbone convolutes into ...

Hammarberg T, Reddy KV, Persson B, Rådmark O (2002). "Calcium binding to 5-lipoxygenase". Adv. Exp. Med. Biol. Advances in ... Rouzer CA, Kargman S (1988). "Translocation of 5-lipoxygenase to the membrane in human leukocytes challenged with ionophore ...

The essential metals that lead interacts with include calcium, iron, and zinc. High levels of calcium and iron tend to provide ... A specific ion-selective electrode has been developed based on the ionophore S,S'-methylenebis (N,N-diisobutyldithiocarbamate ... Acute cases may require the use of disodium calcium edetate, the calcium chelate, and the disodium salt of ... By mimicking calcium, lead can cross the blood-brain barrier. It degrades the myelin sheaths of neurons, reduces their numbers ...

Crosslinking anti-Thy-1 Ab can promote neurite outgrowth which is dependent on G{alpha}i and L- and N-type calcium channel ... Ca2+ ionophore, and diacylglycerol (DAG). As a GPI-anchored protein, Thy-1 is present in the outer leaflet of lipid rafts in ...

... this calcium ion sensing ability is accommodated by an intracellular tail region on Slo-like subunits that form a calcium ion ... Ionophore and anthelmintic activity of PF 1022A, a cyclooctadepsipeptide, are not related - Gesner et al. Willson J; Amliwala K ... Role of calcium in neurotransmitter release evoked by alpha-latrotoxin or hypertonic sucrose - Khvotchev et al. A possible ... Schreiber M, Salkoff L (1997). "A novel calcium-sensing domain in the BK channel". Biophys. J. 73 (3): 1355-63. Bibcode:1997BpJ ...

It also localizes to the acrosomal membrane of the sperm, where it putatively mediates calcium ion transmembrane transport. The ... "The use of anti-VDAC2 antibody for the combined assessment of human sperm acrosome integrity and ionophore A23187-induced ... In mammalian cardiomyocytes, VDAC2 promotes mitochondrial transport of calcium ions in order to power cardiac contractions. In ... Cell Calcium. 49 (2): 136-43. doi:10.1016/j.ceca.2010.12.004. PMID 21241999. Alvira CM, Umesh A, Husted C, Ying L, Hou Y, Lyu ...

Calcium-loading also leads to formation of phosphatidylserine:calcium:phosphate complexes in the plasma membrane mediated in ... Applying ionophores like valinomycin can create electrochemical gradients comparable to the gradients inside living cells. ... Thus, matrix vesicles convey to the extracellular matrix calcium, phosphate, lipids and the annexins which act to nucleate ... During normal calcification, a major influx of calcium and phosphate ions into the cells accompanies cellular apoptosis ( ...

... confirming it acts as an ionophore. Compared to other ionophores, however, bafilomycin has a low affinity for K+. In many ... particularly calcium and amino acids. Additionally, its acidification of endosomes is critical in receptor endocytosis as low ... Bafilomycins have also been found to act as ionophores, transporting potassium K+ across biological membranes and leading to ... Bafilomycin acts as an ionophore, meaning it can transfer K+ ions across biological membranes. Typically, the mitochondrial ...

Similar solutions are formed by the heavy divalent alkaline earth metals calcium, strontium, barium, as well as the divalent ... carbohydrates and ionophore complexes. Lithium naturally only occurs in traces in biological systems and has no known ... Lithium and sodium are typically isolated through electrolysis from their liquid chlorides, with calcium chloride typically ... calcium (1.5%), and aluminium (1.4%); with the remaining 1.2% consisting of trace amounts of other elements. Due to planetary ...

Family 1.A.106 The Calcium Load-activated Calcium Channel (CLAC) Family 1.A.107 The Pore-forming Globin (Globin) Family 1.B.1 ... Family 2.B.14 The Lasalocid A or X-537A Ionophore (Lasalocid) Family 2.B.15 The Tris-thiourea Tripodal-based Chloride Carrier ( ... Family 1.A.87 The Mechanosensitive Calcium Channel (MCA) Family 1.A.88 The Fungal Potassium Channel (F-Kch) Family 1.A.89 The ... Transportan Family 2.B.11 The Calcimycin or A23187 Carrier-type Ionophore Family 2.B.12 The Salinomycin Family 2.B.13 The ...

Calcium plays a large role in the inhibition of enzymes that produce PAF in the denovo pathway of PAF biosynthesis. The ... Using lab rats and mice, he found that ionophore A23187 (a mobile ion carrier that allows the passage of Mn2+, Ca2+ and Mg2+ ... Levy J (Feb 1999). "Abnormal cell calcium homeostasis in type 2 diabetes mellitus: a new look on old disease". Endocrine. 10 (1 ... "The antifungal activity of the Penicillium chrysogenum protein PAF disrupts calcium homeostasis in Neurospora crassa". ...

ISBN 978-3-527-30673-2. Sperelakis, Nicholas; Sperelakis, Nick (January 11, 2012). "Chapter 4: Ionophores in Planar Lipid ... mainly calcium, potassium, sodium, magnesium, iron, and manganese) by weight. Wood also contains sulfur, chlorine, silicon, ...

Mg2+ ions close certain types of calcium channels, which conduct positively charged calcium ions into neurons. With an excess ... Bulychev, A. A.; Vredenberg, W. J. (1976). "Effect of ionophores A-23187 and nigericin on the light induced redistribution of ... Biology and pharmacology of chemical elements Calcium in biology - Use of calcium by organisms Iodine in biology - Use of ... March 2008). "Magnesium, calcium, potassium, and sodium intakes and risk of stroke in male smokers". Arch. Intern. Med. 168 (5 ...