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*  Calcium/calmodulin dependent protein kinase II inhibitor 1
... is a protein that in humans is encoded by the CAMK2N1 gene. GRCh38: ... Calcium/calmodulin dependent protein kinase II inhibitor 1". Retrieved 2017-09-09. Wang C, Li N, Liu X, Zheng Y, Cao X (2008 ... "A novel endogenous human CaMKII inhibitory protein suppresses tumor growth by inducing cell cycle arrest via p27 stabilization ... "CAMK2N1 inhibits prostate cancer progression through androgen receptor-dependent signaling". Oncotarget. 5 (21): 10293-306. doi ...
*  CAMK1D
Calcium/calmodulin-dependent protein kinase ID is a protein in humans that is encoded by the CAMK1D gene on chromosome 10 ( ... This gene encodes a member of the Ca2+/calmodulin-dependent protein kinase 1 subfamily of serine/threonine kinases. The encoded ... Calcium/calmodulin-dependent protein kinase ID". ... protein may be involved in the regulation of granulocyte ...
*  Protein kinase
CaM kinases - containing the calcium/calmodulin-dependent protein kinases. CK1 - containing the casein kinase 1 group. CMGC - ... One very important group of protein kinases are the MAP kinases (acronym from: "mitogen-activated protein kinases"). Important ... Hanks SK, Hunter T (May 1995). "Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain ... A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation ...
*  Marina Picciotto
Picciotto, M. R.; Czernik, A. J.; Nairn, A. C. (15 December 1993). "Calcium/calmodulin-dependent protein kinase I. cDNA cloning ... "Calcium/calmodulin-dependent protein kinase I - cDNA cloning and identification of autophosphorylation site". J. Biol. Chem. ... work with Paul Greengard at Rockefeller University where she cloned the gene for calcium/calmodulin-dependent protein kinase 1 ... "Menthol disrupts nicotine's psychostimulant properties in an age and sex-dependent manner in C57BL/6J mice". Behav Brain Res. ...
*  CASK
This gene is also known by several other names: CMG 2 (CAMGUK protein 2), calcium/calmodulin-dependent serine protein kinase 3 ... "Entrez Gene: CASK Calcium/calmodulin-dependent serine protein kinase (MAGUK family)". Tarpey PS, Smith R, Pleasance E, Whibley ... Zhu ZQ, Wang D, Xiang D, Yuan YX, Wang Y (2014). "Calcium/calmodulin-dependent serine protein kinase is involved in exendin-4- ... "Association of junctional adhesion molecule with calcium/calmodulin-dependent serine protein kinase (CASK/LIN-2) in human ...
*  CAMK2D
... calcium/calmodulin-dependent protein kinase (CaM kinase) II delta". Hook SS, Means AR (2001). "Ca2+/CaM-dependent ... Calcium/calmodulin-dependent protein kinase type II delta chain is an enzyme that in humans is encoded by the CAMK2D gene. The ... product of this gene belongs to the serine/threonine protein kinase family and to the Ca2+/calmodulin-dependent protein kinase ... "Rad and Rad-related GTPases interact with calmodulin and calmodulin-dependent protein kinase II". J. Biol. Chem. 272 (18): ...
*  Ira Tabas
Activation of calcium/calmodulin-dependent protein kinase II in obesity mediates suppression of hepatic insulin signaling". ... and a calcium-induced apoptosis pathway, which involves an ER calcium-release channel IP3R, a calcium-sensitive protein kinase ... Tabas discovered a calcium-IP3R-CaMKII pathway plays a key role in glucagon-mediated excessive hepatic glucose production, ... One notable finding showed a critical link between the PERK / CHOP branch of the stress Unfolded protein response (UPR) ...
*  CAMK2B
... calcium/calmodulin-dependent protein kinase (CaM kinase) II beta". Walikonis RS, Oguni A, Khorosheva EM, Jeng CJ, ... Calcium/calmodulin-dependent protein kinase type II beta chain is an enzyme that in humans is encoded by the CAMK2B gene. The ... Novak G, Seeman P, Tallerico T (2001). "Schizophrenia: elevated mRNA for calcium-calmodulin-dependent protein kinase IIbeta in ... calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic ...
*  CAMK
... 1 calcium/calmodulin-dependent protein kinase I". Yamauchi, Takashi (2005). "Neuronal Ca2+/Calmodulin-Dependent Protein ... domain structure and activation by phosphorylation at threonine-177 by calcium-calmodulin dependent protein kinase I kinase". ... "Human calcium-calmodulin dependent protein kinase I: cDNA cloning, ... CAMK, also written as CaMK, is an abbreviation for the Ca2+/calmodulin-dependent protein kinase class of enzymes. CAMKs are ...
*  CAMK2A
Phosphorylation by cyclic AMP-dependent protein kinase, protein kinase C, and calcium/calmodulin protein kinase; identification ... "Entrez Gene: CAMK2A calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha". Walikonis RS, Oguni A, Khorosheva EM, ... Calcium/calmodulin-dependent protein kinase type II alpha chain (CAMKII╬▒) is an enzyme that in humans is encoded by the CAMK2A ... p39 interact with the alpha-subunit of Ca2+/calmodulin-dependent protein kinase II and alpha-actinin-1 in a calcium-dependent ...
*  Ca2+/calmodulin-dependent protein kinase II
Calcium-Calmodulin Dependent Protein Kinases at the US National Library of Medicine Medical Subject Headings (MeSH) To learn ... Ca2+ /calmodulin-dependent protein kinase II (CaM kinase II or CaMKII) is a serine/threonine-specific protein kinase that is ... Calcium/ calmodulin dependent protein kinase II is also heavily implicated in long-term potentiation (LTP) - the molecular ... "A pivotal role for the multifunctional calcium/calmodulin-dependent protein kinase II in T cells: from activation to ...
*  NMDA receptor
Neuroscience portal Calcium/calmodulin-dependent protein kinases Laube B, Hirai H, Sturgess M, Betz H, Kuhse J (1997). " ... which contain residues that can be directly modified by a series of protein kinases and protein phosphatases, as well as ... "MHC class I immune proteins are critical for hippocampus-dependent memory and gate NMDAR-dependent hippocampal long-term ... Yu XM, Askalan R, Keil GJ, Salter MW (January 1997). "NMDA channel regulation by channel-associated protein tyrosine kinase Src ...
*  Liprin-alpha-1
"Liprinalpha1 degradation by calcium/calmodulin-dependent protein kinase II regulates LAR receptor tyrosine phosphatase ... The protein encoded by this gene is a member of the LAR protein tyrosine phosphatase-interacting protein (liprin) family. ... Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 has been shown to ... "Entrez Gene: PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 ...
*  D1-D2 dopamine receptor heteromer
Ng J, Rashid AJ, So CH, O'Dowd BF, George SR (Jan 2010). "Activation of calcium/calmodulin-dependent protein kinase IIalpha in ... dual functional regulation by G protein-coupled receptor kinase 2". The Journal of Biological Chemistry. 285 (45): 35092-103. ... Hasbi A, Fan T, Alijaniaram M, Nguyen T, Perreault ML, O'Dowd BF, George SR (Dec 2009). "Calcium signaling cascade links ... Verma V, Hasbi A, O'Dowd BF, George SR (Nov 2010). "Dopamine D1-D2 receptor Heteromer-mediated calcium release is desensitized ...
*  Beta-catenin
This sudden increase in cytoplasmic calcium activates Ca2+/calmodulin-dependent protein kinase (CaMKII). Activated CaMKII ... Ren J, Li Y, Kufe D (May 2002). "Protein kinase C delta regulates function of the DF3/MUC1 carcinoma antigen in beta-catenin ... There is one additional requirement: Similar to the mitogen-activated protein kinases (MAPKs), substrates need to associate ... Thus it also requires a "priming kinase" for its activities. In the case of beta-catenin, the most important priming kinase is ...
*  AMPA receptor
"Calcium/calmodulin-dependent protein kinase II phosphorylation drives synapse-associated protein 97 into spines". J. Biol. Chem ... is the influx of calcium through the NMDA receptors and the resultant activation of Ca2+/calmodulin-dependent protein kinase ( ... element-binding protein through a phosphatidylinositol 3-kinase-dependent stimulation of the mitogen-activated protein kinase ... "Long-term potentiation is associated with an increased activity of Ca2+/calmodulin-dependent protein kinase II". J. Biol. Chem ...
*  Active zone
The increase in presynaptic calcium concentration activates calcium-calmodulin-dependent protein kinase (CaMK). CaMK ... The protein ELKS binds to the cell adhesion protein, ╬▓-neurexin, and other proteins within the complex such as Piccolo and ... that cause a local influx of calcium. The increase in calcium is detected by proteins in the active zone and forces vesicles ... It is stabilized by proteins within the active zone and bound to the presynaptic membrane by SNARE proteins. These vesicles are ...
*  CAMKK1
... calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase ... calmodulin-dependent protein kinase I by calmodulin and by Ca2+/calmodulin-dependent protein kinase kinase". J. Biol. Chem. 273 ... calmodulin-dependent protein kinase IV by Ca(2+)-calmodulin-dependent protein kinase Ia kinase. Phosphorylation of threonine ... calmodulin-dependent protein kinase kinase alpha by cAMP-dependent protein kinase: I. Biochemical analysis". J. Biochem. 130 (4 ...
*  CAMK1
Phosphorylation by cyclic AMP-dependent protein kinase, protein kinase C, and calcium/calmodulin protein kinase; identification ... calmodulin-dependent protein kinase I by calmodulin and by Ca2+/calmodulin-dependent protein kinase kinase". J. Biol. Chem. 273 ... Calcium/calmodulin-dependent protein kinase I is expressed in many tissues and is a component of a calmodulin-dependent protein ... Calcium/calmodulin directly activates calcium/calmodulin-dependent protein kinase I by binding to the enzyme and indirectly ...
*  CAMKK2
... and to the Ca++/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent ( ... 2005). "Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase". ... 2005). "Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells ... Calcium/calmodulin-dependent protein kinase kinase 2 is an enzyme that in humans is encoded by the CAMKK2 gene. The product of ...
*  CAMK4
Phosphorylation by cyclic AMP-dependent protein kinase, protein kinase C, and calcium/calmodulin protein kinase; identification ... calmodulin-dependent protein kinase I by calmodulin and by Ca2+/calmodulin-dependent protein kinase kinase". J. Biol. Chem. 273 ... and activation of Ca2+-calmodulin-dependent protein kinase IV by Ca2+-calmodulin-dependent protein kinase Ia kinase. ... 2001). "Human Ca2+/calmodulin-dependent protein kinase kinase beta gene encodes multiple isoforms that display distinct kinase ...
*  MLC1
1999). "Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through ... Membrane protein MLC1 is a protein that in humans is encoded by the MLC1 gene. MLC1 (also called WKL1) is the only human gene ... homology to other proteins suggests that it may be an integral membrane transport protein. Mutations in this gene have been ... The MLC1 protein contains six putative transmembrane domains (S1-S6) and a pore region (P) between S5 and S6. Furthermore, MLC1 ...
*  PPM1F
... a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma ( ... Harvey BP, Banga SS, Ozer HL (2004). "Regulation of the multifunctional Ca2+/calmodulin-dependent protein kinase II by the PP2C ... are Ca2+/calmodulin-dependent protein kinase phosphatases that promote apoptosis". J Biol Chem. 276 (47): 44193-202. doi: ... Protein phosphatase 1F is an enzyme that in humans is encoded by the PPM1F gene. The protein encoded by this gene is a member ...
*  Silent synapse
Ca2+ quickly enters and binds to calmodulin. Calmodulin activates calcium/calmodulin-dependent protein kinase II (CaMKII), ... and calcium ions. Calcium ion entry into the presynaptic terminal causes the presynaptic release of glutamate, which diffuses ... This gives the NMDAR the property of being voltage-dependent, in that it requires strong postsynaptic depolarization to allow ...
*  CAMK2G
"Entrez Gene: CAMK2G calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma". Moyers JS, Bilan PJ, Zhu J, Kahn CR ( ... Calcium/calmodulin-dependent protein kinase type II gamma chain is an enzyme that in humans is encoded by the CAMK2G gene. The ... calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic ... "Localization of the CAMKG gene encoding gamma isoforms of multifunctional calcium/calmodulin-dependent protein kinase (CaM ...
*  Olfactory receptor neuron
The influx of calcium begins a cascade of events within the cell. Calcium first binds to calmodulin to form CaM. CaM will then ... "Molecular cloning and characterization of a calmodulin-dependent phosphodiesterase enriched in olfactory sensory neurons". Proc ... The surface of these cilia is covered with olfactory receptors, a type of G protein-coupled receptor. Each olfactory receptor ... "Phosphorylation and inhibition of olfactory adenylyl cyclase by CaM kinase II in Neurons: a mechanism for attenuation of ...