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*  Catenin
Other catenin, cadherin or cell cycle regulators may also be useful in treating a variety of cancers. While recent studies in ... A tumor cell line with defective δ-catenin, low levels of E-cadherin and poor cell-to-cell adhesion could be restored to normal ... Through the interaction of β-catenin and α-catenin, actin and E-cadherin are linked, providing the cell with a means of stable ... In F9 cells lacking both β-catenin and plakoglobin, very little E-cadherin and α-catenin accumulated at the cell surface. Mice ...
*  Cell adhesion molecule
P-cadherins), neural (N-cadherins), retinal (R-cadherins), brain (B-cadherins and T-cadherins), and muscle (M-cadherins). Many ... Each cadherin exhibits a unique pattern of tissue distribution, such as epithelial (E-cadherins), placental ( ... The classic cadherins (E-, N- and P-) are concentrated at the intermediate cell junctions, which link to the actin filament ... Soncin, F.; Ward, M.C. (2011). "The Function of E-Cadherin in Stem Cell Pluripotency and Self-Renewal". Genes. 2 (1): 229-259. ...
*  CDH17
Cadherin-17 is a protein that in humans is encoded by the CDH17 gene. This gene is a member of the cadherin superfamily, genes ... 2004). "Ksp-cadherin is a functional cell-cell adhesion molecule related to LI-cadherin". Exp. Cell Res. 294 (2): 345-55. doi: ... "Entrez Gene: CDH17 cadherin 17, LI cadherin (liver-intestine)". Gessner R, Tauber R (2001). "Intestinal cell adhesion molecules ... The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane ...
*  Epithelial cell adhesion molecule
Overexpression of EpCAM does not alter the expression level of cadherin but rather decreases the association of the cadherin/ ... Its ability to suppress E-cadherin suggests that EpCAM would promote EMT and tumor metastasis, but its homotypic cell adhesion ... The adhesions mediated by EpCAM are relatively weak, as compared to some other adhesion molecules, such as classic cadherins. ... 1997). "Epithelial cell adhesion molecule (Ep-CAM) modulates cell-cell interactions mediated by classic cadherins". J Cell Biol ...
*  CDH4
Cadherin-4 is a protein that in humans is encoded by the CDH4 gene. This gene is a classical cadherin from the cadherin ... "Entrez Gene: CDH4 cadherin 4, type 1, R-cadherin (retinal)". Brady-Kalnay SM, Mourton T, Nixon JP, Pietz GE, Kinch M, Chen H, ... Kools P, Vanhalst K, van Roy F (Oct 1999). "Assignment of cadherin-4 (R-cadherin, CDH4) to human chromosome band 20q13.3". ... Suzuki S, Sano K, Tanihara H (1991). "Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue". ...
*  Cadherin
... cadherin 9, type 2 (T1-cadherin) CDH10 - cadherin 10, type 2 (T2-cadherin) CDH4 - R-cadherin (retinal) CDH5 - VE-cadherin ( ... N-cadherins are found in neurons CDH12 - cadherin 12, type 2 (N-cadherin 2) CDH3 - P-cadherin (placental): P-cadherins are ... cadherin 7, type 2 CDH8 - cadherin 8, type 2 CDH11 - OB-cadherin (osteoblast) CDH13 - T-cadherin - H-cadherin (heart) CDH15 - M ... KSP-cadherin CDH17 - LI cadherin (liver-intestine) CDH18 - cadherin 18, type 2 CDH19 - cadherin 19, type 2 CDH20 - cadherin 20 ...
*  T-cadherin
... also known as cadherin 13, H-cadherin (heart) (CDH13) is a unique member of cadherin superfamily because it lacks ... T-cadherin expression results in LDL-induced migration of T-cadherin expressing cells compared to control. It is likely that T- ... T-cadherin expression was found to be altered in tumor vessels: in Lewis carcinoma lung metastasis the expression of T-cadherin ... T-cadherin is a GPI-anchored member of cadherin superfamily, which lacks a direct contact with cytoskeleton and therefore is ...
*  VE-cadherin
... is a classical cadherin from the cadherin superfamily and the gene is located in a six-cadherin cluster in a region ... Cadherin 5, type 2 or VE-cadherin (vascular endothelial cadherin) also known as CD144 (Cluster of Differentiation 144), is a ... "Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherin". Arterioscler ... VE-cadherin is indispensable for proper vascular development - there have been two transgenic mouse models of VE-cadherin ...
*  Cadherin cytoplasmic region
In molecular biology, the cadherin cytoplasmic region is a conserved region found at the C-terminus of cadherin proteins. A key ... Nagafuchi A, Takeichi M (December 1988). "Cell binding function of E-cadherin is regulated by the cytoplasmic domain". EMBO J. ... Yap AS, Niessen CM, Gumbiner BM (May 1998). "The juxtamembrane region of the cadherin cytoplasmic tail supports lateral ... of the cadherin. This region induces clustering and also binds to the protein catenin (p120ctn). The cytoplasmic region is ...
*  Fat atypical cadherin 3
... is a protein that in humans is encoded by the FAT3 gene. ENSG00000282908 GRCh38: Ensembl release 89: ... Mitsui, K; Nakajima, D; Ohara, O; Nakayama, M (2002). "Mammalian fat3: A large protein that contains multiple cadherin and EGF- ... FAT atypical cadherin 3". Retrieved 2014-09-11. Berndt, J. D.; Aoyagi, A; Yang, P; Anastas, J. N.; Tang, L; Moon, R. T. (2011 ...
*  Cadherin related family member 3
... (CDHR3), also known as CDH28 or its abbreviation CDHR3, is a protein that in humans is encoded ... Bochkov YA, Watters K, Ashraf S, Griggs TF, Devries MK, Jackson DJ, Palmenberg AC, Gern JE (2015). "Cadherin-related family ... it is believed to be related the function of similar cadherins which function in cell adhesion and cell-to-cell signaling. A ... Cadherin related family member 3". Retrieved 2017-09-05. "Tissue expression of CDHR3 - Summary - The Human Protein Atlas". www. ...
*  Cadherin-catenin complex in learning and memory
Dimerized cadherins readily bind to their presynaptic cadherin partners. Inhibition of N-cadherin binding via blocking ... N-cadherins are transmembrane proteins expressed in the majority of CNS synapses. N-cadherins are most commonly expressed on ... At basal levels of synaptic activity, N-cadherins are largely monomers and are thus weakly adhesive to cadherins located in the ... P120 ctn proteins are thought to either inhibit endocytosis of neural cadherins, or act at the cell surface to control cadherin ...
*  DSC1
2000). "Clustered cadherin genes: a sequence-ready contig for the desmosomal cadherin locus on human chromosome 18". Genomics. ... Garrod DR, Merritt AJ, Nie Z (2003). "Desmosomal cadherins". Curr. Opin. Cell Biol. 14 (5): 537-45. doi:10.1016/S0955-0674(02) ... Jun 1993). "Nomenclature of the desmosomal cadherins". J Cell Biol. 121 (3): 481-3. doi:10.1083/jcb.121.3.481. PMC 2119574 . ... 2000). "Genomic organization and amplification of the human desmosomal cadherin genes DSC1 and DSC3, encoding desmocollin types ...
*  DSC3
Desmocollin-3 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. ... 2001). "Down-regulation of the desmosomal cadherin desmocollin 3 in human breast cancer". Int. J. Oncol. 19 (1): 169-74. doi: ... Jun 1993). "Nomenclature of the desmosomal cadherins". J Cell Biol. 121 (3): 481-3. doi:10.1083/jcb.121.3.481. PMC 2119574 . ... 2000). "Genomic organization and amplification of the human desmosomal cadherin genes DSC1 and DSC3, encoding desmocollin types ...
*  Desmoglein-2
... is required for its high affinity binding to the cytoplasmic domains of E-cadherin and desmosomal cadherin Dsg2, and the tumor ... is required for its high affinity binding to the cytoplasmic domains of E-cadherin and desmosomal cadherin Dsg2, and the tumor ... Bannon LJ, Cabrera BL, Stack MS, Green KJ (Nov 2001). "Isoform-specific differences in the size of desmosomal cadherin/catenin ... Bannon LJ, Cabrera BL, Stack MS, Green KJ (Nov 2001). "Isoform-specific differences in the size of desmosomal cadherin/catenin ...
*  DSC2
Desmosomal cadherins, including the desmocollin family members and desmogleins, are found at desmosome cell-cell junctions and ... Cadherin-like junctional molecules generated by alternative splicing". The Journal of Biological Chemistry. 266 (16): 10438-45 ... King IA, Angst BD, Hunt DM, Kruger M, Arnemann J, Buxton RS (Nov 1997). "Hierarchical expression of desmosomal cadherins during ... Desmocollin-2 is a cadherin-type protein that functions to link adjacent cells together in specialized regions known as ...
*  Masatoshi Takeichi
He is known for his identification of the cadherin class of adhesion molecules. Takeichi was born in Aichi prefecture, Japan ... "The sticky business of discovering cadherins". The Journal of Cell Biology. 170 (4): 514. doi:10.1083/jcb1704fta1. "細胞から個体へ - 脇 ...
*  Hair cell
Müller, U (October 2008). "Cadherins and mechanotransduction by hair cells". Current Opinion in Cell Biology. 20 (5): 557-566. ...
*  Cell junction
Cadherins are calcium-dependent adhesion molecules. Cadherins are extremely important in the process of morphogenesis - fetal ... Cadherin molecules form the actual anchor by attaching to the cytoplasmic plaque, extending through the membrane and binding ... Together with an alpha-beta catenin complex, the cadherin can bind to the microfilaments of the cytoskeleton of the cell. This ... Similarly to desmosomes and hemidesmosomes, their transmembrane anchors are composed of cadherins in those that anchor to other ...
*  Periplakin
Amagai M (1999). "Autoimmunity against desmosomal cadherins in pemphigus". J. Dermatol. Sci. 20 (2): 92-102. doi:10.1016/S0923- ...
*  DCHS1
The encoded protein has a signal peptide, 27 cadherin repeat domains and a unique cytoplasmic region. This particular cadherin ... Protein dachsous homolog 1, also known as protocadherin-16 (PCDH16) or cadherin-19 (CDH19) or cadherin-25 (CDH25) or fibroblast ... cadherin-1 (FIB1), is a protein that in humans is encoded by the DCHS1 gene. This gene is a member of the cadherin superfamily ... 2001). "Identification of three novel non-classical cadherin genes through comprehensive analysis of large cDNAs". Brain Res. ...
*  Plakoglobin
... forms distinct complexes with cadherins and desmosomal cadherins. Plakoglobin is a major cytoplasmic component of ... is required for its high affinity binding to the cytoplasmic domains of E-cadherin and desmosomal cadherin Dsg2, and the tumor ... interacts with E-cadherin and N-cadherin". The Journal of Cell Biology. 118 (3): 671-9. doi:10.1083/jcb.118.3.671. PMC 2289540 ... interacts with E-cadherin and N-cadherin". The Journal of Cell Biology. 118 (3): 671-9. doi:10.1083/jcb.118.3.671. PMC 2289540 ...
*  PCDHGA12
These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of ... Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. ... Matsuyoshi N, Imamura S (1997). "Multiple cadherins are expressed in human fibroblasts". Biochem. Biophys. Res. Commun. 235 (2 ... Yagi T, Takeichi M (2000). "Cadherin superfamily genes: functions, genomic organization, and neurologic diversity". Genes Dev. ...
*  CDH2
N-cadherin, a classical cadherin from the cadherin superfamily, is composed of five extracellular cadherin repeats, a ... N-cadherin, also known as Cadherin-2 (CDH2) or neural cadherin (NCAD) is a protein that in humans is encoded by the CDH2 gene. ... N-cadherin, as well as other cadherins, interact with N-cadherin on an adjacent cell in an anti-parallel conformation, thus ... N-cadherin complexed to catenins has been described as a master regulator of intercalated disc function. N-cadherin appears at ...
*  Embryoid body
Larue, L.; Antos, C.; Butz, S.; Huber, O.; Delmas, V.; Dominis, M.; Kemler, R. (1996). "A role for cadherins in tissue ... Burdsal, C. A.; Damsky, C. H.; Pedersen, R. A. (1993). "The role of E-cadherin and integrins in mesoderm differentiation and ... EBs are formed by the homophilic binding of the Ca2+ dependent adhesion molecule E-cadherin, which is highly expressed on ...