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*  Phase resetting in neurons
link) Jensen, Ole; Lisman, John E. (1996). "Hippocampal CA3 region predicts memory sequences: accounting for the phase ... Jahangiri, A; Durand D. (April 2011). "Phase resetting analysis of high potassium epileptiform activity in CA3 region of the ... Type II Phase Response Curves can have negative and positive regions. Due to this characteristic, Type II PRCs are able to ... full citation needed] Wang, S.G.; Musharoff M; Canavier C; Gasparini S (June 2013). "Hippocampal CA1 pyramidal neurons exhibit ...
*  Place cell
The CA3 hippocampal region is affected differently by decreased plasticity than the CA1 region just discussed. Decreased ... However, while the size of place fields in the hippocampal CA3 region remains the same between young and aged rats, average ... This form of mRNA is decreased in both the CA1 and CA2 hippocampal regions, these reduced levels causing spatial learning ... Place field properties are similar between young and aged rats in the CA1 hippocampal region: rate of firing and spike ...
*  Trisynaptic circuit
Florian, C.; Roullet, P. (2004). "Hippocampal CA3-region is crucial for acquisition and memory consolidation in Morris water ... One study has found that the CA3 plays an essential role in the consolidation of memories when examining CA3 regions using the ... the innermost area of the hippocampal formation, and region CA2. The CA1 is separated from the dentate gyrus by the hippocampal ... The CA3 pyramidal neurons have been analogized as the "pacemaker" of the trisynaptic loop in the generation of hippocampal ...
*  Reconstructive memory
In this way long term episodic functioning moves away from the CA3 region of the Hippocampal formation into the neocortex, ... Among the various regions, the two most active areas during the constructive processes are the medial temporal lobe (including ... effectively freeing up the CA3 area for more initial processing. Studies have also consistently linked the activity of the ...
*  CA3
... a human gene Cornu Ammonis region 3, one of the hippocampal subfields CA-3 may refer to: Buhl-Verville CA-3 Airster Buhl CA-3 ... CA3 may refer to: Carbonic anhydrase III, muscle specific, ... Airsedan CAC CA-3 Wirraway California's 3rd congressional ...
*  Hippocampal memory encoding and retrieval
Kunec, S; Hasselmo, ME; Kopell, N (2005). "Encoding and Retrieval in the CA3 Region of the Hippocampus: A Model of Theta-Phase ... In the Hippocampal Encoding/Retrieval (HIPER) model, episodic encoding is found to take place within the rostral region of the ... GABAergic activity within the septum inhibits certain classes of CA3 cells (a region of the hippocampus), the divide often ... Hippocampal sclerosis involves neural loss and a selective mesial temporal sclerosis (MTS) danger and is likely caused by an ...
*  Hippocampus anatomy
Commissural fibers that originate from CA3 Pyramidal cells go to CA3, CA2 and CA1 regions. Like mossy cells, a single CA3 ... They pass through hippocampal commissures to reach contralateral regions of hippocampus. Hippocampal commissures have dorsal ... Region CA3 combines this input with signals from EC layer II and sends extensive connections within the region and also sends ... Region CA1 receives input from the CA3 subfield, EC layer III and the nucleus reuniens of the thalamus (which project only to ...
*  Hippocampus proper
There are four regions in the hippocampus proper which form a neural circuit. CA1 is the first region in the hippocampal ... CA3 also sends a small set of output fibers to the lateral septum. The region is conventionally divided into three divisions. ... The pyramidal cells in CA3 send some axons back to the dentate gyrus hilus, but they mostly project to regions CA2 and CA1 via ... CA3 has been implicated in a number of working theories on memory and hippocampal learning processes. Slow oscillatory rhythms ...
*  Basket cell
In the CA3 region of the hippocampus, basket cells can often form recurrent inhibition loops with pyramidal cells. Projections ... Hippocampal basket cells target somata and proximal dendrites of pyramidal neurons. Similar to their counterparts in the cortex ... Basket cells are inhibitory GABAergic interneurons of the brain, found throughout different regions of the cortex and ... hippocampal basket cells are also parvalbumin-expressing and fast-spiking. ...
*  Cortical implant
Epilepsy has also been linked to dysfunction in the CA3 region of the hippocampus. A Brain-computer interface (BCI) is a type ... researchers look to replace compromised hippocampal regions and restore function. Treatment for several conditions that impact ... A Nonlinear Model for Hippocampal Cognitive Prosthesis: Memory Facilitation by Hippocampal Ensemble Stimulation. Ieee ... This region is a "neuronal network that coordinates mental processes in the service of explicit intentions or tasks," driving ...
*  Subgranular zone
... marked by the extension of dendrites into the molecular layer of the DG and the growth of axons into the CA3 region, and ... The main function of the SGZ is to carry out hippocampal neurogenesis, the process by which new neurons are bred and ... The subgranular zone (SGZ) is a brain region in the hippocampus where adult neurogenesis occurs. The other major site of adult ... Although more work needs to be done to solidify the relationship between hippocampal neurogenesis and memory, it is clear from ...
*  Schaffer collateral
The Schaffer collateral is located between the CA3 region and CA1 region in the hippocampus. Schaffer collaterals are the axons ... As a part of the hippocampal structures, Schaffer collaterals develop the limbic system, which plays a critical role in the ... connections are made to the CA3 regions of the hippocampus via mossy fibers. CA3 sends the information signals to CA1 pyramidal ... The contralateral CA3 region sends information through Schaffer collateral to the CA1 pyramidal neurons. Plastic changes ...
*  Sharp waves and ripples
They are both produced as the response of CA1 region to inputs from CA3 region. Ripples are only present in the absence of ... The most famous human patient with hippocampal lesion is H.M., whose hippocampus has been removed from both sides of his brain ... Population burst of pyramidal cells in the CA3 region of the hippocampus via CA3 collaterals cause depolarization of pyramidal ... Pyramidal cells of CA3 and CA1 dendritic layer region are important in generating these waves, and they affect the subiculum, ...
*  Episodic-like memory
Information is then directed back to the para-hippocampal region and finally to the same areas of the cerebral cortex that were ... continuing to area CA3, then CA1, and finally through to the subiculum. ... that is projected from nearly all neocortical areas come together onto one or more subdivisions of the para-hippocampal region ... Similarly, hippocampal lesions severely impacted all three components (what, where, and when) suggesting that the hippocampus ...
*  Endocannabinoid system
... mature into granule cells whose axons project to and synapse onto dendrites on the CA3 region. NPs in the hippocampus have been ... Twitchell W, Brown S, Mackie K (1997). "Cannabinoids inhibit N- and P/Q-type calcium channels in cultured rat hippocampal ... In humans, cannabinoid receptors exist in much lower concentration in these regions, which helps explain why cannabinoids ... In the adult brain, the endocannabinoid system facilitates the neurogenesis of hippocampal granule cells. In the subgranular ...
*  Inhibitory postsynaptic potential
When interneurons are activated by metabotropic acetylcholine receptors in the CA1 region of rat hippocampal slices, a theta ... They are dependent on IPSPs and started in either CA3 by muscarinic acetylcholine receptors and within C1 by the activation of ... "Direct depolarization and antidromic action potentials transiently suppress dendritic IPSPs in hippocampal CA1 pyramidal cells ...
*  Hippocampal prosthesis
Next, they had to determine whether a chip could be used as a prosthesis, or implant, for a damaged region in the hippocampus. ... These subregions, CA1 and CA3, interact to create long-term memories. The rats were unable to remember which lever they needed ... successfully tested a hippocampal prosthesis on non-human primates. While the device does not yet consist of a fully ... Sam A. Deadwyler and Robert E. Hampson at Wake Forest Baptist Medical Center, a proof-of-concept hippocampal prosthesis was ...
*  Apical dendrite
CA3 projects Schaffer collaterals to apical dendrites in CA1. Individual pyramidal cells in the CA3 region have burst ... Hippocampal CA3 pyramidal cells have complex dendritic arbors which receive a stratified pattern of synaptic input from a ... The most proximal regions of CA3 pyramidal dendrites receive mossy fiber input exclusively, mid-dendritic regions (strata ... These results are in contrast to the changes in the hippocampal CA3 dendritic arbors, in which only regressive changes were ...
*  Stratum lucidum of hippocampus
Most mossy fiber axons are perpendicular to the CA3 pyramidal region where they project and synapse to either the CA3 pyramidal ... The stratum pyramidale is the third deepest hippocampal layer, and in relation to the stratum lucidum, is located underneath it ... In the CA3 region of the hippocampus, the stratum pyramidale connects with the stratum lucidum by mossy fibers that run though ... This situation is described in the mossy fiber axon connection in the CA3 stratum lucidum region of the hippocampus as is in ...
*  Fascia dentata
As with all regions of the hippocampus, the dentate gyrus also receives GABAergic and cholinergic input from the medial septum ... The fascia dentata is the earliest stage of the hippocampal circuit. Its primary input is the perforant path from the ... neurons are tiny granule cells which give rise to unmyelinated axons called the mossy fibers which project to the hilus and CA3 ...
*  Hippocampus
Chronic stress in the male rat showed dendritic retraction and cell loss in the CA3 region but this was not shown in the female ... The dorsal hippocampus also has more place cells than both the ventral and intermediate hippocampal regions. The intermediate ... Buzsáki G, Chen LS, Gage FH (1990). "Spatial organization of physiological activity in the hippocampal region: relevance to ... Hippocampus animation Pigeon hippocampus (HP) Morphology in four rodent species Main hippocampal regions in marmoset Cell ...
*  Temporal lobe epilepsy
In TLE, there is loss of neurons in region CA1 and CA3 of the hippocampus. There is also damage to mossy cells and inhibitory ... 1993). "Hippocampal neuron loss and memory scores before and after temporal lobe surgery for epilepsy". Archives of Neurology. ... They project into the hilus of the dentate gyrus and stratum lucidum in the CA3 region giving inputs to both excitatory and ... 1974). "The hippocampal-dentate complex in temporal lobe epilepsy". Epilepsia. 15 (1): 55-80. doi:10.1111/j.1528-1157.1974. ...
*  Kainate receptor
"Identification of the kainate receptor subunits underlying modulation of excitatory synaptic transmission in the CA3 region of ... Schmitz D, Mellor J, Nicoll RA (2001). "Presynaptic kainate receptor mediation of frequency facilitation at hippocampal mossy ... This segment then passes through the cell membrane, forming the first of three membrane-spanning regions, M1. The M2 segment ...
*  Septal nuclei
A Functional Circuit from Hippocampal CA3 to Ventral Tegmental Area". Science. 333 (6040): 353-357. doi:10.1126/science.1204622 ... Other axons arising from these cells descend through the medial forebrain bundle to terminate in a region dorsal to the ... The lateral septum is a relay center for connections from the CA3 of the hippocampus to the ventral tegmental area. These ... Other fibers from this region project through the stria medullaris to the medial and lateral habenular nuclei, the paratenial ...
*  Perforant path
CA3) region of the hippocampus. Fibers arising in the lateral portions of the entorhinal cortex show enkephalin ... Remondes, Miguel; Schuman, Erin M. (2004). "Role for a cortical input to hippocampal area CA1 in the consolidation of a long- ... 2011 Science 334:1415) the projection to CA3 and dentate gyrus in mice is primarily from layer II of entorhinal cortex, and ... project to the dentate gyrus and CA3, whereas layer III (and possibly layer V) cells project to CA1 and the subiculum via the ...
*  Transgenerational stress inheritance
Evidence of decreased complexity in the CA1 and CA3 region of the hippocampus in terms of dendritic length and spine density ... Additionally, investigation of post mortem hippocampal tissue indicates decreased levels of neuron-specific glucocorticoid ... Stress can also result in inheritable changes DNA methylation in the promoter regions of the estrogen receptor alpha (ERα), ... Maternal separation and postnatal maternal abuse also increases DNA methylation at regulatory regions of BDNF genes in the ...