Busulfan
Concomitant use of acetaminophen within 72 hours of busulfan use can reduce busulfan clearance (resulting in increased busulfan ... Phenytoin increases hepatic clearance of busulfan (resulting in decreased busulfan AUC). However, clinical studies of busulfan ... Oral bioavailability of busulfan shows a large interindividual variation. Taking busulfan on an empty stomach is recommended to ... Fludarabine + busulfan is a typical example of this use. Toxicity may include interstitial pulmonary fibrosis ("busulfan lung ...
Alkyl sulfonate
Busulfan. Römpp CD 2006, Georg Thieme Verlag 2006 v t e (Articles with short description, Short description matches Wikidata, ...
Ethane dimethanesulfonate
Busulfan Risbridger, GP; Davies, A (June 1994). "Isolation of rat Leydig cells and precursor forms after administration of ...
Chemotherapy
2014). "Association Between Busulfan Exposure and Outcome in Children Receiving Intravenous Busulfan Before Hematopoietic Stem ... Carboplatin: 4 and busulfan dosing rely upon results from blood tests to calculate the optimal dose for each person. Simple ... Chemotherapies with high risk include procarbazine and other alkylating drugs such as cyclophosphamide, ifosfamide, busulfan, ... Nitrogen mustards include mechlorethamine, cyclophosphamide, melphalan, chlorambucil, ifosfamide and busulfan. Nitrosoureas ...
Mannosulfan
Research suggests it is less toxic than the alkyl sulfonate Busulfan. Jeswani G, Paul SD (2017). "Recent Advances in the ...
Gene therapy
April 2019). "Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1". The New England Journal of ...
California Institute for Regenerative Medicine
Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1. In 2017, CIRM awarded $2 million to a ... "Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1". New England Journal of Medicine. 380 (16): ...
Severe combined immunodeficiency
"Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1". New England Journal of Medicine. 380 (16): ...
Bcr-Abl tyrosine-kinase inhibitor
Only cytotoxic drugs such as busulfan, hydroxyurea or interferon-alpha (rIFN-α) were utilized. Even though the first Bcr-Abl TK ...
Astyanax altiparanae
"The effects of temperature and busulfan (Myleran) on the yellowtail tetra Astyanax altiparanae (Pisces, Characiformes) ...
Alkylating antineoplastic agent
Busulfan is an example of a dialkylating agent: it is the methanesulfonate diester of 1,4-butanediol. Methanesulfonate can be ... mustard Melphalan Chlorambucil Ifosfamide Bendamustine Nitrosoureas Carmustine Lomustine Streptozocin Alkyl sulfonates Busulfan ...
Aspen Pharmacare
In a British study, it was found that Aspen's Busulfan, a cancer treatment used by the British National Health Service, had ... tioguanine and busulfan). The commission found that from 2012 to 2019, Aspen had in the EEA persistently earned high profits ...
PAX7
Additionally, mice lacking PAX7 had delayed recovery of spermatogenesis following exposure to busulfan when compared to control ...
Fertility preservation
Chemotherapies with high risk include procarbazine and alkylating drugs such as cyclophosphamide, ifosfamide, busulfan, ...
Dimethylacetamide
... is also used as an excipient in drugs, e.g. in Vumon (teniposide), Busulfex (busulfan) or Amsidine (amsacrine ...
Ectrodactyly
Naruse, Takuji; Takahara, Masatoshi; Takagi, Michiaki; Oberg, Kerby C.; Ogino, Toshihiko (2007). "Busulfan-induced central ...
Total body irradiation
1996). "Pregnancies following high-dose cyclophosphamide with or without high-dose busulfan or total-body irradiation and bone ...
Hematopoietic stem cell transplantation
January 2012). "Autologous stem cell transplantation with thiotepa, busulfan, and cyclophosphamide (TBC) conditioning in ...
Female infertility
... busulfan, melphalan, chlorambucil and chlormethine. Drugs with medium risk include doxorubicin and platinum analogs such as ...
Chemotherapy-induced hyperpigmentation
... cyclophosphamide and busulfan).: 132 Skin lesion James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the ...
Spermatogonial stem cell
took out and isolated SSCs from prepubertal and adult rhesus macaques before treating them with busulfan (an alkylating agent ...
Delcath Systems
... busulfan, capecitabine). University of Pittsburgh Medical Center National Cancer Institute in Bethesda, Maryland Albany Medical ...
Specialty drugs in the United States
... busulfan, capecitabine). Delcath Systems, Inc. (NASDAQ: DCTH) a specialty pharmaceutical and medical device company ...
Treosulfan
Two main studies showed that treosulfan is at least as effective as busulfan, another medicine used to prepare patients for ... of patients given busulfan (with fludarabine). In an additional study in 70 children with blood cancers, 99% of children given ...
Myelodysplastic syndrome
... busulfan, and chlorambucil) or radiation (therapeutic or accidental), or both (e.g., at the time of stem cell transplantation ... MDS after exposure to radiation or alkylating agents such as busulfan, nitrosourea, or procarbazine, typically occurs 3-7 years ...
Teva Pharmaceuticals
Austedo Aviane Azathioprine Azithromycin Baclofen Balziva Bisoprolol Fumarate Bleomycin Budeprion Budesonide Buspirone Busulfan ...
Strimvelis
... the person is treated with busulfan or melphalan to kill as many of the person's existing HSCs to increase the chances of the ...
Pulmonary toxicity
... busulfan, cyclophosphamide, chlorambucil, and nitrosourea (e.g., carmustine). Also, some medicinal drugs used in cardiovascular ...
ATC code L01
Ifosfamide L01AA07 Trofosfamide L01AA08 Prednimustine L01AA09 Bendamustine L01AA10 Melphalan flufenamide L01AB01 Busulfan ...
FLAG (chemotherapy)
In this setting, it is often combined with other agents, such as: Cyclophosphamide (FLAMSA-CYC), and/or Busulfan or treosulfan ...