*  ATPase assay
The Journal of Biological Chemistry. 267 (7): 4854-8. PMID 1347044. ... The ATPase assay is a membrane assay that indirectly measures the activity of efflux transporters. ATP Binding Cassette or ... The ATPase assay is designed to indicate the nature of the interaction between the compound and the transporter. The ATPase ... The ATPase assays can therefore have the potential for determining whether a compound acts as a transporter substrate and/or ...
*  Lowry protein assay
Journal of Biological Chemistry. 193 (1): 265-75. PMID 14907713. A simplification of the protein assay method of Lowry et al. ... The Lowry protein assay is a biochemical assay for determining the total level of protein in a solution. The total protein ... The Bicinchoninic acid assay and the Hartree-Lowry assay are subsequent modifications of the original Lowry procedure. Biuret ... Therefore, cysteine residues in protein probably also contribute to the absorbance seen in the Lowry assay. The result of this ...
*  Ronald M. Evans
... the Salk Institute for Biological Studies". ASSAY and Drug Development Technologies. 1 (6): 749-754. doi:10.1089/ ... is an American professor and biologist at the Salk Institute for Biological Studies in La Jolla, California and a Howard Hughes ...
*  Bradford protein assay
Methods in the Biological Sciences. 395 (1): 108-110. Ninfa, Alexander J. (2010). Fundamental Laboratory Approaches for ... Alternative protein assays include: Ultraviolet-visible spectroscopy Biuret protein assay Lowry protein assay BCA protein assay ... This assay is one of the fastest assays performed on proteins. The total time it takes to set up and complete the assay is ... The Bradford assay, a colorimetric protein assay, is based on an absorbance shift of the dye Coomassie Brilliant Blue G-250. ...
*  Selection and amplification binding assay
Rienhoff HY (1989). "Identification of a transcriptional enhancer in a mouse amyloid gene" (PDF). The Journal of Biological ... Selection and amplification binding assay (SAAB) is a molecular biology technique typically used to find the DNA binding site ... By combining the power of random-sequence selection with pooled sequencing, the SAAB imprint assay makes possible simultaneous ... The Journal of Biological Chemistry. 278 (43): 42247-55. doi:10.1074/jbc.M307386200. PMID 12890668. not sourced [6] not sourced ...
*  Oliver H. Lowry
As of September 2015, his 1951 paper in the Journal of Biological Chemistry describing the protein assay was still the most- ... He devised the Lowry protein assay. Lowry was the youngest of a family of five children. His father was a teacher and later an ... Among all his numerous contributions to biochemistry, Lowry is best known for his development of the Lowry protein assay, used ... Journal of Biological Chemistry. 193 (1): 265-75. PMID 14907713. Noorden R. van; et al. (2014). "The top 100 papers". Nature. ...
*  John Leonora
Later an ELISA method (enzyme linked immunoadsorbent assay) was developed for measuring the parotid hormone titer in biological ...
*  Ungeremine
Biological & Pharmaceutical Bulletin. 27 (11): 1804-9. doi:10.1248/bpb.27.1804. PMID 15516727. Schrader, Kevin K.; Avolio, ... of the acetylcholinesterase inhibitor ungeremine from Nerine bowdenii by preparative HPLC coupled on-line to a flow assay ...
*  Acetylcholinesterase inhibitor
Biological & Pharmaceutical Bulletin. 27 (11): 1804-1809. doi:10.1248/bpb.27.1804. PMID 15516727. [permanent dead link] Rang, H ... of the Acetylcholinesterase Inhibitor Ungeremine from Nerine bowdenii by Preparative HPLC Coupled On-Line to a Flow Assay ...
*  Hsp27
Structure and function of different oligomeric species". The Journal of Biological Chemistry. 274 (21): 14867-74. doi:10.1074/ ... "Detection of protein-protein interactions among lens crystallins in a mammalian two-hybrid system assay". The Journal of ... The Journal of Biological Chemistry. 267 (11): 7718-25. PMID 1560006. Sinsimer KS, Gratacós FM, Knapinska AM, Lu J, Krause CD, ... The Journal of Biological Chemistry. 279 (4): 2394-402. doi:10.1074/jbc.M311324200. PMID 14594798. Irobi J, Van Impe K, Seeman ...
*  CRYAB
The Journal of Biological Chemistry. 275 (2): 1095-104. doi:10.1074/jbc.275.2.1095. PMID 10625651. Kato K, Shinohara H, Goto S ... "Detection of protein-protein interactions among lens crystallins in a mammalian two-hybrid system assay". The Journal of ... The Journal of Biological Chemistry. 267 (11): 7718-25. PMID 1560006. Boelens WC, Croes Y, de Jong WW (January 2001). " ... Biological Chemistry. 277 (6): 4255-60. doi:10.1074/jbc.M110027200. PMID 11700327. Sugiyama Y, Suzuki A, Kishikawa M, Akutsu R ...
*  Quantitative structure-activity relationship
The biological activity of molecules is usually measured in assays to establish the level of inhibition of particular signal ... biological activity can be expressed quantitatively as the concentration of a substance required to give a certain biological ... The QSAR equations can be used to predict biological activities of newer molecules before their synthesis. Examples of machine ... QSAR models first summarize a supposed relationship between chemical structures and biological activity in a data-set of ...
*  Chemical Diversity
Services include identification of a biological target (protein production and assay development) to clinical drug candidates ( ...
*  Michael Marletta
"Nitric-Oxide Synthase Assays", Oxygen radicals in biological systems, Editor Lester Packer, Elsevier, 1994, ISBN 978-0-12- ... He was John G. Searle Professor of Medicinal Chemistry in the College of Pharmacy and Professor of Biological Chemistry at ...
*  Mass spectrometric immunoassay
Assay Immunoassay Immunoscreening SISCAPA Radioimmunoassay Mass Spectrometry Nelson, Randall W.; Krone, Jennifer R.; Bieber, ... Mass spectrometric immunoassay (MSIA) is a method that uses antibodies to analyze protein differences in biological samples. ...
*  TCF3
The Journal of Biological Chemistry. 267 (25): 17498-501. PMID 1325437. Hsu HL, Wadman I, Baer R (Apr 1994). "Formation of in ... "Analysis of the oligomerization of myogenin and E2A products in vivo using a two-hybrid assay system". ... The Journal of Biological Chemistry. 273 (14): 8278-86. doi:10.1074/jbc.273.14.8278. PMID 9525934. Langlands K, Yin X, Anand G ... The Journal of Biological Chemistry. 278 (4): 2370-6. doi:10.1074/jbc.M211464200. PMID 12435739. Maira SM, Wurtz JM, Wasylyk B ...
*  Myogenin
The Journal of Biological Chemistry. 271 (9): 5258-64. doi:10.1074/jbc.271.9.5258. PMID 8617811. Langlands K, Yin X, Anand G, ... "Analysis of the oligomerization of myogenin and E2A products in vivo using a two-hybrid assay system". The Journal of ... The Journal of Biological Chemistry. 271 (9): 5258-64. doi:10.1074/jbc.271.9.5258. PMID 8617811. Chen CM, Kraut N, Groudine M, ... The Journal of Biological Chemistry. 272 (32): 19785-93. doi:10.1074/jbc.272.32.19785. PMID 9242638. Chakraborty T, Martin JF, ...
*  Relative biological effectiveness
Zhu G, Zhang CY (December 2014). "Functional nucleic acid-based sensors for heavy metal ion assays". The Analyst. 139 (24): ... In radiobiology, the relative biological effectiveness (often abbreviated as RBE) is the ratio of biological effectiveness of ... per unit of energy deposited in biological tissues.[citation needed] Different types of radiation have different biological ... The relative biological effectiveness for radiation of type R on a tissue of type T is traditionally defined as the ratio R B E ...
*  Fusarium circinatum
It is based on the biological enrichment of a sample followed by a real-time polymerase chain reaction assay. Many countries ...
*  Hybridization assay
... a hybridization assay is a type of Ligand Binding Assay (LBA) used to quantify nucleic acids in biological matrices. ... The nuclease hybridization assay, also called S1 nuclease cutting assay, is a nuclease protection assay-based hybridization ... Hybridization assays can be in solution or on a solid support such as 96-well plates or labelled beads. Hybridization assays ... The assay is well tolerant to diverse chemistries, as exemplified by the development of a nuclease assay for morpholino ...
*  Enolase
Subsequent analysis using a commercial assay also indicated that ENOblock can inhibit enolase activity in biological contexts, ... Holt A, Wold F (December 1961). "The isolation and characterization of rabbit muscle enolase". The Journal of Biological ... April 2, 2013). "A unique small molecule inhibitor of enolase clarifies its role in fundamental biological processes". ACS ... The Journal of Biological Chemistry. 239: 2464-8. PMID 14235523. Enolase at the US National Library of Medicine Medical Subject ...
*  Gabriel L. Plaa
Xu, Jinghai J.; Dolores Diaz; Peter J. O'Brien (2004). "Applications of cytotoxicity assays and pre-lethal mechanistic assays ... for assessment of human hepatotoxicity potential". Chemico-Biological Interactions. 150 (1): 115-128. doi:10.1016/j.cbi.2004.09 ...
*  Neurosphere
However useful the neurosphere culture has been for biological studies of developmental processes and the functional assay for ... The neurosphere assay, or stemness assay, has been used to confirm that neurospheres contain neural stem cells. Neurospheres ... Since the neurosphere assay's goal is to develop neural stem cells in vitro, the clinical applications of such an achievement ... The predominant use of the neurosphere is in the neurosphere assay. However, in vitro and in vivo environments have shown to ...
*  Pan-assay interference compounds
PAINS tend to nonspecifically react with numerous biological targets rather than specifically affecting one desired target. A ... Pan-assay interference compounds, also referred to as PAINS in the assay or simply PAINS, are chemical compounds that are often ... "PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl ... Capuzzi SJ, Muratov EN, Tropsha A (March 2017). "Phantom PAINS: Problems with the Utility of Alerts for Pan-Assay INterference ...
*  Bioaerosol
Since biological particles are typically analysed using liquid-based assays (PCR, immunoassays, viability assay) it is ... Biological material is impacted and deposited onto an agar lined Petri dish, allowing cultures to develop. Similar to single- ... Separating biological material by aerodynamic diameter is useful due to size ranges being dominated by specific types of ... Bioaerosols (short for biological aerosols) are a subcategory of particles released from terrestrial and marine ecosystems into ...
*  Small molecule
Wienken CJ, Baaske P, Rothbauer U, Braun D, Duhr S (2010). "Protein-binding assays in biological liquids using microscale ... Introduction to Biological and Small Molecule Drug Research and Development: theory and case studies (Kindle ed.). New York: ... Small molecules may be used as research tools to probe biological function as well as leads in the development of new ... Small molecules can have a variety of biological functions or applications, serving as cell signaling molecules, drugs in ...