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*  Antiseptic
Polyhexanide (polyhexamethylene biguanide, PHMB) is an antimicrobial compound suitable for clinical use in critically colonized ...
*  Disinfectant
The biguanide polymer polyaminopropyl biguanide is specifically bactericidal at very low concentrations (10 mg/l). It has a ... Allen MJ, White GF, Morby AP (2006). "The response of Escherichia coli to exposure to the biocide polyhexamethylene biguanide ... Vijayakumar R, Kannan VV, Sandle T, Manoharan C (May 2012). "In vitro Antifungal Efficacy of Biguanides and Quaternary Ammonium ...
*  Polyhexanide
Polyaminopropyl biguanide, a related biguanide disinfectant Ansorg R, Rath PM, Fabry W (2003). "Inhibition of the anti- ... Polyhexanide (polyhexamethylene biguanide, PHMB) is a polymer used as a disinfectant and antiseptic. In dermatological use, it ...
*  Biguanide
... and it is the principal biguanide drug used in pharmacotherapy worldwide. Biguanides do not affect the output of insulin, ... Biguanides also tend to make the cells of the body more willing to absorb glucose already present in the blood stream, and ... Biguanide (/baɪˈɡwɒnaɪd/) is the organic compound with the formula HN(C(NH)NH2)2. It is a colorless solid that dissolves in ... Biguanides were reintroduced into Type 2 diabetes treatment in the late 1950s. Initially phenformin was widely used, but its ...
*  Polyaminopropyl biguanide
... (PAPB) is a disinfectant and a preservative used for disinfection on skin and in cleaning solutions ... Gerit D. Mulder, Joseph P. Cavorsi and Daniel K. Lee (2007). "Polyhexamethylene Biguanide (PHMB): An Addendum to Current ... 2006). "The response of Escherichia coli to exposure to the biocide polyhexamethylene biguanide". Microbiology. 152 (4): 989- ... It is a polymer or oligomer where biguanide functional groups are connected by hexyl hydrocarbon chains, with varying chain ...
*  Metformin
Phenformin, another biguanide, was withdrawn from the market because of an increased risk of lactic acidosis (rate of 40-64 per ... Metformin and other biguanides may antagonize the action of glucagon, thus reducing fasting glucose levels. Metformin also ... Broad interest in metformin was not rekindled until the withdrawal of the other biguanides in the 1970s. Metformin was approved ... Metformin is in the biguanide class. It works by decreasing glucose production by the liver and increasing the insulin ...
*  Karl Slotta
K. H. Slotta; R. Tschesche (1929). "Uber Biguanide. II. Die Blutzuckersenkende Wirkung der Biguanides. Berichte der Deutschen ...
*  Buformin
Biguanides may antagonize the action of glucagon, thus reducing fasting glucose levels. After oral administration of 50 mg of ... Beckmann, R (Mar 1968). "The fate of biguanides in man". Ann N Y Acad Sci. 148 (3): 820-32. doi:10.1111/j.1749-6632.1968. ... The bioavailability of oral buformin and other biguanides is 40%-60%. Binding to plasma proteins is absent or very low. The ... 2011 p 215 Miller, RA; Chu, Q; Xie, J; Foretz, M; Viollet, B; Birnbaum, MJ (Feb 2013). "Biguanides suppress hepatic glucagon ...
*  Glossary of diabetes
Metformin A drug treatment for type 2 diabetes; belongs to a class of drugs called biguanides. First-line pharmacotherapy for ...
*  Antimalarial medication
Proguanil (chloroguanide) is a biguanide; a synthetic derivative of pyrimidine. It was developed in 1945 by a British ...
*  Acanthamoeba keratitis
Lim N, Goh D, Bunce C, Xing W, Fraenkel G, Poole TR, Ficker L (2008). "Comparison of polyhexamethylene biguanide and ... One treatment used is polyhexamethylene biguanide, PHMB. Propamidine isethionate has also shown some effectiveness. Another ...
*  Chlorhexidine
Polyaminopropyl biguanide Polyhexanide Triclosan "Chlorhexidine Gluconate topical". The American Society of Health-System ... Tanzer JM, Slee AM, Kamay BA (1977). "Structural requirements of guanide, biguanide, and bisbiguanide agents for antiplaque ...
*  Alexidine
... is an antimicrobial of the biguanide class. It is also a bisbiguanide. "Antimicrobial substantivity of alexidine and ... Tanzer JM, Slee AM, Kamay BA (1977). "Structural requirements of guanide, biguanide, and bisbiguanide agents for antiplaque ...
*  Phenformin
... is an antidiabetic drug from the biguanide class. It was marketed as DBI by Ciba-Geigy, but was withdrawn from most ... Vladimir Dilman first proposed in 1971 that biguanides like metformin and phenformin may have potential to treat cancer, ...
*  Bisbiguanide
... compounds - Patent 4670592 Tanzer JM, Slee AM, Kamay BA (1977). "Structural requirements of guanide, biguanide, ...
*  Seymour Shapiro
The work for Shapiro's doctoral thesis, "Reaction of Phenyl Biguanide with Esters and Related Compounds", published in JACS in ... We had for some time considered investigating the hypoglycemic properties of our biguanide compounds... Of the more than 260 ... The subject range included blood chemistry, anesthetics, androgens, biguanides, diuretics, indanols, indandiones, triazines and ... biguanide compounds derivatized on the 1 and 1,5 nitrogens, it is unusual that of the 6 to 8 compounds found to be safe and ...
*  Anti-diabetic medication
Biguanides reduce hepatic glucose output and increase uptake of glucose by the periphery, including skeletal muscle. Although ... These include: Sulfonylureas - glimepiride, glipizide, glyburide Biguanides - metformin Thiazolidinediones (Tzd) - pioglitazone ... it must be used with caution in patients with impaired liver or kidney function, metformin, a biguanide, has become the most ...
*  Pancreas
Biguanides such as metformin are also used as part of the treatment along with insulin therapy. The pancreas was first ...
*  Antimicrobial polymer
... synthesis and antibacterial activities of polycations with pendant biguanide groups". Antimicrob. Agents Chemother. 26 (2): 139 ...
*  Fusarium solani
Prevention also includes leaving lenses in polyhexanide biguanide solution overnight to inhibit F. solani. Other risk factors ...
*  Cori cycle
2014;52(2). Sirtori CR, Pasik C. "Re-evaluation of a biguanide, metformin: mechanism of action and tolerability". Pharmacol Res ...
*  Hypoglycemia
... and biguanides. Risk is greater in diabetics who have eaten less than usual, exercised more than usual, or drunk alcohol. Other ...
*  Benzalkonium chloride
Stearalkonium chloride Polyaminopropyl biguanide, an alternative preservative for contact lens solutions ...
*  Benfluorex
Roger, P.; Auclair, J.; Drain, P. (1999). "Addition of Benfluorex to Biguanide Improves Glycemic Control in Obese Non-Insulin- ...
*  Wound bed preparation
Polyhexamethylene biguanide hydrochloride is a fast-acting, broad-spectrum synthetic compound that binds to the cell envelope ... The study group received the Polyhexamethylene biguanide solution (n=59) and the control group received either Ringer's ... A retrospective analysis of wound cleanser clinical efficacy and cost-effectiveness focussed on Polyhexamethylene biguanide ...