N-alpha-acetyltransferase 10
Lim JH, Park JW, Chun YS (15 November 2006). "Human arrest defective 1 acetylates and activates beta-catenin, promoting lung ... Kaidi A, Williams AC, Paraskeva C (February 2007). "Interaction between beta-catenin and HIF-1 promotes cellular adaptation to ... "Hypoxia-inducible factor-1alpha obstructs a Wnt signaling pathway by inhibiting the hARD1-mediated activation of beta-catenin ... However, accumulating evidence have linked Naa10 to various signaling pathways, including Wnt/β-catenin, MAPK, JAK/STAT, and NF ...
CHD8
October 2000). "A novel beta-catenin-binding protein inhibits beta-catenin-dependent Tcf activation and axis formation". The ... February 2002). "Nuclear localization of Duplin, a beta-catenin-binding protein, is essential for its inhibitory activity on ... "CHD8 is an ATP-dependent chromatin remodeling factor that regulates beta-catenin target genes". Molecular and Cellular Biology ... "Early embryonic death in mice lacking the beta-catenin-binding protein Duplin". Molecular and Cellular Biology. 24 (19): 8386- ...
CTNNBIP1
"Axin-independent phosphorylation of APC controls beta-catenin signaling via cytoplasmic retention of beta-catenin". Biochem. ... Beta-catenin-interacting protein 1 is a protein that is encoded in humans by the CTNNBIP1 gene. The protein encoded by this ... 2009). "HINT1 inhibits beta-catenin/TCF4, USF2 and NFkappaB activity in human hepatoma cells". Int. J. Cancer. 124 (7): 1526-34 ... Reichel O, Mayr D, Durst F, Berghaus A (2008). "E-cadherin but not beta-catenin expression is decreased in laryngeal biopsies ...
Planarian
Gurley KA, Rink JC, Sánchez Alvarado A (January 2008). "Beta-catenin defines head versus tail identity during planarian ... to the canonical Wnt/β-Catenin signalling pathway. In 1955, Robert Thompson and James V. McConnell conditioned planarian ...
Frizzled-8
Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human ...
HER2
... increases beta-catenin-E-cadherin association, and decreases beta-catenin-sensitive transcription". Cancer Research. 61 (4): ... Schroeder JA, Adriance MC, McConnell EJ, Thompson MC, Pockaj B, Gendler SJ (June 2002). "ErbB-beta-catenin complexes are ... February 2001). "Geldanamycin abrogates ErbB2 association with proteasome-resistant beta-catenin in melanoma cells, ... "c-erbB-2 gene product directly associates with beta-catenin and plakoglobin". Biochemical and Biophysical Research ...
Frizzled-10
Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this ... beta-catenin - TCF signaling pathway". International Journal of Molecular Medicine. 9 (2): 107-12. doi:10.3892/ijmm.9.2.107. ... "A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals". Proceedings of the National ...
AXIN1
"Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta". ... interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level". Genes Cells. 3 (6): 395-403. doi:10.1046/j. ... interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level". Genes Cells. 3 (6): 395-403. doi:10.1046/j. ... forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin". EMBO J. 17 ( ...
Katherine Jones (academic)
"Mechanism of beta-Catenin and APC-Regulated Transcription at Wnt Target Genes". Grantome. Sierra, Jose; Yoshida, Tomonori; ... Joazeiro, Claudio A.; Jones, Katherine A. (2006-03-01). "The APC tumor suppressor counteracts β-catenin activation and H3K4 ...
RuvB-like 1
Bauer A, Huber O, Kemler R (Dec 1998). "Pontin52, an interaction partner of beta-catenin, binds to the TATA box binding protein ... Bauer A, Huber O, Kemler R (1999). "Pontin52, an interaction partner of beta-catenin, binds to the TATA box binding protein". ... RuvB-like 1 has been shown to interact with: ACTL6A, Beta-catenin, EP400, Myc, and RUVBL2. ENSG00000284901 GRCh38: Ensembl ... "Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity". EMBO J. 19 (22): 6121-30. doi: ...
Abderrahmane Kaidi
Kaidi, Abderrahmane; Williams, Ann Caroline; Paraskeva, Christos (2007). "Interaction between beta-catenin and HIF-1 promotes ...
PPAP2B
"Brachyury is a target gene of the Wnt/beta-catenin signaling pathway". Mechanisms of Development. 91 (1-2): 249-58. doi:10.1016 ... Furthermore, Wnt signaling mediated TCF/LEF-transcription via β-catenin is upregulated in PPAP2B null embryonic stem cells, ...
CSNK1E
... regulation of beta-catenin function". Proceedings of the National Academy of Sciences of the United States of America. 96 (22 ...
MAGED1
Xue B, Wen C, Shi Y, Zhao D, Li C (2005). "Human NRAGE disrupts E-cadherin/beta-catenin regulated homotypic cell-cell adhesion ...
WNT2
Wang HX, Tekpetey FR, Kidder GM (2009). "Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells ... 2009). "Downregulation of Wnt2 and beta-catenin by siRNA suppresses malignant glioma cell growth". Cancer Gene Ther. 16 (4): ... 2009). "The Wnt receptor FZD1 mediates chemoresistance in neuroblastoma through activation of the Wnt/beta-catenin pathway". ... 2007). "Inhibition of Wnt-2 and galectin-3 synergistically destabilizes beta-catenin and induces apoptosis in human colorectal ...
Fusobacterium
and Leptotrichia as well as cancerous gene expression from Beta-catenin signaling. F. nucleatum can be detected in tissues, ... as using anaerobic antibiotics like clindamycin and metronidazole which work when the Fusobacterium can break down the Beta- ...
TMEM158
2006). "Target genes of the WNT/beta-catenin pathway in Wilms tumors". Genes Chromosomes Cancer. 45 (6): 565-74. doi:10.1002/ ...
Frizzled-3
Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. It may play a role in mammalian hair ... Fzd3 in the mouse functions through planar cell polarity signaling instead of the canonical Wnt/beta-catenin pathway. Fzd3 ...
FHL2
"Identification of the LIM protein FHL2 as a coactivator of beta-catenin". J. Biol. Chem. 278 (7): 5188-94. doi:10.1074/jbc. ... "Identification of the LIM protein FHL2 as a coactivator of beta-catenin". J. Biol. Chem. 278 (7): 5188-94. doi:10.1074/jbc. ... "Identification of the LIM protein FHL2 as a coactivator of beta-catenin". The Journal of Biological Chemistry. 278 (7): 5188-94 ... The expression of FHL2 is positively regulated by transforming growth factor beta 1 (TGF-β1) stimulations which induces ...
Casein kinase 2
Gao Y, Wang HY (July 2006). "Casein kinase 2 Is activated and essential for Wnt/beta-catenin signaling". The Journal of ...
Frizzled-4
Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive ... "A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals". Proceedings of the National ... "Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4". Science. 301 (5638): 1391-4. ...
Bronchopulmonary dysplasia
... it has been linked to alterations in the Wnt/beta-catenin pathway. The classic diagnosis of bronchopulmonary dysplasia may be ... "Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities". Signal Transduction and Targeted ...
RUVBL2
"Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity". The EMBO Journal. 19 (22): 6121 ...
TCIM
... beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear ... It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta- ... enhances the Wnt/beta-catenin pathway by relieving antagonistic activity of Chibby". Cancer Research. 66 (2): 723-8. doi: ... correlates with Wnt/beta-catenin target genes and aggressive biological behavior in gastric cancer". Clinical Cancer Research. ...
Cédric Blanpain
Furthermore, he co-authored several papers characterizing the role of Wnt/Beta-Catenin stabilization in precocious bulge stem ... Lowry, WE (2005). "Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells". Genes & Development. 19 ( ...
PTPRF
... increases beta-catenin-E-cadherin association, and decreases beta-catenin-sensitive transcription". Cancer Res. 61 (4): 1671-7 ... PTPRF has been shown to interact with Beta-catenin and liprin-alpha-1. GRCh38: Ensembl release 89: ENSG00000142949 - Ensembl, ... as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin- ... "Geldanamycin abrogates ErbB2 association with proteasome-resistant beta-catenin in melanoma cells, ...
PPP2R5A
Seeling JM, Miller JR, Gil R, Moon RT, White R, Virshup DM (Mar 1999). "Regulation of beta-catenin signaling by the B56 subunit ...
Nicholas Dyson
More recently, Dyson's group has shown that the transcription factor E2F1 is a potent and specific inhibitor of beta-catenin/T- ... "E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8". Nature. 455 (7212): 552-6. Bibcode: ...
WIF1
Simon M, Grandage VL, Linch DC, Khwaja A (2005). "Constitutive activation of the Wnt/beta-catenin signalling pathway in acute ... "Cross-talk between Rac1 GTPase and dysregulated Wnt signaling pathway leads to cellular redistribution of beta-catenin and TCF/ ... inactivation of Wnt inhibitory factor-1 plays an important role in bladder cancer through aberrant canonical Wnt/beta-catenin ...
Frizzled-5
Holmen SL, Robertson SA, Zylstra CR, Williams BO (2005). "Wnt-independent activation of beta-catenin mediated by a Dkk1-Fz5 ... 1998). "A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals". Proc. Natl. Acad. ... "Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin". Dev. Cell. 11 (2): 213-23 ...
Δ-Catenin
Teo JL, Ma H, Nguyen C, Lam C, Kahn M (August 2005). "Specific inhibition of CBP/beta-catenin interaction rescues defects in ... δ-Catenin is a subfamily of catenin proteins with ten armadillo-repeats and includes the proteins catenin delta-1 and catenin ... Like β-catenin and γ-catenin, δ-catenins seem to interact with presenilins. These catenin-presenilin interaction have ... While β-catenin acts as a transcription regulatory protein in the Wnt/TCF pathway, delta-1 catenin has been implicated as a ...