"Interindividual variation in binding of benzo[a]pyrene to DNA in cultured human bronchi". Science. 194 (4269): 1067-1069. doi: ...

Furthermore, her research showed that the effects of benzo(a)pyrene, which is present in tobacco smoke and grilled meats, are ... Shockley studied how pollutants such as benzo(a)pyrene and fluoranthene affect the nervous system. Her research showed that ... Saunders, Crystal R.; Das, Salil K.; Ramesh, Aramandla; Shockley, Dolores C.; Mukherjee, Shyamali (2006). "Benzo(a)pyrene- ... "Modulation of neurotoxic behavior in F-344 rats by temporal disposition of benzo(a)pyrene". Toxicology Letters. 129 (1): 33-45 ...

Zheng Z, Fang JL, Lazarus P (2002). "Glucuronidation: an important mechanism for detoxification of benzo[a]pyrene metabolites ...

An example is benzo(a)pyrene that is metabolized in two steps, oxidation and conjugation. Oxidation produces epoxide ... carcinogenic polycyclic hydrocarbons such as benzo(a)pyrene. These polycyclic hydrocarbons also activate the AH receptor, but ...

A 2012 site study found elevated levels of lead and benzo(a)pyrene in the soil. In 2023, Imperial College's Environmental ...

Some of the chemicals released in this process are benzo(a)pyrene and other polyaromatic hydrocarbons. These fumes pollute the ...

... benzo(a)pyrene, antimony and nickel, as well as aluminum. Copper smelters typically generate cadmium, lead, zinc, arsenic and ...

... pyrene is a constituent of tobacco smoke and is thought to be 30 to 100 times more potent as a carcinogen than benzo[a]pyrene. ... The four dibenzopyrene isomers; dibenzo[a,e]pyrene, dibenzo[a,h]pyrene, dibenzo[a,i]pyrene, dibenzo[a,l]pyrene are included in ... pyrene, dibenzo[a,i]pyrene, dibenzo[a,l]pyrene, and dibenzo[e,l]pyrene. Dibenzopyrenes have been recognized for their suspected ... "Determination of benzo[a]pyrene and dibenzopyrenes in a Chinese coal fly ash certified reference material". Science of the ...

Haseltine, WA; Lo KM; D'Andrea AD (1980). "Preferred Sites of Strand Scission in DNA Modified by anti-Diol Epoxide of Benzo(a) ... Sage, E; Haseltine WA (1984). "High Ratio of Alkali Sensitive Lesions to Total DNA Modification Induced by Benso(a)pyrene diol ... pyrene". Science. 209 (4459): 929-931. Bibcode:1980Sci...209..929H. doi:10.1126/science.7403858. PMID 7403858. Gordon, LK; ...

For example, the polycyclic aromatic hydrocarbon benzo[a]pyrene (BaP), a ligand for AhR, induces its own metabolism and ... benzo[a]pyrene, benzanthracenes and benzoflavones). A range of synthetic ligands have been designed to target the possible ... "DNA adduct formation in precision-cut rat liver and lung slices exposed to benzo[a]pyrene". Toxicological Sciences. 77 (2): 307 ...

For example, aluminum smelters typically generate fluoride, benzo(a)pyrene, antimony and nickel, as well as aluminum. Copper ...

March 1, 1992). "Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA ... intercalation of the covalently attached benzo[a]pyrenyl ring into the helix and displacement of the modified deoxyguanosine". ...

Others such as benzo[a]pyrene diol epoxide and aflatoxin form DNA adducts that induce errors in replication. Nevertheless, due ...

2005). "Alleviation of benzo[a]pyrene-diolepoxide-DNA damage in human lung carcinoma by glutathione S-transferase M2". DNA ...

Zhao Y, Liu HY, Li YQ, Jiang YG (May 2011). "[Effect of miR-542-3p on carcinogenesis induced by anti-benzo(a) pyrene-7,8-diol-9 ...

Toasted bread may contain Benzo[a]pyrene and high levels of acrylamide, a carcinogen generated during the browning process. ...

Potent carcinogens found in cigarette smoke include polycyclic aromatic hydrocarbons (PAH, such as benzo(a)pyrene), benzene, ... benzo[a]pyrene). Charring of food looks like coking and tobacco pyrolysis, and produces carcinogens. There are several ... including benzo[a]pyrene, tobacco-specific nitrosamines such as nitrosonornicotine, and reactive aldehydes such as formaldehyde ...

The capacity of mammalian species to detoxify the carcinogenic chemical benzo(a)pyrene to a water-soluble form also correlates ... "Inverse correlation between species lifespan and capacity of cultured fibroblasts to convert benzo(a)pyrene to water-soluble ...

... and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors". Proceedings of the ...

"MiR-320 and miR-494 affect cell cycles of primary murine bronchial epithelial cells exposed to benzo[a]pyrene". Toxicol in ...

... pyrene (RPF). Although the concentrations measured of benzo[c]fluorene are quite low, when corrected for mutagenicity, benzo[c] ... Other names for benzo[c]fluorene are 7H-benzo[c]fluorene, 3,4-benzofluorene, and NSC 89264. The structure of benzo[c]fluorene ... Benzo[a]fluorene Koganti A, Singh R, Rozett K, Modi N, Goldstein LS, Roy TA, Zhang FJ, Harvey RG, Weyand EH (2000). "7H-benzo[c ... The researchers corrected for the relative mutagenicity of compounds compared to benzo[a]pyrene. The results of this are ...

... anthracene and benzo(a)pyrene. The cleanup goal of benzo(a)anthracene and benzo(a)pyrene was set at a soil concentration of ... The cleanup goal of benzo(a)anthracene and benzo(a)pyrene was achieved. OU2 dealt with building a new Coraopolis Bridge on top ... benzo(a)pyrene, benzo(a)anthracene, dibenz(a,h)antharacene, 4-methylphenol, 2,4-dichlorophenol, 2,4,6-trichlorophenol, dieldrin ... The soil contaminants of concern in 1996 were benzo(a) ...

Cerniglia, C. E.; Mahaffey, W.; Gibson, D. T. (1980). "Fungal oxidation of benzo\a]pyrene: Formation of (−)-trans-7,8-dihydroxy ... fluorene or benzo(a)pyrene. In the case of phenanthrene, C. elegans produces a glucoside conjugate of 1-hydroxyphenanthrene ( ... 8-dihydrobenzo\a]pyrene by Cunninghamella elegans". Biochemical and Biophysical Research Communications. 94 (1): 226-232. doi: ...

Subsequently, in the 1930s the carcinogen component in coal tar was identified as a polyaromatic hydrocarbon (PAH), benzo[a] ... pyrene. Polyaromatic hydrocarbons are also present in soot, which was suggested to be a causative agent of cancer over 150 ...

This enzyme is involved in the toxification of benzo[a]pyrene into (+)-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide, a highly ... Uno, S; Dalton TP; Durkenne S; Curran CP (2004). "Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible ...

... benzo[a]pyrene (BaP), by transforming it to an epoxide. In this reaction, the oxidation of benzo[a]pyrene is catalysed by ... Uno S, Dalton TP, Derkenne S, Curran CP, Miller ML, Shertzer HG, Nebert DW (May 2004). "Oral exposure to benzo[a]pyrene in the ... However, an in vivo experiment with gene-deficient mice has found that the hydroxylation of benzo[a]pyrene by CYP1A1 can have ... and thus inhibits infiltration of ingested benzo[a]pyrene carcinogen into the systemic circulation. CYP1A1 metabolism of ...

Takeshita T, Kanaly RA (2019). "In vitro DNA/RNA Adductomics to Confirm DNA Damage Caused by Benzo[a]pyrene in the Hep G2 Cell ...

"HspA1A facilitates DNA repair in human bronchial epithelial cells exposed to Benzo[a]pyrene and interacts with casein kinase 2 ...

showed that exposure of cells to the carcinogenic benzo(a)pyrene metabolite BPDE caused prompt and sustained upregulation of ... "Adaptive upregulation of DNA repair genes following benzo(a)pyrene diol epoxide protects against cell death at the expense of ...

Weinstein investigated the cancer risks caused by benzo[a]pyrene, which is found in automobile exhaust, barbecued food and ...