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*  Pathogenic Escherichia coli
"Identification of a protein secretory pathway for the secretion of heat-labile enterotoxin by an enterotoxigenic strain of ... Sela S, Nestel D, Pinto R, Nemny-Lavy E, Bar-Joseph M (2005). "Mediterranean fruit fly as a potential vector of bacterial ... Ehrlich G, Hu F, Shen K, Stoodley P, Post J (August 2005). "Bacterial plurality as a general mechanism driving persistence in ... List of strains of Escherichia coli "Escherichia coli O157:H7". CDC Division of Bacterial and Mycotic Diseases. Retrieved 2011- ...
*  List of restriction enzyme cutting sites: Ba-Bc
Protein Eng. 11 (10): 931-5. doi:10.1093/protein/11.10.931. PMID 9862213. Sugisaki H, Maekawa Y, Kanazawa S, Takanami M ( ... A suggested nomenclature for bacterial host modification and restriction systems and their enzymes". J. Mol. Biol. 81 (3): 419- ... Code used to identify the structure of a protein in the PDB database of protein structures. The 3D atomic structure of a ... Jeremy MB, John LT, Lubert S (2002). "3. Protein Structure and Function". Biochemistry. San Francisco: W. H. Freeman. ISBN 0- ...
*  Type three secretion system
Bacterial proteins that need to be secreted pass from the bacterial cytoplasm through the needle directly into the host ... The secreted effector proteins are secreted directly from the bacterial cell into the eukaryotic (host) cell, where they exert ... Pallen M. J.; Bailey C. M.; Beatson S. A. (2006). "Evolutionary links between Flih/Yscl-like proteins from bacterial type iii ... Since the beginning of the 1990s new T3SS proteins are being found in different bacterial species at a steady rate. ...
*  Sequencing
... it is currently much easier to sequence the DNA and infer the protein sequence. Determining part of a protein's amino-acid ... Bacterial genomes can be sequenced in a single run with several times coverage with this technique. This technique was also ... and a range of physical and computational tools used in protein expression and in determining protein structures. In chain ... Derived from the exons these mRNAs are to be later translated to proteins that support particular cellular functions. The ...
*  Rhs toxins
... belong to the polymorphic toxin category of bacterial exotoxins. Rhs proteins are widespread and can be produced by ... Rhs toxins are very large proteins of usually more than 1,500 aminoacids with variable C-terminal toxic domains. Their toxic ... A role in inter-bacterial competition has been demonstrated for the plant pathogen Dickeya dadantii and for the human pathogen ... Ma, Jiale; Sun, Min; Dong, Wenyang; Pan, Zihao; Lu, Chengping; Yao, Huochun (2017-01-01). "PAAR-Rhs proteins harbor various C- ...
*  Anthrax toxin
... the tripartite protein toxin, called anthrax toxin. Anthrax toxin is a mixture of three protein components: (i) protective ... The PA requirement observed in animal-model experiments demonstrates a common paradigm for bacterial toxins, called the A / B ... the synergistic effect of these three proteins leads to cellular death through a cascade of events that allow the proteins to ... Ratcheting up protein translocation with anthrax toxin. Prot Sci. 2012, 21(5):606-24. Abrami, L.; Liu, S.; Cosson, P.; Leppla, ...
*  Type VI secretion system
All characterized bacterial-targeting T6SS proteins act as toxins, either by killing or preventing the growth of target cells. ... T6SS-positive bacterial species prevent T6SS-mediated intoxication towards self and kin cells by producing immunity proteins ... It consists of the proteins TssE, TssF, TssG, and TssK. The baseplate and phage tail-like complex interact in the bacterial ... The T6SS is thought to resemble an inverted phage extending outward from the bacterial cell surface. It consists of 14 proteins ...
*  RTX toxin
The T1SS proteins form a continuous channel spanning both the inner membrane (IM) and outer membrane (OM) of the bacterial cell ... The cyaA operon encodes the five proteins CyaA (RTX toxin), CyaC (CyaA activation protein), and the three T1SS proteins: CyaB ( ... an ABC transporter) CyaD (a membrane fusion protein), and CyaE (an outer membrane protein). The CyaA protein contains an ... The general rtx gene cluster encodes three protein types: the RTX toxin, an RTX activating acyltransferase, and T1SS proteins. ...
*  GA module
... is a protein domain which occurs on the surface of numerous Gram-positive bacterial pathogens. Protein G of group C and G ... The GA module is composed of a left-handed three-helix bundle and is found in a range of bacterial cell surface proteins. GA ... a versatile bacterial protein domain". J. Mol. Biol. 266 (5): 859-65. doi:10.1006/jmbi.1996.0856. PMID 9086265. He Y, Rozak DA ... Proteins containing a GA module include PAB from Peptostreptococcus magnus. Lejon S, Frick IM, Bjorck L, Wikstrom M, Svensson S ...
*  Erythromycin
By binding to the 50s subunit of the bacterial rRNA complex, protein synthesis and subsequent structure and function processes ... It is in the macrolide family and works by decreasing bacterial protein production. Erythromycin was first isolated in 1952 ... Erythromycin bound to proteins in the PDB U.S. Patent 2,653,899 E.E.S. (Erythromycin Ethylsuccinate) Drug Information: Uses, ... Erythromycin is an antibiotic useful for the treatment of a number of bacterial infections. This includes respiratory tract ...
*  Tuberculosis diagnosis
If the patch detects this secreted bacterial protein, the surrounding skin will redden. Two tests are available: the Mantoux ... This skin patch contains antibodies recognizing the secreted bacterial protein MPB-64 passing through the blood capillaries of ... and culture filtrate protein 10 (CFP-10) to stimulate host production of interferon-gamma. Because these antigens are only ...
*  Terri Attwood
Computational prediction of bacterial protein subcellular location and characterisation of transmembrance protein topology. ... Her research concerns protein sequence alignment and protein analysis. Inspired by the creation of PROSITE, Attwood developed a ... As well as being a biocurator she has co-developed tools to align and visualise protein sequences and structures, including ... Mitchell, A. L.; Reich, J. R.; Attwood, T. K. (2003). "PRECIS: Protein reports engineered from concise information in SWISS- ...
*  Transcriptional regulation
Sigma factors are specialized bacterial proteins that bind to RNA polymerases and orchestrate transcription initiation. Sigma ... These mechanisms include control over protein localization or control over whether the protein can bind DNA. An example of this ... "malF - Maltose transport system permease protein MalF - Escherichia coli (strain K12) - malF gene & protein". www.uniprot.org. ... "malG - Maltose transport system permease protein MalG - Escherichia coli (strain K12) - malG gene & protein". www.uniprot.org. ...
*  Bioremediation of radioactive waste
Directed evolution of bacterial proteins related to bioremediation of radionuclides is also a field research. YieF enzyme, for ... Following protein engineering, however, it has also been able to participate in uranyl ion reduction. The use of plants to ... It seems that siderophores on bacterial surface could also facilitate the entry of these elements within the cell as well. ... Bacterial precipitation of metal phosphates". In Valsami-Jones, E. Phosphorus in Environmental Technologies: Principles and ...
*  Protein subcellular localization prediction
... some for human proteins, and some for plant proteins. Methods for the prediction of bacterial localization predictors, and ... Bacterial cell surface and secreted proteins are also of interest for their potential as vaccine candidates or as diagnostic ... For example, secreted proteins and plasma membrane proteins are easily accessible by drug molecules due to their localization ... Gardy JL, Brinkman FS (Oct 2006). "Methods for predicting bacterial protein subcellular localization". Nature Reviews. ...
*  Locus of enterocyte effacement-encoded regulator
The locus of enterocyte effacement-encoded regulator (Ler) is a regulatory protein that controls bacterial pathogenicity of ... wherein a protein product activates a transcript whose protein product activates the transcript of the original protein. Ler ... "Nucleoprotein filament formation is the structural basis for bacterial protein H-NS gene silencing". Scientific Reports. 2: 509 ... The Ler protein also represses its own transcript on the LEE1 operon through DNA looping which prevents RNA polymerase from ...
*  Bromo adjacent homology domain containing 1
"A bacterial protein targets the BAHD1 chromatin complex to stimulate type III interferon response". Science. 331 (6022): 1319- ... Tandem-affinity purification of the BAHD1-associated protein complex in human HEK293 cells identified MIER proteins (MIER1, ... Zhao D, Zhang X, Guan H, Xiong X, Shi X, Deng H, Li H (2016). "The BAH domain of BAHD1 is a histone H3K27me3 reader". Protein ... The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 26 (6): 63-70. doi: ...
*  Phytase
"Kinetic and structural analysis of a bacterial protein tyrosine phosphatase-like myo-inositol polyphosphatase". Protein Science ... Like many PTP superfamily enzymes, the exact biological substrates and roles of bacterial PTP-like phytases have not yet been ... Zhang ZY (2003). "Mechanistic studies on protein tyrosine phosphatases". Prog. Nucleic Acid Res. Mol. Biol. 73: 171-220. doi: ... Puhl AA, Greiner R, Selinger LB (2009). "Stereospecificity of myo-inositol hexakisphosphate hydrolysis by a protein tyrosine ...
*  Ron Shamir
"Identification of protein complexes by comparative analysis of yeast and bacterial protein interaction data". Journal of ... "Quantification of protein half-lives in the budding yeast proteome", Proceedings of the National Academy of Sciences USA, 103 ( ... "Identification of protein complexes" (2016) Elected ISCB Fellow by the International Society for Computational Biology (2012) ...
*  Erythrogenic toxin
... a potent modifier of immunologically important host and bacterial proteins". Biological Chemistry. 392 (12): 1077-88. doi: ... SpeB cleaves degrades multiple proteins through hydrolysis, including cytokines, extracellular matrix proteins and ... a potent modifier of immunologically important host and bacterial proteins". Biological Chemistry. 392 (12): 1077-1088. doi: ... The speB and speJ genes are located in the core bacterial chromosome of all strains of S. pyogenes. However, despite its ...
*  Gut flora
As the microbiome composition changes, so does the composition of bacterial proteins produced in the gut. In adult microbiomes ... The bacterial flora of the small intestine aid in a wide range of intestinal functions. The bacterial flora provide regulatory ... and bacterial 16S rRNA gene sequences are generated with bacterial primers. This form of testing is also often preferable to ... Different bacterial species that appear in gut flora have been shown to be able to drive the immune system to create cytokines ...
*  SpoT
... is a bacterial protein that hydrolizes alarmones, (p)ppGpp, in the bacterial stringent response. Its hydrolase activity is ... In E. coli, SpoT protein consists of 693 amino acids. SpoT belongs to the RSH protein family. It is bifunctional, has both ... The acyl carrier protein (ACP) binds to the TGS domain of SpoT; this binding is probably influenced by the ratio of unacylated ...
*  Sulfate permease
The bacterial proteins vary in size from 434 residues to 573 residues with only a few exceptions. The eukaryotic proteins vary ... Thus, the eukaryotic proteins are usually larger than the prokaryotic homologues. These proteins exhibit 10-13 putative ... Many of these proteins are functionally characterized, and most are inorganic anion uptake transporters or anion:anion exchange ... SLC26 proteins function as anion exchangers and Cl− channels. Ousingsawat et al. (2012) examined the functional interaction ...
*  Rifampicin
... inhibits bacterial RNA polymerase, thus it is commonly used to inhibit the synthesis of host bacterial proteins ... Rifampicin inhibits bacterial DNA-dependent RNA synthesis by inhibiting bacterial DNA-dependent RNA polymerase. Crystal ... and thus preventing synthesis of host bacterial proteins. By this "steric-occlusion" mechanism, rifampicin blocks synthesis of ... The critical functional groups of rifampicin in its inhibitory binding of bacterial RNA polymerase are the four critical ...
*  NACHT domain
It is a predicted nucleoside-triphosphatase (NTPase) domain, which is found in animal, fungal and bacterial proteins. It is ... Its name reflects some of the proteins that contain it: NAIP (NLP family apoptosis inhibitor protein), CIITA (that is, C2TA or ... The NACHT domain is an evolutionarily conserved protein domain. This NTPase domain is found in apoptosis proteins as well as ... Human proteins containing this domain include: CIITA NAIP NLRC3, NLRC4, NLRC5 NLRP1, NLRP2, NLRP3, NLRP4, NLRP5, NLRP6, NLRP7, ...
*  Haemagglutination activity domain
... repetitive bacterial proteins, including many proteins of over 2500 amino acids. A number of the members of this family have ... "Beta-helix model for the filamentous haemagglutinin adhesin of Bordetella pertussis and related bacterial secretory proteins". ... A bacterial adhesin formed as a 50-nm monomeric rigid rod based on a 19-residue repeat motif rich in beta strands and turns". J ... Following this region, proteins typically have regions rich in repeats but may show no homology between the repeats of one ...
*  Benzoyl peroxide/clindamycin
Benzoyl peroxide also kills P. acnes, but by releasing free radical oxygen species, thus oxidizing bacterial proteins. Also, it ... inhibiting bacterial protein synthesis and preventing bacteria from replicating. P. acnes plays a role in the development of ...