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*  Protein precipitation
Protein precipitates left in the salt solution can remain stable for years-protected from proteolysis and bacterial ... P is a protein-protein interaction coefficient, a is a protein-polymer interaction coefficient and x = ( μ i − μ i 0 ) R T {\ ... Protein precipitation is widely used in downstream processing of biological products in order to concentrate proteins and ... Next, proteins undergo a nucleation phase, where submicroscopic sized protein aggregates, or particles, are generated. Growth ...
*  Diguanylate cyclase
It was later noted that numerous bacterial genomes encoded multiple proteins with a GGDEF domain. Pseudomonas aeruginosa PAO1 ... Often, GGDEF domains with DGC activity are found in the same proteins as c-di-GMP-specific phosphodiesterase (PDE) EAL (Glu-Ala ... During the cell cycle of C. crescentus, proteins with GGDEF and EAL domains are separated towards the two distinct poles. The ... D'Argenio, D.A.; Miller, S.I. (2004). "Cyclic di-GMP as a bacterial second messenger". Microbiology. 150 (Pt 8): 2497-502. doi: ...
*  Braun's lipoprotein
The mature protein is 6 kDa in size. Three monomers of Lpp assemble into a coiled-coil trimer. Large amounts of Braun's ... Silhavy TJ, Kahne D, Walker S (2010). "The bacterial cell envelope". Cold Spring Harbor Perspectives in Biology. 2 (5): a000414 ... In E. coli, one third of Lpp proteins form a peptide bond via the side chain of its carboxy-terminal lysine with diaminopimelic ... The gene encoding Braun's lipoprotein initially produces a protein composed of 78 amino acids, which includes a 20 amino acid ...
*  Pathogenicity island
They may be located on a bacterial chromosome or may be transferred within a plasmid or can be found in bacteriophage genomes. ... Regulation genes typically encoded on PAIs include AraC-like proteins and two-component response regulators. PAIs can be ... They can be transferred as a single unit to new bacterial cells, thus conferring virulence to formerly benign strains. PAIs, a ... Groisman E (1996). "Pathogenicity Islands: Bacterial Evolution in Quantum Leaps". Cell. 87: 791-794. doi:10.1016/s0092-8674(00) ...
*  PcrA
"Essential bacterial helicases that counteract the toxicity of recombination proteins". EMBO J. 21 (12): 3137-47. doi:10.1093/ ... The processivity of PcrA is increased in the presence of plasmid replication initiation protein. The structure of the helicase ... "Plasmid replication initiator protein RepD increases the processivity of PcrA DNA helicase". Nucleic Acids Res. 27 (6): 1421-8 ... "DNA helicase activity of PcrA is not required for the displacement of RecA protein from DNA or inhibition of RecA-mediated ...
*  5S ribosomal RNA
Several important proteins which interact with 5S rRNA are listed below. Interaction of 5S rRNA with the La protein prevents ... Translation machineries of mitochondria and plastids (organelles of endosymbiotic bacterial origin), and their bacterial ... Crystallographic studies indicate that 5S rRNA-binding proteins and other proteins of the central protuberance of the LSU plays ... along with numerous associated proteins. In eukaryotes, the LSU contains 5S, 5.8S, and 28S rRNAs and even more proteins. The ...
*  Shiga-like toxin
When the protein is inside the cell, the A subunit interacts with the ribosomes to inactivate them. The A subunit of Shiga ... which drives formation of inward membrane tubules for the bacterial uptake into the cell. These tubules are essential for ... The toxin is a multisubunit protein made up of one molecule of A subunit (32,000 molecular weight) responsible for the toxic ... action of the protein, and five molecules of the B subunit (7,700 molecular weight) responsible for binding to a specific cell ...
*  Terpene synthase N terminal domain
Sequences containing this protein domain belong to the terpene synthase family. It has been suggested that this gene family be ... cDNA isolation, characterization, and bacterial expression of a bifunctional diterpene cyclase in fungal gibberellin ... This entry will focus on the N terminal domain of the TPS protein. Terpenes synthases have a role in producing important ... In molecular biology, this protein domain belongs to the terpene synthase family (TPS). Its role is to synthesize terpenes ...
*  Cry6Aa
... is a toxic crystal protein generated by the bacterial family Bacillus thuringiensis during sporulation. This protein is ... Cry6Aa proteins are unrelated to other insecticidal crystal proteins in primary amino acid structure. The protein is rod-shaped ... Since Cry6Aa proteins function differently than other Cry proteins, they are combined with other proteins to decrease the ... The corresponding B. thuringiensis gene, cry6aa, is located on bacterial plasmids. Along with several other Cry protein genes, ...
*  LdrD-RdlD toxin-antitoxin system
RdlD RNA (regulator detected in LDR-D) is a family of small non-coding RNAs which repress the protein LdrD in a type I toxin- ... Van Melderen L, Saavedra De Bast M (March 2009). "Bacterial toxin-antitoxin systems: more than selfish entities?". PLoS Genet. ... The LdrD protein causes growth inhibition, loss of cell viability, nucleoid condensation and alteration in purine metabolism ... Fozo EM, Hemm MR, Storz G (December 2008). "Small toxic proteins and the antisense RNAs that repress them". Microbiol. Mol. ...
*  Homologous recombination
"Structural relationship of bacterial RecA proteins to recombination proteins from bacteriophage T4 and yeast". Science. 259 ( ... RecA protein binds to this strand and is either aided by the RecF, RecO, and RecR proteins or stabilized by them. The RecA ... The proteins of the RecA recombinase family of proteins are thought to be descended from a common ancestral recombinase. The ... The proteins generally share a long conserved region known as the RecA/Rad51 domain. Within this protein domain are two ...
*  Fatty acid synthase
In some cancer cell lines, this protein has been found to be fused with estrogen receptor alpha (ER-alpha), in which the N- ... Jenke-Kodama H, Sandmann A, Müller R, Dittmann E (October 2005). "Evolutionary implications of bacterial polyketide synthases ... Fatty acid synthase is a multi-enzyme protein that catalyzes fatty acid synthesis. It is not a single enzyme but a whole ... Mammalian FAS consists of a homodimer of two identical protein subunits, in which three catalytic domains in the N-terminal ...
*  Trp operon
... trp R has a promoter where RNA polymerase binds and synthesizes mRNA for a regulatory protein. The protein that is synthesized ... 394-402 Yanofsky, C (1981). "Attenuation in the control of expression of bacterial operons". Nature. 289: 751-758. doi:10.1038/ ... In the lac operon, allolactose binds to the repressor protein, allowing gene transcription, while in the trp operon, tryptophan ... Within the operon's regulatory sequence, the operator is blocked by the repressor protein in the presence of tryptophan ( ...
*  MMACHC
The C-terminal region of the product of the MMACHC gene is similar to TonB, a bacterial protein involved in energy transduction ... Methylmalonic aciduria and homocystinuria type C protein (MMACHC) is a protein that in humans is encoded by the MMACHC gene. ... 2009). "A human vitamin B12 trafficking protein uses glutathione transferase activity for processing alkylcobalamins". J. Biol ...
*  T-A hol family
Homologues include thousands of diverse phage and bacterial proteins between 80 and 140 amino acyl residues (aas) in length ... Phage-like transmembrane protein', 'YeaQ protein', etc. in the NCBI protein database. As of early 2016, they remain ... These proteins are related to the RDD family (TC# 9.B.45) in the conserved domain database. A representative list of proteins ... Wang, I. N.; Smith, D. L.; Young, R. (2000-01-01). "Holins: the protein clocks of bacteriophage infections". Annual Review of ...
*  Phosphate-selective porin
... s are a family of outer bacterial membrane proteins. These are anion-specific porins, the binding site ...
*  Allergy
Emanuelsson C, Spangfort MD; Spangfort (2007). "Allergens as eukaryotic proteins lacking bacterial homologues". Mol. Immunol. ... Milk-protein allergies are most common in children. Approximately 60% of milk-protein reactions are immunoglobulin E-mediated, ... and chestnut occurs because latex proteins are structurally homologous with some other plant proteins. About 10% of people ... Certain microbe-sensing proteins, known as Toll-like receptors, found on the surface of cells in the body are also thought to ...
*  Mycoplasma pneumoniae
... which inhibit bacterial protein synthesis by binding 23S rRNA. Administration of antibiotics has been proven to reduce the ... The P1 adhesin (trypsin-sensitive protein) is a 120 kDa protein highly clustered on the surface of the attachment organelle tip ... Loss of proteins in the cytoskeleton involved in the localization of P1 in the tip structure, such as HMW1-HMW3, also cause ... Another protein considered to play an important role in cytadherence is P30, as M. pneumoniae cells with mutations in this ...
*  Suppressor of fused Sufu protein N terminal domain
2010). "The crystal structure of a bacterial Sufu-like protein defines a novel group of bacterial proteins that are similar to ... In eukaryotic Sufu, an additional domain is found at the C terminus of the protein. This protein domain also binds to the C- ... In molecular biology, the protein domain suppressor of fused protein (Sufu) has an important role in the cell. The Sufu is ... This particular article focuses on the N-terminal domain of the Sufu protein. Sufu has also been found to have a crucial role ...
*  Phi value analysis
Alan Fersht pioneered the phi value analysis method by first applying it to the small bacterial protein barnase. In conjunction ... 2000). Transition states in protein folding. In Mechanisms of Protein Folding 2nd ed, editor RH Pain. Oxford University Press. ... the folded state and the transition state for the wild-type and mutant proteins. Typically, a high fraction of the protein's ... Theory of protein engineering analysis of stability and pathway of protein folding". J Mol Biol. 224: 771-82. doi:10.1016/0022- ...
*  NMDA receptor
This has revealed a common fold with amino acid-binding bacterial proteins and with the glutamate-binding module of AMPA- ... which contain residues that can be directly modified by a series of protein kinases and protein phosphatases, as well as ... Two specific proteins have been identified as a major pathway responsible for these different cellular responses ERK1/2, and ... Proteins of the major histocompatibility complex class I are endogenous negative regulators of NMDAR-mediated currents in the ...
*  Representative sequences
Bern, Marshall; Goldberg, David (November 2, 2004). "Automatic selection of representative proteins for bacterial phylogeny". ... Protein sequences can provide data about the biological function and evolution of proteins and protein domains. Grouping and ... Representative sequences are short regions within protein sequences that can be used to approximate the evolutionary ... Representative sequences are contiguous subsequences (typically 300 residues) from ubiquitous, conserved proteins, such that ...
*  Terrabacteria
Bern, M; Goldberg, D (2005). "Automatic selection of representative proteins for bacterial phylogeny". BMC Evolutionary Biology ...
*  Human leukocyte antigen
The image off to the side shows a piece of a poisonous bacterial protein (SEI peptide) bound within the binding cleft portion ... MHC class I proteins associate with β2-microglobulin, which unlike the HLA proteins is encoded by a gene on chromosome 15. HLAs ... Through a similar process, proteins (both native and foreign, such as the proteins of virus) produced inside most cells are ... proteins in humans. These cell-surface proteins are responsible for the regulation of the immune system in humans. The HLA gene ...
*  Andreas Matouschek
... a bacterial RNAse used in many protein folding studies. Development of phi value analysis in combination with extensive protein ... of phi value analysis in combination with protein engineering in order to study the transition state of the bacterial protein ... "Mapping the transition state and pathway of protein folding by protein engineering". Nature. 340: 122-6. doi:10.1038/340122a0. ... In subsequent postdoctoral work at the University of Basel, he studied how mitochondria refold proteins after importing them. ...
*  NLRP12
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as ... "NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial ... NACHT, LRR and PYD domains-containing protein 12 is a protein that in humans is encoded by the NLRP12 gene. ... 2007). "Heat shock protein 90 associates with monarch-1 and regulates its ability to promote degradation of NF-kappaB-inducing ...
*  B1 domain
In molecular biology, the protein domain b1 refers to the domain b1 of Protein L. L is a bacterial protein with immunoglobulin ... These repeats have been found to be responsible for the interaction of protein L with Ig light chains. N-terminus domain ... Kastern W, Sjöbring U, Björck L (June 1992). "Structure of peptostreptococcal protein L and identification of a repeated ...