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*  Zinc finger nuclease
Chimeric nuclease Genome editing Gene targeting Zinc finger protein Zinc finger chimera Protein engineering Genome engineering ... A promising new method to select novel zinc-finger arrays utilizes a bacterial two-hybrid system and has been dubbed "OPEN" by ... Since the protein must be expressed only transiently, however, the time over which a response may develop is short. Liu et al. ... Several different protein engineering techniques have been employed to improve both the activity and specificity of the ...
*  RecBCD
The RecA protein is then actively loaded onto the 3' tail by RecBCD. At some undetermined point RecBCD dissociates from the DNA ... Spies M, Kowalczykowski SC (2003). "Homologous recombination by RecBCD and RecF pathways". In Higgins P. Bacterial Chromosomes ... When RecBCD resumes unwinding, it now cleaves the opposite strand (i.e., the 5' tail) and loads RecA protein onto the 3'-ended ... The Holliday junction can be resolved into linear DNA by the RuvABC complex or dissociated by the RecG protein. Each of these ...
*  Diguanylate cyclase
It was later noted that numerous bacterial genomes encoded multiple proteins with a GGDEF domain. Pseudomonas aeruginosa PAO1 ... Often, GGDEF domains with DGC activity are found in the same proteins as c-di-GMP-specific phosphodiesterase (PDE) EAL (Glu-Ala ... During the cell cycle of C. crescentus, proteins with GGDEF and EAL domains are separated towards the two distinct poles. The ... D'Argenio, D.A.; Miller, S.I. (2004). "Cyclic di-GMP as a bacterial second messenger". Microbiology. 150 (Pt 8): 2497-502. doi: ...
*  Pathogenicity island
They may be located on a bacterial chromosome or may be transferred within a plasmid or can be found in bacteriophage genomes. ... Regulation genes typically encoded on PAIs include AraC-like proteins and two-component response regulators. PAIs can be ... They can be transferred as a single unit to new bacterial cells, thus conferring virulence to formerly benign strains. PAIs, a ... Groisman E (1996). "Pathogenicity Islands: Bacterial Evolution in Quantum Leaps". Cell. 87: 791-794. doi:10.1016/s0092-8674(00) ...
*  Anthrax toxin
... the tripartite protein toxin, called anthrax toxin. Anthrax toxin is a mixture of three protein components: (i) protective ... The PA requirement observed in animal-model experiments demonstrates a common paradigm for bacterial toxins, called the A / B ... the synergistic effect of these three proteins leads to cellular death through a cascade of events that allow the proteins to ... Ratcheting up protein translocation with anthrax toxin. Prot Sci. 2012, 21(5):606-24. Abrami, L.; Liu, S.; Cosson, P.; Leppla, ...
*  DNA polymerase I
Pol I is part of the alpha/beta protein superfamily protein class, which consists of alpha and beta segments that are scattered ... The mutant strain developed bacterial colonies that continued to grow normally and that also lacked Pol I. This confirmed that ... throughout any given protein. E. coli DNA Pol I consists of four domains with two separate enzymatic activities. The fourth ...
*  Type VI secretion system
All characterized bacterial-targeting T6SS proteins act as toxins, either by killing or preventing the growth of target cells. ... T6SS-positive bacterial species prevent T6SS-mediated intoxication towards self and kin cells by producing immunity proteins ... It consists of the proteins TssE, TssF, TssG, and TssK. The baseplate and phage tail-like complex interact in the bacterial ... The T6SS is thought to resemble an inverted phage extending outward from the bacterial cell surface. It consists of 14 proteins ...
*  LdrD-RdlD toxin-antitoxin system
RdlD RNA (regulator detected in LDR-D) is a family of small non-coding RNAs which repress the protein LdrD in a type I toxin- ... Van Melderen L, Saavedra De Bast M (March 2009). "Bacterial toxin-antitoxin systems: more than selfish entities?". PLoS Genet. ... The LdrD protein causes growth inhibition, loss of cell viability, nucleoid condensation and alteration in purine metabolism ... Fozo EM, Hemm MR, Storz G (December 2008). "Small toxic proteins and the antisense RNAs that repress them". Microbiol. Mol. ...
*  Outer membrane porin D
... is a protein family containing bacterial outer membrane porins which are involved in transport of ... However many of these proteins are not peptidases and are classified as non-peptidase homologues as they either have been found ... Yoshihara E, Yoneyama H, Ono T, Nakae T (June 1998). "Identification of the catalytic triad of the protein D2 protease in ...
*  Bx1 benzoxazin1
The X-ray structure of BX1 protein has been resolved and compared with bacterial TSA (tryptophan synthase alpha subunit, Kulik ... 2005). Three homologs of the BX1 protein occur in maize. One is encoded by the gene tsa1, tryptophan synthase alpha1(Frey et al ... Molecular characterization reveals that the BX1 protein is a homologue to the alpha-subunit of tryptophan synthase. The ... "Anchoring 9,371 maize expressed sequence tagged unigenes to the bacterial artificial chromosome contig map by two-dimensional ...
*  Bacteriophage MS2
Bacterial lysis and release of newly formed virions occurs when sufficient lysis protein has accumulated. Lysis protein forms ... It encodes just four proteins: the maturation protein (A-protein), the lysis protein, the coat protein, and the replicase ... Finally, the lysis protein gene can only be initiated by ribosomes that have completed translation of the coat protein gene and ... It consists of one copy of the maturation protein and 180 copies of the coat protein (organized as 90 dimers) arranged into an ...
*  Fusidic acid
... acts as a bacterial protein synthesis inhibitor by preventing the turnover of elongation factor G (EF-G) from the ... Fusidic acid inhibits bacterial translation and does not kill the bacteria, and is therefore termed "bacteriostatic". Fusidic ... In vitro susceptibility studies of U.S. strains of several bacterial species such as S. aureus, including MRSA and coagulase ... Fusidic acid bound to proteins in the PDB. ...
*  Entamoeba histolytica
... which have similarity with bacterial restriction endonuclease. This similarity with bacterial protein indicates that ... The parasite has several enzymes such as pore forming proteins, lipases, and cysteine proteases, which are normally used to ... reannotation and analysis of the Entamoeba histolytica genome reveal new genomic features and protein content information. PLoS ... protein (in addition to reverse transcriptase and nucleotide-binding ORF1), ...
*  Ferric uptake regulator family
In molecular biology, the ferric uptake regulator family is a family of bacterial proteins involved in regulating metal ion ... Pohl E, Haller JC, Mijovilovich A, Meyer-Klaucke W, Garman E, Vasil ML (Feb 2003). "Architecture of a protein central to iron ... In the case of the ferric uptake regulator protein itself, its immediate downstream target is a noncoding RNA called RyhB. In ... Metal homeostasis can be a factor in bacterial virulence, an observation with a particularly long history in the case of iron. ...
*  EAL domain
In molecular biology, the EAL domain is a conserved protein domain. It is found in diverse bacterial signalling proteins. It is ...
*  Type three secretion system
Bacterial proteins that need to be secreted pass from the bacterial cytoplasm through the needle directly into the host ... The secreted effector proteins are secreted directly from the bacterial cell into the eukaryotic (host) cell, where they exert ... Pallen M. J.; Bailey C. M.; Beatson S. A. (2006). "Evolutionary links between Flih/Yscl-like proteins from bacterial type iii ... Since the beginning of the 1990s new T3SS proteins are being found in different bacterial species at a steady rate. ...
*  Ganglioside
... head groups also act as specific receptors for certain pituitary glycoprotein hormones and certain bacterial protein toxins ...
*  Fasciclin domain
Bacterial immunogenic protein MPT70 (1 FAS1 domain). The FAS1 domains of both human periostin and BIgH3 proteins were found to ... Proteins known to contain a FAS1 domain include: Fasciclin I (4 FAS1 domains). Human TGF-beta induced Ig-H3 (BIgH3) protein (4 ... FAS1 domains are present in many secreted and membrane-anchored proteins. These proteins are usually GPI anchored and consist ... Volvox major cell adhesion protein (2 FAS1 domains). Arabidopsis thaliana fasciclin-like arabinogalactan proteins (2 FAS1 ...
*  Poison
Some poisons are also toxins, which is any poison produced by animals, vegetables or bacterium, such as the bacterial proteins ... However, the same reactivity makes it also highly reactive towards proteins in human tissue and thus highly toxic. In fact, ... This treatment, however, only works with poisons composed of protein-molecules. In the majority of poisonings the mainstay of ...
*  Potassium transporter family
The bacterial proteins are of 423-558 residues, the Triticum aestivum protein is 533 residues, and the yeast proteins vary ... the Gram-negative and Gram-positive bacterial Ktr proteins, the yeast proteins and the plant proteins comprising four distinct ... reveals that the proteins cluster according to phylogeny of the source organism with the Gram-negative bacterial Trk proteins, ... The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and plants. The phylogenetic ...
*  MutS-1
Yeast MSH3, bacterial proteins involved in DNA mismatch repair, and the predicted protein product of the Rep-3 gene of mouse ... This entry represents the N-terminal domain of proteins in the MutS family of DNA mismatch repair proteins, as well as closely ... and together these proteins have been grouped into the MutS family. Although many of these proteins have similar activities to ... Human MSH has been implicated in non-polyposis colorectal carcinoma (HNPCC) and is a mismatch binding protein. Nag N, Rao BJ, ...
*  Mycobacterium
2009). "Secreted and Exported Proteins Important to Mycobacterium tuberculosis Pathogenesis". Bacterial Secreted Proteins: ... As with other bacterial pathogens, surface and secreted proteins of M. tuberculosis contribute significantly to the virulence ... Additionally, 14 proteins are found only in the species from the genera Mycobacterium and Nocardia, suggesting that these two ... For instance, the genome of M. vulneris encodes 6,653 proteins, which is larger than that of small eukaryotes such as yeast ( ...
*  Mycobacterium tuberculosis
2009). Bacterial Secreted Proteins: Secretory Mechanisms and Role in Pathogenesis. Caister Academic Press. ISBN 978-1-904455-42 ... These proteins have a conserved N-terminal motif, deletion of which impairs growth in macrophages and granulomas. Nine ... About 10% of the coding capacity is taken up by the PE/PPE gene families that encode acidic, glycine-rich proteins. ... Many secreted and exported proteins are known to be important in pathogenesis. Aerolysin is a virulence factor of the ...
*  Digestion
ISBN 978-0-674-03116-6. Wooldridge K (editor) (2009). Bacterial Secreted Proteins: Secretory Mechanisms and Role in ... It is a simple system, which consists of only three protein subunits: the ABC protein, membrane fusion protein (MFP), and outer ... It serves primarily as a site for acid hydrolysis of microbial and dietary protein, preparing these protein sources for further ... As protein enters the stomach, it binds to hydrogen ions, which raises the pH of the stomach. Inhibition of gastrin and gastric ...
*  Pseudomonas
Bacterial Secreted Proteins: Secretory Mechanisms and Role in Pathogenesis. Caister Academic Press. ISBN 978-1-904455-42-4. ... Like most bacterial genera, the pseudomonad last common ancestor lived hundreds of millions of years ago. They were initially ... Although not strictly a plant pathogen, P. tolaasii can be a major agricultural problem, as it can cause bacterial blotch of ... Young JM (1970). "Drippy gill: a bacterial disease of cultivated mushrooms caused by Pseudomonas agarici n. sp". NZ J Agric Res ...
*  Ada (protein)
Ada, also called as O6 alkyl guanine transferase I (O6 AGT I), is an enzyme induced by treatment of bacterial cells with ... Methylation of Ada protein converts it into a self transcriptional activator, inducing its own gene expression and the ... McCarthy TV, Lindahl T (1985). "Methyl phosphotriesters in alkylated DNA are repaired by the Ada regulatory protein of E. coli ...
*  Salmonella enterica
Hensel M (2009). "Secreted Proteins and Virulence in Salmonella enterica". Bacterial Secreted Proteins: Secretory Mechanisms ... Small non-protein coding RNAs (sRNA) are able to perform specific functions without being translated into proteins. 97 ... Secreted proteins are of major importance for the pathogenesis of infectious diseases caused by Salmonella enterica. A ... Secreted proteins are also involved in host cell invasion and intracellular proliferation, two hallmarks of Salmonella ...