"Comodulation of CXCR4 and CD26 in human lymphocytes". The Journal of Biological Chemistry. 276 (22): 19532-19539. doi:10.1074/ ...
Presence in pituitary, brain, adrenal medulla, and lymphocytes". J. Biol. Chem. 262 (18): 8532-6. doi:10.1016/S0021-9258(18) ...
Lymphocytes include the B-cell lymphocytes that are the antibody-producing cells of the body, and are thus the main agents of ... A larger number of lymphocytes in the lymph nodes, bone marrow, and skin means the body is increasing its humoral immune ... B-cell lymphocytes release antibodies into the bloodstream. These antibodies lower infection through three main pathways: ... There are many different kinds of antibody and their production is highly complex, involving several types of lymphocyte, but ...
1(3):186-92 Kabelitz D, Janssen O. (1997), Antigen-induced death of T-lymphocytes. Front Biosci. 2:d61-77 Green DR, Droin N, ... 2000), Activation-induced cell death in B lymphocytes. Cell Res. 10(3):179-92 Nagata S. (1997), Apoptosis by death factor. Cell ... AICD is a negative regulator of activated T lymphocytes that results from repeated stimulation of their T-cell receptors (TCR) ...
"Comodulation of CXCR4 and CD26 in human lymphocytes". The Journal of Biological Chemistry. 276 (22): 19532-9. doi:10.1074/jbc. ...
1996). "Phenotypic analysis of antigen-specific T lymphocytes". Science. 274 (5284): 94-96. Bibcode:1996Sci...274...94A. doi: ...
Cytotoxic T lymphocytes (CTLs) can recognize and destroy cancer cells. However, an inhibitory mechanism interrupts this ... T lymphocytes can recognize and destroy cancer cells. However, an inhibitory mechanism interrupts this destruction. Ipilimumab ... That signal binds to a receptor, cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), on the CTL and turns off the cytotoxic ... These antigens are recognized by dendritic cells that present the antigens to cytotoxic T lymphocytes (CTLs) in the lymph nodes ...
Morgan DA, Ruscetti FW, Gallo R (September 1976). "Selective in vitro growth of T lymphocytes from normal human bone marrows". ... Soon she was successful in growing T lymphocytes. Gallo, Morgan and Frank Ruscetti, another researcher in Gallo's lab, ... One such example was the report by Julius Gordon in 1965, which described blastogenic transformation of lymphocytes in ... Gordon J, Maclean LD (1965). "A Lymphocyte-stimulating Factor produced in vitro". Nature. 208 (5012): 795-796. Bibcode: ...
The CBMN assay has successfully been applied to normal human lymphocytes, mouse spleen lymphocytes, mouse fibroblasts and ... In order to do so, cytokinesis-block micronucleus assay (CBMN assay) with human lymphocytes is applied. This works in vitro. ... Ridler, MA; Smith, GA (1968). "The Response of Human Cultured Lymphocytes to Cytochalasin B". Journal of Cell Science. 3 (4): ... Smith, GF; Ridler, MA; Faunch, JA (16 December 1967). "Action of Cytochalasin B on Cultured Human Lymphocytes". Nature. 216 ( ...
In space, T-cells (a form of lymphocyte) are less able to reproduce properly, and the T-cells that do reproduce are less able ... In particular, it causes 'chromosomal aberrations' in lymphocytes. As these cells are central to the immune system, any damage ... High levels of radiation damage lymphocytes, cells heavily involved in maintaining the immune system; this damage contributes ...
After gaining a PhD in 1978 and producing a doctoral thesis titled 'Analysis of clones of cytotoxic lymphocytes' at the ... Ching, Lai-Ming (1978). Analysis of clones of cytotoxic lymphocytes (Doctoral thesis). ResearchSpace@Auckland, University of ...
Lin and Hamann's group show all human cytotoxic lymphocytes, including CD56dull NK cells and CD27-CD45RA+ effector-type CD8+ T ... October 2011). "Specific expression of GPR56 by human cytotoxic lymphocytes". Journal of Leukocyte Biology. 90 (4): 735-40. doi ...
In immunology, a memory B cell (MBC) is a type of B lymphocyte that forms part of the adaptive immune system. These cells ... Lymphocyte development and activation * Tumour immunology. 45: 126-131. doi:10.1016/j.coi.2017.03.003. PMID 28359033. Gatto D, ... Lymphocyte development and activation * Tumour immunology. 45: 97-102. doi:10.1016/j.coi.2017.03.006. PMID 28319733. Taylor JJ ... Lymphocyte development and activation * Tumour immunology. 45: 132-140. doi:10.1016/j.coi.2017.03.005. PMID 28363157. Allman D ...
... s are a sub-class of B cell lymphocytes that are involved in the humoral immune response. They are not part of the ... Alugupalli KR, Leong JM, Woodland RT, Muramatsu M, Honjo T, Gerstein RM (2004). "B1b lymphocytes confer T cell-independent long ... Bendelac A, Bonneville M, Kearney JF (2001). "Autoreactivity by design: innate B and T lymphocytes". Nature Reviews. Immunology ... Lymphocytes, Cells, Human cells, Immunology, Immune system). ...
T lymphocytes can detect a peptide displayed at 0.1-1% of the MHC molecules. In their development in the thymus, T lymphocytes ... T lymphocytes are selected for their TCR incapacity to recognize self antigens, yet T lymphocytes can react against the donor ... Antigen presentation: MHC molecules bind to both T cell receptor and CD4/CD8 co-receptors on T lymphocytes, and the antigen ... T lymphocytes of the recipient take the incompatible peptide-binding groove as nonself antigen.[clarification needed] ...
... knock-out mice show a defect in lymphocyte survival as KLF13 is a regulator of Bcl-xL expression. KLF13 has been shown to ... KLF13 was first described as the RANTES factor of late activated T lymphocytes (RFLAT)-1. It regulates the expression of the ... Song A, Nikolcheva T, Krensky AM (Oct 2000). "Transcriptional regulation of RANTES expression in T lymphocytes". Immunological ... a new zinc finger transcription factor that activates RANTES gene expression in T lymphocytes". Immunity. 10 (1): 93-103. doi: ...
... and/or autoreactive CD4+ T lymphocytes. Due to the variable bleeding phenotype of this disorder, the clinical picture ranges ...
Mature lymphocytes are also unable to proliferate indefinitely. Compounded, the reduction in number of naive lymphocytes and ... The reduced number of naive lymphocytes (T and B cells) is attributed to the fact that the telomeres in hematopoietic stem ... Other theories suggest that memory T lymphocytes play a role in the development of breakthrough infections. Breakthrough cases ... Because the telomeres in genes degenerate after each successive cell division, lymphocytes, including memory B cells are not ...
GPR56 has been shown to a marker for inflammatory NK cell subsets and to be expressed by cytotoxic lymphocytes. GPR126 is ... "Specific expression of GPR56 by human cytotoxic lymphocytes". Journal of Leukocyte Biology. 90 (4): 735-40. CiteSeerX 10.1. ...
This causal lentivirus can be found in monocytes, lymphocytes and macrophages of infected sheep in the presence of humoral and ... Infected differentiated monocytes, also known as macrophages, will continuously present VMV antigens inducing T-lymphocytes to ... visna virus does not infect T-lymphocytes. The relationship of visna and HIV as lentiviruses was first published in 1985 by ... "Mapping and characterization of visna/maedi virus cytotoxic T-lymphocyte epitopes". J. Gen. Virol. 89 (Pt 10): 2586-96. doi: ...
His major scientific contributions are in the area of lymphocyte homeostasis. In 2009 he published a textbook in immunology ... Freitas, AA; Rocha, B (2000). "Population biology of lymphocytes: the flight for survival". Annual Review of Immunology. 18: 83 ...
They may resemble lymphocytes, histiocytes, and plasma cells. Distribution of cells usually diffuse, they can form small groups ...
Histologically, the involved glands show lymphocyte-based lesions that are typical of EMZL with the infiltrating lymphocytes in ... They are lymphocytes of the B-cell line that originate and mature in secondary lymphoid follicles and then move to the marginal ... The lymphocytes have marker protein profiles (e.g. CD20 and Bcl-2 positive; CD5, cyclin D1 and CD10 negative) that are typical ... The lymphocytes in these lesions express B cell markers (e.g. CD19 and CD79a) typical of EMZL lesions. The best treatment ...
Davies ME, Barrett AJ (1984). "Immunolocalization of human cystatins in neutrophils and lymphocytes". Histochemistry. 80 (4): ...
Associated lymphoid organs are composed of lymphoid tissue, and are the sites either of lymphocyte production or of lymphocyte ... the spleen retains the ability to produce lymphocytes. The spleen stores red blood cells and lymphocytes. It can store enough ... Lymphocytes are initially generated in the bone marrow. The lymphoid organs also contain other types of cells such as stromal ... Lymphocytes enter the lymph nodes through specialised high endothelial venules found in the paracortex. A lymph follicle is a ...
Microscopic examination will show infiltration of lymphocytes and plasma cells. The lymphocytes are predominately T-lymphocytes ... Thyroid autoantibodies appear mostly with the presence of lymphocytes in the targeted organ. Lymphocytes produce antibodies ... It is located on chromosome 1p13 and expressed in lymphocytes. It acts as a negative regulator of T-cell activation. Mutation ... It is also characterized by invasion of the thyroid tissue by leukocytes, mainly T-lymphocytes. A rare but serious complication ...
Lymphocytes are a major target cell for DHOV. DHOV infection in mice resembles experimental influenza infection in mice and ...
1992). "T lymphocyte expression of complement receptor 2 (CR2/CD21): a role in adhesive cell-cell interactions and ... 1988). "Structure of the human B lymphocyte receptor for C3d and the Epstein-Barr virus and relatedness to other members of the ... 1986). "Identification of a partial cDNA clone for the C3d/Epstein-Barr virus receptor of human B lymphocytes: homology with ... 1993). "Functional dissection of the CD21/CD19/TAPA-1/Leu-13 complex of B lymphocytes". J. Exp. Med. 178 (4): 1407-17. doi: ...
... human lymphocytes. I. Two distinct phenotypes of human NK cells with different cytotoxic capability". Journal of Immunology. ...
Presence in pituitary, brain, adrenal medulla, and lymphocytes". J. Biol. Chem. 262 (18): 8532-6. doi:10.1016/S0021-9258(18) ...