The compound is also of interest for the synthesis of dendrimers, a process that exploits the tendency of aziridines to undergo ... It is a secondary amine and the smallest chiral aziridine (ring containing C2N). It is a flammable colorless liquid. Its ... "Aziridines". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a03_239.pub2. Global ... Aziridines, All stub articles, Heterocyclic compound stubs). ...

It is used industrially for the synthesis of aziridine itself. The original Wenker synthesis of aziridine itself takes place in ... The Wenker synthesis is an organic reaction converting a beta amino alcohol to an aziridine with the help of sulfuric acid. ... This salt is then reacted with sodium hydroxide in the second step forming aziridine. The base abstracts an amine proton ... Use dmy dates from May 2013, Ring forming reactions, Aziridines, Nitrogen heterocycle forming reactions, Heterocycle forming ...

Branched PEI can be synthesized by the ring opening polymerization of aziridine. Depending on the reaction conditions different ... Steuerle, Ulrich; Feuerhake, Robert (2006). "Aziridines". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. ...

Aziridines, Oximes). ...

2007). Aziridines and Epoxides in Organic Synthesis. p. 120. ISBN 978-3-527-31213-9. The quinazoline is prepared from the ... With alkenes, nitrenes react to form aziridines, very often with nitrenoid precursors such as nosyl- or tosyl-substituted [N-( ... Watson, Iain D. G.; Yu, Lily; Yudi, Andrei K. (2006). "Advances in Nitrogen Transfer Reactions Involving Aziridines". Acc. Chem ... result in the same trans-aziridine product, suggesting a two-step reaction mechanism. The energy difference between triplet and ...

Aziridines include thiotepa, mytomycin and diaziquone (AZQ). Cisplatin and derivatives include cisplatin, carboplatin and ... The subtypes of alkylating agents are the nitrogen mustards, nitrosoureas, tetrazines, aziridines, cisplatins and derivatives, ...

Aziridine-2,3-dione has an infrared absorption band at 1954 cm−1. The term "oximide" has also been used for oximes. Derivatives ... Its core is a three member heterocycle, aziridine. In 1886 Ost and Mente claimed to produce oximide by the reaction of oxamic ... Derivatives made this way are methyl, isopropyl and phenylethyl-aziridine-2,3-dione. These compounds are unstable at higher ... Aoyama, Hiromu; Sakamoto, Masami; Omote, Yoshimori (September 1980). "Aziridine-2,3-diones". Journal of the American Chemical ...

Note that with aziridines, ring opening can result in a different 1,3-dipole, in which a C-N bond (rather than the C-C bond) ... Cardoso, Ana L.; Pinho e Melo, Teresa M. V. D. (2012). "Aziridines in Formal [3+2]Cycloadditions: Synthesis of Five-Membered ... This is generally done by ring opening of an aziridine, and subsequent trapping by a dipolarophile before the stereochemistry ... Azomethine ylides can be generated from ring opening of aziridines. In accordance with the Woodward-Hoffmann rules, the thermal ...

... amino alcohols to the corresponding aziridines with diethoxytriphenylphosphorane". The Journal of Organic Chemistry. 51 (1): 95 ...

... ketononestrol aziridine) and antiestrogen (tamoxifen aziridine) in the human estrogen receptor". The Journal of Biological ... "Tamoxifen aziridines: effective inactivators of the estrogen receptor". Endocrinology. 109 (4): 1298-1300. doi:10.1210/endo-109 ...

"Recent Advances in the Stereoselective Synthesis of Aziridines". Chemical Reviews. 114 (16): 7881-7929. doi:10.1021/cr400553c. ...

Aziridine Reiss, G.J. (2011). "KUWQIF: Mitomycin C Dihydrate, also known as (6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8 ... Aziridines, Breakthrough therapy, Cancer treatments, Carbamates, Chemotherapy, Enones, Heterocyclic compounds with 4 rings, ...

"Directed Nickel-Catalyzed Negishi Cross Coupling of Alkyl Aziridines". Journal of the American Chemical Society. 135 (36): ...

Polymeric and oligomeric aziridines are one of the moieties used to crosslink waterborne resins. They usually react with the ... Bückmann, A. J. P.; Chen, Q.; Overbeek, G. C.; Stals, P. J. M.; van der Zwaag, D. (2022-09-01). "Polymeric aziridines as benign ...

Aziridine occurs by the cyclization of chloroethylamine; piperazines are formed by cyclization of a two-ethylene unit compound ...

Polyethylenimine is a polymer derived from aziridine. Synthetic polyamines Tris(2-aminoethyl)amine Cyclen 1,4,7- ...

Cyclopropenes, aziridines and cyclobutanes may be formed in a similar manner. Carbon acids which can be deprotonated by sodium ...

It can also cyclize 2-aminoalcohols to aziridines and to convert α,β-unsaturated carboxylic acids to α,β-unsaturated bromides. ... H. Suzuki; H. Tani (1984). "A mild cyclization of 2-aminoalcohols to aziridines using diphosphorus tetraiodide". Chemistry ...

... (BEI) is a preparation of aziridine. It can be produced by heating bromoethylamine hydrobromide or 2- ... v t e (Aziridines, Virucides, All stub articles, Organic chemistry stubs). ...

Additional Methods RajanBabu has evaluated asymmetric aziridine openings with high enantioselectivity using yttrium- and ... "Bimetallic catalysis in the highly enantioselective ring-opening reactions of aziridines". Chem. Sci. 5 (3): 1102-1117. doi: ...

2-amino alcohols and ethers from aziridines and organolithiums". Chem. Commun. Royal Society of Chemistry (RSC) (19): 2234-2235 ...

8, p. 434 Thibodeaux C. J. (2012). "Enzymatic Chemistry of Cyclopropane, Epoxide, and Aziridine Biosynthesis". Chem. Rev. 112 ( ...

It is made from aziridine and mesoporous silica. "Can we make tailpipes that capture CO2?". HowStuffWorks. 2008-05-27. ...

Diastereopure azomethine ylides are generated by electrocyclic ring opening of aziridines, and then rapidly trapped with strong ... Huisgen, Rolf; Scheer, Wolfgang; Huber, Helmut (1967). "Stereospecific Conversion of cis-trans Isomeric Aziridines to Open- ...

It is manufactured by heating aziridine with thiophosphoryl chloride.[citation needed] Thiotepa is indicated for use in ... Aziridines, Cancer treatments, IARC Group 1 carcinogens, Organophosphoric amides, Orphan drugs, Thiophosphoryl compounds). ...

Alternatively aziridine intermediate 9 directly forms the end=product. The formation of the nitrene intermediate 10 is ruled ...

"Direct Stereospecific Synthesis of Unprotected N-H and N-Me Aziridines from Olefins". Science. 343 (6166): 61-65. Bibcode: ...

... is the ionic form of the class of molecules known as aziridines. Aziridines can be used to insert nitrogen atoms ... Thus, aziridinium ions render nonactivated aziridines reactive, making them feasible to use in chemical synthesis. Although ... "Origin of the reactivity differences of substituted aziridines: CN vs CC bond breakages". The Journal of Organic Chemistry. 74 ... "Reactivity and regioselectivity in the ring opening of 2-substituted non-activated aziridines: A density functional theory ...

9) The aza-Payne rearrangement may be effected in either the "forward" (epoxide to aziridine) or "reverse" (aziridine to ... Electron-poor aziridines undergo the reverse rearrangement in the presence of hydride base, while the corresponding epoxy ... Aza- and thia-Payne rearrangements of aziridines and thiiraniums, respectively, are also known. Under basic, protic conditions ...

A methylene transfer reaction of an imine by an unstabilised sulphonium ylide can give an aziridine system. Imine react with ... Thus, ethylenimine is the three-membered ring species aziridine C2H4NH. The relationship of imines to amines having double and ... Primary aldimine, E-isomer Secondary aldimine, E-isomer Primary ketimine Secondary ketimine Aziridine and its derivatives are ...