Zhou J, Peng X, Mei S (2019). "Autophagy in Ovarian Follicular Development and Atresia". International Journal of Biological ...

Autophagy is the main mechanism at the molecular level, but evidence has been found for other mechanisms, including ... It also was found to reduce the amount of aging in yeast, flies, worms, and human immune cells by inducing autophagy. ... November 2009). "Induction of autophagy by spermidine promotes longevity". Nat. Cell Biol. 11 (11): 1305-14. doi:10.1038/ ... "GAS5/miR-21 Axis as a Potential Target to Rescue ZCL-082-Induced Autophagy of Female Germline Stem Cells In Vitro". Molecular ...

Behrends C, Sowa ME, Gygi SP, Harper JW (July 2010). "Network organization of the human autophagy system". Nature. 466 (7302): ...

Behrends C, Sowa ME, Gygi SP, Harper JW (2010). "Network organization of the human autophagy system". Nature. 466 (7302): 68-76 ...

Edinger AL, Thompson CB (December 2004). "Death by design: apoptosis, necrosis and autophagy". Current Opinion in Cell Biology ...

During selective autophagy, cargo is specifically targeted for degradation, and distinct cargo receptors have been described ... Ubiquitination plays a central role for marking proteins to be degraded either via the autophagy pathway or via the proteasome ... CEF scientists showed that GABARAP proteins are not only involved in autophagy but also in the ubiquitin-dependent degradation ... They further discovered that reticulon-type proteins act as ER-specific autophagy receptors and simulated their effect on the ...

... she published evidence of altered chaperone-mediated autophagy in Parkinson's disease. Similar findings of disrupted autophagy ... She is best known for her research work on autophagy, the process by which cells recycle waste products, and its changes in ... Cuervo is also one of the founding members of the Women in Autophagy (WIA) network dedicate to promote careers of young ... She continue primarily focusing on chaperone-mediated autophagy and its role in aging and human disease. Her research lab ...

Rubicon is a negative regulator of autophagy. Other key interactions include RAC1 (By similarity), NTRK1/TRKA (By similarity), ... "Structural basis for autophagy inhibition by the human Rubicon-Rab7 complex". Proceedings of the National Academy of Sciences ...

Heaton, N.S.; Randall, G (2010). "Dengue virus-induced autophagy regulates lipid metabolism". Cell Host Microbe. 8 (5): 422-32 ...

Nixon RA (August 2013). "The role of autophagy in neurodegenerative disease". Nature Medicine. 19 (8): 983-97. doi:10.1038/nm. ...

The balance of autophagy within the cell and the crosstalk between autophagy and apoptosis mediated by ROS is crucial for a ... Therefore, autophagy can also regulate the cell's health in times of oxidative stress. Autophagy can be induced by ROS levels ... but a newer line of study has connected ROS levels and autophagy. ROS can also induce cell death through autophagy, which is a ... induced autophagy for cancer therapy". Autophagy. 6 (7): 835-837. doi:10.4161/auto.6.7.13335. PMID 20818163. Shrivastava A, ...

December 2018). "The ULK1-FBXW5-SEC23B nexus controls autophagy". eLife. 7. doi:10.7554/eLife.42253. PMC 6351106. PMID 30596474 ...

November 2009). "Induction of autophagy by spermidine promotes longevity". Nature Cell Biology. 11 (11): 1305-1314. doi:10.1038 ...

Under energy stress conditions, PGK1 phosphorylates Beclin1 to regulate autophagy of cancer cells. In addition, he demonstrated ... induces gene expression for lysosomal biogenesis and autophagy 1999 - The Pioneer Fund Fellowship, The Salk Institute 2000 - ... "Phosphoglycerate Kinase 1 Phosphorylates Beclin1 to Induce Autophagy". Molecular Cell. 65 (5): 917-931.e6. doi:10.1016/j.molcel ... "Phosphoglycerate Kinase 1 Phosphorylates Beclin1 to Induce Autophagy". Molecular Cell. 65 (5): 917-931.e6. doi:10.1016/j.molcel ...

Wileman T (May 2006). "Aggresomes and autophagy generate sites for virus replication". Science. 312 (5775): 875-8. Bibcode: ...

Both ambroxol and its parent drug bromhexine have been shown to induce autophagy in several cell types, and ambroxol was shown ... Choi SW, Gu Y, Peters RS, Salgame P, Ellner JJ, Timmins GS, Deretic V (September 2018). "Ambroxol Induces Autophagy and ... October 2015). "Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational ...

... in the process of cell-eating called autophagy) by the lysosomes. It then moves towards the nucleus, specifically at the ... "Active escape of Orientia tsutsugamushi from cellular autophagy". Infection and Immunity. 81 (2): 552-559. doi:10.1128/IAI. ...

"Regulation of endoplasmic reticulum turnover by selective autophagy". Nature. 522 (7556): 354-358. Bibcode:2015Natur.522..354K ...

Qian M, Tan HM, Yu N, Wang T, Zhang Q (April 2018). "Inactivated Sendai Virus Induces ROS-dependent Apoptosis and Autophagy in ... Lee HK, Lund JM, Ramanathan B, Mizushima N, Iwasaki A (March 2007). "Autophagy-dependent viral recognition by plasmacytoid ... The functional TDRD7 protein inhibits the replication of SeV and other paramyxoviruses, suppressing autophagy, which is ... January 2018). "A new mechanism of interferon's antiviral action: Induction of autophagy, essential for paramyxovirus ...

Kumar, S.; Guru, S K; Pathania, A S; Kumar, A.; Bhushan, S.; Malik, F. (1 October 2013). "Autophagy triggered by magnolol ... Pathania, Anup S.; Makhdoomi, Ubaid S.; Malik, Fayaz A. (2017). "Genetic and Epigenetic Regulation of Autophagy in Cancer". ... "The anti-angiogenic and cytotoxic effects of the boswellic acid analog BA145 are potentiated by autophagy inhibitors". ... "Interplay between cell cycle and autophagy induced by boswellic acid analog". Scientific Reports. 6 (1): 33146. Bibcode: ...

Moreover, mTORC2 activity has been implicated in the regulation of autophagy(macroautophagy and chaperone-mediated autophagy). ... Ballesteros-Álvarez J, Andersen JK (August 2021). "mTORC2: The other mTOR in autophagy regulation". Aging Cell. 20 (8): e13431 ... Yang Z, Klionsky DJ (April 2010). "Mammalian autophagy: core molecular machinery and signaling regulation". Current Opinion in ... Maiese K (June 2020). "New Insights for nicotinamide: Metabolic disease, autophagy, and mTOR". Frontiers in Bioscience. 25 (11 ...

Singh SB, Davis AS, Taylor GA, Deretic V (September 2006). "Human IRGM induces autophagy to eliminate intracellular ...

September 2009). "Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium ... January 2009). "Autophagy and pattern recognition receptors in innate immunity". Immunological Reviews. 227 (1): 189-202. doi: ... The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to ... December 2010). "Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria". Nature Cell ...

Choi SW, Gu Y, Peters RS, Salgame P, Ellner JJ, Timmins GS, Deretic V (September 2018). "Ambroxol Induces Autophagy and ... through host directed effects in autophagy and pharmacokinetics). Rifampicin inhibits bacterial DNA-dependent RNA synthesis by ...

Cancer Res., (2009) 69, p. 358-68 Mazure NM, et al., « Hypoxia-induced autophagy: cell death or cell survival? », Curr Opin ... autophagy, nutritional stress and aberrant tumor metabolism. The team is pursuing, at a fundamental, translational and pre- ...

... lymphocyte survival and autophagy". Autophagy. 5 (2): 232-4. doi:10.4161/auto.5.2.7445. PMC 2749220. PMID 19066452. Singh SB, ... Human IRGM like its mouse counterpart, has been shown to play a role in autophagy, the mechanism of which is not fully ... Under autophagy inducing conditions, IRGM also increases ROS (Reactive Oxygen Species) production. High levels of IRGMd ... The presence of LC3-II serves as a marker for autophagy and can be detected by immunofluorescence or immunoblotting. IRGM helps ...

"Insulin secretory granules control autophagy in pancreatic cells". Science. 347 (6224): 878-882. doi:10.1126/science.aaa2628. ...

It has been involved in the regulation of autophagy, of endothelial cell and inhibits angiogenesis. This process is mediated by ... July 2013). "Decorin causes autophagy in endothelial cells via Peg3". Proceedings of the National Academy of Sciences of the ...

Although normal autophagy helps maintain muscle, excessive autophagy causes loss of muscle mass.) It has been found that the ... Zhou H, Pu S, Zhou H, Guo Y (2021). "Klotho as Potential Autophagy Regulator and Therapeutic Target". Frontiers in Pharmacology ... An abnormal form of autophagy associated with reduced expression of klotho is linked to the pathogenesis of chronic obstructive ...

Known autophagy receptors are characterized by short linear sequence motifs (autophagy receptor motifs, or ARMs) responsible ... Autophagy Receptor Motif Plotter assists in the identification of novel ARM-CPs. Users input a given an amino acid sequence ... The autophagy pathway is mediated by selective receptors. They recognize and sort diverse cargo substrates (e.g., proteins, ... Antibodies Autophagy database Neurodegenerative disorders Stem cell marker SUMO protein WuXi PharmaTech Acquires Abgent, a ...