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*  Autoantibody
The role of autoantibodies in normal immune function is also a subject of scientific research. The causes of autoantibody ... Those who have more than one autoimmune disorder may have several detectable autoantibodies. Whether a particular autoantibody ... the autoantibodies may develop. Systemic autoantibody tests are used to: Help diagnose systemic autoimmune disorders. Help ... leading to production of pathological autoantibodies. These autoantibodies attack the body's own healthy cells, tissues, and/or ...
*  Systemic lupus erythematosus
Anti-nRNP autoantibodies to nRNP A and nRNP C initially targeted restricted, proline-rich motifs. Antibody binding subsequently ... The mechanism involves an immune response by autoantibodies against a person's own tissues. These are most commonly anti- ... The similarity and cross-reactivity between the initial targets of nRNP and Sm autoantibodies identifies a likely commonality ... Adam Reich, Katarzyna Marcinow, and Rafal Bialynicki-Birula Buyon JP, Clancy RM (December 2003). "Maternal autoantibodies and ...
*  LRBA deficiency
Because the predominant features of the disease include autoantibody-mediated disease (AIHA, ITP), Treg defects (resembling ... the disease has been termed LATAIE for LRBA deficiency with autoantibodies, Treg defects, autoimmune infiltration, and ...
*  Autoimmune hemolytic anemia
AIHA cannot be attributed to any single autoantibody. To determine the autoantibody or autoantibodies present in a patient, the ... Cold autoantibodies act best at temperatures of 0-4 °C. Patients with cold-type AIHA, therefore, have higher disease activity ... Patients may present with one or both types of autoantibodies; if both are present, the disease is termed "mixed-type" AIHA. ... These classifications are based on the characteristics of the autoantibodies involved in the pathogenesis of the disease. Each ...
*  Bullous pemphigoid
The bullae are formed by an immune reaction, initiated by the formation of IgG autoantibodies targeting Dystonin, also called ...
*  Warm antibody autoimmune hemolytic anemia
The autoantibody model proposes that, through a mechanism not yet understood, certain drugs will cause antibodies to be made ... There are two models for this: the hapten model and the autoantibody model. The hapten model proposes that certain drugs, ...
*  Anti-thyroid autoantibodies
Antithyroid autoantibodies (or simply anti-thyroid antibodies) are autoantibodies targeted against one or more components on ... Anti-Na+/I− symporter antibodies are a more recent discovery of possible thyroid autoantibodies and their role in thyroid ... Saravanan P, Dayan CM (June 2001). "Thyroid autoantibodies". Endocrinol. Metab. Clin. North Am. 30: 315-37, viii. doi:10.1016/ ... Anti-TPO antibodies are the most common anti-thyroid autoantibody, present in approximately 90% of Hashimoto's thyroiditis, 75 ...
*  Adrenergic receptor autoantibodies
... autoantibodies to these receptors have been tied to many different heart diseases. Autoantibodies to beta1-adrenergic receptors ... Adrenergic receptor autoantibodies The adrenergic receptors (or adrenoreceptors) are a class of cell membrane-bound protein ... Adrenergic autoantibodies have been linked to Buerger's disease (thromboangiitis obliterans). Buerger's disease is a rare ... "Beta1 autoantibodies trigger conformational changes in the receptor, attenuate receptor internalization. The combination of ...
*  Anti-SSA/Ro autoantibodies
... or the combination anti-SSA/Ro or anti Ro/SSA autoantibodies) are anti-nuclear autoantibodies that are associated with many ... Anti-SSA autoantibodies (Anti-Sjögren's-syndrome-related antigen A, also called anti-Ro, ... 2007). "Clinical significance of autoantibodies recognizing Sjögren's syndrome A (SSA), SSB, calpastatin and alpha-fodrin in ...
*  P-ANCA
Yehuda Shoenfeld; M. Eric Gershwin; Pier-Luigi Meroni (2007). Autoantibodies. Elsevier. pp. 98-. ISBN 978-0-444-52763-9. ...
*  Yehuda Shoenfeld
Natural Autoantibodies : Their Physiological Role and Regulatory Significance cover Natural Autoantibodies : Their ... Autoantibodies. by Yehuda Shoenfeld (Editor), J.B. Peter (Editor). 1996. The Antiphospholipid Syndrome. by Ricard Cervera ( ...
*  RAS-associated autoimmune leukoproliferative disorder
Autoantibodies are also common. Investigators at the National Institute of Allergy and Infectious Diseases at the US National ...
*  Anti-nuclear antibody
This is the highest dilution of the serum at which autoantibodies are still detectable. Positive autoantibody titres at a ... Category:Chemical pathology Autoantibodies Haserick, John R., Lena A. Lewis, and Donald W. Bortz. "Blood factor in acute ... Autoantibody screening is useful in the diagnosis of autoimmune disorders and monitoring levels helps to predict the ... In case no defined autoantibody can be detected (e.g. anti-ENA antibodies), the testing of anti-DFS70 antibodies is recommended ...
*  CD38
Mallone R, Perin PC (2006). "Anti-CD38 autoantibodies in type? diabetes". Diabetes Metab. Res. Rev. 22 (4): 284-94. doi:10.1002 ...
*  CD74
See Milatuzumab#CD74 Autoantibodies against CD74 have been identified as a promissing biomarkers in the early diagnosis of the ... "Autoantibodies against CD74 in spondyloarthritis". Annals of the Rheumatic Diseases. 73 (6): 1211-14. doi:10.1136/annrheumdis- ...
*  Reference ranges for blood tests
Autoantibodies are usually absent or very low, so instead of being given in standard reference ranges, the values usually ... Autoantibodies associated with rheumatic diseases > Reference ranges Retrieved on April 29, 2010 Rajkumar SV, Kyle RA, Therneau ...
*  Anti-citrullinated protein antibody
The presence of autoantibodies against citrullinated proteins in rheumatoid arthritis patients was first described in the mid- ... chronolab.com > Autoantibodies associated with rheumatic diseases > Reference ranges Retrieved on 29 April 2010. ... Subsequent studies demonstrated that autoantibodies from RA patients react with a series of different citrullinated antigens, ... Anti-citrullinated protein antibodies (ACPAs) are autoantibodies (antibodies to an individual's own proteins) that are directed ...
*  Anti-histone antibodies
Muller, Sylviane (2014). Chapter 23 - Histone Autoantibodies, In Autoantibodies (Third ed.). San Diego, CA. p. 195. ISBN ... Anti-histone antibodies are autoantibodies that are a subset of the anti-nuclear antibody family. They are found in 50%-70% of ... chronolab.com > Autoantibodies associated with rheumatic diseases > Reference ranges Retrieved on April 29, 2010. ...
*  Anti-dsDNA antibodies
This effect can also occur after an infection causes the production of autoantibodies to other structures within the nucleus. ... Subsequently, in 1957, antibodies to dsDNA were the first autoantibodies to be identified in patients with SLE. Although the ... Hueber W, Utz PJ, Steinman L, Robinson WH (2002). "Autoantibody profiling for the study and treatment of autoimmune disease". ... Automated analysis of the well fluorescence allows for rapid detection of autoantibodies. Microarrays are a newly emerging ...
*  Myelin oligodendrocyte glycoprotein
Reindl M, Di Pauli F, Rostásy K, Berger T (August 2013). "The spectrum of MOG autoantibody-associated demyelinating diseases". ... "A single Ig-domain is exposed to the extracellular space" and consequently allows autoantibodies easy access. and therefore ... 2015). "Spectrum of MOG Autoantibody-Associated Inflammatory Diseases in Pediatric Patients". Neurology. 84 (14): Supplement I4 ... and it has been found to be associated with anti-MOG autoantibodies The anti-mog spectrum in children is equally variated: Out ...
*  Anti-nRNP
They are autoantibodies against some ribonucleoproteins. One form of Anti-nRNP is antibodies towards snRNP70 (then called anti- ... "Human anti-nuclear ribonucleoprotein antigen autoimmune sera contain a novel subset of autoantibodies that stabilizes the ...
*  Pemphigus
Desmoglein 1, the protein that is destroyed by the autoantibody, is found in only the top dry layer of the skin. PF is ... When autoantibodies attack desmogleins, the cells become separated from each other and the epidermis becomes "unglued", a ... The name is derived from the Greek root "pemphix" meaning "pustule". In pemphigus, autoantibodies form against desmoglein. ... autoantibodies reacting against epithelial adhesion molecules. Pemphigus is further divided in two major subtypes: pemphigus ...
*  Paolo Casali
They also blunt autoantibody responses in lupus-prone mice, thereby alleviating lupus immunopathology and outline an important ... Structure-function analysis of a lupus anti-DNA autoantibody: central role of the heavy chain CDR3 Arg in binding of dsDNA and ... Small molecule inhibitor of Rab7 impairs B cell class-class switching and plasma cell survival to dampen the autoantibody ... Nature and functions of autoantibodies. Nature Rev. Rheum. 4:491-498. PMID 18756274; PMCID: PMC2703183. Xu, Z., S. Pal, H. Zan ...
*  Myenteric plexus
"Autoantibodies to Auerbach's plexus in achalasia". Cellular and molecular biology (Noisy-le-Grand, France). 41 (8): 1033-8. ...
*  Lupus nephritis
Autoantibodies direct themselves against nuclear elements. The characteristics of nephritogenic autoantibodies ( lupus ... autoantibodies of certain isotypes activate complement. The diagnosis of lupus nephritis depends on blood tests, urinalysis, X- ... nephritis) are: antigen specificity directed at nucleosome, high affinity autoantibodies form intravascular immune complexes, ...