Cresto N, Pillet LE, Billuart P, Rouach N (August 2019). "Do Astrocytes Play a Role in Intellectual Disabilities?". Trends in ... MeCP2 deficiency leads to less Kir4.1 channels present on astrocytes in the brain. Since there are fewer channels allowing ...
There, she carried out research on the role of astrocytes and in synapse formation by triggering neurons to produce a protein ... Microglia may contribute to disease both by phagocytosing synaptic material and activating neurotoxic astrocytes. Her research ... "Neurotoxic reactive astrocytes are induced by activated microglia". Nature. 541 (7638): 481-487. Bibcode:2017Natur.541..481L. ...
PEA in this model also reduced the activation of microglia and astrocytes. Its activity as an inhibitor of inflammation ... Nakagawa T, Kaneko S (2010). "Spinal astrocytes as therapeutic targets for pathological pain". Journal of Pharmacological ... July 2011). "Palmitoylethanolamide stimulation induces allopregnanolone synthesis in C6 Cells and primary astrocytes: ...
... remove ERα from astrocytes. It was found that the mice with ERα knocked out in astrocytes experienced an increase in clinical ... In a 2011 research article, Voskuhl published data revealing that the estrogen receptor α (ERα) on astrocytes, not neurons, was ... "Neuroprotection mediated through estrogen receptor-α in astrocytes". Proceedings of the National Academy of Sciences of the ...
Mohammed BB (1 October 2010). "The Blood Brain Barrier and Astrocytes type 1". Archived from the original on 8 April 2023. ...
Zidarič, Tanja; Gradišnik, Lidija; Velnar, Tomaž (2022-04-01). "Astrocytes and human artificial blood-brain barrier models". ...
Some glial cells (astrocytes) can even propagate intercellular calcium waves over long distances in response to stimulation, ... Wound scars in the brain largely contain astrocytes. The extracellular matrix also provides support on the molecular level for ...
Walter L, Franklin A, Witting A, Moller T, Stella N (June 2002). "Astrocytes in culture produce anandamide and other ...
... astrocytes, and neuroblastoma cells; liver hepatocytes; various types of epithelial cells; and various types of multicellular ...
Myelinoid (Myelin organoid) Blood-brain barrier (BBB) organoid Self-assembled cell aggregates consisting of BMECs, astrocytes, ... "Astrocytes and human artificial blood-brain barrier models". Bosnian Journal of Basic Medical Sciences. 22 (5): 651-672. doi: ...
Wang Y, Cui J, Sun X, Zhang Y (April 2011). "Tunneling-nanotube development in astrocytes depends on p53 activation". Cell ... Blocking CD38, which had been implicated in the release of mitochondria by astrocytes, also significantly decreased TNT ... July 2016). "Transfer of mitochondria from astrocytes to neurons after stroke". Nature. 535 (7613): 551-555. Bibcode:2016Natur. ... December 2012). "Tunneling-nanotube direction determination in neurons and astrocytes". Cell Death & Disease. 3 (12): e438. doi ...
YKL-40 is a migration factor for primary astrocytes and its expression is controlled by NFI-X3, STAT3, and AP-1. CHI3l1 is ... This leads to increased Chi3l1 expression in astrocytes. There is evidence that YKL-40 levels are elevated in Alzheimer's ... "A complex of nuclear factor I-X3 and STAT3 regulates astrocyte and glioma migration through the secreted glycoprotein YKL-40". ...
"Entrez Gene: PEA15 phosphoprotein enriched in astrocytes 15". Böck BC, Tagscherer KE, Fassl A, Krämer A, Oehme I, Zentgraf HW, ... particularly in astrocytes. PEA-15 promotes autophagy in glioma cells in a JNK-dependent manner. PEA15 has been shown to ... a major substrate for protein kinase C in astrocytes". J. Biol. Chem. 268 (8): 5911-20. doi:10.1016/S0021-9258(18)53407-4. PMID ... "Knock-out of the neural death effector domain protein PEA-15 demonstrates that its expression protects astrocytes from TNFalpha ...
When AHPCs were grown on micropatterned substrates with astrocytes, outgrowth was influenced by the astrocytes that had aligned ... Growing axons are guided by cues created by astrocytes; thus, astrocytes can regulate neurite pathfinding and subsequently, ... Astrocytes are glial cells that are abundant in the central nervous system. They are crucial for the metabolic and trophic ... Astrocytes are specific to the central nervous system; they provide nutrients, physical support, and insulation for neurons. ...
He also found that large populations of astrocytes negative to classical marker GFAP but positive to glutamine synthetase or ... Subsequently, he identified a unique expression of highly ATP-sensitive P2X1/5 receptors in cortical astrocytes and ... First, in collaboration with Rodriguez, he discovered prominent inhibition of neurogenesis (linked to the radial astrocytes- ... After moving to Manchester, Verkhratsky focused on astroglia and characterised various aspects of astrocyte membrane physiology ...
Astrocytes also exchange information with the synaptic neurons, responding to synaptic activity and, in turn, regulating ... Perea, G.; Navarrete, M.; Araque, A. (August 2009). "Tripartite synapses: astrocytes process and control synaptic information ...
The ependymal cells and astrocytes form glial tubes used by migrating neuroblasts. The astrocytes in the tubes provide support ... The astrocytes are the primary precursors for rapid cell amplification. The neuroblasts form tight chains and migrate towards ... Reynolds, B.; Weiss, S (1992). "Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous ... NSCs have an important role during development producing the enormous diversity of neurons, astrocytes and oligodendrocytes in ...
Reactive astrocytes are related to the normal function of astrocytes. Astrocytes are involved in the complex regulation of CNS ... Astrocytes interact extensively with microglia and play a key role in CNS inflammation. Reactive astrocytes can then lead to ... Loss or disturbance of functions normally performed by astrocytes or reactive astrocytes during the process of reactive ... Mature astrocytes can re-enter the cell cycle and proliferate during scar formation. Some proliferating reactive astrocytes can ...
Glutamate-mediated astrocyte-neuron signalling. 369:6483. 744-747. Nature. 1994. Hui Hu, Yingchun Ni, Vedrana Montana, Robert C ... Glutamate‐dependent astrocyte modulation of synaptic transmission between cultured hippocampal neurons. 10:6. 2129:2142. ... His interests are in ion channels, astrocyte-neuron glutamate-mediated signaling, synaptic function and Glial biology. His ...
2005). "Increased peptidylarginine deiminase type II in hypoxic astrocytes". Biochem. Biophys. Res. Commun. 325 (4): 1324-9. ...
... which is exported to astrocytes. In the astrocytes, this process is then reversed, and lactate is transported in the other ... Astrocytes could dispose of transported glutamate in two ways. They could export it to blood capillaries, which abut the ... Astrocytes readily convert glutamate to glutamine via the glutamine synthetase pathway and released into the extracellular ... When one molecule of glutamate or GABA is converted to glutamine in the astrocytes, one molecule of ammonia is absorbed. Also, ...
Teismann P, Schulz JB (October 2004). "Cellular pathology of Parkinson's disease: astrocytes, microglia and inflammation". Cell ...
These glial cells, usually astrocytes, absorb the excess neurotransmitters. Astrocytes, a type of glial cell in the brain, ... This bidirectional communication between astrocytes and neurons add complexity to brain signaling, with implications for brain ... By regulating extracellular neurotransmitter levels, astrocytes help maintain proper synaptic function. ...
GS, in the brain, is found primarily in astrocytes. Astrocytes protect neurons against excitotoxicity by taking up excess ... Another perspective is that astrocyte swelling is due to glutamine accumulation. To prevent increased levels of cortical ... March 1996). "Inhibition of glutamine synthetase reduces ammonia-induced astrocyte swelling in rat". Neuroscience. 71 (2): 589- ... "In vitro differentiation of cultured human CD34+ cells into astrocytes". Neurol India. 61 (4): 383-8. doi:10.4103/0028- ...
"Transfer of mitochondria from astrocytes to neurons after stroke". Nature. 535 (7613): 551-555. Bibcode:2016Natur.535..551H. ...
There is a loss of astrocytes, and sometimes also a loss of neurons and oligodendrocytes. Loss of cells other than astrocytes ... since the astrocytes are semi-selectively destroyed. The astrocytes surround the blood-brain barrier (BBB), a system ... It seems that astrocytes are spared in these cases. The second most frequent autoantibody in NMO is MOG-IgG, which targets ... Within astrocytes, AQP4 is primarily found in astrocytic foot processes that abut blood vessels and the linings of the brain ( ...
Giacomelli S, Leone MG, Grima J, Silvestrini B, Cheng CY (Feb 1996). "Astrocytes synthesize and secrete prostaglandin D ...
Fluorescence images of human glioblastoma (GBM) cells (green; GFP-expressing cells) and normal human astrocytes (NHA) (red; ...
"Tropism of SARS-CoV-2 for human cortical astrocytes". Proc Natl Acad Sci USA. 119 (30): e2122236119. doi:10.1073/pnas. ... of the United States National Academy of Sciences that shows the tropism of SARS-CoV-2 for human cortical astrocytes. Mostajo- ...
They are also present on both astrocytes and oligodendrocytes. Ionotropic and metabotropic glutamate receptors, with the ... Furthermore, brain slices show glutamate receptors are ubiquitously expressed in both developing and mature astrocytes and ... in affected neurons and astrocytes, and depolarization increases downstream synaptic release of glutamate. In addition, cell ...