... and D-aspartic acid-activating enzyme. Staudenbauer W, Strominger JL (1972). "Activation of D-aspartic acid for incorporation ... Staudenbauer W, Willoughby E, Strominger JL (1972). "Further studies of the D-aspartic acid-activating enzyme of Streptococcus ... the D-aspartate ligase responsible for the addition of D-aspartic acid onto the peptidoglycan precursor of Enterococcus faecium ... This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-ammonia (or amine) ...

... versatile disulfide-reducing agent from aspartic acid". Journal of the American Chemical Society. 134 (9): 4057-9. doi:10.1021/ ... The presence of EDTA (ethylenediaminetetraacetic acid) to chelate divalent metal ions (Fe2+, Cu2+ and others) considerably ...

"Homoserine as an Aspartic Acid Precursor for Synthesis of Proteoglycan Glycopeptide Containing Aspartic Acid and a Sulfated ... or citric acid cycle (Krebs cycle), and the aspartate metabolic pathway. It forms by two reductions of aspartic acid via the ... A Synthesis of l -Homoserine from l -Aspartic Acid". Agricultural and Biological Chemistry. 25 (9): 678-679. doi:10.1080/ ... L-Homoserine is not one of the common amino acids encoded by DNA. It differs from the proteinogenic amino acid serine by ...

Versatile Disulfide-Reducing Agent from Aspartic Acid". Journal of the American Chemical Society. American Chemical Society ( ...

Aspartic acid is produced by the addition of ammonia to fumarate using a lyase. Annigan, Jan. "How Many Amino Acids Does the ... The aspartate pathway uses L-aspartic acid as the precursor for the biosynthesis of one fourth of the building block amino ... As a sidenote, AK-III catalyzes the phosphorylation of aspartic acid that is the committed step in this biosynthetic pathway. ... In plants and microorganisms, threonine is synthesized from aspartic acid via α-aspartyl-semialdehyde and homoserine. ...

Substitution of asparagine for aspartic acid in the 288. position leads to 10-fold reduction in the ability to recognize ... These amino acids are not present in DC-SIGN. Langerin is expressed in LCs which are located in the epidermis and in vaginal ... All the binding sites are flanked by positively charged amino acids (K299 and K313) which enable binding of negatively charged ...

It contains a catalytic dyad using serine-aspartic acid. ATGL catalyses the first reaction of lipolysis. It hydrolysis ... doi:10.1016/b978-0-12-386456-7.04408-7. ISBN 978-0-12-386457-4. Lehner R, Quiroga AD (2016). "Chapter 5 - Fatty Acid Handling ... May 2006). "The ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes". Diabetes. 55 (5): 1270-5. ... Fatty Acids and Mitochondria.". In Brady ST, Siegel GJ, Albers RW, Price DL (eds.). Basic Neurochemistry (Eighth ed.). New York ...

Kazakova OW; Kariakina, T. I.; Weinova, M. K.; Sidelnikova, L. I.; Kazakova, O. W. (1981). "The synthesis of aspartic acid in ...

... aspartic acid, and anthranilic acid. Nicotinic acid can be synthesized from tryptophan or aspartic acid. Ways of alkaloid ... Compounds like amino acid peptides, proteins, nucleotides, nucleic acid, amines, and antibiotics are usually not called ... Those originate from the amino acid phenylalanine, but acquire their nitrogen atom not from the amino acid but through ... they would therefore find their place before plant acids (since 'Alkaloid' would precede 'Säure' (acid) but follow 'Alkalien ...

Azevedo RA (2002). "Analysis of the aspartic acid metabolic pathway using mutant genes". Amino Acids. 22 (3): 217-230. doi: ... Once the C4 carboxylic acid is reduced to an aldehyde and the C1 aldehyde is oxidized to a carboxylic acid, experiments suggest ... Likewise, (S) 2-amino-4-oxo-5-hydroxypentanoic acid (RI-331), another amino acid analog, has also been shown to inhibit HSD. ... The overall reaction reduces the C4 carboxylic acid functional group of ASA to a primary alcohol and oxidizes the C1 aldehyde ...

3-dimethylbutyric acid. The side products for the minor pathway is methanol, aspartic acid and phenylalanine. Methanol from ... The latter is a dipeptide of phenylalanine and aspartic acid. Neotame has 2 stereocenters and 4 stereoisomers. Sweetness is due ... Over 1% is excreted in urine as carnitine conjugate of 3,3-dimethylbutyric acid. Other minor metabolites form. The major ...

... that transfers the amino acid aspartic acid to a growing polypeptide chain at the ribosome site of protein synthesis during ... Mitochondrially encoded tRNA aspartic acid also known as MT-TD is a transfer RNA which in humans is encoded by the ... "MT-TD mitochondrially encoded tRNA aspartic acid [ Homo sapiens (human) ]". www.ncbi.nlm.nih.gov. "tRNA / transfer RNA , Learn ...

1998). "Autocatalytic activation of human legumain at aspartic acid residues". FEBS Lett. 438 (1-2): 114-8. doi:10.1016/S0014- ...

... asparagine is converted to aspartic acid or isoaspartic acid. Glutamine is converted to glutamic acid or pyroglutamic acid (5- ... or isoaspartic acid, which is a beta amino acid (in green at bottom right). However, there is a concern that aspartic acid can ... Asparagine Aspartic acid Peptide bond Post-translational modification Clarke, S (2003). "Aging as war between chemical and ... Deamidation is a chemical reaction in which an amide functional group in the side chain of the amino acids asparagine or ...

For example, aspartic acid is chemically similar to phospho-serine. Therefore, when an aspartic acid replaces a serine, it is a ... but when serine amino acid residues were mutated to aspartic acid, the activity increased 90-fold. Phosphomimetics are commonly ... However some non-phosphorylated amino acids appear chemically similar to phosphorylated amino acids. Therefore, by replacing an ... with an aspartic acid (which would not need to be phosphorylated). In a laboratory setting, the use of recombinant proteins to ...

Aspartic acid (D) by alanine (A) in the 109th position Aspartic acid (D) by arginine (R) in the 109th position. It is important ... Aspartic acid (D) by alanine (A) in the 108th position. Glutamic acid (E) by alanine (A) in the 115th and 117th position. In ... Aspartic acid (D) by glutamic acid (E) in the 157th position. Nevertheless, not always a mutation due to a substitution of one ... and aspartic acid 157 (D157). ATAT1 presents seven different isoforms due to alternative splicing, a process which consists in ...

The molecule is a tetracarboxylic acid with four -COOH groups. One section of the molecule is the amino acid aspartic acid. ... and isoserine with aspartic acid is formed. Titration reveals changes in ionisation at pK 3.5 and 4.5 due to carboxylic acid ... Hydrolysis produces L-aspartic acid and racemic[why?] 2,3-diaminopropionic acid. Even though the precursor component is chiral ... 2,3-diaminopropionic acid easily racemizes in acid. Aspergillomarasmine A has [α]20°D at pH 7 of -48°. With nitrous acid ...

... and Aspartic acid. It has one negative charge cluster from amino acid 67-82. No repeats are identified. The same patterns are ... The TMEM251 protein is 169 amino acids in length. The molecular weight of this protein is 18,747 Daltons, with an isoelectric ... 8.9% turns It is predicted to have two transmembrane helices, of 23 amino acids in length each. The average hydrophobicity is ... The TMEM251 protein contains a domain of unknown function, part of the domain family DUF4583, spanning from amino acids 35-160 ...

Aspartatic acid stimulates the NMDA receptor. Aspartic acid Lithium (medication) Müller-Oerlinghausen B, Imiela M (June 1986 ... Lithium aspartate (C4H6LiNO4) is a salt of aspartic acid and lithium. It is sometimes marketed as a dietary supplement used in ...

The main amino acids involved are serine, histidine, and aspartic acid. They all play a role in cleaving the peptide bond. ... These amino acids are known as non-essential amino acids. Essential amino acids require intermediates not present in the human ... Essential amino acids must be consumed and are made in other organisms. The amino acids are joined by peptide bonds making a ... A peptide bond forms between the amino acid attached to the tRNA in the P site and the amino acid attached to a tRNA in the A ...

Aspartame is a methyl ester of the aspartic acid/phenylalanine dipeptide. Potential health risks have been examined and ...

These five are alanine, aspartic acid, asparagine, glutamic acid and serine. There are six conditionally essential amino acids ... When amino acids are in excess of needs, the liver takes up the amino acids and deaminates them, a process converting the ... There, most of the peptides are broken into single amino acids. Absorption of the amino acids and their derivatives into which ... When broken down into amino acids, they are used as precursors to nucleic acid, co-enzymes, hormones, immune response, cellular ...

The aspartic acid (D) residue is phosphorylated during the transport cycles. The SEHPL motif only exists in heavy metal ... Then ATP7A is phosphorylated at the key aspartic acid (D) residue in the highly conserved DKTG motif, accompanied by Cu(I) ... which catalyze auto-phosphorylation of a key conserved aspartic acid (D) residue within the enzyme. The first step is ATP ... The encoded ATP7A protein has 1,500 amino acids. At least 12 disease-causing mutations in this gene have been discovered. ...

The molecular weight of TMEM176B is 29.1 kiloDaltons (kdal). The protein is rich in valine and poor in aspartic acid. There are ... Isoform A variant 1 has 1444 nucleotides that encode 270 amino acids. There are 17 alternatively spliced variants with 1 ...

Self-Organization of a Polymerizable Bolaamphiphile Bearing a Diacetylene Group and L-Aspartic Acid Group. Langmuir (2009), 25( ... Self-Organization of Bolaamphiphile Bearing Biphenyl Mesogen and Aspartic-Acid Headgroups. Journal of Physical Chemistry C ( ... Aggregation behavior of an amino acid-derived bolaamphiphile and a conventional surfactant mixed system. Journal of Colloid and ...

The aspartic acid side chain has a pKa of approximately 4. In an acidic environment, this residue will readily give up its ... Acid phosphatase Prostatic acid phosphatase Lysophosphatidic acid Lipid metabolism Tartrate-resistant acid phosphatase Alkaline ... This is evidence that the active site requires this "claw" to hold on to the phosphate group, the aspartic acid residue to ... Soon after the deprotonation of the histidine residue and the protonation of the aspartic acid residue, the histidine residue ...

... ligand recognition and regulation of leucine-aspartic acid (LD) motifs". Biochemical Journal. 460 (3): 317-329. doi:10.1042/ ...

Citric acid cycle Malate-aspartate shuttle Krebs, HA; Bellamy D (1960). "The interconversion of glutamic acid and aspartic acid ... The fatty acids can be used for phospholipid synthesis or can be released. Fatty acids represent an effective storage vehicle ... Due to the truncation of the citric acid cycle the amount of acetyl-CoA infiltrated in the citric acid cycle is low and acetyl- ... Glutamate and fatty acids are immunosuppressive. The release of both metabolites may protect tumor cells from immune attacks. ...

... aspartic acid, and aminobutyric acid. The most resistant were alanine, valine, glycine, and aminoisobutyric acid. The results ... phthalic acid, phthalic acid in the presence of a mineral phase, and mellitic acid). Their half-lives were between 50 and 150 h ... The most altered compounds were the dipeptides and aspartic acid while the most robust were compounds with a hydrocarbon chain ... Exposure of aminoacids: amino acids and a dipeptide in pure form and embedded in meteorite powder were exposed to outer space. ...

Fukasawa KM, Hirose J, Hata T, Ono Y (2006). "Aspartic acid 405 contributes to the substrate specificity of aminopeptidase B". ...