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*  Aspartate transaminase
... (AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or serum glutamic oxaloacetic ... Aspartate transaminase catalyzes the interconversion of aspartate and α-ketoglutarate to oxaloacetate and glutamate. Aspartate ... Okamoto A, Kato R, Masui R, Yamagishi A, Oshima T, Kuramitsu S (1996). "An aspartate aminotransferase from an extremely ... 1984). "Mechanism of action of aspartate aminotransferase proposed on the basis of its spatial structure". J Mol Biol. 174 (3 ...
*  Liver function tests
... also called serum glutamic oxaloacetic transaminase or aspartate aminotransferase, is similar to ALT in that it is another ...
*  Aspartate-prephenate aminotransferase
... prephenate aspartate aminotransferase, and L-aspartate:prephenate aminotransferase. De-Eknamkul W, Ellis BE (1988). " ... In enzymology, an aspartate-prephenate aminotransferase (EC 2.6.1.78) is an enzyme that catalyzes the chemical reaction L- ... The systematic name of this enzyme class is L-arogenate:oxaloacetate aminotransferase. Other names in common use include ... whereas its two products are prephenate and L-aspartate. This enzyme belongs to the family of transferases, specifically the ...
*  GOT1
... aspartate aminotransferase 1)". Panteghini M (1990). "Aspartate aminotransferase isoenzymes". Clin. Biochem. 23 (4): 311-9. doi ... Totan A, Greabu M, Totan C, Spinu T (2006). "Salivary aspartate aminotransferase, alanine aminotransferase and alkaline ... Aspartate aminotransferase, cytoplasmic is an enzyme that in humans is encoded by the GOT1 gene. Glutamic-oxaloacetic ... Doyle JM, Schininà ME, Bossa F, Doonan S (1990). "The amino acid sequence of cytosolic aspartate aminotransferase from human ...
*  Aminooxyacetic acid
... inhibits aspartate aminotransferase, another PLP-dependent enzyme, which is an essential part of the malate ... Also, the inhibition of aspartate aminotransferase by aminooxyacetic acid has clinical implications for the treatment of breast ... Moreover, selective inhibition of aspartate aminotransferase with aminooxyacetic acid ameliorated experimental autoimmune ... "Targeting aspartate aminotransferase in breast cancer". Breast Cancer Research. 10 (5): R84. doi:10.1186/bcr2154. PMC 2614520 ...
*  HELLP syndrome
... aspartate aminotransferase] and/or ALT [alanine aminotransferase] ≥70 IU/l), and evidence suggestive of hemolysis (total serum ... serum aspartate aminotransferase >70 IU/l; and platelet count 50,000 and ≤100,000 cells/μl, and class 3 HELLP syndrome featured ...
*  Streptomyces violaceochromogenes
"Cytosolic aspartate aminotransferase inactivating-enzyme from Streptomyces violaceochromogenes". Agricultural and Biological ...
*  Malate-aspartate shuttle
... aspartate is converted by cytosolic aspartate aminotransferase to oxaloacetate. The net effect of the malate-aspartate shuttle ... by mitochondrial aspartate aminotransferase. Since aspartate is an amino acid, an amino radical needs to be added to the ... aspartate aminotransferase in the mitochondrial matrix and intermembrane space. malate-alpha-ketoglutarate antiporter in the ... glutamate-aspartate antiporter in the inner membrane. The primary enzyme in the malate-aspartate shuttle is malate ...
*  GOT2
Aspartate aminotransferase, mitochondrial is an enzyme that in humans is encoded by the GOT2 gene. Glutamic-oxaloacetic ... Guidetti P, Amori L, Sapko MT, Okuno E, Schwarcz R (Jul 2007). "Mitochondrial aspartate aminotransferase: a third kynurenate- ... Furuya E, Yoshida Y, Tagawa K (May 1979). "Interaction of mitochondrial aspartate aminotransferase with negatively charged ... GOT2 converts oxaloacetate into aspartate by transamination. This aspartate as well as alpha-ketoglutarate return into the ...
*  Peptidyl-Lys metalloendopeptidase
"The primary structure of aspartate aminotransferase from pig heart muscle. Digestion with a proteinase having specificity for ...
*  Cystathionine gamma-lyase
It is also a member of the broader aspartate aminotransferase family. Like many other PLP-dependent enzymes, cystathionine ...
*  Rangelia
The alanine aminotransferase, aspartate aminotransferase and creatine kinase levels may be raised. The gamma- ...
*  Alcoholic hepatitis
... including elevated bilirubin and aminotransferases. The ratio of aspartate aminotransferase to alanine aminotransferase is ... ISBN 0-7216-7335-X. Sorbi D, Boynton J, Lindor KD (1999). "The ratio of aspartate aminotransferase to alanine aminotransferase ...
*  Ebola virus disease
... elevated levels of the liver enzymes alanine aminotransferase (ALT) and aspartate aminotransferase (AST); and abnormalities in ...
*  Amino acid
For example, aspartate aminotransferase converts glutamate and oxaloacetate to alpha-ketoglutarate and aspartate. Other ... Aspartate, glycine, and glutamine are precursors of nucleotides. However, not all of the functions of other abundant non- ... to bind to positively charged molecules have surfaces rich with negatively charged amino acids like glutamate and aspartate, ...
*  HSPA8
"Structural features of the precursor to mitochondrial aspartate aminotransferase responsible for binding to hsp70". The Journal ...
*  Alanine transaminase
... shows a marked diurnal variation.[citation needed] The ratio of ALT to AST (aspartate aminotransferase) ... determined that the appropriate terminology for AST and ALT are aspartate aminotransferase and alanine aminotransferase. The ... Aspartate transaminase Liver function tests Karmen A, Wroblewski F, Ladue JS (Jan 1955). "Transaminase activity in human blood ... Wang CS, Chang TT, Yao WJ, Wang ST, Chou P (April 2012). "Impact of increasing alanine aminotransferase levels within normal ...
*  Mitochondrial matrix
"Mechanism of action of aspartate aminotransferase proposed on the basis of its spatial structure". Journal of Molecular Biology ... These reactions are facilitated by transaminases in order to produce aspartate and asparagine from oxaloacetate. Transamination ...
*  Transferase
"Mechanism of action of aspartate aminotransferase proposed on the basis of its spatial structure". Journal of Molecular Biology ... Transamination, or the transfer of an amine (or NH2) group from an amino acid to a keto acid by an aminotransferase (also known ... In ATCase such a transfer is written as Carbamyl phosphate + L-aspertate → {\displaystyle \rightarrow } L-carbamyl aspartate + ... This includes enzymes like transaminase (also known as "aminotransferase"), and a very small number of oximinotransferases and ...
*  Hepatitis B
Aspartate aminotransferase to platelet ratio index may be used when cost is an issue. Hepatitis B virus DNA persists in the ... Carriers of the virus may have chronic hepatitis B, which would be reflected by elevated serum alanine aminotransferase (ALT) ... Chronically infected individuals with persistently elevated serum alanine aminotransferase, a marker of liver damage, and HBV ...
*  Transamination
The two common types of aminotransferases are Alanine aminotransferase (ALT) and Aspartate aminotransferase (AST). Booth, ... Glutamate + oxaloacetate ↔ α-ketoglutarate + aspartate Transamination catalyzed by aminotransferase occurs in two stages. In ... The products usually are either alanine, aspartate or glutamate, since their corresponding alpha-keto acids are produced ... For the reaction to complete, aminotransferases require participation of aldehyde containing coenzyme, pyridoxyl-5'-phosphate ( ...
*  Leptospirosis
Brief elevations of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and gamma-glutamyltransferase (GGT) ...
*  Fasciolosis
... gamma glutamyl transpeptidase and aspartate aminotransferase activities and their significance as diagnostic aids". Res. Vet. ...
*  Fibrolamellar hepatocellular carcinoma
The usual markers for liver disease - aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase - are often ...
*  Renal cell carcinoma
For example, liver enzymes such as aspartate aminotransferase [AST] and alanine aminotransferase [ALT] are found to be at ...
*  Beta-alanine-pyruvate transaminase
The systematic name of this enzyme class is L-alanine:3-oxopropanoate aminotransferase. Other names in common use include beta- ... This enzyme participates in 4 metabolic pathways: alanine and aspartate metabolism, valine, leucine and isoleucine degradation ... Stinson RA, Spencer MS (1969). "Beta alanine aminotransferase (s) from a plant source". Biochem. Biophys. Res. Commun. 34 (1): ... alanine-pyruvate aminotransferase, and beta-alanine-alpha-alanine transaminase. ...
*  Glycogen storage disease type 0
... function studies provide evidence of mild hepatocellular damage in patients with mild elevations of aspartate aminotransferase ... AST) and alanine aminotransferase (ALT) levels.[citation needed]Plasma amino-acid analysis shows plasma alanine levels as in ...