It is a dual selective estrogen receptor modulator (SERM) and aromatase inhibitor (AI), and was derived from tamoxifen, a SERM ... Aromatase inhibitors, Phenols, Selective estrogen receptor modulators, Triphenylethylenes, All stub articles, Antineoplastic ... "Design and synthesis of norendoxifen analogues with dual aromatase inhibitory and estrogen receptor modulatory activities". ...

Aromatase inhibitors, O-methylated flavanones, Phytoalexins, All stub articles, Aromatic compound stubs). ...

Aromatase inhibitors, GPER agonists, Phytoalexins, Phytoestrogens, Stilbenoids). ...

11β-Hydroxysteroid dehydrogenase inhibitors, Aromatase inhibitors, Flavanols). ...

Aromatase inhibitors, Delta-opioid receptor antagonists, Flavanones, Resorcinols, Kappa-opioid receptor antagonists, Mu-opioid ... The first theory is that naringenin inhibits aromatase, thus reducing growth of the tumor. The second mechanism proposes that ... Ho, Ping C; Saville, Dorothy J; Coville, Peter F; Wanwimolruk, Sompon (2000-04-01). "Content of CYP3A4 inhibitors, naringin, ... Nicola, Clementi; Carolina, Scagnolari; Elena, Criscuolo (2020-10-20). "Naringenin is a powerful inhibitor of SARS-CoV-2 ...

... and has been implicated in limiting the effectiveness of aromatase inhibitors in the treatment of breast cancer. As such, ... identified CYP27A1 inhibitors, including the marketed drugs anastrozole, fadrozole, bicalutamide, dexmedetomidine, ravuconazole ...

Aromatase inhibitors, Exercise physiology, Drugs in sport, All stub articles, Steroid stubs, Genito-urinary system drug stubs) ... 4-OHT has moderate anabolic, mild androgenic, and anti-aromatase properties and is similar to the steroid clostebol (4- ...

Aromatase inhibitors, Chloroarenes, Endocrine disruptors, Fungicides, Nonsteroidal antiandrogens, Pyrimidines, Xenoestrogens). ...

Aromatase inhibitors, Flavonols, Xanthine oxidase inhibitors). ... Myricetin was identified as a competitive inhibitor of the ...

Aromatase inhibitors, Hormonal antineoplastic drugs, Human drug metabolites, Prodrugs, Triphenylethylenes, All stub articles, ...

5α-Reductase inhibitors, Alkenoic acids, Aromatase inhibitors, Essential fatty acids, Essential nutrients, Fatty acids). ... are by a lipoxygenase action found to be competitive inhibitors of brain and immune cell FAAH, the enzyme that breaks down AEA ... is the first natural inhibitor of FAAH, discovered. Linoleic acid is a component of quick-drying oils, which are useful in oil ...

Aromatase inhibitors (AIs) such as aminoglutethimide, anastrozole, exemestane, letrozole, and testolactone inhibit the ... A steroidogenesis inhibitor, also known as a steroid biosynthesis inhibitor, is a type of drug which inhibits one or more of ... 7-DHCR inhibitors produce an acquired form of SLOS in animals, and as such, like 24-DHCR inhibitors (see below), are probably ... Steroidogenic enzyme Neurosteroidogenesis inhibitor Vanden Bossche H (1992). "Inhibitors of P450-dependent steroid biosynthesis ...

3β-Hydroxysteroid dehydrogenase inhibitors, Aromatase inhibitors, Chromanes, CYP3A4 inducers, Pfizer brands, CYP17A1 inhibitors ... Troglitazone use was associated with a decrease of nuclear factor kappa-B (NF-κB) and a concomitant increase in its inhibitor ( ... "Nuclear factor-kappaB suppressive and inhibitor-kappaB stimulatory effects of troglitazone in obese patients with type 2 ...

3α-Hydroxysteroid dehydrogenase inhibitors, Aromatase inhibitors, Coumestans, Phytoestrogens, Selective ERβ agonists, Phenols, ... allowing it to inhibit the activity of aromatase and 3α-hydroxysteroid dehydrogenase. These enzymes are involved in the ...

... aromatase inhibitors, and antiestrogens This signaling includes communication between the endoplasmic reticulum and ...

Craig Jordan and initial studies of aromatase inhibitors by 2005 Kettering prize recipient Angela Brodie, two important classes ...

Aromatase inhibitors, Chloroarenes, Ethers, Fungicides, Imidazole antifungals, Lanosterol 14α-demethylase inhibitors, ...

... and by extension all estrogen-like compounds and aromatase inhibitors that mimic estrogen in function will be increased in ... Bailey, D.G.; Dresser, G.K.; Bend, J.R. (June 2003). "Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 ... Seville orange juice has been reported to be a possible inhibitor of CYP3A enzymes without affecting MDR1 when taken ... Edwards, D. J.; Bernier, S. M. (1996). "Naringin and naringenin are not the primary CYP3A inhibitors in grapefruit juice". Life ...

Aromatase inhibitors, Carboxylic acids, Carotenoids, Cyclohexenes, Hoffmann-La Roche brands, Retinoids, Wikipedia medicine ...

... and as an inhibitor of enzymes in the steroidogenesis pathway such as CYP17A1 and aromatase. In accordance, it has been shown ... Aromatase inhibitors, Carboxamides, Endocrine disruptors, Fungicides, Imidazoles, Nonsteroidal antiandrogens). ... Similarly to other azole fungicides, prochloraz is an inhibitor of the enzyme lanosterol 14α-demethylase (CYP51A1), which is ...

L02BG Aromatase inhibitors) Flutamide and nilutamide are alternatives Goserelin and triptorelin are alternatives Prednisone is ... Alternatives are 4th level ATC chemical subgroup (C09AA ACE inhibitors, plain) Hydralazine is listed for use only in the acute ... C09AA ACE inhibitors, plain) (for lisinopril) and 4th level ATC chemical subgroup (C08CA Dihydropyridine derivatives) (for ... C09AA ACE inhibitors, plain) Bumetanide and torasemide are alternatives For use in high‐risk patients. Atorvastatin, ...

... enzalutamide was found to decrease serum concentrations of the aromatase inhibitors anastrozole and exemestane by 90% and 50%, ... As such, it has been described as an AR signaling inhibitor in addition to antagonist. The drug is described as a "second- ... Circulating concentrations of enzalutamide may be altered by inhibitors and inducers of CYP2C8 and CYP3A4, and should be ... inhibitor, in advanced AR+ triple-negative breast cancer (TNBC)". Cancer Research. 75 (9 Supplement): P5-19-09. doi:10.1158/ ...

Aromatase inhibitors, Hydroxyquinol ethers, Isoflavones, NADH dehydrogenase inhibitors, Mitochondrial toxins, Plant toxin ... an electron transport chain Complex III inhibitor), oligomycin (an ATP synthase inhibitor) and FCCP (a mitochondrial uncoupler ... "Mechanistic Investigations of the Mitochondrial Complex I Inhibitor Rotenone in the Context of Pharmacological and Safety ... insecticides, Respiratory toxins, Microtubule inhibitors, Neurotoxins, Isopropenyl compounds). ...

... of breast cancer in women who were previously treated with and benefited from but acquired resistance to aromatase inhibitors ... Inhibitors and inducers of cytochrome P450 may influence the metabolism of estradiol and by extension circulating estradiol ...

Aromatase inhibitors, Fatty acids, Palm oil, Alkanoic acids). ...

Acetylcholinesterase inhibitors, Amorphous solids, Antiemetics, Appetite stimulants, Aromatase inhibitors, Benzochromenes, CB1 ... Recently, it has been shown that THC is also a partial autotaxin inhibitor, with an apparent IC50 of 407 ± 67 nM for the ATX- ...

... and S-40503 Aromatase inhibitors: anastrozole, aminoglutethimide, fadrozole, finrozole, letrozole, liarozole, norendoxifen, ... rogletimide (pyridoglutethimide), vorozole Other steroidogenesis inhibitors: aminoglutethimide, ketoconazole, orteronel, ...

21-Hydroxylase inhibitors, Aromatase inhibitors, Chloroarenes, CYP3A4 inhibitors, CYP17A1 inhibitors, Phenylethanolamine ethers ... Imidazole antifungals, Lanosterol 14α-demethylase inhibitors, General cytochrome P450 inhibitors, All stub articles, ...

Research showed that orally administered chrysin does not have clinical activity as an aromatase inhibitor.Nanoformulations of ... Aromatase inhibitors, Flavones, Flavonoids found in Asteraceae, Resorcinols). ... "No evidence for the in vivo activity of aromatase-inhibiting flavonoids". The Journal of Steroid Biochemistry and Molecular ...

Aromatase inhibitors, CYP2C8 inhibitors, CYP3A4 inhibitors, Flavonoid antioxidants, GPER agonists, Xanthine oxidase inhibitors ... In-vitro studies show that quercetin is a strong inhibitor of the cytochrome P450 enzymes CYP3A4 and CYP2C19 and a moderate ... It is a naturally occurring polar auxin transport inhibitor. Quercetin is one of the most abundant dietary flavonoids, with an ... For example, it is a nonspecific protein kinase enzyme inhibitor. Quercetin, in conjunction with dasatinib, is a senolytic; the ...