Evidence for a secretin-induced vesicular translocation of aquaporin-1". The Journal of Biological Chemistry. 272 (20): 12984- ... translocation of aquaporin 2, or both are found. It has been suggested that "Secretin as a neurosecretory hormone from the ... "Secretin promotes osmotic water transport in rat cholangiocytes by increasing aquaporin-1 water channels in plasma membrane. ... 80 (2): 185-194. doi:10.1006/geno.2002.6814. PMID 12160732. Lee LT, Tan-Un KC, Chow BK (July 2006). "Retinoic acid-induced ...
Increased NKCC2 activity aids in water reabsorption in the collecting duct through aquaporin 2 channels by creating a hypo- ... 13 (2): 183-8. doi:10.1038/ng0696-183. PMID 8640224. S2CID 42296304. Plata C, Meade P, Vazquez N, Hebert SC, Gamba G (Mar 2002 ... 22 (2): 192-5. doi:10.1038/9713. PMID 10369265. S2CID 23779936. Dzhala VI, Talos DM, Sdrulla DA, Brumback AC, Mathews GC, Benke ... isoform 2) exon 21 in the final gene product. NKCC1 is widely distributed throughout the human body; it has important functions ...
Aquaporin tetramer composition modifies the function of tobacco aquaporins. Journal of Biological Chemistry, 2010. 285(41): p. ... He is known for his work on the aquaporin protein class, where he detected facilitated diffusion of CO2 in plant tissue and ... Kaldenhoff was one of the first scientists to describe plant aquaporins. He initially accomplished to analyse the function and ... For the first time, Kaldenhoff could provide evidence that an aquaporin molecule could conduct CO₂. Kaldenhoff also worked on ...
Aquaporin-2 (AQ2) sits in collecting duct and is selectively inserted into cell membranes, according to the body's needs, to ... Water present in the filtrate in the papillary duct flows through aquaporin channels out of the duct, moving passively down its ... Then the Na/K-ATPase will pump 3 Na out into the peritubular fluid and 2 K into the cell on the non-lumen side of the cell. ...
... elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression". Cell Metabolism. 10 (5): 379-91. doi:10.1016/j. ... The protein predicted from DAF-2's sequence is 35% identical to the human insulin receptor, which regulates metabolism; 34% ... Mutations in DAF-2 have been shown by Cynthia Kenyon to double the lifespan of the worms. In a 2007 episode of WNYC's Radiolab ... DAF-2 is the only member of the insulin receptor family in C. elegans but it corresponds, in form and function, to multiple ...
Molecular and Cellular Features of Aquaporin Expression". Plant Physiology. 139 (2): 790-805. doi:10.1104/pp.105.065029. PMC ... 6 (2): 275-286. doi:10.1093/mp/sst017. PMID 23355543. Boursiac, Y.; Chen, S.; Luu, D. T.; Sorieul, M.; Van Den Dries, N.; ... 128 (2): 379-387. doi:10.1104/pp.010524. PMC 148901. PMID 11842142. Babourina, O. (2000). "Effect of Sudden Salt Stress on Ion ... doi:10.1007/s00425-005-0074-2. PMID 16079998. S2CID 337766. Demidchik, V.; Tester, M. (2002). "Sodium Fluxes through ...
The increased intracellular cAMP in the kidney in turn triggers fusion of aquaporin-2-bearing vesicles with the apical plasma ...
Aquaporin 6, Serine Rich Single-Pass Membrane Protein 1, and Adrenoceptor Beta 2. Transmembrane Protein 144 arose approximately ... Homocysteine-Responsive Endoplasmic Reticulum-Resident Ubiquitin-Like Domain Member 2 Protein, Translocase of Inner ... Mitochondrial Membrane Domain-Containing Protein 1, Free Fatty Acid Receptor 2, ...
... calbindin expressed in distal tubules and aquaporin 2 expressed in the collecting duct cells. The mammalian kidney develops ... 2:23) state that God searches out and inspects the kidneys, or "reins", of humans, together with the heart. Kidney stones have ... 5 (2/3): 70-83. doi:10.4024/230503.jbpc.05.02. Maton A, Hopkins J, McLaughlin CW, Johnson S, Warner MQ, LaHart D, Wright JD ( ... 6 (1): 2. doi:10.3390/diagnostics6010002. PMC 4808817. PMID 26838799. (CC-BY 4.0) Archived 2017-10-16 at the Wayback Machine ...
... aquaporin 7, sodium iodide symporter and hydrogen potassium adenosine triphosphatase) showed reduced expression or ... 3.0.CO;2-P. PMID 9021008. Fabre A, Martinez-Vinson C, Roquelaure B, Missirian C, André N, Breton A, Lachaux A, Odul E, Colomb V ... It has 43 exons of which exons 1, 2 and 3 are non coding. The predicted molecular weight of the protein is 175.486 kiloDaltons ... This syndrome was first reported in 1982 with a report on 2 siblings, and as of 2008 there were around 25 published cases in ...
... via activation of aquaporins, the site of the ADH receptors - back into the circulation. This has two consequences. First, in ... aquaporin 2), and their insertion into the cells' luminal membranes. Excessive ADH causes an inappropriate increase in the ... "Physiology and pathophysiology of renal aquaporins". Seminars in Nephrology. 21 (3): 231-8. doi:10.1053/snep.2001.21647. PMID ... 2 (Suppl_3): iii12-iii19. doi:10.1093/ndtplus/sfp154. PMC 2762827. PMID 19881932. Ashrafian, H.; Davey, P. (2001). "A review of ...
Mershin Andrew Huxley Animal locomotion Animal locomotion on the water surface Anita Goel Antiporter Aquaporin 2 Aquaporin 3 ... Aquaporin 4 Archibald Hill Ariel Fernandez Arthropod exoskeleton Arthropod leg Avery Gilbert BEST2 BK channel Bacterial outer ... Countercurrent multiplication Crenation Crista Cyclic nucleotide-gated channel alpha 1 Cyclic nucleotide-gated channel alpha 2 ... Lloyd Hodgkin Alexander Rich Alexander van Oudenaarden Allan McLeod Cormack Alpha-3 beta-4 nicotinic receptor Alpha-4 beta-2 ...
Nicaise C, Soyfoo MS, Authelet M, De Decker R, Bataveljic D, Delporte C, Pochet R (December 2008). "Aquaporin‐4 Overexpression ... They release secretory compounds that influence the phenotype of endothelial cells and express aquaporin and potassium channels ... 2(11):e1205. doi: 10.1371/journal.pone.0001205. PMID 18030339; PMCID: PMC2075163. Winkler EA, Sengillo JD, Sullivan JS, Henkel ... 4):420-2. doi: 10.1038/nn2073. Epub 2008 Mar 16. PMID 18344992; PMCID: PMC2895310. ...
... aquaporin 6 MeSH D12.776.157.530.400.500.040.374 - aquaporin 1 MeSH D12.776.157.530.400.500.040.437 - aquaporin 2 MeSH D12.776. ... 157.530.400.500.040.468 - aquaporin 4 MeSH D12.776.157.530.400.500.040.484 - aquaporin 5 MeSH D12.776.157.530.400.500.520 - ... aquaporins MeSH D12.776.157.530.400.500.040.249 - aquaglyceroporins MeSH D12.776.157.530.400.500.040.249.500 - aquaporin 3 MeSH ... MeSH D12.776.157.057.030.124 - interferon regulatory factor-1 MeSH D12.776.157.057.030.249 - interferon regulatory factor-2 ...
... aquaporin 6 MeSH D12.776.543.550.425.730.040.374 - aquaporin 1 MeSH D12.776.543.550.425.730.040.437 - aquaporin 2 MeSH D12.776. ... aquaporin 6 MeSH D12.776.543.585.400.730.040.436 - aquaporin 1 MeSH D12.776.543.585.400.730.040.530 - aquaporin 2 MeSH D12.776. ... 543.550.425.730.040.468 - aquaporin 4 MeSH D12.776.543.550.425.730.040.484 - aquaporin 5 MeSH D12.776.543.550.425.730.520 - ... 543.585.400.730.040.577 - aquaporin 4 MeSH D12.776.543.585.400.730.040.600 - aquaporin 5 MeSH D12.776.543.585.400.730.520 - ...
NMOSD can be associated with antibodies that bind to a protein called aquaporin-4 (AQP4). Binding of the anti-AQP4 antibody ... people who are anti-aquaporin-4 or AQP4 antibody-positive. NMOSD is a rare autoimmune disease of the central nervous system ... of 116 participants with NMOSD who were anti-aquaporin-4 (AQP4) antibody positive. The trials were conducted at 62 sites in the ... including the formation of pathological autoantibodies against aquaporin-4 (AQP4), and the permeability of the blood-brain ...
Wolburg H, Noell S, Wolburg-Buchholz K, Mack A, Fallier-Becker P (April 2009). "Agrin, aquaporin-4, and astrocyte polarity as ... December 2011). "Changes in brain β-amyloid deposition and aquaporin 4 levels in response to altered agrin expression in mice ... 10 (2): 45. doi:10.3390/cancers10020045. PMC 5836077. PMID 29415512. Gan S, Yang H, Xiao T, Pan Z, Wu L (October 2020). "AGRN ... 2 (11): 791-805. doi:10.1038/35097557. PMID 11715056. S2CID 52802445. Glass DJ, Bowen DC, Stitt TN, Radziejewski C, Bruno J, ...
Lindsay, L. A., & Murphy, C. R. (2006). Redistribution of aquaporins 1 and 5 in the rat uterus is dependent on progesterone: a ... Lindsay, L. A., & Murphy, C. R. (2004). Redistribution of aquaporins in uterine epithelial cells at the time of implantation in ... Acta histochemica, 87(2), 131-136. Luxford, K. A., & Murphy, C. R. (1992). Changes in the apical microfilaments of rat uterine ... Cell and Tissue Research, 199(2), 339-348. Kennedy, T. G., & Armstrong, D. T. (1975). Loss of uterine luminal fluid in the rat ...
"Antibodies to Aquaporin 4, Myelin-Oligodendrocyte Glycoprotein, and the Glycine Receptor α1 Subunit in Patients With Isolated ... 72 (2): 241-255. doi:10.1002/ana.23577. PMID 22473710. S2CID 1024358. van Sonderen, A.; Schreurs, M. W. J.; Wirtz, P. W.; ... 77 (2): 179-189. doi:10.1212/WNL.0b013e318224afde. ISSN 0028-3878. PMC 3140073. PMID 21747075. Sonderen, Agnes van; Schreurs, ... A recent study has shown that anti-IgLON5 antibodies recognize Ig-like domain 2 as an immunogenic region and causes ...
Shanahan, CM (1999). "Aquaporin-1 is expressed by vascular smooth muscle cells and mediates rapid water transport across ... 1999 Aquaporin-1 is expressed by vascular smooth muscle cells and mediates rapid water transport across vascular cell membranes ... 2 (3): 181-96. doi:10.1016/S1380-2933(96)00046-2. PMID 9373311. "Specific binding members for human carcinoembryonic antigen, ... Chodorge, M (3 December 2018). "Engineering of a GLP-1 analogue peptide/anti-PCSK9 antibody fusion for type 2 diabetes ...
Kuchel PW (2006). "The story of the discovery of aquaporins: convergent evolution of ideas--but who got there first?". Cellular ... naming it aquaporin. In 2003 Agre would receive the Nobel Prize in Chemistry for his work. Benga and his collaborators would ... Noisy-le-Grand). 52 (7): 2-5. PMID 17543213. Andriescu, Vlad (September 19, 2013). "Cum a ratat un român premiul Nobel? ... "Personal website". Archived from the original on April 2, 2016. Retrieved November 23, 2019.{{cite web}}: CS1 maint: bot: ...
In 2005 they identified the aquaporin 4 protein as the target of the disease, and developed the first in-house test to aid in ... In more than 80% of cases, IgG autoantibodies against aquaporin-4 (anti-AQP4+) are the cause, and in 10-40% of the remaining ... In more than 80% of cases, NMO is caused by immunoglobulin G autoantibodies to aquaporin 4 (anti-AQP4), the most abundant water ... Some authors propose to use the name "autoimmune aquaporin-4 channelopathy" for these diseases, while others prefer a more ...
Zador, Zsolt; Stiver, Shirley; Wang, Vincent; Manley, Geoffrey T. (2009). "Role of Aquaporin-4 in Cerebral Edema and Stroke". ... In Beitz, Eric (ed.). Aquaporins. Handbook of Experimental Pharmacology. Vol. 190. pp. 159-70. doi:10.1007/978-3-540-79885-9_7 ... 7 (2): a020420. doi:10.1101/cshperspect.a020420. PMC 4315924. PMID 25380660. Barres, B (2008). "The Mystery and Magic of Glia: ... 63 (2): 109-15. doi:10.1002/1097-4547(20010115)63:2. 3.0.CO;2-J. PMID 11169620. S2CID 24044609. Sofroniew Michael V (2014). " ...
... s, are a group of diseases characterized by auto-antibodies against aquaporin 4. After the discovery of anti- ... Pittock SJ, Lucchinetti CF (February 2016). "Neuromyelitis optica and the evolving spectrum of autoimmune aquaporin-4 ... "autoimmune aquaporin-4 channelopathy" for these diseases, while others prefer a more generic term "AQP4-astrocytopathy" that ... "Clinical Relevance of Serum Aquaporin-4 Antibody Levels in Neuromyelitis Optica". Neurochemical Research. 38 (5): 997-1001. doi ...
Agre was recognized for his discovery of aquaporin water channels. Aquaporins are water-channel proteins that move water ... Aquaporins are "the plumbing system for cells," said Agre. Every cell is primarily water. "But the water doesn't just sit in ... The 28 kDa protein is now known as aquaporin-1 (abbreviated AQP1), the archetypal member of a large family of water channel ... Permeated by water, aquaporins are required for generation of cerebrospinal fluid, aqueous humour, tears, sweat, saliva, ...
The MIP superfamily includes three subfamilies: aquaporins, aquaglyceroporins and S-aquaporins. The aquaporins (AQPs) are water ... Aquaporin-1 (Aqp1) from the human red blood cell has been solved by electron crystallography to 3.8 Å resolution (PDB: 1FQY​). ... Aquaporins generally have the NPA motif in both halves, the glycerol facilitators generally have an NPA motif in the first ... Roles of aquaporins in human cancer have been reviewed as have their folding pathways. AQPs may act as transmembrane ...
... the situation would be similar to what happened for Devic Disease and Aquaporin-4[citation needed]. MS could be considered a ... 2 (3): 295-301. doi:10.1002/acn3.164. PMC 4369279. PMID 25815356. Jarius S, Metz I, König FB, Ruprecht K, Reindl M, Paul F, ... 29 (2): 140-8. PMID 20351670. Raymond V. Damadian and David Chu, The Possible Role of Cranio-Cervical Trauma and Abnormal CSF ... 24 (2): 105-25. doi:10.1007/s00281-002-0105-z. PMC 7079941. PMID 12503060. Zrzavy T, Hametner S, Wimmer I, Butovsky O, Weiner ...
... inhibits aquaporin 9 (AQP9) on mouse hepatocytes. Phloretin functionalized gold-nanoparticles (Pht-GNPs) were ... 11 (2): 79-88. doi:10.1111/j.1463-1326.2008.00982.x. PMID 19125776. Crespy, V.; Aprikian, O.; Morand, C.; Besson, C.; Manach, C ... Phlorizin is the 2'-glucoside of phloretin Naringin dihydrochalcone is a diglycoside of phloretin Phloretin-glucosidase ... Idris, I.; Donnelly, R. (2009). "Sodium-glucose co-transporter-2 inhibitors: An emerging new class of oral antidiabetic drug". ...
"IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel". Journal of Experimental Medicine. 202 (4 ... "Neuromyelitis optica brain lesions localized at sites of high aquaporin 4 expression". Archives of Neurology. 63 (7): 964-968. ... 157 (2): 266-272.e1. doi:10.1016/j.ajo.2013.09.019. PMC 3946999. PMID 24315290. Lennon VA, Kryzer TJ, Pittock SJ, Verkman AS, ... 22 (3): 101-2, author reply 103. doi:10.1016/j.pt.2006.01.001. PMID 16446117. Agustí A, MacNee W, Donaldson K, Cosio M (2003 ...
... aquaporin, KV1.1, rhodopsin, beta2-adrenergic receptor, and PSD-95. https://swisspalm.org/enzymes The protein palmitoylation is ... The example of substrate includes H-Ras, N-ras, R-Ras, RhoB, Cdc42 inform 2, Rab10, Galpha subunit of trimeric GTP binding ...