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*  Apoptosis
Database of proteins involved in apoptosis Apoptosis Video Apoptosis Video (WEHI on YouTube ) The Mechanisms of Apoptosis ... Apoptosis & cell surface[permanent dead link] Apoptosis & Caspase 3, The Proteolysis Map-animation Apoptosis & Caspase 8, The ... The Proteolysis Map-animation Apoptosis MiniCOPE Dictionary-list of apoptosis terms and acronyms Apoptosis (Programmed Cell ... Molecular Biology and Cell Biology Apoptosis Research Portal Apoptosis Info Apoptosis protocols, articles, news, and recent ...
*  Intrinsic apoptosis
Apoptosis is a programmed form of cell death involving the degradation of cellular constituents by a group of cysteine ... Taylor, R.C., Cullen, S.P., and Martin, S.J. (2008). Apoptosis: controlled demolition at the cellular level. Nat Rev Mol Cell ...
*  Inhibitor of apoptosis
Like any regulated process, apoptosis is subject to either activation or inhibition by a variety of chemical factors. Apoptosis ... Inhibitors of apoptosis are a group of proteins that mainly act on the intrinsic pathway that block programmed cell death, ... The Inhibitors of apoptosis proteins (IAP) are a family of functionally and structurally related proteins that serve as ... Members of the family that inhibit apoptosis include Bcl-2 itself, Bcl-XL, and Bcl-w, which possess all four of the domains. ...
*  Apoptosis-inducing factor
Apoptosis inducing factor is a flavoprotein. Apoptosis inducing factor is involved in initiating a caspase-independent pathway ... Human genes encoding apoptosis inducing factor isozymes include: AIFM1 AIFM2 AIFM3 Apoptosis Parthanatos PDB: 1M6I​; Ye H, ... Apoptosis Inducing Factor (AIF) is a protein that triggers chromatin condensation and DNA fragmentation in a cell in order to ... The X-linked inhibitor of apoptosis (XIAP) has the power to influence the half-life of AIF along with Scythe. Together, the two ...
*  UVB-induced apoptosis
The sequence of events that leads to apoptosis is multifaceted and complex. Despite the simple concept of apoptosis, the ... UVB-induced apoptosis is the programmed cell death of cells that become damaged by ultraviolet rays. This is notable in skin ... Since apoptosis is a last resort alternative, it takes the initiation of multiple other genes (ING2, p53, or Ras subfamily) ... Apoptosis is a physiological process, that promotes the active suicide of cells, resulting in an advantage, unlike necrosis ...
*  Apoptosis-antagonizing transcription factor
Overexpression of this gene interfered with MAP3K12 induced apoptosis. Apoptosis-antagonizing transcription factor has been ... "Entrez Gene: AATF apoptosis antagonizing transcription factor". Guo Q, Xie J (Feb 2004). "AATF inhibits aberrant production of ... Modulation during neuronal apoptosis". Molecular and Cellular Neurosciences. 24 (4): 1038-50. doi:10.1016/j.mcn.2003.08.002. ... Burgdorf S, Leister P, Scheidtmann KH (Apr 2004). "TSG101 interacts with apoptosis-antagonizing transcription factor and ...
*  Mitochondrial apoptosis-induced channel
The mitochondrial apoptosis-induced channel (or MAC), is an early marker of the onset of apoptosis. This ion channel is formed ... Members of the Bcl-2 protein family regulate apoptosis by controlling the formation of MAC: the pro-apoptotic members Bax and/ ... Mitochondrial Apoptosis-induced Channel". Mol. Biol. Cell. 16 (5): 2424-2432. doi:10.1091/mbc.E04-12-1111. PMC 1087246 . PMID ... high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast". J. Cell Biol. 155 ...
*  History of apoptosis research
Frontiers in cell apoptosis research. New York: Nova Science. pp. 153-171. ISBN 9781600214509. Vaux DL (April 2002). "Apoptosis ... The word apoptosis is a combination of the prefix 'apo' and the root 'ptosis'. Apo means away, off or apart. Ptosis means to ... Apoptosis is the process of programmed cell death. From its early conceptual beginnings in the 1950s, it has exploded as an ... In a signal article published in 1972, John F. Kerr, Andrew H. Wyllie and A. R. Currie, coined the term "apoptosis" in order to ...
*  Inhibitor of apoptosis domain
The inhibitor of apoptosis domain -- also known as IAP repeat, Baculovirus Inhibitor of apoptosis protein Repeat, or BIR -- is ... Silke J, Vaux DL (May 2001). "Two kinds of BIR-containing protein - inhibitors of apoptosis, or required for mitosis". J. Cell ... Proteins containing BIR are known as inhibitor of apoptosis proteins (IAPs), or BIR-containing proteins (BIRPs or BIRCs), and ... Verhagen AM, Coulson EJ, Vaux DL (2001). "Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs". Genome ...
*  Cellular apoptosis susceptibility protein
The cellular apoptosis susceptibility protein (CAS) is an exportin which in the nucleus is bound to RanGTP. Nuclear_pore#Import ... of_proteins Cellular Apoptosis Susceptibility Protein at the US National Library of Medicine Medical Subject Headings (MeSH). ...
*  P53 upregulated modulator of apoptosis
PUMA apoptosis may also be induced independently of p53 activation by other stimuli, such as oncogenic stress growth factor and ... Inhibiting PUMA induced apoptosis may be an interesting target for reducing the side effects of cancer treatments, such as ... Apoptosis Apoptosome Bcl-2 Bcl-2-associated X protein (BAX) BH3 interacting domain death agonist (BID) Caspases Cytochrome c ... Fischer SF, Vier J, Kirschnek S, Klos A, Hess S, Ying S, Häcker G (October 2004). "Chlamydia inhibit host cell apoptosis by ...
*  Cellular Inhibitor of Apoptosis Protein 1
"Cellular Inhibitor of Apoptosis Protein-1 (cIAP1) Plays a Critical Role in β-Cell Survival under Endoplasmic Reticulum Stress ... "Cellular inhibitor of apoptosis protein 1 (cIAP1) stability contributes to YM155 resistance in human gastric cancer cells". J ... When a cell is tumorous it does not cease to proliferate inhibiting the apoptosis, as a result, in cancerous cells cIAP1 is ... "Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition ...
*  Apoptosis inducing factor, mitochondria associated 3
... pylori-induced apoptosis in human gastric cancer cells mediated via the release of apoptosis-inducing factor from mitochondria ... Apoptosis inducing factor, mitochondria associated 3 is a protein that in humans is encoded by the AIFM3 gene. GRCh38: Ensembl ... Apoptosis inducing factor, mitochondria associated 3". Retrieved 2017-10-24. Xie Q, Lin T, Zhang Y, Zheng J, Bonanno JA (2005 ... induces apoptosis and enhances radiosensitivity in hypoxic human hepatoma cells in vitro". Exp. Cell Res. 318 (8): 944-54. doi: ...
*  TP53-inducible glycolysis and apoptosis regulator
It also prevents apoptosis in several ways: it reduces mitochondrial ROS levels, and it prevents apoptosis-causing protein Bax ... and also protects glioma cells against hypoxia-induced apoptosis by decreasing ROS (conferring evasion of apoptosis). TIGAR is ... TIGAR cannot prevent apoptosis via death pathways that are independent from ROS and p53. In some cells, TIGAR expression can ... When MUC-1 activity is removed, levels of TIGAR decline and cells undergo ROS-induced apoptosis. In a type of head and neck ...
*  Caspase activity and apoptosis inhibitor 1
... is a protein that in humans is encoded by the CAAP1 gene. Caspase Apoptosis GRCh38: ...
*  BMF (gene)
Lei K, Davis RJ (2003). "JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis". Proc. ... 2007). "Bmf contributes to histone deacetylase inhibitor-mediated enhancing effects on apoptosis after ionizing radiation". ... Apoptosis. 11 (8): 1349-57. doi:10.1007/s10495-006-8266-1. PMID 16830229. Schmelzle T, Mailleux AA, Overholtzer M, et al. (2007 ... which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants ...
*  ENDOG
... and AMID during apoptosis in human cells". Apoptosis. 12 (7): 1155-71. doi:10.1007/s10495-007-0061-0. PMID 17347867. ... Apoptosis has proven to be tightly interwoven with other essential cell pathways. The identification of critical control points ... Apoptosis occurs in many physiological and pathological processes. It plays an important role during embryonal development as ... It was first described as a "shrinkage necrosis", and then this term was replaced by apoptosis to emphasize its role opposite ...
*  Prostate cancer
X-linked inhibitor of apoptosis (XIAP) is hypothesized to promote prostate cancer cell survival and growth and is a target of ... Zinc inhibits NF-κB pathways, is anti-proliferative and induces apoptosis in abnormal cells. Unfortunately, oral ingestion of ... Catz SD, Johnson JL (January 2003). "BCL-2 in prostate cancer: a minireview". Apoptosis. 8 (1): 29-37. doi:10.1023/A: ... RUNX2 is a transcription factor that prevents cancer cells from undergoing apoptosis thereby contributing to the development of ...
*  Clitocine
"Clitocine targets Mcl-1 to induce drug-resistant human cancer cell apoptosis in vitro and tumor growth inhibition in vivo". ... effect of clitocine from the mushroom Leucopaxillus giganteus on human cervical cancer HeLa cells by inducing apoptosis". 262 ( ...
*  Sclareol cyclase
"Sclareol induces apoptosis in human HCT116 colon cancer cells in vitro and suppression of HCT116 tumor growth in ... immunodeficient mice". Apoptosis. 12 (4): 685-694. doi:10.1007/s10495-006-0026-8. PMID 17260186. Guo, Z.; Wagner, G.J. (1995 ...
*  PARP4
Soldani C, Scovassi AI (2003). "Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: an update". Apoptosis. 7 (4): 321-8. ...
*  SLC4A2
Apoptosis. 15 (6): 693-704. doi:10.1007/s10495-010-0477-9. PMID 20180022. Gehrig H, Müller W, Appelhans H (1992). "Complete ... "Involvement of anion exchanger-2 in apoptosis of endothelial cells induced by high glucose through an mPTP-ROS-Caspase-3 ...
*  PIAS4
... interacts with p53 and inhibits p53-mediated transactivation but not apoptosis". Apoptosis. 6 (3): 221-34. doi:10.1023/A: ...
*  AIFM2
Apoptosis-inducing factor 2 (AIFM2), also known as apoptosis-inducing factor-homologous mitochondrion-associated inducer of ... and AMID during apoptosis in human cells". Apoptosis. 12 (7): 1155-71. doi:10.1007/s10495-007-0061-0. PMID 17347867. Gong M, ... Overexpression of this gene has been shown to induce apoptosis. The expression of this gene is found to be induced by tumor ... "Entrez Gene: AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2". Gong, M; Hay, S; Marshall, KR; Munro, AW; Scrutton ...
*  Phorbol-12-myristate-13-acetate-induced protein 1
Apoptosis Apoptosome Bcl-2 Bcl-2-associated X protein (BAX) BH3 interacting domain death agonist (BID) Caspases Cytochrome c ... Armstrong JL, Veal GJ, Redfern CP, Lovat PE (2007). "Role of Noxa in p53-independent fenretinide-induced apoptosis of ... and Noxa has been shown to be involved in p53-mediated apoptosis. Noxa has been shown to interact with: BCL2-like 1, Bcl-2, and ... a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis". Science. 288 (5468): 1053-1058. doi: ...