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*  Bedaquiline
Worley, Marylee V.; Estrada, Sandy J. (2014-11-01). "Bedaquiline: A Novel Antitubercular Agent for the Treatment of Multidrug- ... Bedaquiline was described for the first time in 2004 at the Interscience Conference on Antimicrobial Agents and Chemotherapy ( ...
*  Primidone
Isoniazid, an antitubercular agent with MAOI properties, has been known to strongly inhibit the metabolism of primidone. Like ... They all had larger protective indexes than conventional agents and unlike these agents, the new ones did not cause birth ... These new agents were often described as having "innovative" and "selective" mechanisms of action; in reality, most of them ... These new agents were aggressively marketed. In 1994, felbamate became the anticonvulsant of last resort after ten people out ...
*  Pyrazinamide
Its discovery as an anti-tubercular agent was remarkable since it has no activity against tuberculosis in-vitro, due to not ... Dillon, Nicholas A.; Peterson, Nicholas D.; Feaga, Heather A.; Keiler, Kenneth C.; Baughn, Anthony D. (2017-07-21). "Anti-tubercular ... Antimicrobial Agents and Chemotherapy. 39: 1269-1271. doi:10.1128/aac.39.6.1269. Klemens, S.P.; Sharpe, C.A.; Cynamon, M.H. ( ... Antimicrobial Agents and Chemotherapy. 59 (12): 7320-7326. doi:10.1128/aac.00967-15. PMID 26369957. Shi W, Zhang X, Jiang X, ...
*  Infection
... including antitubercular), antiviral, antifungal and antiparasitic (including antiprotozoal and antihelminthic) agents. ... First, the catalog of infectious agents has grown to the point that virtually all of the significant infectious agents of the ... Second, an infectious agent must grow within the human body to cause disease; essentially it must amplify its own nucleic acids ... Not all infectious agents cause disease in all hosts. For example, less than 5% of individuals infected with polio develop ...
*  List of MeSH codes (D16)
... antitubercular MeSH D27.505.954.122.085.222 --- antitreponemal agents MeSH D27.505.954.122.085.255 --- antitubercular agents ... anti-allergic agents MeSH D27.505.954.122 --- anti-infective agents MeSH D27.505.954.122.085 --- anti-bacterial agents MeSH ... antiviral agents MeSH D27.505.954.122.388.077 --- anti-retroviral agents MeSH D27.505.954.122.388.077.088 --- anti-hiv agents ... renal agents MeSH D27.505.954.613.056 --- anti-infective agents, urinary MeSH D27.505.954.613.860 --- uricosuric agents MeSH ...
*  Leprostatic agent
Sulfone - Dapsone (DDS), Phenazine derivative - Clofazimine, Antitubercular drugs - Rifampicin, Ethionamide, Solapsone, Other ... A leprostatic agent is a drug that interferes with proliferation of the bacterium that causes leprosy. The following agents are ... Established agents used in the treatment of leprosy are dapsone, clofazimine, and rifampicin. Treatment of tuberculoid leprosy ... Dapsone, combined with other antileprosy agents like rifampicin and clofazimine, is used in the treatment of both ...
*  Proteasome accessory factor E
Mycobacterium tuberculosis (Mtb) is the etiologic agent of the disease tuberculosis, which kills approximately 1.4 million ... recent emergence of increasingly drug-resistant Mtb strains have given rise to an urgent need for the development of new anti-tubercular ...
*  Einhorn-Brunner reaction
Triazoles have been found to have a number of real world applications as antibacterial agents. The Einhorn-Brunner reaction ... Research done by Pattan et al., specifically on 1,2,4-triazoles, found antibacterial, antifungal, antitubercular, and anti- ... antitubercular and anti-inflammatory activities" (PDF). Indian Journal of Chem. 51B: 297-301. ...
*  Psychopharmacology revolution
Nevertheless related agents such as phenelzine and isocarboxazid are still on the market. In addition, tranylcypromine is a non ... Iproniazid was the result of a failed medicinal chemistry attempt to improve on the anti-tubercular activity of isoniazid. It ... A limitation of these agents is their potential to cause hypertension so their safety is not guaranteed. However, it seems that ... He noted the so-called "indifference" that this agent causes and suggested that it be used on agitated psychotic patients. ...
*  Furonazide
In vivo studies in the guinea pig showed furonazide slightly more active than isoniazid as a tuberculostatic agent. The drug ... Antitubercular compounds". Yakugaku Zasshi. 75: 1066-9. Kiichiro Kakemi; Sezaki, Hitoshi; Iwamoto, Kikuo; Sano, Yukito (1969 ...
*  SQ109
In preclinical studies SQ109 enhanced the activity of anti-tubercular drugs isoniazid and rifampin and reduced by >30% the time ... "Synthesis and evaluation of carbamate prodrugs of SQ109 as antituberculosis agents". Bioorganic & Medicinal Chemistry Letters. ... a new diamine-based antitubercular drug". British Journal of Pharmacology. 144 (1): 80-87. doi:10.1038/sj.bjp.0705984. PMC ...
*  Ethionamide
... is used in combination with other antituberculosis agents as part of a second-line regimen for active tuberculosis ... Belardinelli, Juan M.; Morbidoni, Héctor R. (2013-04-01). "Recycling and refurbishing old antitubercular drugs: the encouraging ... Rastogi, Nalin; Labrousse, Valérie; Goh, Khye Seng (1996). "In Vitro Activities of Fourteen Antimicrobial Agents Against Drug ... Bennett, John E.; Dolin, Raphael; Blaser, Martin; Mandell, Gerald L. "38 - Antimycobacterial Agents". Mandell, Douglas, and ...
*  Streptomyces isolates
A recent screening of TCM extracts revealed a Streptomyces that produces a number of antitubercular pluramycins. Biology portal ... Antimicrobial Agents and Chemotherapy. 8 (6): 721-32. doi:10.1128/AAC.8.6.721. PMC 429454 . PMID 1211926. Retrieved 2012-01-19 ... Y3111 from traditional Chinese medicine produced antitubercular pluramycins". Appl Microbiol Biotechnol. 98 (3): 1077-85. doi: ...
*  Mycolic acid
An international multi-centre study has proved that delamanid (OPC-67683), a new agent derived from the nitro-dihydro- ... Raman, K.; Rajagopalan, P.; Chandra, N. (2005). "Flux Balance Analysis of Mycolic Acid Pathway: Targets for Anti-Tubercular ... Novel inhibitors of this enzyme could potentially be used as therapeutic agents. The mycolic acids show interesting ... the causative agent of the disease tuberculosis. They form the major component of the cell wall of mycolata species. Despite ...
*  Rifampicin
... is relatively ineffective against spirochetes, which has led to its use as a selective agent capable of isolating ... Mycobacterial resistance to rifampicin may occur alone or along with resistance to other first line anti-tubercular drugs. ... Leschine, S.B.; Canale-Parola, E. (December 1980). "Rifampin as a Selective Agent for the Isolation of Oral Spirochetes" (PDF ... Antimicrobial Agents and Chemotherapy. 42: 2762-4. PMC 105936 . PMID 9756794. Pugazhenthan Thangaraju; Hosanna Singh; M Punitha ...
*  Osteomyelitis
In patients with sickle cell disease, the most common causative agent is Salmonella, with a relative incidence more than twice ... Tubercular osteomyelitis of the spine was so common before the initiation of effective antitubercular therapy, it acquired a ...
*  Beta-ketoacyl-(acyl-carrier-protein) synthase III
Agents Chemother. 48 (8): 3093-102. doi:10.1128/AAC.48.8.3093-3102.2004. PMC 478545 . PMID 15273125. Al-Balas Q, Anthony NG, Al ... Raman K, Rajagopalan P, Chandra N (October 2005). "Flux Balance Analysis of Mycolic Acid Pathway: Targets for Anti-Tubercular ... Agents Chemother. 50 (2): 519-26. doi:10.1128/AAC.50.2.519-526.2006. PMC 1366929 . PMID 16436705. Ondeyka JG, Zink DL, Young K ... the causative agent of another serious refractory problem, malaria. Given the predominance of TB in poor countries, the ...
*  Bioenhancer
It increases the bioavailability of the active agent paclitaxel used to treat cancer. The bioenhancer technology is primarily ... Dr.Atal also initiated the bioenhanced anti tubercular drug research project using Rifampicin which later resulted in ... Glycyrrhizin, a saponin of the liquorice plant, promotes the action of numerous antibiotics and the antifungal agent ... ginger and other herbal ingredients in food a lack of nutrients or insufficient effects of active agents can be prevented: ...