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*  Angiotensin II receptor blocker
When used in clinical practice, the particular agent used may vary based on the degree of response required. Some of these ... "Potential of antihypertensive drugs for the prevention and treatment of Alzheimer's disease". Expert Review of ... in addition to their eliciting anti-hypertensive effects, may be considered for the treatment of stress-related disorders. In ... less likely to develop AD than those using other antihypertensives. Losartan, irbesartan, olmesartan, candesartan, valsartan, ...
*  Biginelli reaction
Potent antihypertensive agents". J. Med. Chem. 35 (17): 3254-3263. doi:10.1021/jm00095a023. Folkers, K.; Johnson, T. B. (1933 ... antihypertensive agents, and alpha-1-a-antagonists. The reaction mechanism of the Biginelli reaction is a series of bimolecular ...
*  Mexrenone
Gyorgy Szasz; Zsuzsanna Budvari-Barany (19 December 1990). Pharmaceutical Chemistry of Antihypertensive Agents. CRC Press. pp. ... a steroidal aldosterone antagonist and antihypertensive". J. Pharmacol. Exp. Ther. 201 (3): 762-8. PMID 864608. ...
*  Spirolactone
Pharmaceutical Chemistry of Antihypertensive Agents. CRC Press. pp. 82-. ISBN 978-0-8493-4724-5. Luther, James M. (2014). "Is ...
*  SC-5233
Pharmaceutical Chemistry of Antihypertensive Agents. CRC Press. pp. 82-. ISBN 978-0-8493-4724-5. Dennis V. Cokkinos (6 November ...
*  Prorenone
Gyorgy Szasz; Zsuzsanna Budvari-Barany (19 December 1990). Pharmaceutical Chemistry of Antihypertensive Agents. CRC Press. pp. ...
*  Guanadrel
... is an antihypertensive agent. It is used in the form of its sulfate. Guanadrel is a postganglionic adrenergic ... A new antihypertensive drug". JAMA. 245 (16): 1639-42. doi:10.1001/jama.1981.03310410017019. PMID 7206175. W.R. Hardie, J.E. ... blocking agent. Uptake of guanadrel and storage in sympathetic neurons occurs via the norepinephrine pump; guanadrel slowly ...
*  Butynamine
BREST AN, ONESTI G, SWARTZ C, BERLINER H, MOYER JH (June 1962). "Butynamine hydrochloride as an antihypertensive agent". ... Butynamine is a tertiary (a highly hindered) aliphatic amine which has antihypertensive effects. ...
*  Alton Sutnick
... a new antihypertensive agent, Clin. Pharmacol. Therapeutics 1964; 5: 167-173. Becker, K.L., Sutnick, A.I. Paralytic ileus ...
*  Pharmaceutical industry
Lv J, Perkovic V, Foote CV, Craig ME, Craig JC, Strippoli GF (2012). "Antihypertensive agents for preventing diabetic kidney ... Agents. 31 (3): 189-92. doi:10.1016/j.ijantimicag.2007.11.010. PMID 18248798. Abraham EP (1987). "Cephalosporins 1945-1986". ... Approximately 400 tons of these agents are manufactured each year; this is enough to put approximately 9,000,000 people to ... In the ensuring years other classes of antihypertensive drug were developed and found wide acceptance in combination therapy, ...
*  Atiprosin
... (AY-28,228) is an antihypertensive agent which acts as a selective α1-adrenergic receptor antagonist. It also ... A new class of potent antihypertensive agents". Journal of Medicinal Chemistry. 30 (2): 388-94. doi:10.1021/jm00385a022. PMID ... Oshiro G, Wojdan A, Klein M, Metcalf G (September 1987). "Antihypertensive and hypotensive actions of atiprosin (AY-28,228) in ... Prazosin Ketanserin David J. Triggle (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC. ISBN 0-412- ...
*  Metazosin
"Pharmacology of a new antihypertensive agent, metazosin (Kenosin)". Ceskoslovenska farmacie. 39 (6): 266-74. PMID 1981860. ... Metazosin is an antihypertensive alpha-adrenergic antagonist. Trcka, V; König, J; Mácová, S; Smíd, M; Helfert, I; Votavová, M; ...
*  History of hypertension
More recently angiotensin receptor blockers and renin inhibitors have also been introduced as antihypertensive agents. Esunge ... Freis ED (1974). "The Veterans Administration Cooperative Study on Antihypertensive Agents. Implications for Stroke Prevention ... new class of orally active antihypertensive agents". Science. 196 (4288): 441-4. doi:10.1126/science.191908. PMID 191908. ... In 1977 captopril, an orally active agent, was described; this led to the development of a number of other ACE inhibitors. ...
*  Olmesartan
It may be used alone or in combination with other antihypertensive agents. The U.S. Food and Drug Administration (FDA) has ... Benicar may be administered with other antihypertensive agents. Benicar may be administered with or without food. Olmesartan ... Several preparations containing olmesartan and other antihypertensives are available. Teva Pharmaceuticals produces a ...
*  Fenoldopam
... is used as an antihypertensive agent. It was approved by the Food and Drug Administration (FDA) in September 1997. ... Fenoldopam is used as an antihypertensive agent postoperatively, and also intravenously (IV) to treat a hypertensive crisis. ... Since fenoldopam is the only intravenous agent that improves renal perfusion, in theory it could be beneficial in hypertensive ...
*  Doxepin
Antihypertensive agents may have their effects mitigated by doxepin. Cotreatment with CNS depressants such as the ... Sympathomimetic agents may have their effects potentiated by TCAs like doxepin. Doxepin also may potentiate the adverse effects ... Antiarrhythmic agents may be an appropriate measure to treat cardiac arrhythmias resulting from doxepin overdose. Slow ... PMC 4027305 . In general, sedating properties of anti-depressant agents are related to antagonism of serotonin 5HT2, histamines ...
*  ACE inhibitor
Current, John D. Pharmacology for Anesthetists 3: Antihypertensive Agents. p. 171. FDA Prescribing information, http://www. ... In a large clinical study, one of the agents in the ACE inhibitor class, ramipril (Altace), demonstrated an ability to reduce ... Nakamura Y, Yamamoto N, Sakai K, Takano T (1995). "Antihypertensive effect of sour milk and peptides isolated from it that are ... The combination therapy of angiotensin II receptor antagonists with ACE inhibitors may be superior to either agent alone. This ...
*  Moxonidine
"Metabolism and Disposition of the Antihypertensive Agent Moxonidine in Humans" (PDF). Drug Metabolism and Disposition: the ... Moxonidine (INN) is a new-generation centrally acting antihypertensive drug licensed for the treatment of mild to moderate ... Compared to the older central-acting antihypertensives, moxonidine binds with much greater affinity to the imidazoline I1- ...
*  Lidanserin
It was developed as an antihypertensive agent but was never marketed. Ketanserin Richard C. Allen (1989). Annual Reports in ...
*  Hydracarbazine
... is a pyridazine that has found use as an antihypertensive agent. Liberman, D.; Rouaix, A.; Bull. Soc. Chim. Fr. ...
*  Quinazosin
"Leukocyte and bone marrow effects of a thiomorpholine quinazosin antihypertensive agent". Toxicology and Applied Pharmacology. ... Quinazosin is an antihypertensive adrenoreceptor antagonist. Martin, RA; Barsoum, NJ; Sturgess, JM; De La Iglesia, FA (1985). " ...
*  Pre-eclampsia
Evidence does not support the use of one anti-hypertensive over another. The choice of which agent to use should be based on ... Labetolol, Hydralazine and Nifedipine are commonly used antihypertensive agents for hypertension in pregnancy. ACE inhibitors ... Duley L, Henderson-Smart DJ, Meher S, King JF (2007). "Antiplatelet agents for preventing pre-eclampsia and its complications ... recommends that women with severe hypertension during pregnancy should receive treatment with anti-hypertensive agents. Severe ...
*  Treatment of Tourette syndrome
The α2-adrenergic receptor agonists (antihypertensive agents) show some efficacy in reducing tics, as well as other comorbid ... Because of the blood pressure effects, antihypertensive agents should not be discontinued suddenly. Clonidine (brand name ... This class of medication is often the first tried for tics, as the antihypertensives have a lower side effect profile than some ... Guanfacine (brand name Tenex) is another antihypertensive that is used in treating TS. Side effects can include sedation, dry ...
*  ROCK1
Experiments with Y27632 show it is a promising candidate as a therapeutic antihypertensive agent. Fasudil has been used to ...
*  Alpha-1 blocker
... alpha.1-adrenoceptor antagonists and antihypertensive agents". Journal of Medicinal Chemistry. 31 (5): 1031-1035. doi:10.1021/ ... Alpha-1 blockers (also called alpha-adrenergic blocking agents) constitute a variety of drugs that block alpha-1-adrenergic ... Because these medications may cause orthostatic hypotension, as well as low blood pressure in general, these agents may ... Since alpha-1 blockers may cause orthostatic hypotension, co-administration with antihypertensives and vasodilators must be ...
*  Tenoxicam
... anti-platelet agents and selective serotonin reuptake inhibitors (SSRIs), tacrolimus, zidovudine, and gold/penicillamine. The ... diuretics and anti-hypertensives, methotrexate, oral anti-diabetics, colestyramine, dextromethorphan, mifepristone, ...
*  Captopril
New class of orally active antihypertensive agents". Science. 196 (4288): 441-4. doi:10.1126/science.191908. PMID 191908. ... Antimicrobial Agents and Chemotherapy. 60 (1): 142-150. doi:10.1128/AAC.01335-15. ISSN 0066-4804. PMC 4704194 . PMID 26482303. ... Structures of Drosophila melanogaster Angiotensin-Converting Enzyme in Complex with Novel Inhibitors and Antihypertensive Drugs ...