Protostephanine is an alkaloid collected from Stephania japonica (Menispermaceae). Antihypertensive agent. The leaves of this ...
Potent antihypertensive agents". J. Med. Chem. 35 (17): 3254-3263. doi:10.1021/jm00095a023. PMID 1387168. Crespo, Abel; El ... antihypertensive agents, and alpha-1-a-antagonists. More recently products of the Biginelli reaction have been investigated as ...
Kosman ME (July 1975). "Evaluation of clonidine hydrochloride (Catapres). A new antihypertensive agent". JAMA. 233 (2): 174-6. ... The selective agents (atenolol, metoprolol) are preferred to the non-selective agents (propranolol). There are several ( ... These agents should be avoided whenever possible as there is upwards of seven times more beta-adrenoceptor antagonism than ... In the 1970s, the drug clonidine hydrocloride swept the market as a novel agent for hypertension; however, the reported side- ...
Szasz G, Budvari-Barany Z (19 December 1990). Pharmaceutical Chemistry of Antihypertensive Agents. CRC Press. pp. 87-. ISBN 978 ... a steroidal aldosterone antagonist and antihypertensive". The Journal of Pharmacology and Experimental Therapeutics. 201 (3): ...
... a new antihypertensive agent, Clin. Pharmacol. Therapeutics 1964; 5: 167-173. Becker, K.L., Sutnick, A.I. Paralytic ileus ...
Pharmaceutical Chemistry of Antihypertensive Agents. CRC Press. pp. 82-. ISBN 978-0-8493-4724-5. Luther, James M. (2014). "Is ...
Pharmaceutical Chemistry of Antihypertensive Agents. CRC Press. pp. 82-. ISBN 978-0-8493-4724-5. Dennis V. Cokkinos (6 November ...
Szasz G, Budvari-Barany Z (19 December 1990). Pharmaceutical Chemistry of Antihypertensive Agents. CRC Press. pp. 87-. ISBN 978 ...
... is an antihypertensive agent. It is used in the form of its sulfate. Guanadrel is a postganglionic adrenergic ... A new antihypertensive drug". JAMA. 245 (16): 1639-42. doi:10.1001/jama.1981.03310410017019. PMID 7206175. webpage on guanadrel ... blocking agent. Uptake of guanadrel and storage in sympathetic neurons occurs via the norepinephrine pump; guanadrel slowly ...
Antihypertensive agents, Amines, All stub articles, Antihypertensive agent stubs). ... BREST AN, ONESTI G, SWARTZ C, BERLINER H, MOYER JH (June 1962). "Butynamine hydrochloride as an antihypertensive agent". ... Butynamine is a tertiary (a highly hindered) aliphatic amine which has antihypertensive effects. ...
Lv J, Perkovic V, Foote CV, Craig ME, Craig JC, Strippoli GF (2012). "Antihypertensive agents for preventing diabetic kidney ... Agents. 31 (3): 189-92. doi:10.1016/j.ijantimicag.2007.11.010. PMID 18248798. Abraham EP (1987). "Cephalosporins 1945-1986". ... Approximately 400 tons of these agents are manufactured each year; this is enough to put approximately 9,000,000 people to ... In the ensuring years other classes of antihypertensive drug were developed and found wide acceptance in combination therapy, ...
... is used as an antihypertensive agent. It was approved by the Food and Drug Administration (FDA) in September 1997. ... Fenoldopam is used as an antihypertensive agent postoperatively, and also intravenously (IV) to treat a hypertensive crisis. ... Since fenoldopam is an intravenous agent with minimal adrenergic effects that improves renal perfusion, in theory it could be ...
Antihypertensive agents, Indoles, Isopropyl compounds, Piperazines, All stub articles, Antihypertensive agent stubs). ... Atiprosin (developmental code name AY-28,228) is an antihypertensive agent which acts as a selective α1-adrenergic receptor ... A new class of potent antihypertensive agents". Journal of Medicinal Chemistry. 30 (2): 388-94. doi:10.1021/jm00385a022. PMID ... Oshiro G, Wojdan A, Klein M, Metcalf G (September 1987). "Antihypertensive and hypotensive actions of atiprosin (AY-28,228) in ...
Webarchive template wayback links, Tripeptides, Antihypertensive agents). ... July 2005). "Antihypertensive effect of casein hydrolysate in a placebo-controlled study in subjects with high-normal blood ... Masuda O, Nakamura Y, Takano T (December 1996). "Antihypertensive peptides are present in aorta after oral administration of ... Boelsma E, Kloek J (March 2009). "Lactotripeptides and antihypertensive effects: a critical review". The British Journal of ...
"Pharmacology of a new antihypertensive agent, metazosin (Kenosin)". Ceskoslovenska Farmacie. 39 (6): 266-74. PMID 1981860. ... Metazosin is an antihypertensive α1-adrenergic receptor antagonist. Trcka, V; König, J; Mácová, S; Smíd, M; Helfert, I; ...
More recently angiotensin receptor blockers and renin inhibitors have also been introduced as antihypertensive agents. Esunge ... Freis ED (1974). "The Veterans Administration cooperative study on antihypertensive agents. Implications for stroke prevention ... new class of orally active antihypertensive agents". Science. 196 (4288): 441-4. Bibcode:1977Sci...196..441O. doi:10.1126/ ... In 1977 captopril, an orally active agent, was described; this led to the development of a number of other ACE inhibitors. ...
Stokes, Gordon S.; Oates, Helen F. (1982). "Blockers of the Neuromuscular Junction as Antihypertensive Agents". Hypertensive ... from adrenergic nerve terminals and are used as antihypertensives. Examples of these agents include bethanidine, bretylium, ... Most agents of this class are guanidinium compounds and have little capacity to cross the blood-brain barrier. Lukas G (1973 ...
Antihypertensive agents may have their effects mitigated by doxepin. Cotreatment with CNS depressants such as the ... Sympathomimetic agents may have their effects potentiated by TCAs like doxepin. Doxepin also may potentiate the adverse effects ... Antiarrhythmic agents may be an appropriate measure to treat cardiac arrhythmias resulting from doxepin overdose. Slow ... In general, sedating properties of anti-depressant agents are related to antagonism of serotonin 5HT2, histamines, and α-1 ...
Some antihypertensive agents are also used to treat tics; studies show variable efficacy but a lower side effect profile than ... The antihypertensives clonidine and guanfacine are typically tried first in children; they can also help with ADHD symptoms, ... The neuroleptics risperidone and aripiprazole are tried when antihypertensives are not effective, and are generally tried first ...
Kavelman, D. A.; Lewis, J. A. (1963-11-09). "Clinical Evaluation of a New Antihypertensive Agent: W583 (Mebutamate)". Canadian ... They may also enhance the fluid-retaining effect of certain anti-diabetic agents (thiazolidinediones). It is not known if they ... Carbamates have anxiolytic, muscle relaxant, anticonvulsant, hypnotic, antihypertensive, and analgesic effects. They have other ... An overview of the pros and cons for it being a neurotransmitter and/or a useful therapeutic agent". Neuroscience & ...
The antihypertensive agents are also used to treat tics; studies show variable efficacy, but a lower side effect profile than ... The α2-adrenergic receptor agonists (antihypertensive agents) show some efficacy in reducing tics, as well as other comorbid ... Because of the blood pressure effects, antihypertensive agents should not be discontinued suddenly. Clonidine (brand name ... This class of medication is often the first tried for tics, as the antihypertensives have a lower side effect profile than some ...
March 2003). "Metabolism and disposition of the antihypertensive agent moxonidine in humans". Drug Metabolism and Disposition. ... "Growth hormone secretion in response to the new centrally acting antihypertensive agent moxonidine in normal human subjects: ... a new centrally acting sympatholytic antihypertensive agent". Journal of Human Hypertension. 11 (Suppl 1): S29-S45. PMID ... Antihypertensive agents, Chloroarenes, Chloropyrimidines, Imidazolines, Phenol ethers, Pyrimidines). ...
"Leukocyte and bone marrow effects of a thiomorpholine quinazosin antihypertensive agent". Toxicology and Applied Pharmacology. ... Quinazosin is an antihypertensive α1-adrenergic receptor antagonist. Martin, RA; Barsoum, NJ; Sturgess, JM; De La Iglesia, FA ( ...
It was developed as an antihypertensive agent but was never marketed. Glemanserin Pruvanserin Roluperidone Volinanserin ... Antihypertensive agents, Ketones, Fluoroarenes, Piperidines, Pyrrolidones, All stub articles, Nervous system drug stubs). ...
Antihypertensive agents, Pyridazines, Hydrazines, Carboxamides, All stub articles, Antihypertensive agent stubs). ... Hydracarbazine is a pyridazine that has found use as an antihypertensive agent. Liberman D, Rouaix A (1959). "Hydrazino ...
It may be used alone or in combination with other antihypertensive agents. The US Food and Drug Administration (FDA) has ... Several preparations containing olmesartan and other antihypertensives are available. Teva Pharmaceuticals produces a ...
Antihypertensive+Agents at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Law M, Wald N, Morris J (2003 ... Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy ... necessitating antihypertensive treatment. However, current data concerning the safety of in utero exposure to antihypertensive ... "Diuretic versus alpha-blocker as first-step antihypertensive therapy: final results from the Antihypertensive and Lipid- ...
Pool, J. L. (1991). "Combination antihypertensive therapy with terazosin and other antihypertensive agents: results of clinical ... "Combination antihypertensive therapy with terazosin and other antihypertensive agents: results of clinical trials". American ... alpha.1-adrenoceptor antagonists and antihypertensive agents". Journal of Medicinal Chemistry. 31 (5): 1031-1035. doi:10.1021/ ... They are not thought to be good as first line treatment because there are other more selective agents, although they can be ...
Evidence does not support the use of one anti-hypertensive over another. The choice of which agent to use should be based on ... Labetalol, hydralazine and nifedipine are commonly used antihypertensive agents for hypertension in pregnancy. ACE inhibitors ... Duley L, Meher S, Hunter KE, Seidler AL, Askie LM (October 2019). "Antiplatelet agents for preventing pre-eclampsia and its ... recommends that women with severe hypertension during pregnancy should receive treatment with anti-hypertensive agents. Severe ...
Hypertension caused by VEGF inhibition can usually be treated with oral antihypertensive agents. Proteinuria is common when ... Generally it is well tolerated and safe but can have adverse effects which can be intensified by chemotherapeutic agents used ... These compounds are promising anti-cancer and anti-fibrosis agents, inhibiting various protein tyrosine kinases. They have ... "Synthesis and biological evaluation of novel pazopanib derivatives as antitumor agents". Bioorganic & Medicinal Chemistry ...