LFA-1/ICAM-1 interactions have recently been shown to stimulate signaling pathways that influence T cell differentiation. LFA-1 ... "Lymphocyte function-associated antigen 1 (LFA-1): a surface antigen distinct from Lyt-2,3 that participates in T lymphocyte- ... Lymphocyte function-associated antigen 1 (LFA-1) is an integrin found on lymphocytes and other leukocytes. LFA-1 plays a key ... The antigen that bound to the monoclonal antibodies was identified as an important molecule in cellular recognition processes. ...

... stimulate the differentiation and proliferation of, and present foreign antigens to B-cells. The FD cells in FDCS may derive ... lymphocyte rich (LRHD), and lymphocyte depleted (LDHD) subtypes. EBV is found in 30% to 50% of HL cases, but occurs in ~90% of ... The lymphocytes are primarily B cells (e.g., express CD20 and CD10 markers) with rare T cells evident only in the background. ... While EBV preferentially infects B cells, it may also infect other lymphocyte types viz., CD4+ T cells (i.e. T helper cells), ...

"Structure of the gene encoding the human B lymphocyte differentiation antigen CD20 (B1)". Journal of Immunology. 142 (7): 2560- ... B-lymphocyte antigen CD20 or CD20 is expressed on the surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and ... Stamenkovic I, Seed B (June 1988). "Analysis of two cDNA clones encoding the B lymphocyte antigen CD20 (B1, Bp35), a type III ... This gene encodes a B-lymphocyte surface molecule that plays a role in the development and differentiation of B-cells into ...

It results in proliferation and differentiation of B lymphocytes and production of antibodies. TI-2 antigens can activate only ... T independent antigen elicits antibody production by B lymphocytes without T lymphocyte involvement. There are 2 distinct ... TI-1 antigens activate B-cells via Toll like receptors, which are expressed in humans on the surface of B lymphocytes after BCR ... For most protein antigens, the production of antibodies by B lymphocytes is dependent on stimulation of helper T cells. However ...

... a phosphorylated human lymphocyte differentiation and activation antigen". Eur J Immunol. 20 (11): 2417-23. doi:10.1002/eji. ... Lymphocyte-specific protein 1 is a protein that in humans is encoded by the LSP1 gene. This gene encodes an intracellular F- ... "Entrez Gene: LSP1 lymphocyte-specific protein 1". Jongstra-Bilen J, Young AJ, Chong R, Jongstra J (1990). "Human and mouse LSP1 ... 1993). "Human lymphocyte-specific pp52 gene is a member of a highly conserved dispersed family". Genomics. 15 (3): 515-20. doi: ...

"Recognition of cluster of differentiation 1 antigens by human CD4-CD8-cytolytic T lymphocytes". Nature. 341 (6241): 447-450. ... CD1+Antigen at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Mouse CD Antigen Chart Human CD Antigen ... or lipopeptide antigens. CD1 antigen binding clefts are defined by locations of named portals where antigens protrude. The main ... CD1 (cluster of differentiation 1) is a family of glycoproteins expressed on the surface of various human antigen-presenting ...

... differentiation antigens of rat lymphocytes". Cell. 12 (3): 696-703. doi:10.1016/0092-8674(77)90266-5. PMID 303545. S2CID ... Thomas ML, Barclay AN, Gagnon J, Williams AF (1985). "Purification, chain separation and sequence of the MRC OX-8 antigen, a ... Thomas ML, Barclay AN, Gagnon J, Williams AF (1985). "Evidence from cDNA clones that the rat leukocyte-common antigen (T200) ... The success linked to this work on Thy1 prompted Williams to expand the search for surface molecules on lymphocytes that could ...

In addition, PGE2 limits the immune response by preventing B-lymphocyte differentiation and their ability to present antigens. ... In terms of immunity, prostaglandins have the ability to regulate lymphocyte function. PGE2 affect T-lymphocyte formation by ... PGE2 also has roles in inhibition of cytotoxic T-cell function, cell division of T-lymphocytes, and the development of TH1 ... In addition, it can suppress an immune response by inhibiting B lymphocytes from forming into antibody-secreting plasma cells. ...

Differentiation antigens of rat lymphocytes. Alan F. Williams, Giovanni Galfrè and Cesar Milstein "Elizabeth Robertson group , ... The recirculation of lymphocytes from blood to lymph in the rat. GOWANS JL. Cell, Vol 12, 663-673, (1977)Analysis of cell ... During the 1950s Gowans pioneering work sorted out the life cycle of that cell, He showed that the small lymphocyte ... Florey suggested he should investigate the lymphocyte, a cell whose life history was at that time completely obscure. ...

The intermediate subpopulation is important for antigen presentation and T lymphocyte stimulation. Briefly, antigen ... Monocyte differentiation and antigen-presenting functions. In: Nature Reviews Immunology. doi:10.1038/nri.2017.28 Nichols, ... and presented as antigens to activate T lymphocytes, which then mount a specific immune response against the antigen. Non- ... These are phagocytosis, antigen presentation, and cytokine production. Phagocytosis is the process of uptake of microbes and ...

It is associated with agammaglobulinemia-6. The B lymphocyte antigen receptor is a multimeric complex that includes the antigen ... Cluster of differentiation GRCh38: Ensembl release 89: ENSG00000007312 - Ensembl, May 2017 GRCm38: Ensembl release 89: ... "Entrez Gene: CD79B CD79b molecule, immunoglobulin-associated beta". Reth M (1992). "Antigen receptors on B lymphocytes". Annu. ... PDBe-KB provides an overview of all the structure information available in the PDB for Human B-cell antigen receptor complex- ...

T-lymphocyte surface antigen Ly-9 is a protein that in humans is encoded by the LY9 gene. LY9 has also recently been designated ... Clusters of differentiation, All stub articles, Membrane protein stubs). ... "Entrez Gene: LY9 lymphocyte antigen 9". Sayós J, Martín M, Chen A, Simarro M, Howie D, Morra M, Engel P, Terhorst C (Jun 2001 ... lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological ...

... and characterization of monoclonal antibodies to the glycosyl phosphatidylinositol-anchored lymphocyte differentiation antigen ... The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of ... 5′-nucleotidase (5′-NT), also known as ecto-5′-nucleotidase or CD73 (cluster of differentiation 73), is an enzyme that in ... Cluster of differentiation Arterial calcification due to CD73 deficiency GRCh38: Ensembl release 89: ENSG00000135318 - Ensembl ...

"A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas". J. Exp. ... The same name is also used to refer to the gene which codes for the antigen. The MART-1/melan-A antigen is specific for the ... of Belgium called the gene melan-A, presumably an abbreviation for "melanocyte antigen." MART-1/melan-A is a protein antigen ... Protein melan-A also known as melanoma antigen recognized by T cells 1 or MART-1 is a protein that in humans is encoded by the ...

... lymphocytes lack homing ability during a period of sessile differentiation and cell division, and antigen specific lymphocytes ... The process of lymphocyte homing is deliberate, mediated by lymphocyte-endothelial recognition mechanisms that enable antigen- ... Organ-specific lymphocyte homing is important for antigen-specificity and in avoiding autoimmune cross-reactions. Lymphocyte ... Two other well known examples are CD34 and GLYCAM-1. B lymphocyte T lymphocyte Lymphocyte+homing+receptors at the U.S. National ...

... is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferation ... CD226 (Cluster of Differentiation 226), PTA1 (outdated term, 'platelet and T cell activation antigen 1') or DNAM-1 (DNAX ... DNAM-1 was also used in T lymphocytes with a chimeric antigen receptors (CAR) for the treatment of cancer. DNAM-1 has a ... DNAM-1 promotes lymphocyte signaling, lymphokine secretion and cytotoxicity of NK cells and cytotoxic CD8+ T lymphocytes. Cross ...

... , also known as "Myeloid Differentiation factor 2 (MD-2)," is a protein that in humans is encoded by the ... "Entrez Gene: LY96 lymphocyte antigen 96". Park BS, Song DH, Kim HM, Choi BS, Lee H, Lee JO (April 2009). "The structural basis ... Lymphocyte antigen 96 has been shown to interact with TLR 4. When LPS binds to a hydrophobic pocket in MD-2, it directly ... lymphocyte+antigen+96,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Articles with short ...

... antigens. In B lymphocytes (B cells), interferon gamma stimulates antibody class switching. All of these cells have different, ... Induced pluripotent stem cell Directed differentiation Dedifferentiation "Pluripotent". Merriam-Webster Dictionary Online. ... lymphocytes) as backup. Another example are lymphocytes called naïve T-helper cells. These cells can differentiate into many ... Dendritic cells phagocytose invaders; then they present the antigen on their surface to stimulate the acquired immune system ( ...

He is best known for his work regarding lymphocyte development, particularly the differentiation of immature CD4+8+ (double ... Singer's work is foundational in the understanding of T cells and MHC-restricted antigen recognition. Singer's work explores ...

Overview of all the structural information available in the PDB for UniProt: P33681 (T-lymphocyte activation antigen CD80) at ... The Cluster of differentiation 80 (also CD80 and B7-1) is a B7, type I membrane protein in the immunoglobulin superfamily, with ... doi:10.1016/b978-0-12-802585-7.00001-7. ISBN 978-0-12-802585-7. "CD80 - T-lymphocyte activation antigen CD80 precursor - Homo ... If the interaction between an antigen-presenting cell and a T-cell is stable enough, the T-cell can remove the CD80 from the ...

... (Cluster of Differentiation 300A) is a human gene. The CMRF35 antigen (CMRF35A; MIM 606786), which was identified by ... reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes. CMRF35H is ... Tissue Antigens. 55 (2): 101-9. doi:10.1034/j.1399-0039.2000.550201.x. PMID 10746781. Cantoni C, Bottino C, Augugliaro R, et al ... recognized by the same antibody and is distinct from CMRF35 (Green et al., 1998).[supplied by OMIM] Cluster of differentiation ...

T lymphocytes regulate the growth and differentiation of T cells and certain B cells through the release of secreted protein ... IL3 is produced by T lymphocytes and T-cell lymphomas only after stimulation with antigens, mitogens, or chemical activators ... They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells. Interleukin receptors on ... lymphocyte activating factor, mitogenic protein, T-cell replacing factor III, B-cell activating factor, B-cell differentiation ...

CAMPATH-1 antigen, also known as cluster of differentiation 52 (CD52), is a glycoprotein that in humans is encoded by the CD52 ... CD52 is present on the surface of mature lymphocytes, but not on the stem cells from which these lymphocytes were derived. It ... CD52+antigen at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Human CD52 genome location and CD52 gene ... Since it is highly negatively charged and present on sperm cells and lymphocytes, it has been conjectured that its function is ...

... cluster differentiation antigen-26) by the uterine endometrium of the ewe and cow that costimulates lymphocyte proliferation". ... In particular, sheep uterine serpin can inhibit lymphocyte and natural killer cell function in vitro and reduce natural-killer ...

... and human lymphocyte antigen class I messenger RNAs associated with colon carcinoma progression and differentiation". Cancer ... This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in ...

The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen- ... CD8a (Cluster of Differentiation 8a), is a human gene. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T ... Sukhatme VP, Sizer KC, Vollmer AC, Hunkapiller T, Parnes JR (1985). "The T cell differentiation antigen Leu-2/T8 is homologous ... a human T-cell differentiation antigen CD8 (Leu2) cDNA mapped to 2p12". Nucleic Acids Res. 14 (19): 7817. doi:10.1093/nar/14.19 ...

1992). "The antigen-specific induction of normal human lymphocytes in vitro is down-regulated by a conserved HIV p24 epitope". ... Relationship to lymphoid differentiation". J. Clin. Invest. 84 (2): 506-16. doi:10.1172/JCI114193. PMC 548910. PMID 2547833. ... 1989). "Dephosphorylation of the human T lymphocyte CD3 antigen". Eur. J. Biochem. 181 (1): 55-65. doi:10.1111/j.1432-1033.1989 ... T cell antigen receptor (TCR) is associated on the T cell surface with a complex of protein called CD3. CD3G (gamma chain) is ...

B-lymphocyte antigen CD19, also known as CD19 molecule (Cluster of Differentiation 19), B-Lymphocyte Surface Antigen B4, T-Cell ... Zhou LJ, Ord DC, Omori SA, Tedder TF (1992). "Structure of the genes encoding the CD19 antigen of human and mouse B lymphocytes ... Zhou LJ, Ord DC, Omori SA, Tedder TF (1992). "Structure of the genes encoding the CD19 antigen of human and mouse B lymphocytes ... Tedder TF, Isaacs CM (July 1989). "Isolation of cDNAs encoding the CD19 antigen of human and mouse B lymphocytes. A new member ...

... need to enter secondary lymph nodes to encounter their antigen. Central memory T-lymphocytes, which have encountered antigen, ... of L-selectin on human bone marrow progenitor cells is an early sign of cells becoming committed to lymphoid differentiation. ... Here they reside ready to proliferate upon re-encountering antigen. Effector memory T-lymphocytes do not express L-selectin, as ... Naive T-lymphocytes, which have not yet encountered their specific antigen, ...

When a cutaneous lymphocyte antigen is expressed in the skin, the CD4+ Lutzner cell travels to the epidermis and dermis layers ... This rearrangement occurs early in the differentiation process and creates novel T-cell receptors that mimic the structure of ... They are a form of T-lymphocytes that has been mutated This atypical form of T-lymphocytes contains T-cell receptors on the ... It binds to a specific antigen to initiate an immune response. T-cell antibodies bind to antigens such as virus infected cells ...

TILs can not only recognize over-expressed self/melanocyte differentiation antigens, such as Melan-A/MART-1 (melanoma-specific ... Tumor infiltrating lymphocyte entry in the public domain NCI Dictionary of Cancer Terms Lion Biotechnologies, Inc. (Lymphocytes ... "Specific lymphocyte subsets predict response to adoptive cell therapy using expanded autologous tumor-infiltrating lymphocytes ... CD8+-Enriched Autologous Tumor-infiltrating Lymphocytes Following a Lymphocyte Depleting Regimen in Metastatic Digestive Tract ...