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*  Measles virus encoding the human thyroidal sodium iodide symporter (MV-NIS)
The human CD46 antigen is known to be the functional cellular receptor for Measles virus. This type 1 integral membrane ... Dörig, R. E.; A. Marcil; A. Chopra; C. D. Richardson (1993-10-22). "The human CD46 molecule is a receptor for measles virus ( ... is an improvement over initial efforts to engineer a Measles virus to carry the soluble marker human carcinoembryonic antigen ( ...
*  List of MeSH codes (D12.776.124)
... antigens, cd46 MeSH D12.776.124.486.274.920.250 -- complement c1 inactivator proteins MeSH D12.776.124.486.274.920.250.500 -- ... antigen, b-cell MeSH D12.776.124.486.485.950.500 -- antigens, cd79 MeSH D12.776.124.790.106.050 -- alpha 1-antichymotrypsin ... antigen-antibody complex MeSH D12.776.124.486.485.114.301 -- antitoxins MeSH D12.776.124.486.485.114.301.138 -- antivenins MeSH ... antigen-antibody complex MeSH D12.776.124.790.651.114.301 -- antitoxins MeSH D12.776.124.790.651.114.301.138 -- antivenins MeSH ...
*  List of MeSH codes (D23)
... antigens, cd43 MeSH D23.050.301.264.035.145 --- antigens, cd45 MeSH D23.050.301.264.035.146 --- antigens, cd46 MeSH D23.050. ... antigens, cd43 MeSH D23.101.100.110.145 --- antigens, cd45 MeSH D23.101.100.110.146 --- antigens, cd46 MeSH D23.101.100.110.147 ... hla-a antigens MeSH D23.050.301.500.450.370.372 --- hla-a1 antigen MeSH D23.050.301.500.450.370.374 --- hla-a2 antigen MeSH ... hla-b antigens MeSH D23.050.301.500.450.380.383 --- hla-b7 antigen MeSH D23.050.301.500.450.380.385 --- hla-b8 antigen MeSH ...
*  CD46
NIH/UW entry on Atypical Hemolytic-Uremic Syndrome OMIM entries on Atypical Hemolytic-Uremic Syndrome CD46 antigen at the US ... "Entrez Gene: CD46 CD46 molecule, complement regulatory protein". Riley-Vargas RC, Gill DB, Kemper C, Liszewski MK, Atkinson JP ... CD46 complement regulatory protein also known as CD46 (cluster of differentiation 46) and Membrane Cofactor Protein is a ... As has been demonstrated for CD46 with other ligands, the CD46 protein structure is believed to linearize upon binding HHV-6. ...
*  List of MeSH codes (D12.776.543)
... antigen, t-cell, gamma-delta MeSH D12.776.543.750.705.833.124 -- antigens, cd46 MeSH D12.776.543.750.705.833.249 -- integrin ... antigen, b-cell MeSH D12.776.543.750.705.816.821.500 -- antigens, cd79 MeSH D12.776.543.750.705.816.824 -- receptors, antigen, ... antigens, cd22 MeSH D12.776.543.550.200.124 -- antigens, cd24 MeSH D12.776.543.550.200.131 -- antigens, cd31 MeSH D12.776. ... antigens, cd27 MeSH D12.776.543.750.705.852.760.072 -- antigens, cd30 MeSH D12.776.543.750.705.852.760.097 -- antigens, cd40 ...
*  Sushi domain
IFC and UMC antigens. Complement receptor type 1 (C3b/C4b receptor) (Antigen CD35) belongs to the Knops blood group system and ... CD46, CD55, CFB, CFH, CFHR1, CFHR2, CFHR3, CFHR4, CFHR5, CR1, CR1L, CR2, CSMD1, CSMD2, CSMD3, CSPG3, DAF, F13B, FHR4, GABBR1, ... Some of the proteins in this group are responsible for the molecular basis of the blood group antigens, surface markers on the ... Complement decay-accelerating factor (Antigen CD55) belongs to the Cromer blood group system and is associated with Cr(a), Dr(a ...
*  Complement control protein
The best-studied members of this family are: Complement receptor 1 (CR1 or CD35) Membrane cofactor protein (MCP or CD46) C4b- ... and unwanted material such as cell debris and antibody-antigen complexes. Most of the complement control proteins act on the ... especially CD46, DAF and CD59. This mechanism allows some tumours to evade complement action. Norman, D.G., Barlow, P.N., Baron ...
*  CD29
... Antigen at the US National Library of Medicine Medical Subject Headings (MeSH) Human ITGB1 genome location and ITGB1 gene ... CD29 has been shown to interact with ACTN1; CD46, CD9, FHL2, Filamin, FLNB, CD81, GNB2L1, ITGB1BP1, LGALS8, MAP4K4, NME1, PKC ... CD29 is an integrin unit associated with very late antigen receptors. It is known to conjoin with alpha-3 subunit to create ... Lozahic S, Christiansen D, Manié S, Gerlier D, Billard M, Boucheix C, Rubinstein E (Mar 2000). "CD46 (membrane cofactor protein ...
*  CD9
... antigen is a protein that in humans is encoded by the CD9 gene. The protein encoded by this gene is a member of the ... Lozahic S, Christiansen D, Manié S, Gerlier D, Billard M, Boucheix C, Rubinstein E (March 2000). "CD46 (membrane cofactor ... Boucheix C, Benoit P, Frachet P, Billard M, Worthington RE, Gagnon J, Uzan G (1991). "Molecular cloning of the CD9 antigen. A ... CD9 has been shown to interact with: CD117, CD29 CD46, CD49c, CD81, PTGFRN, and TSPAN4. Tetraspanin Myogenesis Fertilisation ...
*  CD151
Raph blood group system in the BGMUT blood group antigen gene mutation database Human CD151 genome location and CD151 gene ... CD151 has been shown to interact with CD46. Cluster of differentiation Tetraspanin GRCh38: Ensembl release 89: ENSG00000177697 ... "CD46 (membrane cofactor protein) associates with multiple beta1 integrins and tetraspans". Eur. J. Immunol. 30 (3): 900-7. doi: ... identifies a novel platelet surface antigen". Br. J. Haematol. 79 (2): 263-70. doi:10.1111/j.1365-2141.1991.tb04531.x. PMID ...
*  C3b
The key to the success of the complement system in clearing antigens is regulating the effects of C3b to pathogens alone and ... An example RCA is membrane cofactor protein (MCP; CD46), which is ubiquitously expressed and plays a critical role in ... Additionally, C3b molecules can attach to the Fc regions of antigen-bound antibodies leading to phagocytosis or movement to the ... C3b is potent in opsonization: tagging pathogens, immune complexes (antigen-antibody), and apoptotic cells for phagocytosis. ...
*  Xenotransplantation
Indirect xenorecognition involves the presentation of antigens from the xenograft by recipient antigen presenting cells to CD4+ ... Experiments have shown this reduces α-Gal expression by 70%. Expression of human complement regulators (CD55, CD46, and CD59) ... Antigens of phagocytosed graft cells can also be presented by the host's class I MHC molecules to CD8+ T cells. The strength of ... These antigens (foreign objects) are often treated with powerful immunosuppressive drugs that could, in turn, make the patient ...
*  CD59
1990). "The CD59 antigen is a structural homologue of murine Ly-6 antigens but lacks interferon inducibility". Eur. J. Immunol ... CD46) and decay accelerating factor (CD55)". Eur. J. Immunol. 22 (6): 1579-1585. doi:10.1002/eji.1830220635. PMID 1376264. Hahn ... CD59 Antigen at the US National Library of Medicine Medical Subject Headings (MeSH) Human CD59 genome location and CD59 gene ... 1990). "Isolation and expression of the full-length cDNA encoding CD59 antigen of human lymphocytes". DNA Cell Biol. 9 (3): 213 ...
*  Pathophysiology of multiple sclerosis
MS patients are also known to be CD46 defective, and this leads to Interleukin-10 (IL-10) deficiency, being this involved in ... F. Quintana et al., Specific Serum Antibody Patterns Detected with Antigen Arrays Are Associated to the Development of MS in ... CS1 maint: Multiple names: authors list (link) Astier AL (2008). "T-cell regulation by CD46 and its relevance in multiple ... December 2008). "Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of ...
*  TSPAN4
This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known ... 2000). "CD46 (membrane cofactor protein) associates with multiple beta1 integrins and tetraspans". Eur. J. Immunol. 30 (3): 900 ...
*  Complement system
C3b binds to antigen-associated Ig and to the microbe surface. Ability of C3b to bind to antigen-associated Ig would work ... CD46, CD55 and CD59, depending on the cell. Pathogens, in general, don't have complement regulatory proteins (there are many ... which has formed a complex with antigens. C4b and C3b are also able to bind to antigen-associated IgG or IgM, to its Fc portion ... Upon immunisation with an antigen, more of these receptors are formed, and they are then shed from the cells to circulate in ...
*  Human herpesvirus 6
As such, at least fourteen isoforms of CD46 exist, all of which bind HHV-6a. The extracellular region of CD46 contains four ... or IgM early antigen antibody assays. The majority of these studies have shown an association between CFS and active HHV-6 ... As has been demonstrated for CD46 with other ligands, the CD46 protein structure linearizes upon binding HHV-6. While their ... CD46). The CD46 protein possesses a single variable region, as a result of alternative splicing. ...
*  Primary immunodeficiency
This is carried out by using donor-derived antigen-presenting cells. These new methods have reduced culture time to 10-12 days ... CD46) deficiency Membrane attack complex inhibitor (CD59) deficiency Paroxysmal nocturnal hemoglobinuria Immunodeficiency ... recurrent infections and failure of the development of antibodies on exposure to antigens. The 1999 criteria also distinguish ... selective immunoglobulin A deficiency Specific antibody deficiency to specific antigens with normal B cell and normal Ig ...
*  Lipid raft
... endocytosis of antigen bound to the BCR and its routing to late endosomes to facilitate loading of antigen-derived peptides ... binds to human CD46 on host cell surface; all these viral receptors are located in lipid rafts or would be relocated into lipid ... T cell antigen receptor signalling, B cell antigen receptor signalling, EGF receptor signalling, insulin receptor signalling ... The process of B cell antigen receptor signalling is similar to Immunoglobulin E signalling and T-cell antigen receptor ...
*  Acrosome reaction
The contents include surface antigens necessary for binding to the egg's cell membrane, and numerous enzymes which are ... or fluoresceinated antibody such as FITC-CD46. The antibodies/lectins have a high specificity for different parts of the ... "Comparative flow cytometric analysis of the human sperm acrosome reaction using CD46 antibody and lectins". Journal of Assisted ...
*  Adenoviridae
The two currently established receptors are: CD46 for the group B human adenovirus serotypes and the coxsackievirus adenovirus ... Adenovirus dodecahedron can qualify as a potent delivery platform for foreign antigens to human myeloid dendritic cells (MDC), ... genetically engineered adenovirus vector targeted to CD40 mediates transduction of canine dendritic cells and promotes antigen- ...