"Entrez Gene: CD274 CD274 molecule". Chemnitz JM, Parry RV, Nichols KE, June CH, Riley JL (July 2004). "SHP-1 and SHP-2 ... In turn, clonal expansion of antigen-specific CD8+ T cells and/or CD4+ helper cells is propagated. The binding of PD-L1 to the ... CD274+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Overview of all the structural ... Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein ...
Antigen-activated T cells secrete CCR5 ligands (CCL2 and CCL3) to recruit natural killer (NK) cells and other innate immune ... Gene Signature : CCL5, CD27, CD274 (PD-L1), CD276 (B7-H3), CD8A, CMKLR1, CXCL9, CXCR6, HLA-DQA1, HLA-DRB1, HLA-E, IDO1, LAG3, ... They are found to express conformational epitopes, such as MHC molecules, as nonself antigens, which activates both B and T ... by antigen-presenting cells (APCs). CXCR3 expressing Th1-polarized CD4 T cells and cytotoxic T cells are recruited to the site ...
CD274; CD276; CD300A; CD300C; CD300D; CD300E; CD300LB; CD300LF; CD300LG; CD33; CD3G; CD7; CD79A; CD79B; CD80; CD83; CD86; CD8A ... IPR003596 T-cell surface antigen CD2 InterPro: IPR013285 ACAM; ACAN; ADAMTSL1; AGC1; AMICA1; BCAM; BCAN; BGP; BGPc; BT3.3; ...
Dendritic cells are antigen-presenting cells (APCs) in the mammalian immune system. In cancer treatment they aid cancer antigen ... CD274). PD-L1 on the cell surface binds to PD1 on an immune cell surface, which inhibits immune cell activity. Among PD-L1 ... Unlike CAR-T's cell surface antigens, TCR-T can recognize that larger set of intracellular antigen fragments. However, TCR-T ... Antigens can be added to the antibody and can induce the dendritic cells to mature and provide immunity to the tumor. Dendritic ...
The neoplastic B cells in PT-DLBCL also show gains and amplifications of CD274 and PDCD1LG2, which are the genes for the pro- ... Immune privileged sites are sanctuaries where abnormal antigens that occur in them, such as those that are expressed on cancer ...
Adoptive cell transfer Cancer immunotherapy Chimeric antigen receptor Immune checkpoint Pardoll DM (March 2012). "The blockade ... or CD274). PD-L1 on the cell surface binds to PD-1 on an immune cell surface, which inhibits immune cell activity. Among PD-L1 ...