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*  Antigen-presenting cell
... antigen presentation relies on other specialized signaling molecules on the surfaces of both APCs and T cells. Antigen- ... DCs present antigen to both helper and cytotoxic T cells. They can also perform cross-presentation, a process by which they ... Antigen presentation allows for specificity of adaptive immunity and can contribute to immune responses against both ... However, it has been observed that antigen presentation to CD4+ cells via MHC class II is not restricted to the classically ...
*  HLA-DOB
HLA class II histocompatibility antigen, DO beta chain is a protein that in humans is encoded by the HLA-DOB gene. HLA-DOB ... 1993). "HIV-1 envelope protein is expressed on the surface of infected cells before its processing and presentation to class II ... 1992). "DNA sequence analysis of 66 kb of the human MHC class II region encoding a cluster of genes for antigen processing". J ... 1994). "HLA class II antigens and the HIV envelope glycoprotein gp120 bind to the same face of CD4". J. Immunol. 152 (9): 4475- ...
*  HLA-DOA
HLA class II histocompatibility antigen, DO alpha chain is a protein that in humans is encoded by the HLA-DOA gene. HLA-DOA ... 1993). "HIV-1 envelope protein is expressed on the surface of infected cells before its processing and presentation to class II ... 1994). "HLA class II antigens and the HIV envelope glycoprotein gp120 bind to the same face of CD4". J. Immunol. 152 (9): 4475- ... 1991). "Interaction of CD4 with HLA class II antigens and HIV gp120". Immunogenetics. 34 (2): 121-8. doi:10.1007/BF00211424. ...
*  HLA-F
... of HLA class I and they function together in cross-presentation of exogenous antigen. Exogenous antigen binds to a structure on ... it is involved in cross-presentation of exogenous antigen. The complex HLA-F/HLA class-I OC is a ligand for a subset of KIR ( ... "HLA-F and MHC-I open conformers cooperate in a MHC-I antigen cross-presentation pathway". Journal of Immunology. 191 (4): 1567- ... Zhang X, Lin A, Zhang JG, Bao WG, Xu DP, Ruan YY, Yan WH (January 2013). "Alteration of HLA-F and HLA I antigen expression in ...
*  Tapasin
... is a MHC class I antigen-processing molecule present in the lumen of the endoplasmic reticulum. It plays an important ... Howarth M, Williams A, Tolstrup AB, Elliott T (August 2004). "Tapasin enhances MHC class I peptide presentation according to ... Tapasin has been shown to interact with: HLA-A, and TAP1 Transporter associated with antigen processing ("TAP") ENSG00000236490 ... Tissue Antigens. 52 (3): 279-81. doi:10.1111/j.1399-0039.1998.tb03044.x. PMID 9802609. El Ouakfaoui S, Heitz D, Paquin R, ...
*  MHC class I
It is in this way, the MHC class I-dependent pathway of antigen presentation, that the virus infected cells signal T-cells that ... Hewitt, E.W. (2003). "The MHC class I antigen presentation pathway: strategies for viral immune evasion". Immunology. 110 (2): ... "Exogenous antigens are processed through the endoplasmic reticulum-associated degradation (ERAD) in cross-presentation by ... Histocompatibility Antigens Class I at the US National Library of Medicine Medical Subject Headings (MeSH) MHC Class I Genes at ...
*  Antigen presentation
... protein/protein interactions and more for genes involved in antigen processing and presentation antigen presentation at the US ... Because T cells recognise only fragmented antigens displayed on cell surfaces, antigen processing must occur before the antigen ... Cross-presentation is a special case in which MHC-I molecules are able to present extracellular antigens, usually displayed ... This antigen presentation pathway enables the immune system to detect transformed or infected cells displaying peptides from ...
*  Diffuse panbronchiolitis
... "antigen presentation". The infected cells then become targets for types of cytotoxic T-cells, which kill the infected cells so ... A subset of MHC in humans is human leukocyte antigen (HLA), which controls the antigen-presenting system, as part of adaptive ... its genes and their roles in antigen presentation. 15. Pergamon. Keicho, N.; Hijikata, M. (May 2011). "Genetic predisposition ... Online Mendelian Inheritance in Man (OMIM) Human Leukocyte Antigen A -142800 Retrieved 21 September 2011. Azuma, A.; Kudoh, S ...
*  CD4+ T cells and antitumor immunity
... through activation of antigen presenting cells (APCs) and increased antigen presentation on MHC class I, as well as secretion ... This can be attributed to a number of things; CD4+ T cells respond only to presentation of antigens by MHC class II, however, ... Cancer cells, through mutation, may actually have mutations in some of the proteins involved in antigen presentation, and as ... The simplest approach involves upregulation of adhesion molecules, thus extending the presentation of antigens by APC ( ...
*  TAP1
Gobin SJ, Wilson L, Keijsers V, Van den Elsen PJ (1997). "Antigen processing and presentation by human trophoblast-derived cell ... Townsend A, Trowsdale J (1993). "The transporters associated with antigen presentation". Semin. Cell Biol. 4 (1): 53-61. doi: ... "Presentation of viral antigen controlled by a gene in the major histocompatibility complex". Nature. 345 (6274): 449-52. doi: ... "A functionally defective allele of TAP1 results in loss of MHC class I antigen presentation in a human lung cancer". Nat. Genet ...
*  TAP2
The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to ... "The transporters associated with antigen presentation". Semin. Cell Biol. 4 (1): 53-61. doi:10.1006/scel.1993.1007. PMID ... TAP2 is a gene in humans that encodes the protein Antigen peptide transporter 2. The membrane-associated protein encoded by ... WHO Nomenclature Committee for factors of the HLA system". Tissue Antigens. 39 (4): 161-73. doi:10.1111/j.1399-0039.1992. ...
*  Histiocyte
... phagocytosis and antigen presentation. Phagocytosis is the main process of macrophages and antigen presentation the main ... Their main activity is antigen presentation; they express Factor XIIIa, CD1c, and Class II Human leukocyte antigens. A subset ... Langerhans cells are antigen-presenting cells but have undergone further differentiation. Skin Langerhans cells express CD1a, ... They express LCAs (leucocyte common antigens) CD45, CD14, CD33, and CD4 (also expressed by T helper cells). These histiocytes ...
*  CD96
It may also function in antigen presentation. Alternative splicing occurs at this locus and two transcript variants encoding ...
*  Macrophage polarization
Antigen presentation is upregulated (MHC II, CD86). M2c macrophages are important for secretion of IL-10, TGF-β. They also ... specific chemokines and antigen presentation molecules). M1 macrophages are irreplaceable during acute infectious diseases and ... Ability of TAMs to present tumour-associated antigens is decreased as well as stimulation of the anti-tumour functions of T and ...
*  Transporter associated with antigen processing
Janeway CA, Travers P, Walport M, Shlomchik M (2001). "Chapter 5, Antigen Presentation to T-lymphocytes". In Janeway, Charles. ... Transporter associated with antigen processing (TAP) is a member of the ATP-binding-cassette transporter family. It delivers ... transporter associated with antigen processing (TAP) at the US National Library of Medicine Medical Subject Headings (MeSH). ... Lankat-Buttgereit B, Tampé R (2002). "The transporter associated with antigen processing: function and implications in human ...
*  Apolipoprotein E
... lipid antigen presentation facilitation (by CD1) to natural killer T cell as well as modulation of inflammation and oxidation. ... "Apolipoprotein-mediated pathways of lipid antigen presentation". Nature. 437 (7060): 906-10. doi:10.1038/nature04001. PMID ...
*  CD1E
The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. ... "Entrez Gene: CD1E CD1e molecule". Brigl M, Brenner MB (2004). "CD1: antigen presentation and T cell function". Annu. Rev. ... CD1E Antigen at the US National Library of Medicine Medical Subject Headings (MeSH) Human CD1A genome location and CD1A gene ... Yu CY, Milstein C (1990). "A physical map linking the five CD1 human thymocyte differentiation antigen genes". EMBO J. 8 (12): ...
*  CD1D
Melián A, Beckman EM, Porcelli SA, Brenner MB (1996). "Antigen presentation by CD1 and MHC-encoded class I-like molecules". ... Brigl M, Brenner MB (2004). "CD1: antigen presentation and T cell function". Annu. Rev. Immunol. 22 (1): 817-90. doi:10.1146/ ... and are involved in the presentation of lipid antigens to T cells. CD1d is the only member of the group 2 CD1 molecules. CD1d- ... iGb3, a self antigen which has been implied in iNKT selection. HS44, a synthetic amino cyclitolic ceramide analogue which has ...
*  CD1A
The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. ... Melián A, Beckman EM, Porcelli SA, Brenner MB (1996). "Antigen presentation by CD1 and MHC-encoded class I-like molecules". ... Brigl M, Brenner MB (2004). "CD1: antigen presentation and T cell function". Annu. Rev. Immunol. 22 (1): 817-90. doi:10.1146/ ... 2000). "Separate pathways for antigen presentation by CD1 molecules". Immunity. 11 (6): 743-52. doi:10.1016/S1074-7613(00)80148 ...
*  Phagosome
Savina, Ariel; Amigorena, Sebastian (October 2007). "Phagocytosis and antigen presentation in dendritic cells". Immunological ... as DCs are mainly involved in antigen presentation rather than pathogen degradation. They need to retain protein fragments of a ... Peptides from the bacteria are trafficked to the Major Histocompatibility Complex (MHC). The peptide antigens are presented to ...
*  Psychoneuroimmunology
Suppress cell adhesion, antigen presentation, chemotaxis and cytotoxicity. Increase apoptosis. Release of corticotropin- ... They found that the immune responses to innocuous antigens triggers an increase in the activity of hypothalamic neurons and ...
*  Skin immunity
Antigen presentation may occur in peripheral lymphoid tissues. The Langerhans cells, once they are activated, they rapidly ... The epidermis antigens are connected with some cells of the skin. Among them there are the APC, antigen presenting cells ( ... Once the activated lymphocytes arrive, they get in contact with the antigen, they proliferate and develop their effector ... and present the antigens to T lymphocytes in local lymphoid organs. As result, T lymphocytes express the CLA molecule. ...
*  Monocyte
These are phagocytosis, antigen presentation, and cytokine production. Phagocytosis is the process of uptake of microbes and ... This process is called antigen presentation and it leads to activation of T lymphocytes, which then mount a specific immune ... Microbial fragments that remain after such digestion can serve as antigens. The fragments can be incorporated into MHC ... response against the antigen. Other microbial products can directly activate monocytes and this leads to production of pro- ...
*  Halobacterium
Stuart, Elizabeth S.; Morshed, Fazeela; Sremac, Marinko; DasSarma, Shiladitya (15 June 2001). "Antigen presentation using novel ...
*  Gas vesicle
Stuart, E. S.; Morshed, F.; Sremac, M.; DasSarma, S. (2001-06-15). "Antigen presentation using novel particulate organelles ... Several antigens from various human pathogens have been recombined into the gvpC gene to create subunit vaccines with long- ... Potential vaccines using gas vesicle as an antigen display can be given via the mucosal route as an alternative administration ... "Haloarchaeal Gas Vesicle Nanoparticles Displaying Salmonella Antigens as a Novel Approach to Vaccine Development". Procedia in ...
*  PSMD7
... proteins are digested into peptides for MHC class I antigen presentation. To meet such complicated demands in biological ... the HIV-1 Tat protein and the 11S regulator subunit alpha is crucial for their effects on proteasome function including antigen ...
*  Phagocyte
... stimulate lymphocytes to produce antibodies by an important process called antigen presentation. Antigen presentation is a ... Mast cells express MHC class II molecules and can participate in antigen presentation; however, the mast cell's role in antigen ... After phagocytosis, macrophages and dendritic cells can also participate in antigen presentation, a process in which a ... "Antigen presentation and T cell stimulation by dendritic cells". Annu. Rev. Immunol. 20: 621-67. doi:10.1146/annurev.immunol. ...