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*  CD154
... Antigen at the US National Library of Medicine Medical Subject Headings (MeSH) Human CD40LG genome location and CD40LG ... The end-result is a B cell that is able to mass-produce specific antibodies against an antigenic target. Early evidence for ... This inflammatory reaction in endothelial cells promotes recruitment of leukocytes to lesions and may potentially promote ... B cells can present antigens to a specialized group of helper T cells called TFH cells. If an activated TFH cell recognizes the ...
*  Monoclonal antibody therapy
... adverse reactions from these antibodies may occur because of long-lasting response to antigens. Passive monoclonal antibody ... Humanised antibodies bind antigen much more weakly than the parent murine monoclonal antibody, with reported decreases in ... The advent of monoclonal antibody technology has made it possible to raise antibodies against specific antigens presented on ... Antigen 5T4 Immunotherapy Immunoconjugate Nomenclature of monoclonal antibodies List of monoclonal antibodies, including ...
*  Ouchterlony double immunodiffusion
Ouchterlony, Örjan (1949). "Antigen-antibody reactions in gels". Acta pathologica et microbiologica Scandinavica. 26 (4): 507- ... Initially at low antigen concentration, all of the antibody is contained in the precipitate. This is called the antibody-excess ... Where the two diffusion fronts meet, if any of the antibodies recognize any of the antigens, they will bind to the antigens and ... thus large aggregates or gel-like lattices of antigen and antibody are formed. Experimentally, an increasing amount of antigen ...
*  Antigen-antibody interaction
... , or antigen-antibody reaction, is a specific chemical interaction between antibodies produced by B ... of antigen-antibody reaction). There are several types of antibodies and antigens, and each antibody is capable of binding only ... "A Theory of Antibody-Antigen Reactions. I. Theory for Reactions of Multivalent Antigen with Bivalent and Univalent Antibody". ... In the blood, the antigens are specifically and with high affinity bound by antibodies to form an antigen-antibody complex. The ...
*  Turbidimetry
Immunoturbidimetry uses the classical antigen-antibody reaction. The antigen-antibody complexes are particles which can be ...
*  Gravindex
It is based on double antigen antibody reaction. The test detects the prevention of agglutination of HCG-coated latex particles ... and the other is a solution of HCG antibodies. One drop of the urine is mixed with one drop of antibody solution for one minute ... If the level of HCG is high, the HCG will bind to the antibodies, and thus no agglutination with the HCG-coated latex particles ... If the level of HCG is too low, the antibodies will remain to agglutinate the HCG-coated latex particles. If agglutination ...
*  Lab-on-a-chip
Immunoassay: detect bacteria, viruses and cancers based on antigen-antibody reactions. Ion channel screening (patch clamp) ... better process control because of a faster response of the system (e.g. thermal control for exothermic chemical reactions) ...
*  Hélio Gelli Pereira
The team also developed new methods for the study of rickettsial antigen-antibody reactions. Interference from politicians at ...
*  Angiostrongylus cantonensis
Consequently, alternative approaches to detect antigen-antibody reactions are being explored, such as Immuno-PCR. A rapid dot- ... Chye, S. -M.; Lin, S. R.; Chen, Y. L.; Chung, L. Y.; Yen, C. M. (2004). "Immuno-PCR for Detection of Antigen to Angiostrongylus ... Current methods of detecting specific antigens associated with A. cantonensis are also unreliable. ... motion Toxic by-products such as nitrogenous waste Antigens released by dead and living parasites Although the clinical disease ...
*  Bioassay
quantitative analytical method that measures absorbance of color change from antigen-antibody reaction (ex. Direct, indirect, ... HIV test also uses indirect ELISA to detect HIV antibody caused by infection. Assay Immunoassay Hoskins, W. M.; Craig, R. (1962 ... He introduced the concept of standardization by the reactions of living matter. His bioassay on diphtheria antitoxin was the ...
*  Absolute molar mass
These measurements are most often used to measure timed events like antibody-antigen reactions or protein assembly. Batch mode ...
*  Autoimmune hemolytic anemia
... which involve immune mechanisms consisting of antigen-antibody reactions. These reactions may result from unrelated antigen- ... The latter type of antigen-antibody reaction may be termed "autoimmune", and hemolytic anemias so produced are autoimmune ... antibody complexes that fix to an innocent-bystander erythrocyte, or from related antigen-antibody combinations in which the ... The antibodies are usually directed against high-incidence antigens, therefore they also commonly act on allogenic RBCs (RBCs ...
*  Örjan Ouchterlony
"Antigen-antibody reactions in gels", Acta path microbiol scand, 26: 507-515 Ouchterlony Ö (1953), "Antigen-antibody reactions ... Ouchterlony Ö (1949), Antigen-antibody reactions in gels and the practical application of this phenomenon in the laboratory ... Types of reactions in coordinated systems of diffusion", Acta path microbiol scand, 32: 231-240 "Ouchterlony Test". Enotes.com ...
*  Coombs test
... is used to detect in-vitro antibody-antigen reactions. It is used to detect very low concentrations of antibodies present in a ... Both IgM and IgG antibodies bind strongly with their antigens. IgG antibodies are most reactive at 37 °C. IgM antibodies are ... Animal anti-human antibodies will also bind to human antibodies that may be fixed onto antigens on the surface of red blood ... If the serum contains antibodies to antigens on the RBC surface, the antibodies will bind onto the surface of the RBCs. The ...
*  Plasmodium falciparum erythrocyte membrane protein 1
It is during this condition that the parasites induce an immune response (antigen-antibody reaction) and evade destruction in ... The first human RBC antigen was reported in 1986. Howard's team found that the antigens from Gambian children, who were ... The antigen was large and appeared to be different in size in different strains of P. falciparum obtained from night monkey ( ... Both antigens bind to cultured skin cancer (melanoma) cells. But the researchers failed to confirm whether or not the protein ...
*  Automated analyser
... some analysers to detect many substances by immunoassay and other reactions that employ the use of antibody-antigen reactions. ... Depending on the test, different substances can be added to the blood plasma to trigger a clotting reaction. The progress of ... When concentration of these compounds is too low to cause a measurable increase in turbidity when bound to antibody, more ...
*  Assay
Immunoassay when the response is an antigen antibody binding type reaction. Depending on the nature of the signal amplification ... antibody against blood group antigens). Quantitative assays, i.e. assays that give accurate and exact numeric quantitative ... These may simply be in the form of a narrow band-pass optical filer, or a blocking reagent in a binding reaction that prevents ... A wide range of cellular secretions (say, a specific antibody or cytokine) can be detected using the ELISA technique. The ...
*  Immune system
... who proposed the side-chain theory to explain the specificity of the antigen-antibody reaction; his contributions to the ... A B cell identifies pathogens when antibodies on its surface bind to a specific foreign antigen. This antigen/antibody complex ... secrete millions of copies of the antibody that recognizes this antigen. These antibodies circulate in blood plasma and lymph, ... antigens during a process called antigen presentation. Antigen specificity allows for the generation of responses that are ...
*  Cell biology
... specificity of the antibody-antigen reaction can be achieved. Once this complex is formed, it is identified via either a "tag" ... immunostaining requires the reaction of an antibody directed against the protein of interest within the tissue or cell. Through ... With an enzymatic tag, such as horse radish peroxidase, a chemical reaction is carried out that results in a dark color in the ... Therefore, in order for these molecules to participate in reactions, within the cell, they need to be able to cross this ...
*  Biochip
... in competitive assays an enzyme-labelled antigen is used. On antibody-antigen binding a chemiluminescence reaction produces ... In protein Biochip Array Technology, the biochip replaces the ELISA plate or cuvette as the reaction platform. The biochip is ... First, in 1983 Kary Mullis invented the polymerase chain reaction (PCR) technique, a method for amplifying DNA concentrations. ... Biochip Array Technology is a novel application of a familiar methodology, using sandwich, competitive and antibody-capture ...
*  John Forssman
... heterophile antibody) and "Forssman reaction", also referred to as a "Forssman antigen-antibody reaction". Über die Ursachen, ... He is known for discovery of the "Forssman antigen", defined as a glycolipid heterophile antigen found on tissue cells of many ... His name is also associated with the following two terms: "Forssman antibody" ( ...
*  Immunohaematology
Immunohematology, more commonly known as blood banking is a branch of hematology which studies antigen-antibody reactions and ... Their day-to-day duties include blood typing, cross-matching and antibody identification.[citation needed] Todd, C. Interview. ...
*  Charlotte Friend
... on antigen-antibody reactions During her time at Yale she frequently traveled to New York to consult with Elvin Kabat and ...
*  Morris Goodman
Upon finishing a dissertation on the antigen-antibody precipitin reaction, he went to Caltech for post-doctoral work, supported ...
*  Allan Wilson
The strength of the antibody-antigen reaction was known to be stronger between more closely related species: their innovation ... measured the strength of the immune reaction between an antigen (serum albumin) from one species and an antibody raised against ...
*  Norovirus
The ABH antigen produced is thought to act as receptors for human norovirus. Homozygous carriers of any nonsense mutation in ... Tests such as ELISA that use antibodies against a mixture of norovirus strains are available commercially, but lack specificity ... Specific diagnosis of norovirus is routinely made by polymerase chain reaction (PCR) assays or quantitative PCR assays, which ... Tan M, Hegde RS, Jiang X (2004). "The P Domain of Norovirus Capsid Protein Forms Dimer and Binds to Histo-Blood Group Antigen ...
*  ELISA
... the antigen-antibody reaction occurs. No antigen is left for the enzyme-labelled specific HIV antibodies. These antibodies ... A specific antibody is added, and binds to antigen (hence the 'sandwich': the antigen is stuck between two antibodies). This ... The labeled antigen competes for primary antibody binding sites with the sample antigen (unlabeled). The less antigen in the ... Since it is necessary to remove any unbound antibody or antigen by washing, the antibody or antigen has to be fixed to the ...