*Ketoconazole

However, ketoconazole has largely been replaced as a first-line systemic antifungal medication by other azole antifungal agents ... part 4. Synthesis and antifungal activity of ketoconazole, a new potent orally active broad-spectrum antifungal agent". Journal ... As with all azole antifungal agents, ketoconazole works principally by inhibiting the enzyme cytochrome P450 14α-demethylase ( ... Phillips RM, Rosen T (2013). "Topical Antifungal Agents". In Wolverton SE. Comprehensive Dermatologic Therapy (3rd ed.). ...

*Sudocrem

It contains a water-repellent base (consisting of oils/waxes); protective and emollient agents; antibacterial and antifungal ... agents; and a weak anesthetic. As well as nappy rash, it can also be used to treat eczema, bedsores, acne, minor burns, surface ...

*Neil A. R. Gow

Odds, Frank C.; Brown, Alistair J.P.; Gow, Neil A.R. (2003). "Antifungal agents: mechanisms of action". Trends in Microbiology ... His studies of how the cell walls of fungal pathogenic species is assembled, responds to antifungal antibiotics and is ... recognised by the human immune system directly impacts on the design and use of antifungal drugs, diagnostics and ...

*Polylysine

Hiraki, J. (1995). "Basic and applied studies on ε-polylysine". Journal of Antibacterial Antifungal Agents. 23: 349-354. Mazia ... which offers a new way to deliver therapeutic agents specifically to the sites of injury after vascular damage. In 2010, ... which can be used either as surfactants or emulsifiers in the encapsulation of water-insoluble drugs or as antimicrobial agents ...

*Infectious disease (medical specialty)

Antibiotics are used to treat bacterial infections; antiviral agents treat viral infections; and antifungal agents treat fungal ... ID specialists employ a variety of antimicrobial agents to help treat infections. The type of agent used depends on the ...

*Antifungal

Sheehan D., Hitchcock C, Sibley C. "Current and Emerging Azole Antifungal Agents". Clin Microbiol Rev. 12: 40-79. PMC 88906 . ... Kyriakidis I, Tragiannidis A, München S, Groll AH (2016). "Clinical hepatotoxicity associated with antifungal agents". Expert ... Antifungal Drugs - Detailed information on antifungals from the Fungal Guide written by R. Thomas and K. Barber. ... Aurones - have been shown to possess antifungal properties Benzoic acid - has antifungal properties, but must be combined with ...

*Terconazole

ISBN 978-0-323-09574-7. Yoshida, Y. "Cytochrome P450 of Fungi: Primary Target for Azole Antifungal Agents". Current Topics in ... Sheehan, DJ; Hitchcock, CA; Sibley, CM (January 1999). "Current and Emerging Azole Antifungal Agents". Clinical Microbiology ... In 1940, the first commercial antifungal drug was available on the market. Before this, antifungal treatments were rare and ... Terconazole is an antifungal drug used to treat vaginal yeast infection. It comes as a lotion or a suppository and disrupts the ...

*Aspergillus alabamensis

Van Der Linden, Jan W. M.; Warris, Adilia; Verweij, Paul E. (April 2011). "species intrinsically resistant to antifungal agents ... to the antifungal drug amphotericin B though it is generally thought susceptible to other antifungal drugs such as voriconazole ... Arendrup, M.C. (June 2014). "Update on antifungal resistance in Aspergillus and Candida". Clinical Microbiology and Infection. ... Resistance to Antifungal Drugs". Mycopathologia. 174 (2): 131-141. doi:10.1007/s11046-012-9526-y. Samson, R.A.; Peterson, S.W ...

*Echinocandin

"Pharmacotherapy Update - New Antifungal Agents: Additions to the Existing Armamentarium (Part 1)". Debono, M; Gordee, RS (1994 ... 2006). "Pharmacology of Systemic Antifungal Agents". Clin Infect Dis. 43 (Suppl 1): S28. doi:10.1086/504492. Boucher, HW; Groll ... "Newer systemic antifungal agents : pharmacokinetics, safety and efficacy". Drugs. 64: 1997-2020. doi:10.2165/00003495-200464180 ... Echinocandins are a new class of antifungal drugs that inhibit the synthesis of glucan in the cell wall, via noncompetitive ...

*Ethonam

... is an antifungal agent. 2-Aminotetralin () is alkylated with ethylchloroacetate to afford the glycine derivative. ... a novel type of antifungal agents". Journal of Medicinal Chemistry. 10 (6): 1160-1161. doi:10.1021/jm00318a039. PMID 6056048. ...

*Penicillium restrictum

... novel antifungal agents produced by Penicillium restrictum. I. Production, taxonomy of the producing organism and biological ...

*Cystathionine beta-lyase

Studies have linked the anti-fungal activity of several anti-fungal agents to the inhibition of cystathionine beta-lyase; ... Jastrzębowska, Kamila; Gabriel, Iwona (2015-02-01). "Inhibitors of amino acids biosynthesis as antifungal agents". Amino Acids ... leads for new antimicrobial agents and probes of enzyme structure and function". Journal of Medicinal Chemistry. 50 (4): 755- ...

*Zinc pyrithione

Ketoconazole, another antifungal agent used in shampoos. Thieme Chemistry (Hrsg.): Römpp Online. Version 3.1. Georg Thieme ... Its antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that ... Agents Chemother. 14 (1): 60-8. doi:10.1128/aac.14.1.60. PMC 352405 . PMID 28693. Leading references: Lamore SD, Cabello CM, ... When used in latex paints with water containing high amount of iron, a sequestering agent that will preferentially bind the ...

*Posaconazole

... an extended-spectrum triazole antifungal agent". Clin Ther. 29 (9): 1862-86. doi:10.1016/j.clinthera.2007.09.015. PMID 18035188 ... Posaconazole (trade name Noxafil, Posanol) is a triazole antifungal drug. Posaconazole is used to treat invasive aspergillosis ...

*Candida tropicalis

... antifungal agents are used to treat these infections. Amphotericin B deoxycholate is the most common treatment antifungal agent ... Nystatin is a type of antifungal agent used because it is not absorbed by the gastrointestinal tract. These types of agents ... Topical antifungal agents are commonly taken in 3 forms: oral suspension, ointment and powder. Oral suspension is mainly used ... Azoles are agents that can deplete ergosterol, the main component of the fungus cell wall membrane, in order to inhibit fungal ...

*Fonsecaea pedrosoi

Antifungal agents like itraconazole and terbinafine are commonly used. Surgery is often used to treat small, localized ... In Brazil, the agent has shown a 4:1 proclivity for men, likely as a function of exposure differences relating to work and ... The presence of the agent is associated with host cell proliferation and enlargement known as hyperplasia localized to the ... Topical application of amphotericin B followed by long-term administration of oral antifungal therapy has been shown to be ...

*Baldwin's rules

2007, 72, 6753-6757 doi:10.1021/jo0707939 Overhand, Mark; Hecht, Sidney M. (1994). "A Concise Synthesis of the Antifungal Agent ...

*Sirolimus

... was initially developed as an antifungal agent. However, this use was abandoned when it was discovered to have potent ... Rapamycin is used in biology research as an agent for chemically induced dimerization. In this application, rapamycin is added ... Vézina C, Kudelski A, Sehgal SN (October 1975). "Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the ... make it unlikely that this could become a widely used anti-aging agent. Among the strategies that have been explored to ...

*Ciclopirox

... olamine is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. It is most useful ... Ciclopirox is a considered a hydroxypyrimidine antifungal agent. In addition to other formulations, ciclopirox is used in ... Agents Chemother. 47 (6): 1805-17. doi:10.1128/AAC.47.6.1805-1817.2003. PMC 155814 . PMID 12760852. Ratnavel RC, Squire RA, ... Antimicrobial Agents and Chemotherapy. 47 (6): 1805-17. doi:10.1128/AAC.47.6.1805-1817.2003. PMC 155814 . PMID 12760852. Leem ...

*Protoanemonin

Martín, ML; San Román, L; Domínguez, A (1990). "In vitro activity of protoanemonin, an antifungal agent". Planta Medica. 56 (1 ...

*Isavuconazonium

... sulfate (BAL8557; trade name Cresemba) is a prodrug for isavuconazole which is a triazole antifungal agent. ... Miceli, MH; Kauffman, CA (15 November 2015). "Isavuconazole: A New Broad-Spectrum Triazole Antifungal Agent". Clinical ... synthesis and antifungal activity of a novel water soluble prodrug of antifungal triazole". Bioorganic & Medicinal Chemistry ... Guinea, J; Bouza, E (December 2008). "Isavuconazole: a new and promising antifungal triazole for the treatment of invasive ...

*Fungus

Loo DS (2006). "Systemic antifungal agents: an update of established and new therapies". Advances in Dermatology. 22: 101-24. ... and resistance to antifungal agents. One mechanism by which C. neoformans survives the hostile macrophage environment is by up- ... They have long been used as a direct source of human food, in the form of mushrooms and truffles; as a leavening agent for ... Certain species of the Pythium genus, which are oomycetes, have potential as biocontrol agents against certain fungi. Fungi can ...

*Candidiasis

Vaginal yeast infections are typically treated with topical antifungal agents. A one-time dose of fluconazole is 90% effective ... Agents Chemother. 48 (1): 161-7. doi:10.1128/AAC.48.1.161-167.2004. PMC 310176 . PMID 14693534. Morschhäuser J (Jul 18, 2002 ... In certain groups at very high risk, antifungal medications may be used preventatively. Infections of the mouth occur in about ... In vaginal yeast infection in pregnancy, treatment with topical azole antifungals is recommended for 7 days instead of a ...

*Malassezia

Gupta, A. K.; Nicol, K; Batra, R (2004). "Role of antifungal agents in the treatment of seborrheic dermatitis". American ... Shams-Ghahfarokhi M, Shokoohamiri MR, Amirrajab N, Moghadasi B, Ghajari A, Zeini F (2006). "In vitro antifungal activities of ... There are several natural antifungal remedies for seborrhoeic dermatitis including garlic, onions, coconut oil, apple cider ... A Major Causative Agent of Pityriasis Versicolor" (PDF). IJMS. 29 (1). Archived from the original (PDF) on 2012-04-25. Noble SL ...

*Epicoccum nigrum

It is a biocontrol antifungal agent active against brown rot in stone fruit, caused the species Monilinia laxa and Monilinia ... Flavipin, and epirodins A and B are pigmented antifungal agents; non-pigmented compounds include epicorazines A and B. ... Epicoccum nigrum produces a variety of biomedically and industrially useful metabolites, including important antifungal agents ... it is a widespread fungus which produces coloured pigments that can be used as antifungal agents against other pathogenic fungi ...

*Bohemic acid

Most of those components are antitumor agents and anthracycline antibiotics active against Gram-positive bacteria. Bohemic acid ... antifungal or antitumor activity. The bottom fragment of rudolphomycin is a cyclic (sugar) compound with a chemical formula ... Subscription or UK public library membership required.) "Antitumor agents from the bohemic acid complex. 4. Structures of ... "Antitumor Agents from Bohemic Acid Complex, VI. Schaunardimycin". Journal of Natural Products. 47 (4): 698-701. doi:10.1021/ ...