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*  Monoclonal antibody therapy
Chimeric and humanized antibodies have generally replaced them in therapeutic antibody applications. Understanding of ... Monoclonal antibody therapy is a form of immunotherapy that uses monoclonal antibodies (mAb) to bind monospecifically to ... Antigen 5T4 Immunotherapy Immunoconjugate Nomenclature of monoclonal antibodies List of monoclonal antibodies, including ... are therapeutic monoclonal antibodies. This rapid growth in demand for monoclonal antibody production has been well ...
*  Lebrikizumab
"anti-IL-13 humanized monoclonal antibody TNX-650". NCI Drug Dictionary. National Cancer Institute. Retrieved 10 December 2009. ... Lebrikizumab (INN) is a humanized monoclonal antibody and an experimental immunosuppressive drug for the treatment of asthma ...
*  Ixekizumab
Chemically, it is a humanized monoclonal antibody. The substance acts by blocking interleukin 17, reducing inflammation. The ... Ixekizumab is a complete monoclonal antibody of the subclass IgG4, consisting of two light chains and two heavy chains linked ... an interleukin-17A specific monoclonal antibody, for the treatment of biologic-naive patients with active psoriatic arthritis: ... The antibody has affinity to the homodimer IL-17A and the heterodimer IL-17A/F, but not to other members of the interleukin 17 ...
*  Drug nomenclature
Zumab is the suffix for humanized monoclonal antibody. Monoclonal antibodies by definition contain only a single antibody clone ... In the case of solanezumab, the antibody is designed to bond to the amyloid-β peptides which make up protein plaques on the ... "Antibody Production (Immunogen Preparation)". www.piercenet.com. Merriam-Webster, Merriam-Webster's Medical Dictionary, Merriam ...
*  Solar urticaria
Omalizumab is a recombinant humanized monoclonal antibody against IgE. It acts by binding free IgE at the same site that IgE ...
*  Motavizumab
... (proposed INN, trade name Numax) is a humanized monoclonal antibody. It is being investigated by MedImmune (today a ... when compared to the already available monoclonal antibody Palivizumab. In December 2010, AstraZeneca in a stock market ...
*  Rontalizumab
... is a humanized monoclonal antibody being developed by Genentech. As of November 2009[update], it is being ...
*  Biocon
T1h is a novel humanized monoclonal antibody that blocks CD6. In clinical trials in the autoimmune segment, T1h is the only ... Chronic plaque psoriasis: itolizumab, a humanized monoclonal antibody targeting the CD6 protein, became available to physicians ... Monoclonal Antibodies (MAbs): These are one of the fastest growing categories of the biopharmaceuticals industry with sales ... In 2006, Biocon launched BIOMAb EGFR the first indigenously developed humanised monoclonal antibody for head-and-neck cancer. ...
*  Samalizumab
... is a humanized monoclonal antibody designed for oncology indications. Samalizumab was developed by Alexion ...
*  Epratuzumab
... (planned trade name LymphoCide) is a humanized monoclonal antibody. Potential uses may be found in oncology and in ... Other SLE therapies destroy B-cells which compromises the immune system.) Epratuzumab, a humanized monoclonal antibody ... Humanized Anti-CD22 Monoclonal Antibody, Epratuzumab Clinical Cancer Research Vol. 11, July 15, 2005 free full text Epratuzumab ...
*  Otlertuzumab
... is a humanized monoclonal antibody designed for the treatment of cancer. This drug was developed by Emergent ...
*  Mevalonate kinase deficiency
tocilizumab (a humanized monoclonal antibody against the interleukin-6 (IL-6) receptor). This drug is used when the patients ... Examined in a 12-year-old patient). Canakinumab is a long acting monoclonal antibody which is directed against IL-1β has shown ... A beneficial effect of human monoclonal anti-TNFα antibody adalimumab was seen in a small number of MKD patients. Most MKD ...
*  Dalotuzumab
... is a humanized monoclonal antibody designed for the treatment of cancers. Dalotuzumab was developed by Merck & Co ...
*  Tadocizumab
... is a humanized monoclonal antibody that acts on the cardiovascular system. It binds to integrin αIIbβ3, a ...
*  Onartuzumab
... is a humanized monoclonal antibody designed for the treatment of cancer. Onartuzumab was developed by Genentech, ...
*  Apolizumab
... is a humanized monoclonal antibody intended for use in hematologic cancers. Development was abandoned in 2005, and ... "A humanized HLA-DR antibody (hu1D10, apolizumab) in combination with granulocyte colony-stimulating factor (filgrastim) for the ...
*  Ficlatuzumab
... is a humanized monoclonal antibody designed for the treatment of cancers. Ficlatuzumab was developed by AVEO ...
*  Sibrotuzumab
... is a humanized monoclonal antibody intended for the treatment of cancer. It binds to FAP In 2003 it failed a phase ... a novel therapeutic monoclonal antibody, in cancer patients". Investigational new drugs. 22 (1): 39-52. doi:10.1023/B:DRUG. ... "Stromal antigen targeting by a humanised monoclonal antibody: an early phase II trial of sibrotuzumab in patients with ...
*  Toralizumab
... was a humanized monoclonal antibody and an immunosuppressive drug. Possible indications included treatment of antibody-mediated ... A causal connection could not be proven, but since the same adverse effects were seen in trials with a similar antibody (hu5C8 ...
*  BGB-A317
... is a humanized monoclonal antibody directed against PD-1. It prevents PD-1 from binding to the ligands PD-L1 and PD-L2 ... Combined with PD-1 Antibody Tislelizumab (BGB-A317) ... Dec 2017 BeiGene Initiates Global Phase 3 Trial of Anti-PD-1 Antibody ... ASCO 2016 BeiGene (BGNE) Commences Pivotal Trial of PD-1 Antibody BGB-A317 in China in Patients with Urothelial Cancer. July ... Study Showing Anti-Cancer Activity in Range of Solid Tumors July 2016 Comparison of Efficacy and Safety of Anti-PD-1 Antibody ...
*  Pascolizumab
... is a humanized monoclonal antibody for the treatment of asthma. A Phase II clinical trial in patients with ... a humanized anti-interleukin-4 antibody with therapeutic potential in asthma". Clinical and experimental immunology. 130 (1): ...
*  Crotedumab
... (INN) is a humanized monoclonal antibody designed for the treatment of diabetes. This drug was developed by ...
*  Visilizumab
... (tentative trade name Nuvion, PDL BioPharma Inc.) is a humanized monoclonal antibody. It is being investigated for ... "Radiolabeled Humanized Anti-CD3 Monoclonal Antibody Visilizumab for Imaging Human T-Lymphocytes". Journal of Nuclear Medicine. ...
*  Tocilizumab
It is a humanized monoclonal antibody against the interleukin-6 receptor (IL-6R). Interleukin 6 (IL-6) is a cytokine that plays ... "Clinical improvement in a patient with neuromyelitis optica following therapy with the anti-IL-6 receptor monoclonal antibody ... 2007). "Anti-interleukin-6 receptor antibody (tocilizumab) treatment of multicentric Castleman's disease". Intern. Med. 46 (11 ...
*  Lumretuzumab
... (INN) is a humanized monoclonal antibody designed for the treatment of cancer. This drug was developed by ...
*  Rituximab
... antibody-dependent cellular cytotoxicity). This strategy for enhancing a monoclonal antibody's ability to induce ADCC takes ... humanized (90%-95% human) B cell-depleting agent. ofatumumab (HuMax-CD20) a fully human B cell-depleting agent. Third- ... Eccles, SA (2001). "Monoclonal antibodies targeting cancer: 'magic bullets' or just the trigger?". Breast cancer research : BCR ... Rituximab is a chimeric monoclonal antibody against the protein CD20, which is primarily found on the surface of immune system ...
*  Emibetuzumab
... (LY2875358) is a humanized monoclonal antibody designed for the treatment of cancer. It is in phase II trials for ...