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*  Autoantibody
The Antinuclear antibody (ANA) test is often ordered first. ANA is a marker of the autoimmune process - it is positive with a ... Antibodies are produced by B cells in two ways: (i) randomly, and (ii) in response to a foreign protein or substance within the ... An autoantibody is an antibody (a type of protein) produced by the immune system that is directed against one or more of the ... Initially, one B cell produces one specific kind of antibody. In either case, the B cell is allowed to proliferate or is killed ...
*  Systemic lupus erythematosus
Subtypes of antinuclear antibodies include anti-Smith and anti-double stranded DNA (dsDNA) antibodies (which are linked to SLE ... Antinuclear antibody (ANA) testing and anti-extractable nuclear antigen (anti-ENA) form the mainstay of serologic testing for ... These are most commonly anti-nuclear antibodies and they result in inflammation. Diagnosis can be difficult and is based on a ... These antibodies clump into antibody-protein complexes which stick to surfaces and damage blood vessels in critical areas of ...
*  Drug-induced lupus erythematosus
Antinuclear antibodies are usually positive in drug induced Lupus. Anti-Neutrophil Cytoplasmic antibodies (ANCA) can also be ... Furthermore, Anti-Histone antibodies can also be positive in drug induced lupus. Anti-Histone antibodies are positive in up to ... creating antinuclear antibodies leading to an immune response. Further studies on the interactions between oxidants and ... Anti-histone antibodies in 95% of cases These signs and symptoms are not side effects of the drugs taken which occur during ...
*  Anti-nuclear antibody
Anti-nuclear ribonucleoprotein (anti-nRNP) antibodies, also known as anti-U1-RNP antibodies, are found in 30-40% of SLE. They ... anti-Sm antibodies, anti-nRNP antibodies, anti-Scl-70 antibodies, anti-dsDNA antibodies, anti-histone antibodies, antibodies to ... Antinuclear antibodies (ANAs, also known as antinuclear factor or ANF) are autoantibodies that bind to contents of the cell ... This pattern is associated with anti-dsDNA antibodies, antibodies to nucleosomal components, and anti-histone antibodies. There ...
*  Anti-p62 antibodies
Invernizzi P, Selmi C, Ranftler C, Podda M, Wesierska-Gadek J (2005). "Antinuclear antibodies in primary biliary cirrhosis". ... 2003). "Profile and clinical significance of anti-nuclear envelope antibodies found in patients with primary biliary cirrhosis ... Anti-p62 antibodies (AP62A) are found in a primary biliary cirrhosis. The p62 protein is also more frequent in Stage IV primary ...
*  List of autoimmune diseases
Ehrenstein MR (August 1999). "Antinuclear antibodies and lupus: causes and consequences". Rheumatology. 38 (8): 691-3. doi: ... I. A clinical analysis of 55 anti-Yo antibody-positive patients". Neurology. 42 (10): 1931-7. doi:10.1212/wnl.42.10.1931. PMID ... Franceschini F, Cavazzana I (February 2005). "Anti-Ro/SSA and La/SSB antibodies". Autoimmunity. 38 (1): 55-63. doi:10.1080/ ... "Possible Source of Kawasaki Disease Found". Wisnieski JJ, Naff GB (September 1989). "Serum IgG antibodies to C1q in ...
*  Dermatomyositis
... especially antinuclear antibodies (ANA). Around 80% of people with DM test positive for ANA and around 30% of people have ... anti-synthetase antibodies), including antibodies against Histidine-tRNA ligase (also called Jo-1); antibodies to signal ... recognition particle (SRP); and anti-Mi-2 antibodies. Magnetic resonance imaging may be useful to guide muscle biopsy and to ... myositis-specific autoantibodies which include antibodies to aminoacyl-tRNA synthetases ( ...
*  Levamisole-induced vasculitis
... antinuclear antibodies were negative and p-ANCA was reactive. Coagulation studies were within normal limits. There was an ...
*  Scleromyositis
Blood testing includes screening for the positive antinuclear antibody. Patients have symptoms of both systemic scleroderma and ... Vandergheynst F, Ocmant A, Sordet C, Humbel RL, Goetz J, Roufosse F, Cogan E, Sibilia J (2006). "Anti-pm/scl antibodies in ... Autoantibodies often found in these patients are the anti-PM/Scl (anti-exosome) antibodies. The symptoms that are seen most ... There is still unanswered question of which antibodies will best treat connective tissue diseases. In some cases scleromyositis ...
*  Anti-Hu associated encephalitis
Graus F, Cordon-Cardo C, Posner JB (1985). "Neuronal antinuclear antibody in sensory neuronopathy from lung cancer". Neurology ... Nearly all people with the condition have anti-Hu antibodies in their serum. The antibody is produced by the body as an immune ... However, the injection of the antibodies into mice did not produce any disease, and the deposition of antibody was often not at ... Pohley I, Roesler K, Wittstock M, Bitsch A, Benecke R, Wolters A (2015). "NMDA-receptor antibody and anti-Hu antibody positive ...
*  Nuclear dots
Pawlotsky JM, Andre C, Metreau JM, Beaugrand M, Zafrani ES, Dhumeaux D (1992). "Multiple nuclear dots antinuclear antibodies ... They are also observed at higher frequencies in subacute sclerosing panencephalitis in these instances antibodies to measles ...
*  Immunoglobulin E
Permin H, Wiik A (1978). "The prevalence of IgE antinuclear antibodies in rheumatoid arthritis and systemic lupus erythematosus ... In the second approach, antibodies specific for a domain of 52 amino acid residues, referred to as CεmX or M1' (M1 prime), ... "Antibody structure". Archived from the original on September 6, 2008. Erb KJ (2007). "Helminths, allergic disorders and IgE- ... Immunoglobulin E (IgE) is a type of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. IgE is ...
*  HLA A1-B8-DR3-DQ2
Other genes in the region, C4A-null and TNF may associated with autoimmune hepatitis The appearance of anti-nuclear antibodies ... Christian N, Smikle MF, DeCeulaer K, Daniels L, Walravens MJ, Barton EN (March 2007). "Antinuclear antibodies and HLA class II ... of these half had anti-transglutaminase antibodies, but few had endomysial antibody. This could indicate an association with ... DR3 is found to correlate with anti-Ro/La antibodies in SLE. HLA-DR3 has been consistently observed at high frequencies in ...
*  Intermittent hydrarthrosis
Rheumatoid factor, cyclic citrullinated peptide antibodies and antinuclear antibodies are usually negative in IH. Palindromic ... 2007). "An unexpectedly high frequency of MEFV mutations in patients with anti-citrullinated protein antibody-negative ...
*  Anti-cardiolipin antibodies
"Antinuclear antibody, lupus anticoagulant, and anticardiolipin antibody in women with idiopathic habitual abortion. A ... They are a form of anti-mitochondrial antibody. In SLE, anti-DNA antibodies and anti-cardiolipin antibodies may be present ... Anti-cardiolipin antibodies (ACA) are antibodies often directed against cardiolipin and found in several diseases, including ... Only a subset of autoimmune anti-cardiolipin antibodies bind Apo-H, these anti-apolipoprotein antibodies are associated with ...
*  Robert Ira Lewy
Lewy, RI (1995). "Antinuclear Antibodies, Lipid Disturbances and Central Nervous System Imaging Abnormalities in Silicone ...
*  Caplan's syndrome
Rheumatoid factor, antinuclear antibodies, and non-organ specific antibodies may be present in the serum. Silicosis and ...
*  Rapidly progressive glomerulonephritis
The presence of anti-Glomerular basement membrane (GBM) antibodies suggests type I RPGN; antinuclear antibodies (ANA) may ... In addition to the anti-GBM antibodies, some cases of type I RPGN are also associated with antibodies directed against the ... The antibodies are directed against a particular protein found in the GBM, type IV collagen, specifically the noncollagenous ... The majority of type I disease, however, features anti-GBM antibodies alone; these cases are considered idiopathic. RPGN caused ...
*  Acute intermittent porphyria
Allard SA, Charles PJ, Herrick AL, McColl KE, Scott JT (1990). "Antinuclear antibodies and the diagnosis of systemic lupus ... Porphobilinogen Porphobilinogen deaminase Sodium Potassium Anti-nuclear antibody Creatinine Creatine kinase White blood cell ...
*  RA33
Hassfeld et al.: Demonstration of a new antinuclear antibody (anti-RA33) that is highly specific for rheumatoid arthritis. ... The pathogenic role of anti-RA33 antibodies is not fully understood. Anti-RA33 antibodies and T cells directed against RA33 ... However, anti-RA33 antibodies are not associated with significant bone erosions or disease activity. In the absence of ... Anti-RA33 antibodies can be easily detected by immunoblotting employing crude nuclear extracts or the recombinant antigen. ...
*  Neutrophil extracellular traps
NETs have also been associated with the production of IgG antinuclear double stranded DNA antibodies in children infected with ... "Cytokine-associated neutrophil extracellular traps and antinuclear antibodies in Plasmodium falciparum infected children under ... and complement receptors with various ligands such as antibodies, PMA, and so on. The current understanding is that upon ...
*  Anti-dsDNA antibodies
... are a group of anti-nuclear antibodies (ANA) the target antigen of which is double stranded DNA. Blood ... Animal tissue was the first substrate for immunofluorescent detection of antinuclear antibodies and has been in use since the ... The first evidence for antinuclear antibodies arose in 1948 when Hargraves, Richmond and Morton discovered the LE cell. These ... Kumar Y, Bhatia A, Minz RW (2009). "Antinuclear antibodies and their detection methods in diagnosis of connective tissue ...
*  Cell nucleus
Pattern of Antinuclear Antibody, and Complement-Fixing Antibodies to DNA in Sera from Patients with Systemic Lupus ... These are known as anti-nuclear antibodies (ANA) and have also been observed in concert with multiple sclerosis as part of ... S Barned; AD Goodman; DH Mattson (1995). "Frequency of anti-nuclear antibodies in multiple sclerosis". Neurology. 45 (2): 384- ... Antibodies to certain types of chromatin organization, in particular, nucleosomes, have been associated with a number of ...
*  Crithidia luciliae
... a type of anti-nuclear antibody. Anti-nuclear antibodies are a common feature in SLE and anti-dsDNA antibodies are highly ... "Guidelines for clinical use of the antinuclear antibody test and tests for specific autoantibodies to nuclear antigens. ... The kinetoplast found in C.luciliae allows them to be used for the detection of anti-dsDNA antibodies, ... the organelle can be used to detect anti-dsDNA antibodies, a common feature of the disease. C.luciliae is a eukaryotic single- ...
*  HLA A1-B8 haplotype
The association with viral hepatitis was subsequently demonstrated and patients with antinuclear antibodies were more likely to ... Though, the association of A1 with autoimmune hepatitis with no anti-viral antibody was stronger than with chronic active ...
*  Anti-Scl-70 antibodies
... is an anti-topoisomerase antibody-type of anti-nuclear autoantibodies, seen mainly in diffuse systemic scleroderma (with a ... Anti Scl-70 antibodies are associated with more severe scleroderma disease. The etymology of scl-70 consists of an abbreviation ... de Rooij DJ, Van de Putte LB, Habets WJ, Van Venrooij WJ (1989). "Marker antibodies in scleroderma and polymyositis: clinical ... of the antibodies. Guldner HH, Szostecki C, Vosberg HP, Lakomek HJ, Penner E, Bautz FA (1986). "Scl 70 autoantibodies from ...
*  Kikuchi disease
Antinuclear antibodies, antiphospholipid antibodies, anti-dsDNA, and rheumatoid factor are usually negative, and may help in ... Clinical findings sometimes may include positive results for IgM/IgG/IgA antibodies. For other causes of lymph node enlargement ... In addition, serologic tests including antibodies to a host of viruses have consistently proven noncontributory and no viral ...