... the FDA issued a boxed warning regarding the use of thyroid hormone stimulating agents in treatment of obesity. Data does not ... Meloxicam is a non-steroidal anti-inflammatory drug that is approved in the U.S. for a single post-operative injection in cats ... Hypothyroid agents should not be used in combination with sympathomimetic agents including: stimulants, and diet pills, due to ... FDA advisors have recommended that Pfizer be required to place a boxed warning on their non-steroidal anti-inflammatory drug ...
... anti-HBV, anti-cancer, anti-tuberculosis, anti-aging and anti-obesity. Three potential Category 1 drugs are also under ... Then, they appoint qualified agents to handle tenders. These agents are prohibited from having ties with the industry ... With adherence to the tenet of "healing for life", Zensun has long been focusing on the research of anti-tumor drugs and anti- ... the pharmacy enterprise search for its national or regional general agent and use the agent's market network to sell its ...
... findings suggest a possibility of the holothurins and other sea cucumber saponins being used in the development of anti-obesity ... Unlike the other mentioned blocking agents, the disrupting effect of holothurin appears to be quite irreversible upon washing. ... The holothurins are shown to have anti-melanogenic and anti-wrinkling effects on human skin by inhibiting melanin production in ... a factor which contributes to obesity, and stimulate the production of LXR-β nuclear receptor and ABCA1 protein. These ...
... functions as a cardio-protective peptide by being an anti-inflammatory agent, promoting angiogenesis, inhibiting ... Obesity, Peptide hormones, World Anti-Doping Agency prohibited substances). ... suggesting that ghrelin does not contribute to obesity, except in the cases of Prader-Willi syndrome-induced obesity, where ... It does not activate the GHS-R receptor but does have other effects: cardiac, anti-ghrelin, appetite stimulation, and ...
A mediterranean diet is often very effective due to its anti-inflammatory and anti-oxidative properties. Vitamin D deficiency ... Risk factors include obesity, a lack of physical exercise, and a family history of someone with the condition. Diagnosis is ... Although these agents have shown significant efficacy in clinical trials (for oral contraceptives, in 60-100% of individuals), ... Metformin and anti-androgens may also help. Other typical acne treatments and hair removal techniques may be used. Efforts to ...
... obesity, diabetes, cancer, immune responses, and may be a part of the mechanism of action of the widely-prescribed anti- ... cooperates with Galectin-8-based effects to inactivate mTOR downstream of the lysosomal damaging agents and conditions. The ... Mild lysosomal damage, such as that caused by the anti-diabetes drug metformin may contribute to the therapeutic action of ... "Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity" (PDF). The Journal of ...
IL1R1 knock-out mice exposed to celastrol exhibit no leptin-sensitizing or anti-obesity effect. In in vitro and in vivo animal ... August 2010). "Celastrol acts as a potent antimetastatic agent targeting beta1 integrin and inhibiting cell-extracellular ... It has been shown to have obesity-controlling effects in mice by inhibiting negative regulators of leptin. Celastrol has also ... Liu J, Lee J, Salazar Hernandez MA, Mazitschek R, Ozcan U (May 2015). "Treatment of obesity with celastrol". Cell. 161 (5): 999 ...
Gray, Emma "Disney's Anti-Obesity 'Habit Heroes' Exhibit At Epcot Causes Controversy (PHOTOS) [UPDATED]" Huffington Post. ... Director Jin and three agents, Agent Dynamo, representing physical activity, Agent Quench, representing hydration, and Agent ... "Disney World blunders with anti-obesity exhibit" Shine On, Yahoo Canada. Retrieved February 11th, 2013. Laucius, Joanne "How an ... Freedhoff, Yoni "Disney's Horrifying New Interactive Childhood Obesity Exhibit at Epcot" Weighty Matters. Retrieved February 11 ...
... an anti-obesity drug, and a remedy for severe depression. After those testing failures, Eli Lilly succeeded in treating five ... weight control agents, and antidepressants. In 1999, both Schmiegel and Molloy were inducted into the National Inventors Hall ...
... can be used as an anti-photoaging agent, as it prevents UVB-induced photoaging. Additionally, an experiment with ... This raises the possibility of the use against obesity related diseases and up to now incurable diseases. Cynaropicrin has a ... a comprehensive research review and therapeutic potential as an anti- hepatitis C virus agent". Frontiers in Pharmacology. 7: ... Cynaropicrin also shows anti-hyperlipidemic activity. The oxygen functional groups and the methylene of the GBL ring were found ...
Agents Used as Appetite Stimulants: Drug Class; University of Utah College of Pharmacy, 2014 Media related to Appetite ... Anorexia Eating disorder Obesity Organic feeding disorder Polydipsia Diepvens K, Häberer D, Westerterp-Plantenga M (Mar 2008 ... chlorpropamide and tolbutamide Mood stabilizers such as lithium Some anti-epileptic drugs such as valproate, carbamazepine and ... Hermansen K, Mortensen LS (2007). "Bodyweight changes associated with antihyperglycaemic agents in type 2 diabetes mellitus". ...
Esser N, Paquot N, Scheen AJ (March 2015). "Anti-inflammatory agents to treat or prevent type 2 diabetes, metabolic syndrome ... Powell K (May 2007). "Obesity: the two faces of fat". Nature. 447 (7144): 525-7. Bibcode:2007Natur.447..525P. doi:10.1038/ ... Salsalate is a medication that belongs to the salicylate and nonsteroidal anti-inflammatory drug (NSAID) classes. Salsalate is ... Ridker PM, Lüscher TF (July 2014). "Anti-inflammatory therapies for cardiovascular disease". European Heart Journal. 35 (27): ...
The first PPAR (PPARα) was discovered in 1990 during the search for a molecular target of a group of agents then referred to as ... In contrast, pro115gln is associated with obesity. Certain other polymorphisms in PPAR show a high incidence in populations ... For instance the hypolipidemic fibrates activate PPARα.[citation needed] The anti diabetic thiazolidinediones activate PPARγ.[ ... When it turned out that PPARs played a much more versatile role in biology, the agents were in turn termed PPAR ligands. The ...
For example, the anti-obesity drug orlistat causes a percentage of fat to pass through the digestive tract undigested. Amylase ... Ekholm P, Virkki L, Ylinen M, Johansson L (Feb 2003). "The effect of phytic acid and some natural chelating agents on the ... Like lipase inhibitors, they have been used as a diet aid and obesity treatment. They are present in many types of beans; ... Excessive intake of required nutrients can also result in them having an anti-nutrient action. Excessive intake of dietary ...
Coulter AA, Rebello CJ, Greenway FL (July 2018). "Centrally Acting Agents for Obesity: Past, Present, and Future". Drugs. 78 ( ... reversible anxiety and depression made it unsuitable for commercialization as an anti-obesity drug, and its development was ... One such behavior is eating, and ecopipam has been shown in a large clinical study to be an effective treatment for obesity. ... The drug was also under development for the treatment of cocaine-related disorders, obesity, and schizophrenia, but development ...
However, once the potential anti-obesity effects of METAP2 inhibition became apparent, the clinical development began to focus ... Kim EJ, Shin WH (February 2005). "General pharmacology of CKD-732, a new anticancer agent: effects on central nervous, ... a novel obesity treatment for safety, tolerability, and weight loss in obese women". Obesity. 21 (9): 1782-8. doi:10.1002/oby. ... Beloranib is a former drug candidate for the treatment of obesity. It was discovered by CKD Pharmaceuticals and its clinical ...
... as anti-obesity drugs. The primary forebrain sensor of peripheral cues that relays information about the availability of energy ... began a collaboration to search for potential antidepressant agents that would still retain the therapeutic activity of TCAs ... It has been used to research obesity and energy balance, and exerts some local analgesia effects. Researchers have attempted to ... Bray GA, Greenway FL (December 1999). "Current and potential drugs for treatment of obesity". Endocrine Reviews. 20 (6): 805-75 ...
Hong L, Xun M, Wutong W (April 2007). "Anti-diabetic effect of an alpha-glucan from fruit body of maitake (Grifola frondosa) on ... Alternative Agents in Type 1 Diabetes in Addition to Insulin Therapy: Metformin, Alpha-Glucosidase Inhibitors, Pioglitazone, ... Obesity & Metabolism. 4 (1): 43-48. doi:10.1046/j.1463-1326.2002.00180.x. PMID 11874441. S2CID 23788507. Horio H, Ohtsuru M ( ... Kubo K, Aoki H, Nanba H (August 1994). "Anti-diabetic activity present in the fruit body of Grifola frondosa (Maitake). I". ...
ISBN 978-0-12-518121-1. Holmes, J. H.; Sapeika, N; Zwarenstein, H (1975). "Inhibitory effect of anti-obesity drugs on NADH ... and as anti-malaria agents (atovaquone). Also propylhexedrine inhibits cytochrome c reductase. A small fraction of electrons ...
His early studies demonstrated that the immunomodulatory agent β-glucan enhances anti-tumor therapeutic efficacy when combined ... obesity, cancer development, and their influence on immune cell functions relevant to obesity-related diseases. In 2020, he ... Li has been appointed as the Director of Iowa Cancer and Obesity Initiative at the University of Iowa and serves as a Steering ... His research indicates FABP4, also known as adipose FABP(A-FABP), as a new player linking obesity-increased risk of breast ...
Osteoarthritis and obesity are closely linked. Obesity is one of the most important preventable factors for the development of ... Potential side effects are weight loss and the development of anti-metreleptin antibodies. The leptine was discovered by ... There are nutritional supplements and pharmacological agents capable of directing these factors and improving both conditions.[ ... February 2006). "G-2548A polymorphism of the leptin gene is correlated with extreme obesity in Taiwanese aborigines". Obesity. ...
For example, IL-2 signaling in T cells upregulates the expression of anti-apoptotic protein Bcl-2, but T cell production of IL- ... This is one of the causes of a low-grade systemic chronic inflammatory state associated with obesity. Though very similar in ... Once engulfed by a macrophage, the causative agent of tuberculosis, Mycobacterium tuberculosis, avoids cellular defenses and ... Obesity is associated with macrophage accumulation in adipose tissue" Journal of Clinical Investigation 2003; 112:1796-808. ...
His studies have revealed adiponectin's potent anti-diabetes effects of blocking glucose production in the liver and improving ... Beutler was honored for the discovery of receptor proteins that recognize disease-causing agents and activate innate immunity ... Postdoctoral certificates are offered in Research, Advanced Research, Cancer, Educational Techniques, Obesity and Metabolism, ... Diabetes/Obesity (Philipp Scherer's discovery of adiponectin, a hormone produced by fat, has helped transform the scientific ...
... anti-obesity campaign. In March 2011, Barbour drew criticism for his role in allowing the release of a convicted killer eight ... Insurance agent Guy E. "Butch" Evans paid $100,000. The evacuation order for Hurricane Katrina was issued by local officials ...
Keller WR, Kum LM, Wehring HJ, Koola MM, Buchanan RW, Kelly DL (April 2013). "A review of anti-inflammatory agents for symptoms ... Obesity & Metabolism. 14 (4): 329-34. doi:10.1111/j.1463-1326.2011.01529.x. PMID 22059694. S2CID 28553141. Singh SP, Singh V ( ... Sommer IE, van Westrhenen R, Begemann MJ, de Witte LD, Leucht S, Kahn RS (January 2014). "Efficacy of anti-inflammatory agents ... Anti-inflammatories, anti-depressants, and mood stabilisers are other add-ons used. Other strategies used include ECT, or ...
... acts as a releasing agent of norepinephrine and dopamine with EC50 values of 50.4 ± 5.4 nM and 131 ± 11 nM, ... ISBN 0-85369-473-7. Engelhardt A (1961). "Studies of the Mechanism of the Anti-Appetite Action of Phenmetrazine". Biochem. ... Hampson J, Loraine JA, Strong JA (June 1960). "Phenmetrazine and dexamphetamine in the management of obesity". Lancet. 1 (7137 ... Martel A (January 1957). "Preludin (phenmetrazine) in the treatment of obesity". Canadian Medical Association Journal. 76 (2): ...
One of the commonly used medications for atopic eczema is non-prescription cream containing an anti-inflammatory agent 1% ... obesity, hyperlipidemia, hypertension, cardiovascular diseases, autoimmunity, and asthma. Therapeutic use of breastmilk has ... Lactoferrin has multiple actions including lymph-stimulatory, anti-inflammatory, anti-bacterial, anti-viral, and anti-fungal ... Breastfeeding has an anti-inflammatory effect that is conveyed by its chemical components' interaction with body cells. The ...
Synthetic LXR agonist GW3965 improves glucose tolerance in a murine model of diet-induced obesity and insulin resistance by ... as liver X receptor ligands and antibacterial agents". J. Nat. Prod. 68 (9): 1437-40. doi:10.1021/np050176k. PMID 16180833. ... LXR agonists are effective for treatment of murine models of atherosclerosis, diabetes, anti-inflammation, Alzheimer's disease ... indicating that T0901317 and GW3965 may not be a good candidate for a therapeutic agent. LXR agonists (T0901317, 22(R)- ...
... nonsteroidal anti-inflammatory drugs (NSAIDs), glyburide, insulin, anxiolytic agents, adrenergic agonists, and cholinergic ... Olfactory Associated with systemic medical problems Parkinson's disease Fibromyalgia Congestive heart failure Anxiety Obesity ... Topical agents for hyperhidrosis therapy include formaldehyde lotion, topical anticholinergics etc. These agents reduce ... which cannot be managed by topical agents.[when?] A microwave-based device has been tried for excessive underarm perspiration ...
... other anti-depressants, anti-convulsants, analgesics, antiemetic agents, anti-migraine medications, methylene blue, linezolid, ... Luque CA, Rey JA (April 2002). "The discovery and status of sibutramine as an anti-obesity drug". European Journal of ... Selectivity of antidepressant agents are based on the neurotransmitters that are thought to influence symptoms of depression. ... Agents with dual serotonin and norepinephrine reuptake inhibition (SNRIs) are sometimes called non-tricyclic serotonin and ...
... is increasingly expressed with obesity and aging, resulting in reduced levels of the anti-inflammatory, pro-autophagy, ... "Role of RCP006 as an anti-inflammatory agent". Roskamp Institute. Archived from the original on 2011-10-23. Retrieved 2011-09- ... Many natural products (including anti-oxidants) that have been promoted to have anti-cancer and anti-inflammatory activity have ... or to become more sensitive to the action of anti-tumor agents. Thus, NF-κB is the subject of much active research among ...