Anti-Infective Agents in Medicinal Chemistry. 6 (1): 49-56. doi:10.2174/187152107779314179. Archived (PDF) from the original on ... Quinolones exert their antibacterial effect by preventing bacterial DNA from unwinding and duplicating.[60] Specifically they ... Anti-Infective Agents in Medicinal Chemistry. 6 (1): 49-56. doi:10.2174/187152107779314179.. ... Quinolones can be classified into generations based on their antibacterial spectrum.[81][82] The earlier-generation agents are ...
Anti-Infective Agents in Medicinal Chemistry. Bentham Science Publishers. 6 (1): 49-56. doi:10.2174/187152107779314179.. ... Quinolones exert their antibacterial effect by preventing bacterial DNA from unwinding and duplicating.[59] The majority of ... Anti-Infective Agents in Medicinal Chemistry. Bentham Science Publishers. 6 (1): 49-56. doi:10.2174/187152107779314179. ... Quinolones can be classified into generations based on their antibacterial spectrum.[79][80] The earlier-generation agents are ...
... need DHFR to grow and multiply and hence inhibitors selective for bacterial DHFR have found application as antibacterial agents ... Regardless, trimethoprim and sulfamethoxazole in combination has been used as an antibacterial agent for decades.[37] ... Trimethoprim, an antibiotic, inhibits bacterial DHFR while methotrexate, a chemotherapy agent, inhibits mammalian DHFR. However ... Hawser S, Lociuro S, Islam K (March 2006). "Dihydrofolate reductase inhibitors as antibacterial agents". Biochemical ...
Lysobactin, a novel antibacterial agent produced by Lysobacter sp. II. Biological properties. J Antibiot (Tokyo) 41:1745-51. ... Bean rust biological control using bacterial agents. Crop Protection 20:395-402. Jochum, C. C., L. E. Osborne, and G. Y. Yuen. ... Lysobactin, a novel antibacterial agent produced by Lysobacter sp. I. Taxonomy, isolation and partial characterization. J ... A new anti-MRSA antibiotic complex, WAP-8294A. I. Taxonomy, isolation and biological activities. J Antibiot (Tokyo) 51:929-35. ...
Antibacterial therapeutic agents". Feigin & Cherry's textbook of pediatric infectious diseases (6th ed.). Philadelphia, PA: ... Need for the determination of chloramphenicol levels in the treatment of bacterial-purulent meningitis with chloramphenicol ... Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents". Goodman & Gilman's The Pharmacological Basis of ... Two pathophysiologic mechanisms are thought to play a role in the development of gray baby syndrome after exposure to the anti- ...
Examples include anti-allergic, anti-inflammatory, antioxidant, anti-microbial (antibacterial, antifungal, and antiviral), anti ... Cushnie TP, Lamb AJ (2005). "Antimicrobial activity of flavonoids" (PDF). International Journal of Antimicrobial Agents. 26 (5 ... the ability to suppress bacterial virulence factors in numerous in vitro and a limited number of in vivo studies. Noteworthy ... Babu PV, Liu D, Gilbert ER (2013). "Recent advances in understanding the anti-diabetic actions of dietary flavonoids". The ...
"Targeting antibacterial agents by using drug-carrying filamentous bacteriophages". Antimicrob. Agents Chemother. 50 (6): 2087- ... The high bacterial strain specificity of phage therapy may make it necessary for clinics to make different cocktails for ... Purified recombinant phage enzymes can be used as separate antibacterial agents in their own right. The simplest method of ... Shasha SM, Sharon N, Inbar M (2004). "[Bacteriophages as antibacterial agents]". Harefuah (in Hebrew). 143 (2): 121-5, 166. ...
In the inter-war period, the first anti-bacterial agents such as the sulpha antibiotics were developed. The Second World War ... These were drugs that worked chiefly as anti-anxiety agents and muscle relaxants. The first benzodiazepine was Librium. Three ... Anti-allergy: mast cell inhibitors. *Anti-glaucoma: adrenergic agonists, beta-blockers, carbonic anhydrase inhibitors/ ... of new data on the development of novel antibiotics and antibacterials and on the use of biological agents for antibacterial ...
Infectious complications: an appropriate course of antibacterial drugs can be taken according to the infectious agent. ... Spontaneous bacterial peritonitis can develop where there is ascites present. This is a frequent development in children but ... Proteinuria: the loss of proteins from the urine is caused by many pathological agents and infection by these agents has to be ... Treatment is with oral anticoagulants (not heparin as heparin acts via anti-thrombin 3 which is lost in the proteinuria so it ...
These drugs are anti-cancer therapies. bacterial type II topoisomerase inhibitors (gyrase and topo IV): fluoroquinolones. These ... Topoisomerase inhibitors can also function as antibacterial agents. Quinolones (including nalidixic acid and ciprofloxacin) ... more effective as anti-tumor agents in animal models. The preclinical and IND package filed with the US Food and Drug ... Quinolone and Pyridone Antibacterial Agents". Chemical Reviews. 105 (2): 559-92. doi:10.1021/cr030101q. PMID 15700957. Fisher, ...
"Pharmacokinetics and pharmacodynamics of antibacterial agents". Infectious Disease Clinics of North America. 23 (4): 791-815, ... "Morphological and ultrastructural changes in bacterial cells as an indicator of antibacterial mechanism of action". Cellular ... The uricosuric agent probenecid proved to be suitable. When probenecid and penicillin are administered together, probenecid ... β-Lactam antibiotics inhibit the formation of peptidoglycan cross-links in the bacterial cell wall; this is achieved through ...
Mahajan, GB (2012). "Antibacterial agents from actinomycetes - a review". Frontiers in Bioscience. 4: 240-53. doi:10.2741/e373. ... Actinobacteria is one of the dominant bacterial phyla and contains one of the largest of bacterial genera, Streptomyces.[3] ... Pandey, B.; Ghimire, P.; Agrawal, V.P. (January 12-15, 2004). Studies on the antibacterial activity of the Actinomycetes ... Although some of the largest and most complex bacterial cells belong to the Actinobacteria, the group of marine Actinomarinales ...
Hiraki, J. (1995). "Basic and applied studies on ε-polylysine". Journal of Antibacterial Antifungal Agents. 23: 349-354. Mazia ... This eventually leads to the abnormal distribution of the cytoplasm causing damage to the bacterial cell that is produced by ... which offers a new way to deliver therapeutic agents specifically to the sites of injury after vascular damage. In 2010, ... which can be used either as surfactants or emulsifiers in the encapsulation of water-insoluble drugs or as antimicrobial agents ...
Agents with anti-pseudomonal activity, including doripenem, imipenem, and meropenem are not recommended in this population. ... Antimicrobial resistance NDM-1 is an enzyme that introduces bacterial resistance to carbapenem antibiotics via hydrolysis of ... Structure Activity Relationships "Antibacterial Agents; Structure Activity Relationships," André Bryskier MD; beginning at ... Agents Chemother. 55 (11): 4943-60. doi:10.1128/AAC.00296-11. PMC 3195018 . PMID 21859938. Livermore DM, Woodford N (October ...
ISBN 0-12-526451-8. Structure Activity Relationships "Antibacterial Agents; Structure Activity Relationships", André Bryskier ... The primary means of bacterial resistance to macrolides occurs by post-transcriptional methylation of the 23S bacterial ... Macrolide antibiotics do so by binding reversibly to the P site on the 50S subunit of the bacterial ribosome. This action is ... Classification of agents[permanent dead link] Pharmamotion. Author: Gary Kaiser. The Community College of Baltimore County. ...
Mechanism of Action of Antibacterial Agents. Berlin, Heidelberg: Springer Berlin Heidelberg. ISBN 3-642-46403-3. CS1 maint: ... the Bacterial Diversity Metadatabase. ...
Gardnerella at the US National Library of Medicine Medical Subject Headings (MeSH) Mahajan, GB (2012). "Antibacterial agents ... Actinobacteria is one of the dominant bacterial phyla and contains one of the largest of bacterial genera, Streptomyces. ... Although some of the largest and most complex bacterial cells belong to the Actinobacteria, the group of marine Actinomarinales ... Pandey, B.; Ghimire, P.; Agrawal, V.P. (January 12-15, 2004). Studies on the antibacterial activity of the Actinomycetes ...
host DHFR have found application as antibacterial agents. Classes of small-molecules employed as inhibitors of dihydrofolate ... Bacteria also need DHFR to grow and multiply and hence inhibitors selective for bacterial vs. ... Hawser S, Lociuro S, Islam K (March 2006). "Dihydrofolate reductase inhibitors as antibacterial agents". Biochemical ... A variety of drugs act as inhibitors of dihydrofolate reductase: the experimental antimalarial and anti-toxoplasmosis compound ...
"New Family Of Antibacterial Agents Uncovered". Science News. ScienceDaily. 2009-01-17. Retrieved 2009-01-17. Jung S, Dingley AJ ... Functionally, the protein causes bacterial cells to clump together and aggregate, changing the morphology of the bacterial ... This potent antibacterial activity extended to known multi-resistant strains of pathogenic bacteria, such as those of ... This results in a disruption of the structure of the bacterial membrane. Hydramacin-1 was first isolated from epithelial cells ...
Quinolones exert their antibacterial effect by preventing bacterial DNA from unwinding and duplicating. The majority of ... Quinolones can be classified into generations based on their antibacterial spectrum. The earlier-generation agents are, in ... Risks of antibacterial agents in pregnancy]". Le Infezioni in Medicina. 10 (1): 8-15. PMID 12700435. Bar-Oz B, Moretti ME, ... Anti-Infective Agents in Medicinal Chemistry. Bentham Science Publishers. 6 (1): 49-56. doi:10.2174/187152107779314179. Chang Y ...
"Risks of antibacterial agents in pregnancy". Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, ... In the U.S. ofloxacin is approved for the treatment of bacterial infections such as: Acute bacterial exacerbations of chronic ... An eye drop may be used for a superficial bacterial infection of the eye and an ear drop may be used for otitis media when ... Agents Chemother. 22 (4): 548-53. doi:10.1128/aac.22.4.548. PMC 183791 . PMID 6960805. Retrieved 2014-09-28. Owens RC, Ambrose ...
Mechanism of Action of Antibacterial Agents. Berlin, Heidelberg: Springer Berlin Heidelberg. ISBN 3-642-46403-3. CS1 maint: ... ISBN 0-412-25790-4. Type strain of Streptomyces rishiriensis at BacDive - the Bacterial Diversity Metadatabase. ... Cragg, edited by Gordon M.; Kingston,, David G.I.; Newman, David J. (2012). Anticancer agents from natural products (2nd ed.). ... Cragg, edited by Gordon M.; Kingston,, David G.I.; Newman, David J. (2012). Anticancer agents from natural products (2nd ed.). ...
"Long-circulating bacteriophage as antibacterial agents". Proceedings of the National Academy of Sciences. 93 (8): 3188-3192. ... He is best known for his work on bacterial transcription and the biology of bacteriophage lambda. He has made important ... the organization of the bacterial nucleoid, and phage therapy. Dr. Adhya was born in Kolkata, India and studied chemistry at ...
A number of wound dressings containing silver as an anti-bacterial have been cleared by the U.S. Food and Drug Administration ( ... "Antimicrobial Agents and Chemotherapy. 6 (5): 637-642. doi:10.1128/AAC.6.5.637. PMC 444706 . PMID 15825319.. ... likely due to the release of silver into the bacterial culture.[52] The antibacterial action of electrodes coated with silver ... Antibacterial cream[edit]. See also: Silver sulfadiazine. A 2012 systematic review reported that topical silver showed a ...
Zhanel, G.G (10 February 2016). "Review of Eravacycline, a Novel Fluorocycline Antibacterial Agent". Drugs. 76 (5): 567-588. ... the first tetracycline-resistant bacterial pathogen was identified. Since then, tetracycline-resistant bacterial pathogens have ... "Antimicrobial Agents and Chemotherapy. 7 (1): 46-49. doi:10.1128/aac.7.1.46. ISSN 0066-4804. PMC 429070. PMID 1137358.. ... "Antimicrobial Agents and Chemotherapy. 60 (8): 4433-4441. doi:10.1128/AAC.00594-16. PMC 4958212. PMID 27246781.. ...
Competence in S. pneumoniae is induced by DNA-damaging agents such as mitomycin C, fluoroquinolone antibiotics (norfloxacin, ... Invasins, such as pneumolysin, an antiphagocytic capsule, various adhesins, and immunogenic cell wall components are all major ... Natural bacterial transformation involves the transfer of DNA from one bacterium to another through the surrounding medium. ... van de Beek, Diederik; de Gans, Jan; Tunkel, Allan R.; Wijdicks, Eelco F.M. (5 January 2006). "Community-Acquired Bacterial ...