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*  Management of atrial fibrillation
The agents work by prolonging the Effective Refractory Period (ERP) either by blocking sodium ions (Class I drugs) or by ... The anti-arrhythmic medications often used in either pharmacological cardioversion or in the prevention of relapse to AF alter ... as it is the only reliably effective method for relieving the symptoms of the arrhythmia and can be used when other methods ... Among patients with nonvalvular AF, anticoagulation with warfarin can reduce stroke by 60% while antiplatelet agents can reduce ...
*  Nadoxolol
Warembourg H, Ducloux G. [Clinical study of a new anti-arrhythmia agent: nadoxolol]. Lille Med. 1976;21(4 Suppl 2):386-8. PMID ... Nadoxolol is an antiarrhythmic agent, chemically related in structure to beta-adrenergic receptor blocker drugs such as ...
*  Cymarin
... is a cardiac glycoside and an anti-arrhythmia and cardiotonic agent. Edible and Medicinal plants of the West, Gregory L ...
*  Effective refractory period
Anti-arrhythmic agents used for arrhythmias usually prolong the ERP. For the treatment of atrial fibrillation, it is a problem ... that the prolongation of the ERP by these agents also affects the ventricles, which can induce other types of arrhythmias.. ... ERP acts as a protective mechanism and keeps the heart rate in check and prevents arrhythmias, and it helps coordinates muscle ...
*  Procainamide
... works as an anti-arrhythmic agent and is used to treat cardiac arrhythmia. It induces rapid block of the ... Procainamide is used for treating ventricular arrhythmias: ventricular ectopy and tachycardia and supraventricular arrhythmias ... Procainamide is a medication of the antiarrhythmic class used for the treatment of cardiac arrhythmias. It is classified by the ... It was found that procainamide was effective for treating ventricular arrhythmias, but it had the same toxicity profile as ...
*  Pharmacognosy
... the spasmolysis agent atropine; the vasodilator vincamine; the anti-arhythmia compound quinidine; the anti-asthma therapeutic ... Most bioactive compounds of natural origin are secondary metabolites, i.e., species-specific chemical agents that can be ... Balick, MJ (1990). "Ethnobotany and the identification of therapeutic agents from the rainforest". In Anonymous. Bioactive ... grouped into various categories.[citation needed] A typical protocol to isolate a pure chemical agent from natural origin is ...
*  List of MeSH codes (D16)
... uricosuric agents MeSH D27.505.954.411 --- cardiovascular agents MeSH D27.505.954.411.097 --- anti-arrhythmia agents MeSH ... anti-allergic agents MeSH D27.505.954.122 --- anti-infective agents MeSH D27.505.954.122.085 --- anti-bacterial agents MeSH ... antiviral agents MeSH D27.505.954.122.388.077 --- anti-retroviral agents MeSH D27.505.954.122.388.077.088 --- anti-hiv agents ... renal agents MeSH D27.505.954.613.056 --- anti-infective agents, urinary MeSH D27.505.954.613.860 --- uricosuric agents MeSH ...
*  HBI-3000
... the intravenous injection of HBI-3000 demonstrated to be an effective anti-arrhythmic and anti-fribrillatory agent. The ... Clinical investigation will test the safety and efficacy of HBI-3000 as a treatment for both atrial and ventricular arrhythmias ... Anti-arrhythmic medication is taken to treat irregular beating of the heart. This irregular beating results from a deregulation ... Most anti-arrhythmic medications exert their effects by decreasing the permeability of potassium ion channels (IKr) in heart ...
*  AZD1305
Available anti-arrhythmic agents (AAD) used for the maintenance of AF are often accompanied with the risk of developing ... AZD1305 is an experimental drug candidate that is under investigation for the management and reversal of cardiac arrhythmias, ... The combined block of INa, IKr, and L-type calcium current is key to the anti-arrhythmic potential of AZD1305 compared IKr ... AZD1305 possesses class III anti-arrhythmic activity by blocking the human ether-a-go-go-related gene (hERG) potassium channel ...
*  Hyoscyamine
When hyoscyamine is used along with opioids or other anti-peristaltic agents, measures to prevent constipation are especially ... Side effects include dry mouth and throat, eye pain, blurred vision, restlessness, dizziness, arrhythmia, flushing, and ...
*  Celivarone
... a drug commonly used to treat arrhythmias. Celivarone has potential as an antiarrhythmic agent, attributable to its ... "In vivo and in vitro Characterization of the Novel Antiarrhythmic Agent SSR149744C: Electrophysiological, Anti-adrenergic, and ... Cardiac arrhythmia is any abnormality in the electrical activity of the heart. Arrhythmias range from mild to severe, sometimes ... Since it affects multiple ion channels, it also shows promise in treating genetic forms of arrhythmia caused by several ion ...
*  Magnesium (medical use)
... sulfate is the first-line agent for such use under the 2005 ECC guidelines and for managing quinidine-induced arrhythmias. As a ... Anti-contraction medication: Magnesium sulfate can also delay labor in the case of premature labor, to delay preterm birth. ... In very severe cases, it can cause coma, cardiac arrhythmia, cardiac arrest and death. Magnesium overdose can be counteracted ... Laxative use, particularly magnesium citrate and magnesium hydroxide Antiarrhythmic agent for torsades de pointes in cardiac ...
*  Oleandrin
... is a promising agent for anti-cancer treatment. Studies show potential in vitro effect for cancers of the colon, non- ... Patients receiving an adequate dose of anti-digoxin Fab show a good response, resolving serious arrhythmias in two hours in ... The use of anti-digoxin Fab IV has proven successful in cases of oleandrin poisoning These antibodies have shown to bind in ... The reason anti-digoxin Fab is sparingly used in developing countries is its high cost, even though it is such an effective ...
*  Outline of cardiology
Cardiac arrhythmias - conditions in which the heartbeat is irregular, too fast, or too slow. Many types of arrhythmia have no ... Perhaps the most prominent manipulation of ion channels is through antiarrhythmic agents. These agents are commonly classified ... SSRI's also have interactions with anti-coagulation therapy and increases the risk of bleeding while on them. Serotonin- ... A common arrhythmia that can lead to this form of cardiomyopathy is the common atrial fibrillation. Takotsubo cardiomyopathy ( ...
*  Tedisamil
Atrial arrhythmias are the most common type of arrhythmia with several subtypes currently described, including atrial ... 2000). "Antianginal and anti-ischemic efficacy of tedisamil, a potassium channel blocker". Heart. 83: 167-171. doi:10.1136/ ... is an experimental class III antiarrhythmic agent currently being investigated for the treatment of atrial fibrillation. ... Arrhythmias are broadly defined as abnormal electrical activity in the heart and can affect both the atria and ventricles. ...
*  Azimilide
Although each agent has its own properties and will have thus a different function. Azimilide dihydrochloride is a ... Most recent clinical trials have investigated the use of azimilide in reducing the frequency and severity of arrhythmias in ... Azimilide has been studied for its anti-arrhythmic effects: its converts and maintains sinus rhythm in patients with atrial ... Azimilide is a class ΙΙΙ antiarrhythmic drug (used to control abnormal heart rhythms). The agents from this heterogeneous group ...
*  Supraventricular tachycardia
A variety of drugs including simple AV nodal blocking agents such as beta-blockers and verapamil, as well as anti-arrhythmics ... "How Are Arrhythmias Diagnosed?". NHLBI. July 1, 2011. Archived from the original on February 18, 2015. "How Are Arrhythmias ... "Types of Arrhythmia". NHLBI. July 1, 2011. Archived from the original on June 7, 2015. Al-Zaiti, SS; Magdic, KS (September 2016 ... Once an acute arrhythmia has been terminated, ongoing treatment may be indicated to prevent recurrence. However, those that ...
*  Acecainide
It is a Class III antiarrhythmic agent, whereas procainamide is a Class Ia antiarrhythmic drug. It is only partially as active ... During and after his surgery he was facing problems with arrhythmias. These problems were investigated by Frederick R. Mautz. ... Measuring the ratio of acecainide and procainamide concentrations together helps to achieve an optimum anti-arrhythmic effect ... In patients who are refractory to other antiarrhythmic agents, the doses required appear to be greater. Moreover, a few studies ...
*  Antiarrhythmic agent
Class II agents are anti-sympathetic nervous system agents. Most agents in this class are beta blockers. Class III agents ... Action potential Cardiac action potential Cardiac Arrhythmia Suppression Trial (CAST) Electrocardiogram Proarrhythmic agent ... Class IV agents affect calcium channels and the AV node. Class V agents work by other or unknown mechanisms. With regards to ... Class I agents are called membrane-stabilizing agents. The 'stabilizing' word is used to describe the decrease of ...
*  Bepridil
It has been implicated in causing ventricular arrhythmia (torsades de pointes). In June 2015 a research paper was published ... "A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity". "Zoloft as Ebola cure ... May 2008). "Use of bepridil in combination with Ic antiarrhythmic agent in converting persistent atrial fibrillation to sinus ...
*  Paroxysmal supraventricular tachycardia
SVT that does not involve the AV node may respond to other anti-arrhythmic drugs such as sotalol or amiodarone. If the person ... "Types of Arrhythmia". NHLBI. July 1, 2011. Archived from the original on June 7, 2015. "BestBets: Comparing Valsalva manoeuvre ... an ultra-short-acting AV nodal blocking agent, is indicated if vagal maneuvers are not effective. If unsuccessful or the PSVT ... "What Are the Signs and Symptoms of an Arrhythmia?". NHLBI. July 1, 2011. Archived from the original on 19 February 2015. ...
*  Pharmacotoxicology
Anti-depressants have been prescribed since the 1950s, and their prevalence has significantly increased since then. There are ... Doxorubicin is an uncoupling agent in that it inhibits proper functioning of complex I of the electron transport chain in ... but have high incidences of cardiac arrhythmias and myocardial infarctions. Guengerich, F. Peter (2011). "Mechanisms of Drug ... Other anti-cancer drugs, such as fluoropyrimidines and taxanes, are extremely effective at treating and reducing tumor ...
*  Amiodarone
It is used both in supraventricular arrhythmias and ventricular arrhythmias. Defibrillation is the treatment of choice for ... Amiodarone also causes an anti-thyroid action, via Wolff-Chaikoff effect, due its large amount of iodine in its molecule, which ... Common practice is to avoid the agent if possible in individuals with decreased lung function. The most specific test of ... In 1974 it was found to be useful for arrhythmias and reintroduced. It is on the World Health Organization's List of Essential ...
*  5-HT3 antagonist
Galanolactone, a diterpenoid found in ginger, is a 5-HT3 antagonist and is believed to at least partially mediate the anti- ... Pasricha, Pankaj J. (2006). "Treatment of Disorders of Bowel Motility and Water Flux; Antiemetics; Agents Used in Biliary and ... such as prolongation of the PT and QTc intervals and certain arrhythmias. The clinical significance of these side effects is ... 1991). "Anti-5-hydroxytryptamine3 effect of galanolactone, diterpenoid isolated from ginger". Chem Pharm Bull. 39 (2): 397-9. ...
*  HERG
... anti-psychotic agents, and certain antibiotics (including quinolones and macrolides). Although there exist other potential ... Sanguinetti MC, Tristani-Firouzi M (March 2006). "hERG potassium channels and cardiac arrhythmia". Nature. 440 (7083): 463-9. ... Sanguinetti MC, Tristani-Firouzi M (2006). "hERG potassium channels and cardiac arrhythmia". Nature. 440 (7083): 463-9. doi: ... that can lead to the risk of potentially fatal cardiac arrhythmias (e.g., torsades de pointes), due to repolarization ...
*  Doxepin
Antiarrhythmic agents may be an appropriate measure to treat cardiac arrhythmias resulting from doxepin overdose. Slow ... PMC 4027305 . In general, sedating properties of anti-depressant agents are related to antagonism of serotonin 5HT2, histamines ... Sympathomimetic agents may have their effects potentiated by TCAs like doxepin. Doxepin also may potentiate the adverse effects ... Antihypertensive agents may have their effects mitigated by doxepin. Cotreatment with CNS depressants such as the ...
*  Amitriptyline
Alternative agents, SSRIs and SNRIs, are safer in overdose, though they are no more efficacious than TCAs. English folk singer ... Likewise, cardiac arrhythmias can be treated with propranolol and should heart failure occur, digitalis may be used. Cardiac ... especially after the anti-reflux procedure Nissen fundoplication The known contraindications of amitriptyline are: ... Amitriptyline is the most widely researched agent for prevention of frequent tension headaches. Eating disorders: The few ...