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*  Candesartan
As with other angiotensin II receptor antagonists, candesartan is indicated for the treatment of hypertension. Results from the ... Jul-Aug 1993). "Pilot study of a new angiotensin II receptor antagonist, TCV-116: effects of a single oral dose on blood ... Candesartan (rINN) /ˌkændɪˈsɑːrtən/ is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. The ... 1992). "Hypotensive activity of TCV-116, a newly developed angiotensin II receptor antagonist, in spontaneously hypertensive ...
*  Angiotensin II receptor blocker
... s (ARBs), also known as angiotensin II receptor antagonists , AT1 receptor antagonists or ... These substances are AT1-receptor antagonists; that is, they block the activation of angiotensin II AT1 receptors. Blockage of ... They block the activation of AT1 receptors, preventing the binding of angiotensin II. Angiotensin II receptor blockers are used ... The issue of whether angiotensin II receptor antagonists slightly increase the risk of myocardial infarction (MI or heart ...
*  Angiotensin II receptor type 1
Angiotensin II receptor antagonists are drugs indicated for hypertension, diabetic nephropathy and congestive heart failure. ... Angiotensin II receptor type 1 or AT1 receptor is the best characterized angiotensin receptor. It has vasopressor effects and ... The angiotensin receptor is activated by the vasoconstricting peptide angiotensin II. The activated receptor in turn couples to ... Saavedra JM, Benicky J, Zhou J (2007). "Mechanisms of the Anti-Ischemic Effect of Angiotensin II AT( 1 ) Receptor Antagonists ...
*  Angiotensin II receptor
... antagonist de Gasparo M, Catt KJ, Inagami T, Wright JW, Unger T (2000). "International union of ... The angiotensin II receptors, (AGTR1) and (AGTR2), are a class of G protein-coupled receptors with angiotensin II as their ... The angiotensin receptor is activated by the vasoconstricting peptide angiotensin II. The activated receptor in turn couples to ... The AT4 receptor is activated by the angiotensin II metabolite angiotensin IV, and may play a role in regulation of the CNS ...
*  Discovery and development of angiotensin receptor blockers
The angiotensin receptor blockers (ARBs), also called angiotensin (AT1) receptor antagonists or sartans, are a group of ... 1995), "Synthesis and angiotensin II receptor antagonist activity of C-linked pyrimidine derivatives" (PDF), European Journal ... Two more angiotensin receptors have been described, AT3 and AT4, but their role is still unknown. AT1 receptors are mainly ... Burnier, M.; Brunner, H.R. (2000), "Angiotensin II receptor antagonists" (PDF), Lancet, 355 (9204): 637-645, doi:10.1016/S0140- ...
*  Bezold-Jarisch reflex
Sever, P. S.; Hughes, A. (June 2001). "Angiotensin receptor antagonists and vaso-vagal attacks due to sensitisation of the ... angiotensin II type 1 receptor (AT1) antagonists and serotonin agonists may also elicit the reflex. Vasodepressor syncope or ... However, pressure receptors in the wall and trabeculae of the underfilled left ventricle may then sense stimuli, activating ... presumably by stimulating ventricular receptors. It is possible that these chemical stimuli activate the same stretch-sensitive ...
*  Irbesartan
Angiotensin II receptor antagonist Lewis EJ, Hunsicker LG, Clarke WR, Berl T, Pohl MA, Lewis JB, Ritz E, Atkins RC, Rohde R, ... As with all angiotensin II receptor antagonists, irbesartan is indicated for the treatment of hypertension. It may also delay ... Irbesartan (INN) /ɜːrbəˈsɑːrtən/ is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. It was ... 2001). "Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 ...
*  Telmisartan
... (INN) /tɛlmɪˈsɑːrtən/ is an angiotensin II receptor antagonist (angiotensin receptor blocker, ARB) used in the ... Telmisartan is an angiotensin II receptor blocker that shows high affinity for the angiotensin II receptor type 1 (AT1), with a ... Side effects are similar to other angiotensin II receptor antagonists and include tachycardia and bradycardia (fast or slow ... "Identification of Telmisartan as a Unique Angiotensin II Receptor Antagonist with Selective PPAR -Modulating Activity". ...
*  Losartan
It is in the angiotensin II receptor antagonist family of medication and works by blocking angiotensin II. Losartan was ... competitive angiotensin II receptor type 1 (AT1) antagonist, reducing the end organ responses to angiotensin II. Losartan ... As with all angiotensin II type 1 receptor (AT1) antagonists, losartan is used to treatment hypertension. It may also delay ... Losartan and other angiotensin-receptor antagonists exhibit fetal toxicity and should be avoided during pregnancy, particularly ...
*  Tasosartan
... is an angiotensin II receptor antagonist. It was withdrawn from FDA review by the manufacturer after phase III ... ISBN 0-12-369417-5. Dina R, Jafari M (July 2000). "Angiotensin II-receptor antagonists: an overview". Am J Health Syst Pharm. ...
*  Antihypertensive drug
Angiotensin II receptor antagonists work by antagonizing the activation of angiotensin receptors. azilsartan candesartan ... On the other hand, β-blockers, diuretics, ACE inhibitors, angiotensin receptor blockers, and aldosterone receptor antagonists ... Aldosterone receptor antagonists: eplerenone spironolactone Aldosterone receptor antagonists are not recommended as first-line ... However, ACE inhibitors (and angiotensin II receptor antagonists) should not be a first-line treatment for black hypertensives ...
*  Andrew Stewart Coats
... angiotensin receptor antagonist in heart failure), and SENIORS (management of heart failure in the elderly). He has published ...
*  Amlodipine
Olmesartan is an angiotensin II receptor antagonist and blocks part of the RAAS pathway. Amlodipine/perindopril if using ... Amlodipine/valsartan or amlodipine/valsartan/hydrochlorothiazide, where valsartan is an angiotensin II receptor antagonist. The ... Amlodipine/telmisartan, where telmisartan is an Angiotensin II receptor antagonist. ... Amlodipine has additionally been found to act as an antagonist of the mineralocorticoid receptor, or as an ...
*  Calcium channel blocker
ACE inhibitor Angiotensin II receptor antagonist Nitrate Tfelt-Hansen, P; Tfelt-Hansen, J (2009). "Verapamil for cluster ... Calcium channel blockers (CCB), calcium channel antagonists or calcium antagonists are several medications that disrupt the ... The lower levels of vasopressin from the consumption of alcohol have been linked to ethanol acting as an antagonist to voltage- ... Calcium Channel Antagonists". Poisoning & drug overdose (6th ed.). McGraw-Hill Medical. ISBN 0071668330. "calcium channel ...
*  History of hypertension
February 1996). "Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy". J. Med. Chem ... More recently angiotensin receptor blockers and renin inhibitors have also been introduced as antihypertensive agents. Esunge ... Black JW, Crowther AF, Shanks RG, Smith LH, Dornhorst AC (May 1964). "A new adrenergic beta receptor antagonist". Lancet. 1 ( ... The renin-angiotensin system was known to play an important role in blood pressure regulation, and angiotensin converting ...
*  Valsartan
It is an angiotensin II receptor antagonist (commonly called an ARB, or angiotensin receptor blocker), that is selective for ... Angiotensin II receptor antagonist Discovery and development of angiotensin receptor blockers Valsartan/hydrochlorothiazide ... The drug binds to angiotensin type I receptors (AT1), working as an antagonist. This mechanism of action is different than that ... As valsartan acts at the receptor, it can provide more complete angiotensin II antagonism since angiotensin II is generated by ...
*  Renin inhibitor
... design Angiotensin Angiotensin II receptor antagonist Beta blocker Circulatory system Discovery and development of angiotensin ... and similar to angiotensin II receptor antagonists. Ang II also functions within the RAAS as a negative feedback to suppress ... This can be problematic for ACE inhibitor and angiotensin II receptor antagonist therapy since increased PRA could partially ... A reduction in Ang II levels or blockade of angiotensin receptors will suppress the feedback loop and lead to increased plasma ...
*  Forasartan
... , otherwise known as the compound SC-52458, is a nonpeptide angiotensin II receptor antagonist (ARB, AT1 receptor ... "an Orally Active Angiotensin II-Receptor Antagonist: Inhibition of Blood Pressure Response to Angiotensin II Challenges and ... McMahon, EG; Yang PC (1997). "Effects of SC-52458, an Angiotensin AT1 Receptor Antagonist, in the Dog". American Journal of ... Usune, S; Furukawa T (1996). "Effects of SC-52458, a New Nonpeptide Angiotensin II Receptor Antagonist, on Increase in ...
*  Olmesartan
In studies of angiotensin II receptor antagonists such as olmesartan, patients with unilateral or bilateral renal artery ... Olmesartan medoxomil is an angiotensin II receptor antagonist which is used for the treatment of high blood pressure. It was ... "An update on non-peptide angiotensin receptor antagonists and related RAAS modulators", Life Sci., 81 (8): 615-39, doi:10.1016/ ... "Olmesartan is More Effective Than Other Angiotensin Receptor Antagonists in Reducing Proteinuria in Patients With Chronic ...
*  ACE inhibitor
Angiotensin II receptor antagonist Discovery and development of angiotensin receptor blockers Loop diuretic, also used to treat ... angiotensin II receptor antagonists may be useful because they act to prevent the action of angiotensin II at the AT1 receptor ... "Pregnancy Outcome Following Exposure to Angiotensin-Converting Enzyme Inhibitors or Angiotensin Receptor Antagonists: A ... The combination therapy of angiotensin II receptor antagonists with ACE inhibitors may be superior to either agent alone. This ...
*  Management of heart failure
Angiotensin II receptor antagonist therapy (also referred to as AT1-antagonists or angiotensin receptor blockers), particularly ... other than ACE inhibitors or angiotensin II receptor antagonists, with proven survival benefits. This combination appears to be ... "Angiotensin receptor blockers for heart failure". Cochrane Database of Systematic Reviews. 4 (23): CD003040. doi:10.1002/ ... 2001). "A randomized trial of the angiotensin-recepto blocker valsartan in chronic heart failure". N Engl J Med. 345 (23): 1667 ...
*  Beta blocker
... while ACE inhibitors and angiotensin II receptor antagonists (angiotensin receptor blockers) actually decrease the risk of ... β2 and β3 receptors. β1-adrenergic receptors are located mainly in the heart and in the kidneys. β2-adrenergic receptors are ... β3-adrenergic receptors are located in fat cells. Beta receptors are found on cells of the heart muscles, smooth muscles, ... Beta blockers are competitive antagonists that block the receptor sites for the endogenous catecholamines epinephrine ( ...
*  Eprosartan
... is an angiotensin II receptor antagonist used for the treatment of high blood pressure. It is marketed in the United ... As with other angiotensin II receptor antagonists, eprosartan is generally better tolerated than enalapril (an ACE inhibitor), ... First, it blocks the binding of angiotensin II to AT1 receptors in vascular smooth muscle, causing vascular dilatation. Second ... Discovery and development of angiotensin receptor blockers Anon., 2006, Abbott Laboratories: Kos Pharmaceuticals a wise buy, ...
*  Myocardial infarction
Those who cannot tolerate ACE inhibitors may be treated with an angiotensin II receptor antagonist. Statin therapy has been ... Aldosterone antagonists (spironolactone or eplerenone) may be used if there is evidence of left ventricular dysfunction after ... In very high-risk scenarios, inhibitors of the platelet glycoprotein αIIbβ3a receptor such as eptifibatide or tirofiban may be ...
*  ARA
... more often called angiotensin receptor blocker (ARB) Aldosterone receptor antagonist (mineralocorticoid receptor antagonist, ... a former local government council in New Zealand Angiotensin II receptor antagonist, ...
*  List of DuPont Experimental Station inventions
... and screens Building 400 Hyzaar combination drug to treat hypertension Cozaar Losartan angiotensin II receptor antagonist to ...